Effect of calorie restriction supplemented with genistein on serum levels of glucose, lipid profile and inflammatory markers (resistin and hsCRP) in obese rats

Asian Journal of Biochemistry

Volumn 7, Issue 2, 2012, Pages 98-105

  Mohammad Shahi, M ^a   Rafiei, H ^a   Karandish, M ^a   Omidian, K ^a   Haidari, F ^a  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Genistein; Inflammatory markers; Lipid profile; Obesity

Indexed keywords

ANIMALIA; RATTUS;

EID: 84858048144     PISSN: 18159923     EISSN: None     Source Type: Journal    
DOI: 10.3923/ajb.2012.98.105     Document Type: Article

References (28)

1. Amani, R., J. Baghdadchi and A. Zand-moghaddam, 2005. Effects of soy protein isoflavones on serum lipids, lipoprotein profile and serum glucose of hypercholesterolemia rabbits. Int. J. Endocrinol. Metab., 2: 87-92.
2. Astrup, A., J. Dyerberg, M. Selleck and S. Stender, 2008. Nutrition transition and its relationship to the development of obesity and related chronic diseases. Obese Rev., 9: 48-52.
3. Banz, W.J., J. Davis, R. Peterson and M.J. Iqbal, 2004. Gene expression and adiposity are modified by soy protein in male Zucker diabetic fatty rats. Obese Res., 12: 1907-1913.
4. Cederroth, C.R., M. Vinciguerra, A. Gjinovci, F. Kuhne and M. Klein et al., 2008. Dietary phytoestrogens activate AMP-activated protein kinase with improvement in lipid and glucose metabolism. Diabetes, 57: 1176-1185.
5. Chen, S.W., H.M. Zhang, L.S. Zhang and X.F. Feng, 2006. Effects of soy isoflavone on gene expression of resistin in insulin-resistance rats. Sichuan Da. Xue. Xue. Bao. Yi. Xue. Ban., 37: 717-720.
6. Cope, M.B., J.W. Jr. Erdman and D.B. Allison, 2008. The potential role of soyfoods in weight and adiposity reduction: An evidence-based review. Obese Rev., 9: 219-235.
7. Guo, Y., G. Wu, X. Su, H. Yang and J. Zhang, 2009. Antiobesity action of a daidzein derivative on male obese mice induced by a high-fat diet. Nutr. Res., 29: 656-663.
8. Jenkins, D, C.W. Kendall, P.W. Conelly, C.J. Jackson, T. Parker, D. Faulkner and E. Vidgen, 2002. Effects ofhigh-and low-isoflavone (phytoestrogen) soyfoods on inflammatory biomarkers and pro inflammatory cytokines in middle-aged men and women. Metabolism, 51: 919-924.
9. Jones, K.L., J. Harty, M.J. Roeder, T.A. Winters and W.J. Banz, 2005. In vitro effects of soy phytoestrogens on rat L6 skeletal muscle cells. J. Med. Food, 8: 327-331.
10. Kim, S, H.J. Shin, S.Y. Kim, J.H. Kim, Y.S. Lee, D.H. Kim and M.O. Lee, 2004. Genistein enhances expression of genes involved in fatty acid catabolism through activation of PPARalpha. Mol. Cell. Endocrinol, 220: 51-58.
11. Kirk, E.A, P. Sutherland, SA. Wang, A. Chait and R.C. LeBoeuf, 1998. Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-de?cient mice. J. Nutr, 128: 954-959.
12. Kishida, T, T. Mizushige, Y. Ohtsu, S. Ishikawa and M. Nagamoto et al., 2008. Dietary soy isoflavone-aglycone lowers food intake in female rats with and without ovariectomy. Obesity, 16: 290-297.
13. Kopelman, P.G, 2000. Obesity as a medical problem. Nature, 404: 635-643.
14. Lazar, M.A, 2005. How obesity causes diabetes: Not a tall tale. Science, 307: 373-375.
15. Lee, J.S, 2006. Effects of soy protein and genistein on blood glucose, antioxidant enzyme activities and lipid profile in streptozotocin-induced diabetic rats. Life Sci, 79: 1578-1584.
16. Mezei, O, W.J. Banz, R.W. Steger, M.R. Peluso, T.A. Winters and N. Shay, 2003. Soy isoflavones exert antidiabetic and hypolipidemic effects through the PPAR pathways in obese Zucker rats and murine RAW 264.7 cells. J. Nutr, 133: 1238-1343.
17. Mohammad Shahi, M, M.R. Rashidi, S.A. Mahboob, F. Haidari, B. Rashidi and J. Hanaee, 2011. Protective effect of soy protein on collagen-induced arthritis in rat. Rheumatol. Int., 10.1007/s00296-011-1979-7
18. Mullen, E, R.M. Brown, T.F. Osborne and N.F. Shay, 2004. Soy isoflavones affect sterol regulatory element binding proteins (SREBPs) and SREBP-regulated genes in HepG2 cells. J. Nutr, 134: 2942-2947.
19. Naaz, A, S. Yellayi, A. Melissa, A. Zakaroczimsky, D. Bunick and R. Daniel, 2008. The Soy isoflavone genistein decreases adipose deposition in mice. Endocrinology, 144: 3315-3320.
20. Ogden, C.L, M.D. Carroll, L.R. Curtin, M.A. McDowell, C.J. Tabak and KM. Flegal, 2006. Prevalence of overweight and obesity in the United States, 1999-2004. J. Am. Med. Assoc, 295: 1549-1555.
21. Orgaard, A. and L. Jensen, 2008. The effects of soy isoflavones on obesity. Exp. Biol. Med, 233: 1066-1080.
22. Owen, A.J, P.D. Roach and M. Abbey, 2004. Regulation of low-density lipoprotein receptor activity by estrogens and phytoestrogens in a HepG2 cell model. Ann. Nutr. Metab, 48: 269-275.
23. Rayalam, S, M.A. Della-Fera and OA. Baile, 2008. Phytochemicals and regulation of the adipocyte life cycle. J. Nutr. Biochem, 19: 717-726.
24. Reinli, K. and G. Block, 1996. Phytoestrogen content of foods-a compendium of literature values. Nutr. Cancer, 26: 123-148.
25. Selvin, E, N.P. Paynter and T.P. Erlinger, 2007. The effect of weight loss on C-reactive protein: A systematic review. Arch. Int. Med, 167: 31-39.
26. Setchell, K.D, L. Zimmer-Nechemias, J. Cai and J.E. Heubi, 1997. Exposure of infants to phyto-oestrogens from soy-based infant formula. Lancet, 350: 23-27.
27. Yildiz, M.F, S. Kumru, A. Godekmerdan and S. Kutlu, 2005. Effects of raloxifene, hormone therapy and soy isoflavone on serum high-sensitive C-reactive protein in postmenopausal women. Int. J. Gynecol. Obstet, 90: 128-133.
28. Zimmermann-Belsing, T. and U. Feldt-Rasmussen, 2004. Obesity: The new worldwide epidemic threat to general health and our complete lack of effective treatment. Endocrinology, 145: 1501-1502.