메뉴 건너뛰기




Volumn 48, Issue 4, 2004, Pages 269-275

Regulation of low-density lipoprotein receptor activity by estrogens and phytoestrogens in a HepG2 cell model

Author keywords

Antioxidant; Estrogen; Isoflavone; Low density lipoprotein; Phytoestrogen; Receptor, LDL

Indexed keywords

BIOCHANIN A; COUMESTROL; DAIDZEIN; ENTERODIOL; ENTEROLACTONE; ESTRADIOL; ESTRIOL; FORMONONETIN; ISOFLAVONOID; LIGNAN DERIVATIVE; LOW DENSITY LIPOPROTEIN RECEPTOR; PHYTOESTROGEN;

EID: 6044231038     PISSN: 02506807     EISSN: None     Source Type: Journal    
DOI: 10.1159/000080462     Document Type: Article
Times cited : (31)

References (49)
  • 1
    • 0026072558 scopus 로고
    • Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins
    • Walsh BW, Schiff I, Rosner B, Greenberg L, Ravnikar V, Sacks F: Effects of postmenopausal estrogen replacement on the concentrations and metabolism of plasma lipoproteins. N Engl J Med 1991;325:1196-1204.
    • (1991) N Engl J Med , vol.325 , pp. 1196-1204
    • Walsh, B.W.1    Schiff, I.2    Rosner, B.3    Greenberg, L.4    Ravnikar, V.5    Sacks, F.6
  • 2
    • 0348038714 scopus 로고    scopus 로고
    • The role of estrogen and estrogen-related drugs in cardiovascular diseases
    • Ogita H, Node K, Kitakaze M: The role of estrogen and estrogen-related drugs in cardiovascular diseases. Curr Drug Metab 2003;4:497-504.
    • (2003) Curr Drug Metab , vol.4 , pp. 497-504
    • Ogita, H.1    Node, K.2    Kitakaze, M.3
  • 3
    • 0026779442 scopus 로고
    • The effect of estrogen on the female cardiovascular system
    • Wren BG: The effect of estrogen on the female cardiovascular system. Med J Aust 1992;157:204-208.
    • (1992) Med J Aust , vol.157 , pp. 204-208
    • Wren, B.G.1
  • 4
    • 0018607971 scopus 로고
    • Hepatic catabolism of rat and human lipoproteins in rats treated with 17α-ethinyl estradiol
    • Chao Y, Windler EH, Chen GC, Havel RJ: Hepatic catabolism of rat and human lipoproteins in rats treated with 17α-ethinyl estradiol. J Biol Chem 1979;254:11360-11366.
    • (1979) J Biol Chem , vol.254 , pp. 11360-11366
    • Chao, Y.1    Windler, E.H.2    Chen, G.C.3    Havel, R.J.4
  • 5
    • 0022253230 scopus 로고
    • Solubilisation of the 17-alpha ethinyl estradiol-stimulated low density lipoprotein receptor of male rat liver
    • Roach PD, Noel S-P: Solubilisation of the 17-alpha ethinyl estradiol-stimulated low density lipoprotein receptor of male rat liver. J Lipid Res 1985;26:713-720.
    • (1985) J Lipid Res , vol.26 , pp. 713-720
    • Roach, P.D.1    Noel, S.-P.2
  • 6
    • 0022456499 scopus 로고
    • Increased mRNA for low density lipoprotein receptor in livers of rabbits treated with 17α-ethinyl estradiol
    • Ma PTS, Yamamoto T, Goldstein JL, Brown MS: Increased mRNA for low density lipoprotein receptor in livers of rabbits treated with 17α-ethinyl estradiol. Proc Natl Acad Sci USA 1986;83:792-796.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 792-796
    • Ma, P.T.S.1    Yamamoto, T.2    Goldstein, J.L.3    Brown, M.S.4
  • 7
    • 0018102459 scopus 로고
    • Effect of estrogens on rat serum cholesterol concentrations: Consideration of dose, type of estrogen and treatment duration
    • Ferreri F, Naito NK: Effect of estrogens on rat serum cholesterol concentrations: Consideration of dose, type of estrogen and treatment duration. Endocrinology 1978;102:1621-1627.
    • (1978) Endocrinology , vol.102 , pp. 1621-1627
    • Ferreri, F.1    Naito, N.K.2
  • 9
    • 0023189973 scopus 로고
    • Estrogens induce low density lipoprotein receptor activity and decrease intracellular cholesterol in human hepatoma cell line HepG2
    • Semenkovich CF, Ostlund RE Jr: Estrogens induce low density lipoprotein receptor activity and decrease intracellular cholesterol in human hepatoma cell line HepG2. Biochemistry 1987;26:4987-4992.
    • (1987) Biochemistry , vol.26 , pp. 4987-4992
    • Semenkovich, C.F.1    Ostlund Jr., R.E.2
  • 10
    • 0027501388 scopus 로고
    • The effects of hypercholesterolaemia, simvastatin and dietary fat on the low density lipoprotein receptor of unstimulated mononuclear cells
    • Roach PD, Hosking J, Clifton PM, Bais R, Kusenic B, Coyle P, Wight MB, Thomas DW, Nestel PJ: The effects of hypercholesterolaemia, simvastatin and dietary fat on the low density lipoprotein receptor of unstimulated mononuclear cells. Atherosclerosis 1993;103:245-254.
    • (1993) Atherosclerosis , vol.103 , pp. 245-254
    • Roach, P.D.1    Hosking, J.2    Clifton, P.M.3    Bais, R.4    Kusenic, B.5    Coyle, P.6    Wight, M.B.7    Thomas, D.W.8    Nestel, P.J.9
  • 11
    • 0032748784 scopus 로고    scopus 로고
    • Effects of menopause and hormone replacement therapy on plasma lipids, lipoproteins and LDL receptor activity
    • Abbey M, Owen A, Suzukawa M, Roach P, Nestel PJ: Effects of menopause and hormone replacement therapy on plasma lipids, lipoproteins and LDL receptor activity. Maturitas 1999;33:259-269.
    • (1999) Maturitas , vol.33 , pp. 259-269
    • Abbey, M.1    Owen, A.2    Suzukawa, M.3    Roach, P.4    Nestel, P.J.5
  • 12
    • 84979134159 scopus 로고
    • Infertility in sheep grazing on subterranean clover pastures. Observations on breeding behaviour following transfer to 'sound' country
    • Schinckel PG: Infertility in sheep grazing on subterranean clover pastures. Observations on breeding behaviour following transfer to 'sound' country. Aust Vet J 1948;24:289-294.
    • (1948) Aust Vet J , vol.24 , pp. 289-294
    • Schinckel, P.G.1
  • 13
    • 0028966126 scopus 로고
    • Estrogen-specific 17β-hydroxysteroid oxidoreductase type 1 (EC 1.1.1.62) as a possible target for the action of phytoestrogens
    • Makela S, Poutanen M, Lehtimaki J, Kostian M-L, Santti R, Vihko R: Estrogen-specific 17β-hydroxysteroid oxidoreductase type 1 (EC 1.1.1.62) as a possible target for the action of phytoestrogens. Proc Soc Exp Biol Med 1995;208:51-59.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 51-59
    • Makela, S.1    Poutanen, M.2    Lehtimaki, J.3    Kostian, M.-L.4    Santti, R.5    Vihko, R.6
  • 14
    • 0030889085 scopus 로고    scopus 로고
    • The estrogenic and antiestrogenic activities of phytochemicals with the human estrogen receptor expressed in yeast
    • Collins BM, McLachlan JA, Arnold SF: The estrogenic and antiestrogenic activities of phytochemicals with the human estrogen receptor expressed in yeast. Steroids 1997;62:365-372.
    • (1997) Steroids , vol.62 , pp. 365-372
    • Collins, B.M.1    McLachlan, J.A.2    Arnold, S.F.3
  • 15
    • 0033040051 scopus 로고    scopus 로고
    • Potential tissue selectivity of dietary phytoestrogens and estrogens
    • Cassidy A: Potential tissue selectivity of dietary phytoestrogens and estrogens. Curr Opin Lipid 1999;10:47-52.
    • (1999) Curr Opin Lipid , vol.10 , pp. 47-52
    • Cassidy, A.1
  • 16
    • 0017261006 scopus 로고
    • Hypolipidemic principles of cicer arietinum: Biochanin A and formononetin
    • Siddiqui MT, Siddiqi M: Hypolipidemic principles of cicer arietinum: Biochanin A and formononetin. Lipids 1976;11:243-246.
    • (1976) Lipids , vol.11 , pp. 243-246
    • Siddiqui, M.T.1    Siddiqi, M.2
  • 17
    • 0029783075 scopus 로고    scopus 로고
    • Soy protein and serum lipids
    • Potter SM: Soy protein and serum lipids. Curr Opin Lipid 1996;7:260-264.
    • (1996) Curr Opin Lipid , vol.7 , pp. 260-264
    • Potter, S.M.1
  • 19
    • 0003102231 scopus 로고    scopus 로고
    • Regulation of the low density lipoprotein receptor by antioxidants
    • Basu TK, Temple N, Garg MM (eds): Oxford, CABI
    • Pal S, Bursill C, Bottema C, Roach PD: Regulation of the low density lipoprotein receptor by antioxidants; in Basu TK, Temple N, Garg MM (eds): Antioxidants in Human Health and Disease. Oxford, CABI, 1999, pp 55-69.
    • (1999) Antioxidants in Human Health and Disease , pp. 55-69
    • Pal, S.1    Bursill, C.2    Bottema, C.3    Roach, P.D.4
  • 22
    • 0024550456 scopus 로고
    • Continuous monitoring of in vitro oxidation of human low density lipoprotein
    • Esterbauer H, Streigl G, Puhl H, Rotheneder M: Continuous monitoring of in vitro oxidation of human low density lipoprotein. Free Radic Res Commun 1989;6:67-75.
    • (1989) Free Radic Res Commun , vol.6 , pp. 67-75
    • Esterbauer, H.1    Streigl, G.2    Puhl, H.3    Rotheneder, M.4
  • 23
    • 0024600318 scopus 로고
    • Regulation of prolactin synthesis in vitro by estrogenic and antiestrogenic derivatives of estradiol and estrone
    • Jordan C, Koch R: Regulation of prolactin synthesis in vitro by estrogenic and antiestrogenic derivatives of estradiol and estrone. Endocrinology 1989;124:1717-1726.
    • (1989) Endocrinology , vol.124 , pp. 1717-1726
    • Jordan, C.1    Koch, R.2
  • 25
    • 0032104067 scopus 로고    scopus 로고
    • Antioxidant protection of LDL by physiologic concentrations of estrogens is specific for 17-beta-estradiol
    • Shwaery GT, Vita JA, Keaney JF Jr: Antioxidant protection of LDL by physiologic concentrations of estrogens is specific for 17-beta-estradiol. Atherosclerosis 1998;138:255-262.
    • (1998) Atherosclerosis , vol.138 , pp. 255-262
    • Shwaery, G.T.1    Vita, J.A.2    Keaney Jr., J.F.3
  • 26
    • 0030857452 scopus 로고    scopus 로고
    • Androgen receptor-mediated antagonism of estrogen-dependent low density lipoprotein receptor transcription in cultured hepatocytes
    • Croston GE, Milan LB, Marschke KB, Reichman M, Briggs MR: Androgen receptor-mediated antagonism of estrogen-dependent low density lipoprotein receptor transcription in cultured hepatocytes. Endocrinology 1997;138:3779-3786.
    • (1997) Endocrinology , vol.138 , pp. 3779-3786
    • Croston, G.E.1    Milan, L.B.2    Marschke, K.B.3    Reichman, M.4    Briggs, M.R.5
  • 28
    • 0030889085 scopus 로고    scopus 로고
    • The estrogenic and antiestrogenic activities of phytochemicals with the human estrogen receptor expressed in yeast
    • Collins BM, McLachlan JA, Arnold SF: The estrogenic and antiestrogenic activities of phytochemicals with the human estrogen receptor expressed in yeast. Steroids 1997;62:365-372.
    • (1997) Steroids , vol.62 , pp. 365-372
    • Collins, B.M.1    McLachlan, J.A.2    Arnold, S.F.3
  • 30
    • 0032502689 scopus 로고    scopus 로고
    • Estrogen regulation of the apolipoprotein AI gene promoter through transcription cofactor sharing
    • Harnish DC, Evans MJ, Scicchitano MS, Bhat RA, Karathanasis SK: Estrogen regulation of the apolipoprotein AI gene promoter through transcription cofactor sharing. J Biol Chem 1998;273:9270-9278.
    • (1998) J Biol Chem , vol.273 , pp. 9270-9278
    • Harnish, D.C.1    Evans, M.J.2    Scicchitano, M.S.3    Bhat, R.A.4    Karathanasis, S.K.5
  • 31
    • 0022851556 scopus 로고
    • Estrogen memory effect in human hepatocytes during repeated cell division without hormone
    • Tam S-P, Hache RJG, Deeley RG: Estrogen memory effect in human hepatocytes during repeated cell division without hormone. Science 1986;234:1234-1237.
    • (1986) Science , vol.234 , pp. 1234-1237
    • Tam, S.-P.1    Hache, R.J.G.2    Deeley, R.G.3
  • 32
    • 0025602506 scopus 로고
    • Estrogen and androgen regulation of sex hormone binding globulin secretion by a human liver cell line
    • Edmunds SEJ, Stubbs AP, Santos AA, Wilkinson ML: Estrogen and androgen regulation of sex hormone binding globulin secretion by a human liver cell line. J Steroid Biochem Molec Biol 1990;37:733-739.
    • (1990) J Steroid Biochem Molec Biol , vol.37 , pp. 733-739
    • Edmunds, S.E.J.1    Stubbs, A.P.2    Santos, A.A.3    Wilkinson, M.L.4
  • 34
    • 0032965145 scopus 로고    scopus 로고
    • Estrogen receptor β activates the human retinoic acid receptor α-1 promoter in response to tamoxifen and other estrogen antagonists, but not in response to estrogen
    • Zou A, Marschke KB, Arnold KE, Berger EM, Fitzgerald P, Mais DE, Allegretto EA: Estrogen receptor β activates the human retinoic acid receptor α-1 promoter in response to tamoxifen and other estrogen antagonists, but not in response to estrogen. Mol Endocinol 1999;13:418-430.
    • (1999) Mol Endocinol , vol.13 , pp. 418-430
    • Zou, A.1    Marschke, K.B.2    Arnold, K.E.3    Berger, E.M.4    Fitzgerald, P.5    Mais, D.E.6    Allegretto, E.A.7
  • 35
    • 0032006237 scopus 로고    scopus 로고
    • Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid
    • Prasad K, Mantha SV, Muir AD, Westcott ND: Reduction of hypercholesterolemic atherosclerosis by CDC-flaxseed with very low alpha-linolenic acid. Atherosclerosis 1998;136:367-375.
    • (1998) Atherosclerosis , vol.136 , pp. 367-375
    • Prasad, K.1    Mantha, S.V.2    Muir, A.D.3    Westcott, N.D.4
  • 36
    • 0028786569 scopus 로고
    • Yeast two-hybrid system demonstrates that estrogen receptor dimerization is ligand-dependent in vivo
    • Wang H, Peters GA, Zeng X, Tang M, Ip W, Khan SA: Yeast two-hybrid system demonstrates that estrogen receptor dimerization is ligand-dependent in vivo. J Biol Chem 1995;270:23322-23329.
    • (1995) J Biol Chem , vol.270 , pp. 23322-23329
    • Wang, H.1    Peters, G.A.2    Zeng, X.3    Tang, M.4    Ip, W.5    Khan, S.A.6
  • 37
  • 38
    • 0033400047 scopus 로고    scopus 로고
    • Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone
    • Kitts DD, Yuan YV, Wijewickreme AN, Thompson LU: Antioxidant activity of the flaxseed lignan secoisolariciresinol diglycoside and its mammalian lignan metabolites enterodiol and enterolactone. Mol Cell Biochem 1999;202:91-100.
    • (1999) Mol Cell Biochem , vol.202 , pp. 91-100
    • Kitts, D.D.1    Yuan, Y.V.2    Wijewickreme, A.N.3    Thompson, L.U.4
  • 39
    • 0031814876 scopus 로고    scopus 로고
    • Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-deficient mice
    • Kirk EA, Sutherland P, Wang SA, Chait A, LeBoeuf RC: Dietary isoflavones reduce plasma cholesterol and atherosclerosis in C57BL/6 mice but not LDL receptor-deficient mice. J Nutr 1998;128:954-959.
    • (1998) J Nutr , vol.128 , pp. 954-959
    • Kirk, E.A.1    Sutherland, P.2    Wang, S.A.3    Chait, A.4    LeBoeuf, R.C.5
  • 41
    • 0031560942 scopus 로고    scopus 로고
    • Lovastatin increases surface LDL receptor expression by retarding the receptor internalisation rate in proliferating lymphocytes
    • Chan P-C, Lafreniere R, Parsons HG: Lovastatin increases surface LDL receptor expression by retarding the receptor internalisation rate in proliferating lymphocytes. Biochem Biophys Res Commun 1997;235:117-122.
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 117-122
    • Chan, P.-C.1    Lafreniere, R.2    Parsons, H.G.3
  • 42
    • 0036711611 scopus 로고    scopus 로고
    • Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion fromHepG2 cells through multiple mechanisms
    • Borradaile NM, DeDreu LE, Wilcox LJ, Edwards JY, Huff MW: Soya phytoestrogens, genistein and daidzein, decrease apolipoprotein B secretion fromHepG2 cells through multiple mechanisms. Biochem J 2002;366:531-539.
    • (2002) Biochem J , vol.366 , pp. 531-539
    • Borradaile, N.M.1    DeDreu, L.E.2    Wilcox, L.J.3    Edwards, J.Y.4    Huff, M.W.5
  • 43
    • 0033082824 scopus 로고    scopus 로고
    • Antioxidant property of dietary phenolic agents in a human LDL oxidation ex vivo model: Interaction of protein binding activity
    • Wang W, Goodman MT: Antioxidant property of dietary phenolic agents in a human LDL oxidation ex vivo model: Interaction of protein binding activity Nutr Res 1999;19:191-202.
    • (1999) Nutr Res , vol.19 , pp. 191-202
    • Wang, W.1    Goodman, M.T.2
  • 44
    • 0028959192 scopus 로고
    • Estrogenic flavonoids: Structural requirements for biological activity
    • Miksicek RJ: Estrogenic flavonoids: Structural requirements for biological activity. Proc Soc Exp Biol Med 1995;208:44-50.
    • (1995) Proc Soc Exp Biol Med , vol.208 , pp. 44-50
    • Miksicek, R.J.1
  • 45
    • 0025165019 scopus 로고
    • HepG2 cells as a resource for metabolic studies: Lipoprotein, cholesterol and bile acids
    • Javitt NB: HepG2 cells as a resource for metabolic studies: Lipoprotein, cholesterol and bile acids. FASEB J 1990;4:161-168.
    • (1990) FASEB J , vol.4 , pp. 161-168
    • Javitt, N.B.1
  • 46
    • 0037369915 scopus 로고    scopus 로고
    • Red wine polyphenolics increase LDL receptor expression and activity and suppress the secretion of apoB100 from human HepG2 cells
    • Pal S, Ho N, Santos C, Dubois P, Mamo J, Croft K, Allister E: Red wine polyphenolics increase LDL receptor expression and activity and suppress the secretion of apoB100 from human HepG2 cells. J Nutr 2003;133:700-706.
    • (2003) J Nutr , vol.133 , pp. 700-706
    • Pal, S.1    Ho, N.2    Santos, C.3    Dubois, P.4    Mamo, J.5    Croft, K.6    Allister, E.7
  • 47
    • 0347356614 scopus 로고    scopus 로고
    • Conjugated linoleic acid upregulates LDL receptor gene expression in Hep G2 cells
    • Yu-Poth S, Yin D, Zhao G, Kris-Etherton PM, Etherton TD: Conjugated linoleic acid upregulates LDL receptor gene expression in Hep G2 cells. J Nutr 2004;134:68-71.
    • (2004) J Nutr , vol.134 , pp. 68-71
    • Yu-Poth, S.1    Yin, D.2    Zhao, G.3    Kris-Etherton, P.M.4    Etherton, T.D.5
  • 48
    • 0037134633 scopus 로고    scopus 로고
    • Inhibition of low density lipoprotein oxidation and upregulation of low density lipoprotein receptor in HepG2 cells by tropical plant extracts
    • Salleh MN, Runnie I, Roach PD, Mohamed S, Abeywardena MY: Inhibition of low density lipoprotein oxidation and upregulation of low density lipoprotein receptor in HepG2 cells by tropical plant extracts. J Agric Food Chem 2002;50:3693-3697.
    • (2002) J Agric Food Chem , vol.50 , pp. 3693-3697
    • Salleh, M.N.1    Runnie, I.2    Roach, P.D.3    Mohamed, S.4    Abeywardena, M.Y.5
  • 49
    • 0030941695 scopus 로고    scopus 로고
    • Modulation of LDL receptor mRNA stability by phorbol esters in human liver cell culture models
    • Wilson GM, Roberts EA, Deeley RG: Modulation of LDL receptor mRNA stability by phorbol esters in human liver cell culture models. J Lipid Res 1997;38:437-446.
    • (1997) J Lipid Res , vol.38 , pp. 437-446
    • Wilson, G.M.1    Roberts, E.A.2    Deeley, R.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.