-
1
-
-
0025743216
-
Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice
-
Agrawal S, Temsamani J and Tang JY. Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice. Proceedings of the National Academy of Science USA 1991; 88: 7595-7599.
-
(1991)
Proceedings of the National Academy of Science USA
, vol.88
, pp. 7595-7599
-
-
Agrawal, S.1
Temsamani, J.2
Tang, J.Y.3
-
2
-
-
0029998906
-
Analysis of modified oligonucleotides by capillary electrophoresis in a polyvinylpyrrolidone matrix coupled with electrospray mass spectrometry
-
Barry JP, Muth J, Law SJ, Karger BL and Vouros P. Analysis of modified oligonucleotides by capillary electrophoresis in a polyvinylpyrrolidone matrix coupled with electrospray mass spectrometry. Journal of Chromatography. A 1996; 732: 159-166.
-
(1996)
Journal of Chromatography. A
, vol.732
, pp. 159-166
-
-
Barry, J.P.1
Muth, J.2
Law, S.J.3
Karger, B.L.4
Vouros, P.5
-
3
-
-
0034255206
-
Quantitative determination of a chemically modified hammerhead ribozyme in blood plasma using 96-well solid-phase extraction coupled with high-performance liquid chromatography or capillary gel electrophoresis
-
Bellon L, Maloney L, Zinnen SP, Sandberg JA and Johnson KE. Quantitative determination of a chemically modified hammerhead ribozyme in blood plasma using 96-well solid-phase extraction coupled with high-performance liquid chromatography or capillary gel electrophoresis. Analytical Biochemistry 2000; 238 228-240.
-
(2000)
Analytical Biochemistry
, vol.238
, pp. 228-240
-
-
Bellon, L.1
Maloney, L.2
Zinnen, S.P.3
Sandberg, J.A.4
Johnson, K.E.5
-
4
-
-
33750298564
-
Single-based resolution for oligodeoxynucleotides and their phosphorothioate modifications by replaceable capillary gel electrophoresis
-
Chen R, Luo X, Di X, Li Y, Sun Y and Hu Y. Single-based resolution for oligodeoxynucleotides and their phosphorothioate modifications by replaceable capillary gel electrophoresis. Journal of Chromatography B 2006; 843: 334-338.
-
(2006)
Journal of Chromatography B
, vol.843
, pp. 334-338
-
-
Chen, R.1
Luo, X.2
Di, X.3
Li, Y.4
Sun, Y.5
Hu, Y.6
-
5
-
-
0031741998
-
Use of capillary electrophoresis methods to characterize the pharmacokinetics of antisense drugs
-
Chen SH and Gallo JM. Use of capillary electrophoresis methods to characterize the pharmacokinetics of antisense drugs. Electrophoresis 1998; 19(16-17): 2861-2869.
-
(1998)
Electrophoresis
, vol.19
, Issue.16-17
, pp. 2861-2869
-
-
Chen, S.H.1
Gallo, J.M.2
-
6
-
-
0030963933
-
Determination of antisense phosphorothioate oligonucleotides and catabolites in biological fluids and tissue extracts using anion-exchange high-performance liquid chromatography and capillary gel electrophoresis
-
Chen SH, Qian M, Brennan JM and Gallo JM. Determination of antisense phosphorothioate oligonucleotides and catabolites in biological fluids and tissue extracts using anion-exchange high-performance liquid chromatography and capillary gel electrophoresis. Journal of Chromatography B 1997; 692 43-51.
-
(1997)
Journal of Chromatography B
, vol.692
, pp. 43-51
-
-
Chen, S.H.1
Qian, M.2
Brennan, J.M.3
Gallo, J.M.4
-
7
-
-
0027786912
-
14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats
-
14C-labeled phosphorothioate oligonucleotide ISIS 2105 after intravenous administration to rats. Journal of Pharmacology and Experimental Therapy 1993; 267: 1181-1190.
-
(1993)
Journal of Pharmacology and Experimental Therapy
, vol.267
, pp. 1181-1190
-
-
Cossum, P.A.1
Sasmor, H.2
Dellinger, D.3
Truong, L.4
Cummins, L.5
Owens, S.R.6
Markham, P.M.7
Shea, J.P.8
Crooke, S.9
-
8
-
-
0028183175
-
14C-labeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats
-
14C-labeled phosphorothioate oligonucleotide, ISIS 2105, after intradermal administration to rats. Journal of Pharmacology and Experimental Therapy 1994; 269: 89-94.
-
(1994)
Journal of Pharmacology and Experimental Therapy
, vol.269
, pp. 89-94
-
-
Cossum, P.A.1
Truong, L.2
Owens, S.R.3
Markham, P.M.4
Shea, J.P.5
Crooke, S.T.6
-
12
-
-
0028568244
-
A pharmacokinetic evaluation of 14C-labeled afovirsen sodium in patients with genital warts
-
Crooke ST, Grillone LR, Tendolkar A, Garrett A, Fratkin MJ, Leeds J and Barr WH. A pharmacokinetic evaluation of 14C-labeled afovirsen sodium in patients with genital warts. Clinical Pharmacological Therapy 1994; 56: 641-646.
-
(1994)
Clinical Pharmacological Therapy
, vol.56
, pp. 641-646
-
-
Crooke, S.T.1
Grillone, L.R.2
Tendolkar, A.3
Garrett, A.4
Fratkin, M.J.5
Leeds, J.6
Barr, W.H.7
-
13
-
-
12644302203
-
Pharmacokinetic properties of several novel oligonucleotide analogs in mice
-
Crooke ST, Graham MJ, Zuckerman JE, Brooks D, Conklin BS, Cummins LL, Greig MJ, Guinosso CJ, Kornburst D, Manoharan M, Sasmor HM, Schleich T, Tivel KL and Griffey RH. Pharmacokinetic properties of several novel oligonucleotide analogs in mice. Journal of Pharmacology and Experimental Therapy 1996; 277: 923-937.
-
(1996)
Journal of Pharmacology and Experimental Therapy
, vol.277
, pp. 923-937
-
-
Crooke, S.T.1
Graham, M.J.2
Zuckerman, J.E.3
Brooks, D.4
Conklin, B.S.5
Cummins, L.L.6
Greig, M.J.7
Guinosso, C.J.8
Kornburst, D.9
Manoharan, M.10
Sasmor, H.M.11
Schleich, T.12
Tivel, K.L.13
Griffey, R.H.14
-
14
-
-
0014672877
-
Interferon induction increased through chemical modification of a synthetic polyribonucleotide
-
DeClercq E, Eckstein F and Merigan TC. Interferon induction increased through chemical modification of a synthetic polyribonucleotide. Science 1969; 165: 1137-1139.
-
(1969)
Science
, vol.165
, pp. 1137-1139
-
-
DeClercq, E.1
Eckstein, F.2
Merigan, T.C.3
-
15
-
-
35148860246
-
Reptation of a polymer chain in the presence of fixed obstacles
-
De Gennes PG. Reptation of a polymer chain in the presence of fixed obstacles. Journal of Chemical Physics 1971; 55: 572-579.
-
(1971)
Journal of Chemical Physics
, vol.55
, pp. 572-579
-
-
De Gennes, P.G.1
-
16
-
-
0032043390
-
A matrix for DNA separation: genotyping and sequencing using poly (vinylpyrrolidone) solution in uncoated capillaries
-
Gao Q and Yeung E. A matrix for DNA separation: genotyping and sequencing using poly (vinylpyrrolidone) solution in uncoated capillaries. Analytical Chemistry 1998; 70: 1382-1388.
-
(1998)
Analytical Chemistry
, vol.70
, pp. 1382-1388
-
-
Gao, Q.1
Yeung, E.2
-
17
-
-
0030667690
-
Pharmacokinetics and metabolism in mice of a phosphorothioate oligonucleotide antisense inhibitor of C-raf-1 kinase expression
-
Geary RS, Leeds JM, Fitchett J, Burckin T, Troung L, Spainhour C, Creek M, and Levin AA. Pharmacokinetics and metabolism in mice of a phosphorothioate oligonucleotide antisense inhibitor of C-raf-1 kinase expression. Drug Metabolism and Disposition 1997; 25: 1272-1281.
-
(1997)
Drug Metabolism and Disposition
, vol.25
, pp. 1272-1281
-
-
Geary, R.S.1
Leeds, J.M.2
Fitchett, J.3
Burckin, T.4
Troung, L.5
Spainhour, C.6
Creek, M.7
Levin, A.A.8
-
18
-
-
0033569808
-
A nonradioisotope biomedical assay for intact oligonucleotide and its chain-shortened metabolites used for determination of exposure and elimination half-life of antisense drugs in tissue
-
Geary RS, Matson J and Levin AA. A nonradioisotope biomedical assay for intact oligonucleotide and its chain-shortened metabolites used for determination of exposure and elimination half-life of antisense drugs in tissue. Analytical Biochemistry 1999; 274: 241-248.
-
(1999)
Analytical Biochemistry
, vol.274
, pp. 241-248
-
-
Geary, R.S.1
Matson, J.2
Levin, A.A.3
-
19
-
-
0035119622
-
Absolute bioavailability of 2′-o-(2-methoxyethyl)-modified antisense oligonucleotides following intraduodenal instillation in rats
-
Geary RS, Khatsenko O, Bunker K, Crooke R, Moore M, Burckin T, Truong LA, Sasmor H and Levin AA. Absolute bioavailability of 2′-o-(2-methoxyethyl)-modified antisense oligonucleotides following intraduodenal instillation in rats. Journal of Pharmacology and Experimental Therapy 2001a; 296: 898-904.
-
(2001)
Journal of Pharmacology and Experimental Therapy
, vol.296
, pp. 898-904
-
-
Geary, R.S.1
Khatsenko, O.2
Bunker, K.3
Crooke, R.4
Moore, M.5
Burckin, T.6
Truong, L.A.7
Sasmor, H.8
Levin, A.A.9
-
20
-
-
0035119936
-
Pharmacokinetic properties of 2′-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats
-
Geary RS, Watanabe TA, Truong L, Freier S, Lesnik EA, Sioufi NB, Sasmor H, Manoharan M and Levin AA. Pharmacokinetic properties of 2′-O-(2-methoxyethyl)-modified oligonucleotide analogs in rats. Journal of Pharmacology and Experimental Therapy 2001b; 296: 890-897.
-
(2001)
Journal of Pharmacology and Experimental Therapy
, vol.296
, pp. 890-897
-
-
Geary, R.S.1
Watanabe, T.A.2
Truong, L.3
Freier, S.4
Lesnik, E.A.5
Sioufi, N.B.6
Sasmor, H.7
Manoharan, M.8
Levin, A.A.9
-
21
-
-
10744226217
-
Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2′-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species
-
Geary RS, Yu RZ, Watanabe T, Henry SP, Hardee GE, Chappell A, Matson J, Sasmor H, Cummins L and Levin AA. Pharmacokinetics of a tumor necrosis factor-alpha phosphorothioate 2′-O-(2-methoxyethyl) modified antisense oligonucleotide: comparison across species. Drug Metabolism and Disposition 2003; 31: 1419-1428.
-
(2003)
Drug Metabolism and Disposition
, vol.31
, pp. 1419-1428
-
-
Geary, R.S.1
Yu, R.Z.2
Watanabe, T.3
Henry, S.P.4
Hardee, G.E.5
Chappell, A.6
Matson, J.7
Sasmor, H.8
Cummins, L.9
Levin, A.A.10
-
22
-
-
0030812914
-
Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids
-
Gilar M, Belenky A, Smisek DL, Bourque A and Cohen AS. Kinetics of phosphorothioate oligonucleotide metabolism in biological fluids. Nucleic Acids Research 1997; 25: 3615-3620.
-
(1997)
Nucleic Acids Research
, vol.25
, pp. 3615-3620
-
-
Gilar, M.1
Belenky, A.2
Smisek, D.L.3
Bourque, A.4
Cohen, A.S.5
-
23
-
-
0032440301
-
Study of phosphorothioate-modified oligonucleotide resistance to 3′-exonuclease using capillary electrophoresis
-
Gilar M, Belenky A, Budman Y, Smisek DL and Cohen AS. Study of phosphorothioate-modified oligonucleotide resistance to 3′-exonuclease using capillary electrophoresis. Journal of Chromatography B Biomedical Science Applications 1998; 714: 13-20.
-
(1998)
Journal of Chromatography B Biomedical Science Applications
, vol.714
, pp. 13-20
-
-
Gilar, M.1
Belenky, A.2
Budman, Y.3
Smisek, D.L.4
Cohen, A.S.5
-
24
-
-
0029981690
-
Capillary electrophoresis applied to the determination of some seleno compounds
-
Gilon N and Potin-Gautier M. Capillary electrophoresis applied to the determination of some seleno compounds. Journal of Chromatography. A 1996; 732: 369-376.
-
(1996)
Journal of Chromatography. A
, vol.732
, pp. 369-376
-
-
Gilon, N.1
Potin-Gautier, M.2
-
25
-
-
0035427644
-
Hepatic distribution of a phosphorothioate oligodeoxynucleotide within rodents following intravenous administration
-
Graham MJ, Crooke ST, Lemonidis KM, Gaus HJ, Templin MV and Crooke RM. Hepatic distribution of a phosphorothioate oligodeoxynucleotide within rodents following intravenous administration. Biochemical Pharmacology 2001; 62: 297-306.
-
(2001)
Biochemical Pharmacology
, vol.62
, pp. 297-306
-
-
Graham, M.J.1
Crooke, S.T.2
Lemonidis, K.M.3
Gaus, H.J.4
Templin, M.V.5
Crooke, R.M.6
-
26
-
-
0027163099
-
In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits
-
Griffin LC, Tidmarsh GF, Bock LC and Toole JJ, Leung LL. In vivo anticoagulant properties of a novel nucleotide-based thrombin inhibitor and demonstration of regional anticoagulation in extracorporeal circuits. Blood 1993; 81: 3271-3276.
-
(1993)
Blood
, vol.81
, pp. 3271-3276
-
-
Griffin, L.C.1
Tidmarsh, G.F.2
Bock, L.C.3
Toole, J.J.4
Leung, L.L.5
-
27
-
-
0141535274
-
Gel and polymer-solution mediated separation of biopolymers by capillary electrophoresis
-
Guttman A. Gel and polymer-solution mediated separation of biopolymers by capillary electrophoresis. Journal of Chromatographic Siences 2003; 41: 449-459.
-
(2003)
Journal of Chromatographic Siences
, vol.41
, pp. 449-459
-
-
Guttman, A.1
-
28
-
-
0001186849
-
Artifacts related to sample introduction in capillary gel electrophoresis affecting separation performance and quantitation
-
Guttman A and Schwartz HE. Artifacts related to sample introduction in capillary gel electrophoresis affecting separation performance and quantitation. Analytical Chemistry 1995; 67: 2279-2283.
-
(1995)
Analytical Chemistry
, vol.67
, pp. 2279-2283
-
-
Guttman, A.1
Schwartz, H.E.2
-
29
-
-
0010260923
-
-
Schafer-Neilsen C (ed.). VCH: Weinheim
-
Guttman A, Paulus A, Cohen AS, Karger BL, Rodriguez H and Hancock WS. Electrophoresis'88, Schafer-Neilsen C (ed.). VCH: Weinheim, 1988; 151-159.
-
(1988)
Electrophoresis'88
, pp. 151-159
-
-
Guttman, A.1
Paulus, A.2
Cohen, A.S.3
Karger, B.L.4
Rodriguez, H.5
Hancock, W.S.6
-
30
-
-
0032527182
-
Interfacing of CE in a PVP matrix to ion trap mass spectrometry: analysis of isomeric and structurally related (N-acetylamino)flourine-modified oligonucleotides
-
Harsch A and Vouros P. Interfacing of CE in a PVP matrix to ion trap mass spectrometry: analysis of isomeric and structurally related (N-acetylamino)flourine-modified oligonucleotides. Analytical Chemistry 1998: 70; 3021-3027.
-
(1998)
Analytical Chemistry
, vol.70
, pp. 3021-3027
-
-
Harsch, A.1
Vouros, P.2
-
31
-
-
0025079053
-
Separation of DNA restriction fragments by high performance capillary electrophoresis with low and zero crosslinked polyacrylamide using continuous and pulsed electric fields
-
Heiger DN, Cohen AS and Karger BL. Separation of DNA restriction fragments by high performance capillary electrophoresis with low and zero crosslinked polyacrylamide using continuous and pulsed electric fields. Journal of Chromatography 1990; 516: 33-48.
-
(1990)
Journal of Chromatography
, vol.516
, pp. 33-48
-
-
Heiger, D.N.1
Cohen, A.S.2
Karger, B.L.3
-
32
-
-
0030829919
-
J. Inhibition of coagulation by a phosphorothioate oligonucleotide
-
Henry SP, Novotny W, Leeds J, Auletta C and Kornbrust D J. Inhibition of coagulation by a phosphorothioate oligonucleotide Antisense & Nucleic Acid Drug Development 1997a; 7: 503-510.
-
(1997)
Antisense & Nucleic Acid Drug Development
, vol.7
, pp. 503-510
-
-
Henry, S.P.1
Novotny, W.2
Leeds, J.3
Auletta, C.4
Kornbrust, D.5
-
33
-
-
0030860587
-
Antisense oligonucleotide inhibitors for the treatment of cancer. 2. Toxicologic properties of phosphorothioate oligodeoxynucleotides
-
Henry SP, Monteith D and Levin AA. Antisense oligonucleotide inhibitors for the treatment of cancer. 2. Toxicologic properties of phosphorothioate oligodeoxynucleotides. Anti-Cancer Drug Design 1997b; 12: 395-408.
-
(1997)
Anti-Cancer Drug Design
, vol.12
, pp. 395-408
-
-
Henry, S.P.1
Monteith, D.2
Levin, A.A.3
-
34
-
-
0028266132
-
UV-Transparent, replaceable agarose gels for molecular-sieve (capillary) electrophoresis of proteins and nucleic acids
-
Hjerten S, Srichaiyo T and Palm A. UV-Transparent, replaceable agarose gels for molecular-sieve (capillary) electrophoresis of proteins and nucleic acids. Biomedical Chromatography 1994; 8: 73-76.
-
(1994)
Biomedical Chromatography
, vol.8
, pp. 73-76
-
-
Hjerten, S.1
Srichaiyo, T.2
Palm, A.3
-
35
-
-
0026335873
-
In vivo studies with phosphorothiotate oligonucleotides: pharmacokinetic prologue
-
Iversen P. In vivo studies with phosphorothiotate oligonucleotides: pharmacokinetic prologue. Anticancer Drug Design 1991; 6: 531-538.
-
(1991)
Anticancer Drug Design
, vol.6
, pp. 531-538
-
-
Iversen, P.1
-
36
-
-
0242448013
-
Electrokinetic injection in capillary electrophoresis and its application to the analysis of inorganic compounds
-
Krivácsy AZ, Gelencsér JH, Kiss G and Sárvári ZS. Electrokinetic injection in capillary electrophoresis and its application to the analysis of inorganic compounds. Journal of Chromatography. A 1999; 834: 21-44.
-
(1999)
Journal of Chromatography. A
, vol.834
, pp. 21-44
-
-
Krivácsy, A.Z.1
Gelencsér, J.H.2
Kiss, G.3
Sárvári, Z.S.4
-
37
-
-
85165508318
-
-
Non-clinical regulatory considerations of therapeutic oligonucleotide based agents. AAPS November .
-
Lee SL. Non-clinical regulatory considerations of therapeutic oligonucleotide based agents. AAPS November 2008.
-
(2008)
-
-
Lee, S.L.1
-
38
-
-
0028147760
-
Determintation of metal cations by capillary electrophoresis effect of background carrier and complexing agents
-
Lee YH and Lin TI. Determintation of metal cations by capillary electrophoresis effect of background carrier and complexing agents. Journal of Chromatography. A 1994; 675: 227-236.
-
(1994)
Journal of Chromatography. A
, vol.675
, pp. 227-236
-
-
Lee, Y.H.1
Lin, T.I.2
-
40
-
-
0032088769
-
Quantitation of phosphorothioate oligonucleotides in human blood plasma using a nanoparticle-based method for solid-phase extraction
-
Maier M, Fritz H, Gerster M, Schewitz J and Bayer E. Quantitation of phosphorothioate oligonucleotides in human blood plasma using a nanoparticle-based method for solid-phase extraction. Analytical Chemistry 1998; 70(11): 2197-2204.
-
(1998)
Analytical Chemistry
, vol.70
, Issue.11
, pp. 2197-2204
-
-
Maier, M.1
Fritz, H.2
Gerster, M.3
Schewitz, J.4
Bayer, E.5
-
41
-
-
0030809893
-
Preclinical profiling of modified oligonucleotides: anticoagulation and pharmacokinetic properties
-
Nicklin PL, Ambler J, Mitchelson A, Bailey D, Phillips JA, Craig SJ and Monia BP. Preclinical profiling of modified oligonucleotides: anticoagulation and pharmacokinetic properties. Nucleosides & Nucleotides 1997; 16: 1145-1153.
-
(1997)
Nucleosides & Nucleotides
, vol.16
, pp. 1145-1153
-
-
Nicklin, P.L.1
Ambler, J.2
Mitchelson, A.3
Bailey, D.4
Phillips, J.A.5
Craig, S.J.6
Monia, B.P.7
-
42
-
-
14644427778
-
Biodistribution and metabolism of immunostimulatory oligodeoxynucleotide CPG 7909 in mouse and rat tissues following subcutaneous administration
-
Noll BO, McLuskie MJ, Sniatala T, Lohner A, Yuill S, Kreig AM, Schetter C, Davis HL and Uhlmann E. Biodistribution and metabolism of immunostimulatory oligodeoxynucleotide CPG 7909 in mouse and rat tissues following subcutaneous administration. Biochemical Pharmacology 2005; 69: 981-991.
-
(2005)
Biochemical Pharmacology
, vol.69
, pp. 981-991
-
-
Noll, B.O.1
McLuskie, M.J.2
Sniatala, T.3
Lohner, A.4
Yuill, S.5
Kreig, A.M.6
Schetter, C.7
Davis, H.L.8
Uhlmann, E.9
-
43
-
-
33847318611
-
Identification and quantification of GC-rich oligodeoxynucleotides in tissue extracts by capillary gel electrophoresis
-
Noll BO, Debelak H and Uhlmann E. Identification and quantification of GC-rich oligodeoxynucleotides in tissue extracts by capillary gel electrophoresis. Journal of Chromatography B 2007; 847: 153-161.
-
(2007)
Journal of Chromatography B
, vol.847
, pp. 153-161
-
-
Noll, B.O.1
Debelak, H.2
Uhlmann, E.3
-
44
-
-
0030850579
-
Respirable antisense oligonucleotides as novel therapeutic agents for asthma and other pulmonary diseases
-
Nyce JW. Respirable antisense oligonucleotides as novel therapeutic agents for asthma and other pulmonary diseases. Expert Opinion on Investigation of Drugs 1997; 6: 1149-1156.
-
(1997)
Expert Opinion on Investigation of Drugs
, vol.6
, pp. 1149-1156
-
-
Nyce, J.W.1
-
45
-
-
19444375104
-
DNA-based therapeutics and DNA delivery systems: a comprehensive review
-
Paril SD, Rohdes DG and Burgess DJ. DNA-based therapeutics and DNA delivery systems: a comprehensive review. The AAPS Journal 2005; 7: 1.
-
(2005)
The AAPS Journal
, vol.7
, pp. 1
-
-
Paril, S.D.1
Rohdes, D.G.2
Burgess, D.J.3
-
46
-
-
4043050764
-
Capillary electrophoresis for the analysis of biopolymers
-
Qiugley WWC and Dovichi NJ. Capillary electrophoresis for the analysis of biopolymers. Analytical Chemistry 2004; 76: 4645-4658.
-
(2004)
Analytical Chemistry
, vol.76
, pp. 4645-4658
-
-
Qiugley, W.W.C.1
Dovichi, N.J.2
-
47
-
-
0030573018
-
Determination of single-stranded oligodeoxynucleotides by capillary gel electrophoresis with laser induced fluorescence and on column derivatization
-
Reyderman L and Stavchansky S. Determination of single-stranded oligodeoxynucleotides by capillary gel electrophoresis with laser induced fluorescence and on column derivatization. Journal of Chromatography. A 1996; 755: 271-280.
-
(1996)
Journal of Chromatography. A
, vol.755
, pp. 271-280
-
-
Reyderman, L.1
Stavchansky, S.2
-
48
-
-
0031571343
-
Quantitative determination of short single-stranded oligonucleotides from blood plasma using capillary electrophoresis with laser-induced fluorescence
-
Reyderman L and Stavchansky S. Quantitative determination of short single-stranded oligonucleotides from blood plasma using capillary electrophoresis with laser-induced fluorescence. Analytical Chemistry 1997; 69: 3218-3222.
-
(1997)
Analytical Chemistry
, vol.69
, pp. 3218-3222
-
-
Reyderman, L.1
Stavchansky, S.2
-
49
-
-
0036078673
-
Recent progress in DNA analysis by capillary electrophoresis
-
Righetti PG, Gelfi C and Acunto MR. Recent progress in DNA analysis by capillary electrophoresis. Electrophoresis 2002; 23: 1361-1374.
-
(2002)
Electrophoresis
, vol.23
, pp. 1361-1374
-
-
Righetti, P.G.1
Gelfi, C.2
Acunto, M.R.3
-
50
-
-
0025248128
-
Microinjected oligonucleotides complementary to the alpha-sarcin loop of 28S RNA abolish protein synthesis in Xenopus oocytes
-
Saxena SK and Ackerman EJ. Microinjected oligonucleotides complementary to the alpha-sarcin loop of 28S RNA abolish protein synthesis in Xenopus oocytes. Journal of Biological Chemistry 1990; 265: 3263-3269.
-
(1990)
Journal of Biological Chemistry
, vol.265
, pp. 3263-3269
-
-
Saxena, S.K.1
Ackerman, E.J.2
-
51
-
-
2942568866
-
Detection and quantitation of PS20, a phosphorothioate oligodeoxynucleotides in monkey plasma
-
Shang M, Song H, Liu X and Tang Z. Detection and quantitation of PS20, a phosphorothioate oligodeoxynucleotides in monkey plasma. Acta Pharmacologica Sinica 2004; 25: 801-806.
-
(2004)
Acta Pharmacologica Sinica
, vol.25
, pp. 801-806
-
-
Shang, M.1
Song, H.2
Liu, X.3
Tang, Z.4
-
52
-
-
84996098737
-
On the reptation theory of gel electrophoresis
-
Slater GW and Noolandi J, On the reptation theory of gel electrophoresis. Biopolymers 1986; 25: 431-454.
-
(1986)
Biopolymers
, vol.25
, pp. 431-454
-
-
Slater, G.W.1
Noolandi, J.2
-
53
-
-
0034777744
-
Separation of double-stranded DNA fragments by capillary electrophoresis in interpenetrating networks of polyacrylamide and polyvinylpyrrolidone
-
Song L, Liu T, Liang D, Fang D and Chu B. Separation of double-stranded DNA fragments by capillary electrophoresis in interpenetrating networks of polyacrylamide and polyvinylpyrrolidone. Electrophoresis 2001; 22: 3688-3698.
-
(2001)
Electrophoresis
, vol.22
, pp. 3688-3698
-
-
Song, L.1
Liu, T.2
Liang, D.3
Fang, D.4
Chu, B.5
-
54
-
-
33645912056
-
Maternal and fetal disposition of a phosphorothioate oligonucleotide in rats following intravenous infusion
-
Soucy NV, Templin MV, Geary RS, de Peyster A and Levin A. Maternal and fetal disposition of a phosphorothioate oligonucleotide in rats following intravenous infusion. Birth Defects Research, Part B: Developmental and Reproductive Technology 2006; 77: 22-28.
-
(2006)
Birth Defects Research, Part B: Developmental and Reproductive Technology
, vol.77
, pp. 22-28
-
-
Soucy, N.V.1
Templin, M.V.2
Geary, R.S.3
de Peyster, A.4
Levin, A.5
-
55
-
-
0034721317
-
Inhibition of C-raf expression by antisense oligonucleotides extends heart allograft survival in rats
-
Stepkowski SM, Qu X, Wang ME, Tian L, Chen W, Wancewicz EV, Johnston JF, Bennett CF and Monia BP. Inhibition of C-raf expression by antisense oligonucleotides extends heart allograft survival in rats. Transplantation 2000; 70: 656-661.
-
(2000)
Transplantation
, vol.70
, pp. 656-661
-
-
Stepkowski, S.M.1
Qu, X.2
Wang, M.E.3
Tian, L.4
Chen, W.5
Wancewicz, E.V.6
Johnston, J.F.7
Bennett, C.F.8
Monia, B.P.9
-
56
-
-
69249235589
-
Capillary electrophoresis of therapeutic oligonucleotides - analysis of single- and double-stranded forms
-
Szekely L, Kiessig S, Schwarz MA and Kalman F. Capillary electrophoresis of therapeutic oligonucleotides - analysis of single- and double-stranded forms. Electrophoresis 2009; 30: 1579-1586.
-
(2009)
Electrophoresis
, vol.30
, pp. 1579-1586
-
-
Szekely, L.1
Kiessig, S.2
Schwarz, M.A.3
Kalman, F.4
-
58
-
-
0033763150
-
-
Templin MV, Levin AA, Graham MJ, Âberg PM, Axelsson BI, Butler M, Geary RS and Bennet CF. Antisense & Nucleic Acid Drug Development 2000; 10: 359-368.
-
(2000)
Antisense & Nucleic Acid Drug Development
, vol.10
, pp. 359-368
-
-
Templin, M.V.1
Levin, A.A.2
Graham, M.J.3
Âberg, P.M.4
Axelsson, B.I.5
Butler, M.6
Geary, R.S.7
Bennet, C.F.8
-
59
-
-
0030302474
-
Single-dose hemodynamic toxicity and pharmacokinetics of a partial phosphorothioate anti-HIV oligonucleotide (AR177) after intravenous infusion to cynomolgus monkeys
-
Wallace TL, Bazemore SA, Kornbrust DJ and Cossum PA. Single-dose hemodynamic toxicity and pharmacokinetics of a partial phosphorothioate anti-HIV oligonucleotide (AR177) after intravenous infusion to cynomolgus monkeys. Journal of Pharmacology and Experimental Therapy 1996; 278: 1306-1312.
-
(1996)
Journal of Pharmacology and Experimental Therapy
, vol.278
, pp. 1306-1312
-
-
Wallace, T.L.1
Bazemore, S.A.2
Kornbrust, D.J.3
Cossum, P.A.4
-
60
-
-
33646563779
-
A new quasi-interpenetrating network formed by poly(N-acryloyl-tris-(hydroxymethyl)aminomethane) and polyvinylpyrrolidone: Separation matrix for double-stranded DNA and single-stranded DNA fragments by capillary electrophoresis with UV detection
-
Wang Q, Xu X and Dai L. A new quasi-interpenetrating network formed by poly(N-acryloyl-tris-(hydroxymethyl)aminomethane) and polyvinylpyrrolidone: Separation matrix for double-stranded DNA and single-stranded DNA fragments by capillary electrophoresis with UV detection. Electrophoresis 2006; 27: 1749-1757.
-
(2006)
Electrophoresis
, vol.27
, pp. 1749-1757
-
-
Wang, Q.1
Xu, X.2
Dai, L.3
-
61
-
-
18444396632
-
Analysis of nucleic acid constituents by on-line capillary electrophoresis-mass spectrometry
-
Willems AV, Deforce DL, Van Peteghem CH and Van Bocxlaer JF. Analysis of nucleic acid constituents by on-line capillary electrophoresis-mass spectrometry. Electrophoresis 2005; 26(7-8): 1221-1253.
-
(2005)
Electrophoresis
, vol.26
, Issue.7-8
, pp. 1221-1253
-
-
Willems, A.V.1
Deforce, D.L.2
Van Peteghem, C.H.3
Van Bocxlaer, J.F.4
-
62
-
-
58349089794
-
A combined solid phase extraction/capillary gel electrophoresis method for the determination of phosphorothioate oligodeoxynucleotides in biological fluids, tissues and feces
-
Wu L, Lu D, Zhou Z, Zhang H, Zhang Y and Wang S. A combined solid phase extraction/capillary gel electrophoresis method for the determination of phosphorothioate oligodeoxynucleotides in biological fluids, tissues and feces. Journal of Chromatography B 2009; 877: 361-368.
-
(2009)
Journal of Chromatography B
, vol.877
, pp. 361-368
-
-
Wu, L.1
Lu, D.2
Zhou, Z.3
Zhang, H.4
Zhang, Y.5
Wang, S.6
-
63
-
-
0035138215
-
Comparison of pharmacokinetics and tissue disposition of an antisense phosphorothioate oligonucleotide targeting human Ha-ras mRNA in mouse and monkey
-
Yu RZ, Geary RS, Leeds JM, Watanabe T, Moore M, Fitchett J, Matson J, Burckin T, Templin MV and Levin AA. Comparison of pharmacokinetics and tissue disposition of an antisense phosphorothioate oligonucleotide targeting human Ha-ras mRNA in mouse and monkey. Journal of Pharmaceutical Science 2001; 90: 182-193.
-
(2001)
Journal of Pharmaceutical Science
, vol.90
, pp. 182-193
-
-
Yu, R.Z.1
Geary, R.S.2
Leeds, J.M.3
Watanabe, T.4
Moore, M.5
Fitchett, J.6
Matson, J.7
Burckin, T.8
Templin, M.V.9
Levin, A.A.10
-
64
-
-
0347124829
-
Tissue disposition of a 2′-O-(2-methoxy) ethyl modified antisense oligonucleotides in monkeys
-
Yu RZ, Geary RS, Monteith DK, Matson J, Truong L, Fitchett J and Levin AA. Tissue disposition of a 2′-O-(2-methoxy) ethyl modified antisense oligonucleotides in monkeys. Journal of Pharmaceutical Science 2004; 93: 48-59.
-
(2004)
Journal of Pharmaceutical Science
, vol.93
, pp. 48-59
-
-
Yu, R.Z.1
Geary, R.S.2
Monteith, D.K.3
Matson, J.4
Truong, L.5
Fitchett, J.6
Levin, A.A.7
-
65
-
-
29244491632
-
Fast separation of single-stranded oligonucleotides by capillary electrophoresis using OliGreen® as fluorescence inducing agent
-
Zhang J, Liang D, He W, Wan F, Ying Q and Chu B. Fast separation of single-stranded oligonucleotides by capillary electrophoresis using OliGreen® as fluorescence inducing agent. Eletrophoresis 2005; 26: 4449-4455.
-
(2005)
Eletrophoresis
, vol.26
, pp. 4449-4455
-
-
Zhang, J.1
Liang, D.2
He, W.3
Wan, F.4
Ying, Q.5
Chu, B.6
|