메뉴 건너뛰기




Volumn 136, Issue 1-3, 2012, Pages 82-87

α7 neuronal nicotinic receptor agonist (TC-7020) reverses increased striatal dopamine release during acoustic PPI testing in a transgenic mouse model of schizophrenia

Author keywords

FGF receptor 1; In vivo microdialysis; Midbrain dopamine neurons; Nicotinic acetylcholine receptors; Sensory gating

Indexed keywords

DOPAMINE; FIBROBLAST GROWTH FACTOR 1; NICOTINIC AGENT; TC 7020; UNCLASSIFIED DRUG;

EID: 84857994610     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2012.01.005     Document Type: Article
Times cited : (21)

References (59)
  • 3
    • 0027380988 scopus 로고
    • Normalization of auditory physiology by cigarette smoking in schizophrenic patients
    • Adler L.E., Hoffer L.D., Wiser A., Freedman R. Normalization of auditory physiology by cigarette smoking in schizophrenic patients. Am. J. Psychiatry 1993, 150(12):1856-1861.
    • (1993) Am. J. Psychiatry , vol.150 , Issue.12 , pp. 1856-1861
    • Adler, L.E.1    Hoffer, L.D.2    Wiser, A.3    Freedman, R.4
  • 4
    • 0032908295 scopus 로고    scopus 로고
    • Symptom correlates of prepulse inhibition deficits in male schizophrenic patients
    • Braff D.L., Swerdlow N.R., Geyer M.A. Symptom correlates of prepulse inhibition deficits in male schizophrenic patients. Am. J. Psychiatry 1999, 156(4):596-602.
    • (1999) Am. J. Psychiatry , vol.156 , Issue.4 , pp. 596-602
    • Braff, D.L.1    Swerdlow, N.R.2    Geyer, M.A.3
  • 6
    • 77952288419 scopus 로고    scopus 로고
    • In vivo modulation of alpha7 nicotinic receptors on striatal glutamate release induced by anatoxin-A
    • Campos F., Alfonso M., Duran R. In vivo modulation of alpha7 nicotinic receptors on striatal glutamate release induced by anatoxin-A. Neurochem. Int. 2010, 56(6-7):850-855.
    • (2010) Neurochem. Int. , vol.56 , Issue.6-7 , pp. 850-855
    • Campos, F.1    Alfonso, M.2    Duran, R.3
  • 8
    • 79960280144 scopus 로고    scopus 로고
    • Dopaminergic control of the striatum for high-level cognition
    • Cools R. Dopaminergic control of the striatum for high-level cognition. Curr. Opin. Neurobiol. 2011, 21(3):402-407.
    • (2011) Curr. Opin. Neurobiol. , vol.21 , Issue.3 , pp. 402-407
    • Cools, R.1
  • 9
    • 0017640422 scopus 로고
    • Plasticity of the acoustic startle response in the acutely decerebrate rat
    • Davis M., Gendelman P.M. Plasticity of the acoustic startle response in the acutely decerebrate rat. J. Comp. Physiol. Psychol. 1977, 91(3):549-563.
    • (1977) J. Comp. Physiol. Psychol. , vol.91 , Issue.3 , pp. 549-563
    • Davis, M.1    Gendelman, P.M.2
  • 10
    • 0030778859 scopus 로고    scopus 로고
    • The effects of stress on central dopaminergic neurons: possible clinical implications
    • Finlay J.M., Zigmond M.J. The effects of stress on central dopaminergic neurons: possible clinical implications. Neurochem. Res. 1997, 22(11):1387-1394.
    • (1997) Neurochem. Res. , vol.22 , Issue.11 , pp. 1387-1394
    • Finlay, J.M.1    Zigmond, M.J.2
  • 11
    • 0034351614 scopus 로고    scopus 로고
    • The alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia
    • Freedman R., Adams C.E., Leonard S. The alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia. J. Chem. Neuroanat. 2000, 20(3-4):299-306.
    • (2000) J. Chem. Neuroanat. , vol.20 , Issue.3-4 , pp. 299-306
    • Freedman, R.1    Adams, C.E.2    Leonard, S.3
  • 12
    • 33749071175 scopus 로고    scopus 로고
    • A preliminary study of the effects of cigarette smoking on prepulse inhibition in schizophrenia: involvement of nicotinic receptor mechanisms
    • George T.P., Termine A., Sacco K.A., Allen T.M., Reutenauer E., Vessicchio J.C., Duncan E.J. A preliminary study of the effects of cigarette smoking on prepulse inhibition in schizophrenia: involvement of nicotinic receptor mechanisms. Schizophr. Res. 2006, 87(1-3):307-315.
    • (2006) Schizophr. Res. , vol.87 , Issue.1-3 , pp. 307-315
    • George, T.P.1    Termine, A.2    Sacco, K.A.3    Allen, T.M.4    Reutenauer, E.5    Vessicchio, J.C.6    Duncan, E.J.7
  • 13
    • 0036929065 scopus 로고    scopus 로고
    • Mouse genetic models for prepulse inhibition: an early review
    • Geyer M.A., McIlwain K.L., Paylor R. Mouse genetic models for prepulse inhibition: an early review. Mol. Psychiatry 2002, 7(10):1039-1053.
    • (2002) Mol. Psychiatry , vol.7 , Issue.10 , pp. 1039-1053
    • Geyer, M.A.1    McIlwain, K.L.2    Paylor, R.3
  • 14
    • 34948819210 scopus 로고    scopus 로고
    • The Yin and Yang of dopamine release: a new perspective
    • Goto Y., Otani S., Grace A.A. The Yin and Yang of dopamine release: a new perspective. Neuropharmacology 2007, 53(5):583-587.
    • (2007) Neuropharmacology , vol.53 , Issue.5 , pp. 583-587
    • Goto, Y.1    Otani, S.2    Grace, A.A.3
  • 16
    • 61349116180 scopus 로고    scopus 로고
    • The role of the basal ganglia in learning and memory: neuropsychological studies
    • Grahn J.A., Parkinson J.A., Owen A.M. The role of the basal ganglia in learning and memory: neuropsychological studies. Behav. Brain Res. 2009, 199(1):53-60.
    • (2009) Behav. Brain Res. , vol.199 , Issue.1 , pp. 53-60
    • Grahn, J.A.1    Parkinson, J.A.2    Owen, A.M.3
  • 17
    • 0033519564 scopus 로고    scopus 로고
    • Decreased protein level of nicotinic receptor alpha7 subunit in the frontal cortex from schizophrenic brain
    • Guan Z.Z., Zhang X., Blennow K., Nordberg A. Decreased protein level of nicotinic receptor alpha7 subunit in the frontal cortex from schizophrenic brain. Neuroreport 1999, 10(8):1779-1782.
    • (1999) Neuroreport , vol.10 , Issue.8 , pp. 1779-1782
    • Guan, Z.Z.1    Zhang, X.2    Blennow, K.3    Nordberg, A.4
  • 18
    • 14344251489 scopus 로고    scopus 로고
    • The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats
    • Hajos M., Hurst R.S., Hoffmann W.E., Krause M., Wall T.M., Higdon N.R., Groppi V.E. The selective alpha7 nicotinic acetylcholine receptor agonist PNU-282987 [N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]-4-chlorobenzamide hydrochloride] enhances GABAergic synaptic activity in brain slices and restores auditory gating deficits in anesthetized rats. J. Pharmacol. Exp. Ther. 2005, 312(3):1213-1222.
    • (2005) J. Pharmacol. Exp. Ther. , vol.312 , Issue.3 , pp. 1213-1222
    • Hajos, M.1    Hurst, R.S.2    Hoffmann, W.E.3    Krause, M.4    Wall, T.M.5    Higdon, N.R.6    Groppi, V.E.7
  • 20
    • 18144437704 scopus 로고    scopus 로고
    • Effects of activation of NMDA and AMPA glutamate receptors on the extracellular concentrations of dopamine, acetylcholine, and GABA in striatum of the awake rat: a microdialysis study
    • Hernandez L.F., Segovia G., Mora F. Effects of activation of NMDA and AMPA glutamate receptors on the extracellular concentrations of dopamine, acetylcholine, and GABA in striatum of the awake rat: a microdialysis study. Neurochem. Res. 2003, 28(12):1819-1827.
    • (2003) Neurochem. Res. , vol.28 , Issue.12 , pp. 1819-1827
    • Hernandez, L.F.1    Segovia, G.2    Mora, F.3
  • 21
    • 47249146012 scopus 로고    scopus 로고
    • Nicotine effect on prepulse inhibition and prepulse facilitation in schizophrenia patients
    • Hong L.E., Wonodi I., Lewis J., Thaker G.K. Nicotine effect on prepulse inhibition and prepulse facilitation in schizophrenia patients. Neuropsychopharmacology 2008, 33(9):2167-2174.
    • (2008) Neuropsychopharmacology , vol.33 , Issue.9 , pp. 2167-2174
    • Hong, L.E.1    Wonodi, I.2    Lewis, J.3    Thaker, G.K.4
  • 22
    • 10644254858 scopus 로고    scopus 로고
    • Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area
    • Jones I.W., Wonnacott S. Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area. J. Neurosci. 2004, 24(50):11244-11252.
    • (2004) J. Neurosci. , vol.24 , Issue.50 , pp. 11244-11252
    • Jones, I.W.1    Wonnacott, S.2
  • 23
    • 0033930973 scopus 로고    scopus 로고
    • Alpha-bungarotoxin-sensitive nicotinic receptors indirectly modulate [(3)H]dopamine release in rat striatal slices via glutamate release
    • Kaiser S., Wonnacott S. Alpha-bungarotoxin-sensitive nicotinic receptors indirectly modulate [(3)H]dopamine release in rat striatal slices via glutamate release. Mol. Pharmacol. 2000, 58(2):312-318.
    • (2000) Mol. Pharmacol. , vol.58 , Issue.2 , pp. 312-318
    • Kaiser, S.1    Wonnacott, S.2
  • 24
    • 34848823229 scopus 로고    scopus 로고
    • Schizophrenia is associated with increased synaptic dopamine in associative rather than limbic regions of the striatum: implications for mechanisms of action of antipsychotic drugs
    • Kegeles L.S., Frankle W.G., Gil R., Narendran R., Slifstein M., Hwang D.R., Cangiano C., Haber S.N., Abi-Dargham A., Laruelle M. Schizophrenia is associated with increased synaptic dopamine in associative rather than limbic regions of the striatum: implications for mechanisms of action of antipsychotic drugs. J. Nucl. Med. 2006, 47:139.
    • (2006) J. Nucl. Med. , vol.47 , pp. 139
    • Kegeles, L.S.1    Frankle, W.G.2    Gil, R.3    Narendran, R.4    Slifstein, M.5    Hwang, D.R.6    Cangiano, C.7    Haber, S.N.8    Abi-Dargham, A.9    Laruelle, M.10
  • 25
    • 33646582305 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor signaling affects development and function of dopamine neurons - inhibition results in a schizophrenia-like syndrome in transgenic mice
    • Klejbor I., Myers J.M., Hausknecht K., Corso T.D., Gambino A.S., Morys J., Maher P.A., Hard R., Richards J., Stachowiak E.K., Stachowiak M.K. Fibroblast growth factor receptor signaling affects development and function of dopamine neurons - inhibition results in a schizophrenia-like syndrome in transgenic mice. J. Neurochem. 2006, 97(5):1243-1258.
    • (2006) J. Neurochem. , vol.97 , Issue.5 , pp. 1243-1258
    • Klejbor, I.1    Myers, J.M.2    Hausknecht, K.3    Corso, T.D.4    Gambino, A.S.5    Morys, J.6    Maher, P.A.7    Hard, R.8    Richards, J.9    Stachowiak, E.K.10    Stachowiak, M.K.11
  • 27
    • 77956366630 scopus 로고    scopus 로고
    • Ameliorating effects of tropisetron on dopaminergic disruption of prepulse inhibition via the alpha(7) nicotinic acetylcholine receptor in Wistar rats
    • Kohnomi S., Suemaru K., Goda M., Choshi T., Hibino S., Kawasaki H., Araki H. Ameliorating effects of tropisetron on dopaminergic disruption of prepulse inhibition via the alpha(7) nicotinic acetylcholine receptor in Wistar rats. Brain Res. 2010, 1353:152-158.
    • (2010) Brain Res. , vol.1353 , pp. 152-158
    • Kohnomi, S.1    Suemaru, K.2    Goda, M.3    Choshi, T.4    Hibino, S.5    Kawasaki, H.6    Araki, H.7
  • 28
    • 56349143278 scopus 로고    scopus 로고
    • Striatal plasticity and basal ganglia circuit function
    • Kreitzer A.C., Malenka R.C. Striatal plasticity and basal ganglia circuit function. Neuron 2008, 60(4):543-554.
    • (2008) Neuron , vol.60 , Issue.4 , pp. 543-554
    • Kreitzer, A.C.1    Malenka, R.C.2
  • 29
    • 79551673655 scopus 로고    scopus 로고
    • Alpha7 neuronal nicotinic receptors as targets for novel therapies to treat multiple domains of schizophrenia
    • Kucinski A.J., Stachowiak M.K., Wersinger S.R., Lippiello P.M., Bencherif M. Alpha7 neuronal nicotinic receptors as targets for novel therapies to treat multiple domains of schizophrenia. Curr. Pharm. Biotechnol. 2011, 12(3):437-448.
    • (2011) Curr. Pharm. Biotechnol. , vol.12 , Issue.3 , pp. 437-448
    • Kucinski, A.J.1    Stachowiak, M.K.2    Wersinger, S.R.3    Lippiello, P.M.4    Bencherif, M.5
  • 31
    • 0032987267 scopus 로고    scopus 로고
    • Increased dopamine transmission in schizophrenia: relationship to illness phases
    • Laruelle M., Abi-Dargham A., Gil R., Kegeles L., Innis R. Increased dopamine transmission in schizophrenia: relationship to illness phases. Biol. Psychiatry 1999, 46(1):56-72.
    • (1999) Biol. Psychiatry , vol.46 , Issue.1 , pp. 56-72
    • Laruelle, M.1    Abi-Dargham, A.2    Gil, R.3    Kegeles, L.4    Innis, R.5
  • 33
    • 36448982527 scopus 로고    scopus 로고
    • Smoking, genetics and schizophrenia: evidence for self medication
    • Leonard S., Mexal S., Freedman R. Smoking, genetics and schizophrenia: evidence for self medication. J. Dual. Diagn. 2007, 3(3-4):43-59.
    • (2007) J. Dual. Diagn. , vol.3 , Issue.3-4 , pp. 43-59
    • Leonard, S.1    Mexal, S.2    Freedman, R.3
  • 34
    • 33749645423 scopus 로고    scopus 로고
    • Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations
    • Lewis D.A., Moghaddam B. Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations. Arch. Neurol. 2006, 63(10):1372-1376.
    • (2006) Arch. Neurol. , vol.63 , Issue.10 , pp. 1372-1376
    • Lewis, D.A.1    Moghaddam, B.2
  • 35
    • 42749095376 scopus 로고    scopus 로고
    • Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
    • Lisman J.E., Coyle J.T., Green R.W., Javitt D.C., Benes F.M., Heckers S., Grace A.A. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci. 2008, 31(5):234-242.
    • (2008) Trends Neurosci. , vol.31 , Issue.5 , pp. 234-242
    • Lisman, J.E.1    Coyle, J.T.2    Green, R.W.3    Javitt, D.C.4    Benes, F.M.5    Heckers, S.6    Grace, A.A.7
  • 36
    • 0023870896 scopus 로고
    • Dopaminergic stimulation disrupts sensorimotor gating in the rat
    • Mansbach R.S., Geyer M.A., Braff D.L. Dopaminergic stimulation disrupts sensorimotor gating in the rat. Psychopharmacology (Berl) 1988, 94(4):507-514.
    • (1988) Psychopharmacology (Berl) , vol.94 , Issue.4 , pp. 507-514
    • Mansbach, R.S.1    Geyer, M.A.2    Braff, D.L.3
  • 37
    • 77149138329 scopus 로고    scopus 로고
    • Glutamatergic (N-methyl-d-aspartate receptor) hypofrontality in schizophrenia: too little juice or a miswired brain?
    • Marek G.J., Behl B., Bespalov A.Y., Gross G., Lee Y., Schoemaker H. Glutamatergic (N-methyl-d-aspartate receptor) hypofrontality in schizophrenia: too little juice or a miswired brain?. Mol. Pharmacol. 2010, 77(3):317-326.
    • (2010) Mol. Pharmacol. , vol.77 , Issue.3 , pp. 317-326
    • Marek, G.J.1    Behl, B.2    Bespalov, A.Y.3    Gross, G.4    Lee, Y.5    Schoemaker, H.6
  • 38
    • 73949111377 scopus 로고    scopus 로고
    • An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes
    • Marrero M.B., Lucas R., Salet C., Hauser T.A., Mazurov A., Lippiello P.M., Bencherif M. An alpha7 nicotinic acetylcholine receptor-selective agonist reduces weight gain and metabolic changes in a mouse model of diabetes. J. Pharmacol. Exp. Ther. 2010, 332(1):173-180.
    • (2010) J. Pharmacol. Exp. Ther. , vol.332 , Issue.1 , pp. 173-180
    • Marrero, M.B.1    Lucas, R.2    Salet, C.3    Hauser, T.A.4    Mazurov, A.5    Lippiello, P.M.6    Bencherif, M.7
  • 39
    • 33847351996 scopus 로고    scopus 로고
    • Schizophrenia and the alpha7 nicotinic acetylcholine receptor
    • Martin L.F., Freedman R. Schizophrenia and the alpha7 nicotinic acetylcholine receptor. Int. Rev. Neurobiol. 2007, 78:225-246.
    • (2007) Int. Rev. Neurobiol. , vol.78 , pp. 225-246
    • Martin, L.F.1    Freedman, R.2
  • 40
    • 3142761435 scopus 로고    scopus 로고
    • Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia
    • Martin L.F., Kem W.R., Freedman R. Alpha-7 nicotinic receptor agonists: potential new candidates for the treatment of schizophrenia. Psychopharmacology (Berl) 2004, 174(1):54-64.
    • (2004) Psychopharmacology (Berl) , vol.174 , Issue.1 , pp. 54-64
    • Martin, L.F.1    Kem, W.R.2    Freedman, R.3
  • 43
    • 0028850552 scopus 로고
    • Glutamate receptor dysfunction and schizophrenia
    • Olney J.W., Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch. Gen. Psychiatry 1995, 52(12):998-1007.
    • (1995) Arch. Gen. Psychiatry , vol.52 , Issue.12 , pp. 998-1007
    • Olney, J.W.1    Farber, N.B.2
  • 44
    • 69249214145 scopus 로고    scopus 로고
    • Prepulse inhibition and genetic mouse models of schizophrenia
    • Powell S.B., Zhou X., Geyer M.A. Prepulse inhibition and genetic mouse models of schizophrenia. Behav. Brain. Res. 2009, 204(2):282-294.
    • (2009) Behav. Brain. Res. , vol.204 , Issue.2 , pp. 282-294
    • Powell, S.B.1    Zhou, X.2    Geyer, M.A.3
  • 45
    • 0035143189 scopus 로고    scopus 로고
    • Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists
    • Ralph R.J., Paulus M.P., Fumagalli F., Caron M.G., Geyer M.A. Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: differential effects of D1 and D2 receptor antagonists. J. Neurosci. 2001, 21(1):305-313.
    • (2001) J. Neurosci. , vol.21 , Issue.1 , pp. 305-313
    • Ralph, R.J.1    Paulus, M.P.2    Fumagalli, F.3    Caron, M.G.4    Geyer, M.A.5
  • 46
  • 47
    • 2442653986 scopus 로고    scopus 로고
    • Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice
    • Salminen O., Murphy K.L., McIntosh J.M., Drago J., Marks M.J., Collins A.C., Grady S.R. Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice. Mol. Pharmacol. 2004, 65(6):1526-1535.
    • (2004) Mol. Pharmacol. , vol.65 , Issue.6 , pp. 1526-1535
    • Salminen, O.1    Murphy, K.L.2    McIntosh, J.M.3    Drago, J.4    Marks, M.J.5    Collins, A.C.6    Grady, S.R.7
  • 48
    • 0030886439 scopus 로고    scopus 로고
    • Endogenous glutamate increases extracellular concentrations of dopamine, GABA, and taurine through NMDA and AMPA/kainate receptors in striatum of the freely moving rat: a microdialysis study
    • Segovia G., Del Arco A., Mora F. Endogenous glutamate increases extracellular concentrations of dopamine, GABA, and taurine through NMDA and AMPA/kainate receptors in striatum of the freely moving rat: a microdialysis study. J. Neurochem. 1997, 69(4):1476-1483.
    • (1997) J. Neurochem. , vol.69 , Issue.4 , pp. 1476-1483
    • Segovia, G.1    Del Arco, A.2    Mora, F.3
  • 49
    • 72049085285 scopus 로고    scopus 로고
    • Cortico-basal ganglia reward network: microcircuitry
    • Sesack S.R., Grace A.A. Cortico-basal ganglia reward network: microcircuitry. Neuropsychopharmacology 2010, 35(1):27-47.
    • (2010) Neuropsychopharmacology , vol.35 , Issue.1 , pp. 27-47
    • Sesack, S.R.1    Grace, A.A.2
  • 50
    • 77649092400 scopus 로고    scopus 로고
    • A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia
    • Simpson E.H., Kellendonk C., Kandel E. A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia. Neuron 2010, 65(5):585-596.
    • (2010) Neuron , vol.65 , Issue.5 , pp. 585-596
    • Simpson, E.H.1    Kellendonk, C.2    Kandel, E.3
  • 51
    • 3242889661 scopus 로고    scopus 로고
    • Nicotine blocks apomorphine-induced disruption of prepulse inhibition of the acoustic startle in rats: possible involvement of central nicotinic alpha7 receptors
    • Suemaru K., Yasuda K., Umeda K., Araki H., Shibata K., Choshi T., Hibino S., Gomita Y. Nicotine blocks apomorphine-induced disruption of prepulse inhibition of the acoustic startle in rats: possible involvement of central nicotinic alpha7 receptors. Br. J. Pharmacol. 2004, 142(5):843-850.
    • (2004) Br. J. Pharmacol. , vol.142 , Issue.5 , pp. 843-850
    • Suemaru, K.1    Yasuda, K.2    Umeda, K.3    Araki, H.4    Shibata, K.5    Choshi, T.6    Hibino, S.7    Gomita, Y.8
  • 52
    • 0031720755 scopus 로고    scopus 로고
    • Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia
    • Swerdlow N.R., Geyer M.A. Using an animal model of deficient sensorimotor gating to study the pathophysiology and new treatments of schizophrenia. Schizophr. Bull. 1998, 24(2):285-301.
    • (1998) Schizophr. Bull. , vol.24 , Issue.2 , pp. 285-301
    • Swerdlow, N.R.1    Geyer, M.A.2
  • 53
    • 0031736368 scopus 로고    scopus 로고
    • Towards a cross-species pharmacology of sensorimotor gating: effects of amantadine, bromocriptine, pergolide and ropinirole on prepulse inhibition of acoustic startle in rats
    • Swerdlow N.R., Taaid N., Oostwegel J.L., Randolph E., Geyer M.A. Towards a cross-species pharmacology of sensorimotor gating: effects of amantadine, bromocriptine, pergolide and ropinirole on prepulse inhibition of acoustic startle in rats. Behav. Pharmacol. 1998, 9(5-6):389-396.
    • (1998) Behav. Pharmacol. , vol.9 , Issue.5-6 , pp. 389-396
    • Swerdlow, N.R.1    Taaid, N.2    Oostwegel, J.L.3    Randolph, E.4    Geyer, M.A.5
  • 54
    • 77949462775 scopus 로고    scopus 로고
    • Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: from animal models to human pathophysiology
    • Thomsen M.S., Hansen H.H., Timmerman D.B., Mikkelsen J.D. Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: from animal models to human pathophysiology. Curr. Pharm. Des. 2010, 16(3):323-343.
    • (2010) Curr. Pharm. Des. , vol.16 , Issue.3 , pp. 323-343
    • Thomsen, M.S.1    Hansen, H.H.2    Timmerman, D.B.3    Mikkelsen, J.D.4
  • 56
    • 77749279516 scopus 로고    scopus 로고
    • Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects
    • van den Buuse M. Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspects. Schizophr. Bull. 2010, 36(2):246-270.
    • (2010) Schizophr. Bull. , vol.36 , Issue.2 , pp. 246-270
    • van den Buuse, M.1
  • 58
    • 0029150024 scopus 로고
    • Presynaptic dopamine-glutamate interactions in the nucleus accumbens regulate sensorimotor gating
    • Wan F.J., Geyer M.A., Swerdlow N.R. Presynaptic dopamine-glutamate interactions in the nucleus accumbens regulate sensorimotor gating. Psychopharmacology (Berl) 1995, 120(4):433-441.
    • (1995) Psychopharmacology (Berl) , vol.120 , Issue.4 , pp. 433-441
    • Wan, F.J.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 59
    • 0037870490 scopus 로고    scopus 로고
    • Schizophrenia: from phenomenology to neurobiology
    • Wong A.H., Van Tol H.H. Schizophrenia: from phenomenology to neurobiology. Neurosci. Biobehav. Rev. 2003, 27(3):269-306.
    • (2003) Neurosci. Biobehav. Rev. , vol.27 , Issue.3 , pp. 269-306
    • Wong, A.H.1    Van Tol, H.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.