-
1
-
-
0033057326
-
Pharmacologic management of Alzheimer disease, Part II: Antioxidants, antihypertensives, and ergoloid derivatives
-
Flynn BL, Ranno AE. Pharmacologic management of Alzheimer disease, Part II: Antioxidants, antihypertensives, and ergoloid derivatives. Ann Pharmacother 1999; 33:188-197.
-
(1999)
Ann Pharmacother
, vol.33
, pp. 188-197
-
-
Flynn, B.L.1
Ranno, A.E.2
-
2
-
-
84862833134
-
Scavenging effect of Naoerkang () on amyloid betapeptide deposition in the hippocampus in a rat model of Alzheimer's disease
-
Li X, Yuan HF, Quan QK, Wang JJ, Wang NN, Li M. Scavenging effect of Naoerkang () on amyloid betapeptide deposition in the hippocampus in a rat model of Alzheimer's disease. Chin J Integr Med 2011; 17(11):847-53.
-
(2011)
Chin J Integr Med
, vol.17
, Issue.11
, pp. 847-853
-
-
Li, X.1
Yuan, H.F.2
Quan, Q.K.3
Wang, J.J.4
Wang, N.N.5
Li, M.6
-
3
-
-
59749101914
-
Environmental enrichment enhances cellular plasticity in transgenic mice with Alzheimer-like pathology
-
Herring A, Ambrée O, Tomm M, Habermann H, Sachser N, Paulus W, et al. Environmental enrichment enhances cellular plasticity in transgenic mice with Alzheimer-like pathology. Exp Neurol 2009; 216:184-192.
-
(2009)
Exp Neurol
, vol.216
, pp. 184-192
-
-
Herring, A.1
Ambrée, O.2
Tomm, M.3
Habermann, H.4
Sachser, N.5
Paulus, W.6
-
4
-
-
60749093075
-
Engineered antibody intervention strategies for Alzheimer's disease and related dementias by targeting amyloid and toxic oligomers
-
Robert R, Dolezal O, Waddington L, Hattarki MK, Cappai R, Masters CL, et al. Engineered antibody intervention strategies for Alzheimer's disease and related dementias by targeting amyloid and toxic oligomers. Protein Eng Des Sel 2009; 22:199-208.
-
(2009)
Protein Eng Des Sel
, vol.22
, pp. 199-208
-
-
Robert, R.1
Dolezal, O.2
Waddington, L.3
Hattarki, M.K.4
Cappai, R.5
Masters, C.L.6
-
5
-
-
33947262557
-
Soluble beta-amyloid [25-35] reversibly impairs hippocampal synaptic plasticity and spatial learning
-
Holscher C, Gengler S, Gault VA, Harriott P, Mallot HA. Soluble beta-amyloid [25-35] reversibly impairs hippocampal synaptic plasticity and spatial learning. Eur J Pharmacol 2007; 561:85-90.
-
(2007)
Eur J Pharmacol
, vol.561
, pp. 85-90
-
-
Holscher, C.1
Gengler, S.2
Gault, V.A.3
Harriott, P.4
Mallot, H.A.5
-
6
-
-
0035910306
-
Intracerebroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment
-
Sharma M, Gupta YK. Intracerebroventricular injection of streptozotocin in rats produces both oxidative stress in the brain and cognitive impairment. Life Sci 2001; 68:1021-1029.
-
(2001)
Life Sci
, vol.68
, pp. 1021-1029
-
-
Sharma, M.1
Gupta, Y.K.2
-
7
-
-
0035857738
-
Protein oxidation in the brain in Alzheimer's disease
-
Aksenov MY, Aksenova MV, Butterfield DA, Geddes JW, Markesbery WR. Protein oxidation in the brain in Alzheimer's disease. Neuroscience 2001; 103:373-383.
-
(2001)
Neuroscience
, vol.103
, pp. 373-383
-
-
Aksenov, M.Y.1
Aksenova, M.V.2
Butterfield, D.A.3
Geddes, J.W.4
Markesbery, W.R.5
-
8
-
-
0028792111
-
Lipid peroxidation and antioxidants as biomarkers of tissue damage
-
Gutteridge JM. Lipid peroxidation and antioxidants as biomarkers of tissue damage. Clin Chem 1995; 41:1819-1828.
-
(1995)
Clin Chem
, vol.41
, pp. 1819-1828
-
-
Gutteridge, J.M.1
-
9
-
-
33646596554
-
Coenzyme Q10 modulates cognitive impairment against intracerebroventricular injection of streptozotocin in rats
-
Ishrat T, Khan MB, Hoda MN, Yousuf S, Ahmad M, Ansari MA, et al. Coenzyme Q10 modulates cognitive impairment against intracerebroventricular injection of streptozotocin in rats. Behav Brain Res 2006; 171:9-16.
-
(2006)
Behav Brain Res
, vol.171
, pp. 9-16
-
-
Ishrat, T.1
Khan, M.B.2
Hoda, M.N.3
Yousuf, S.4
Ahmad, M.5
Ansari, M.A.6
-
10
-
-
67649435873
-
Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type
-
Ishrat T, Parveen K, Khan MM, Khuwaja G, Khan MB, Yousuf S, et al. Selenium prevents cognitive decline and oxidative damage in rat model of streptozotocin-induced experimental dementia of Alzheimer's type. Brain Res 2009; 1281:117-127.
-
(2009)
Brain Res
, vol.1281
, pp. 117-127
-
-
Ishrat, T.1
Parveen, K.2
Khan, M.M.3
Khuwaja, G.4
Khan, M.B.5
Yousuf, S.6
-
11
-
-
0029042393
-
Biochemical, physiological and medical aspects of ubiquinone function
-
Ernster L, Dallner G. Biochemical, physiological and medical aspects of ubiquinone function. Biochim Biophys Acta 1995; 1271:195-204.
-
(1995)
Biochim Biophys Acta
, vol.1271
, pp. 195-204
-
-
Ernster, L.1
Dallner, G.2
-
12
-
-
34249008430
-
Coenzyme Q10 prevents high glucose-induced oxidative stress in human umbilical vein endothelial cells
-
Tsuneki H, Sekizaki N, Suzuki T, Kobayashi S, Wada T, Okamoto T, et al. Coenzyme Q10 prevents high glucose-induced oxidative stress in human umbilical vein endothelial cells. Eur J Pharmacol 2007; 566:1-10.
-
(2007)
Eur J Pharmacol
, vol.566
, pp. 1-10
-
-
Tsuneki, H.1
Sekizaki, N.2
Suzuki, T.3
Kobayashi, S.4
Wada, T.5
Okamoto, T.6
-
13
-
-
13844298846
-
Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice
-
McDonald SR, Sohal RS, Forster MJ. Concurrent administration of coenzyme Q10 and alpha-tocopherol improves learning in aged mice. Free Radic Biol Med 2005; 38:729-736.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 729-736
-
-
McDonald, S.R.1
Sohal, R.S.2
Forster, M.J.3
-
14
-
-
0032522304
-
Electron transport-linked ubiquinone-dependent recycling of alpha-tocopherol inhibits autooxidation of mitochondrial membranes
-
Lass A, Sohal RS. Electron transport-linked ubiquinone-dependent recycling of alpha-tocopherol inhibits autooxidation of mitochondrial membranes. Arch Biochem Biophys 1998; 352:229-236.
-
(1998)
Arch Biochem Biophys
, vol.352
, pp. 229-236
-
-
Lass, A.1
Sohal, R.S.2
-
15
-
-
80155191237
-
Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of Alzheimer's disease
-
Dumont M, Kipiani K, Yu F, Wille E, Katz M, Calingasan NY, et al. Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of Alzheimer's disease. J Alzheimers Dis 2011; 27:211-223.
-
(2011)
J Alzheimers Dis
, vol.27
, pp. 211-223
-
-
Dumont, M.1
Kipiani, K.2
Yu, F.3
Wille, E.4
Katz, M.5
Calingasan, N.Y.6
-
16
-
-
80052797626
-
The role of nutraceuticals in anti-aging medicine
-
Vranesić-Bender D. The role of nutraceuticals in anti-aging medicine. Acta Clin Croat 2010; 49:537-544.
-
(2010)
Acta Clin Croat
, vol.49
, pp. 537-544
-
-
Vranesić-Bender, D.1
-
18
-
-
0030590103
-
Relevance of the biosynthesis of coenzyme Q10 and the four bases of DNA as a rationale for the molecular causes of cancer and a therapy
-
Folkers K. Relevance of the biosynthesis of coenzyme Q10 and the four bases of DNA as a rationale for the molecular causes of cancer and a therapy. Biochem Biophys Res Commun 1996; 224:358-61.
-
(1996)
Biochem Biophys Res Commun
, vol.224
, pp. 358-361
-
-
Folkers, K.1
-
19
-
-
0031442693
-
Folate and antifolate pharmacology
-
Kamen B. Folate and antifolate pharmacology. Semin Oncol 1997; 24:S18-30-S18-39.
-
(1997)
Semin Oncol
, vol.24
-
-
Kamen, B.1
-
20
-
-
0037075257
-
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
-
Seshadri S, Beiser A, Selhub J, Jacques PF, Rosenberg IH, D'Agostino RB, et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med 2002; 346:476-483.
-
(2002)
N Engl J Med
, vol.346
, pp. 476-483
-
-
Seshadri, S.1
Beiser, A.2
Selhub, J.3
Jacques, P.F.4
Rosenberg, I.H.5
D'Agostino, R.B.6
-
21
-
-
0345491996
-
Null association between prostate cancer and serum folate, vitamin B(6), vitamin B(12), and homocysteine
-
Weinstein SJ, Hartman TJ, Stolzenberg-Solomon R, Pietinen P, Barrett MJ, Taylor PR, et al. Null association between prostate cancer and serum folate, vitamin B(6), vitamin B(12), and homocysteine. Cancer Epidemiol Biomarkers Prev 2003; 12:1271-1272.
-
(2003)
Cancer Epidemiol Biomarkers Prev
, vol.12
, pp. 1271-1272
-
-
Weinstein, S.J.1
Hartman, T.J.2
Stolzenberg-Solomon, R.3
Pietinen, P.4
Barrett, M.J.5
Taylor, P.R.6
-
22
-
-
0014294012
-
Mental effects of anticonvulsants, and folic acid metabolism
-
Reynolds EH. Mental effects of anticonvulsants, and folic acid metabolism. Brain 1968; 91:197-214.
-
(1968)
Brain
, vol.91
, pp. 197-214
-
-
Reynolds, E.H.1
-
23
-
-
0035876883
-
Free radical scavenging behavior of folic acid: Evidence for possible antioxidant activity
-
Joshi R, Adhikari S, Patro BS, Chattopadhyay S, Mukherjee T. Free radical scavenging behavior of folic acid: evidence for possible antioxidant activity. Free Radic Biol Med 2001; 30:1390-1399.
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 1390-1399
-
-
Joshi, R.1
Adhikari, S.2
Patro, B.S.3
Chattopadhyay, S.4
Mukherjee, T.5
-
24
-
-
79151485351
-
Beneficial effects of folic acid on enhancement of memory and antioxidant status in aged rat brain
-
Singh R, Kanwar SS, Sood PK, Nehru B. Beneficial effects of folic acid on enhancement of memory and antioxidant status in aged rat brain. Cell Mol Neurobiol 2011; 31:83-91.
-
(2011)
Cell Mol Neurobiol
, vol.31
, pp. 83-91
-
-
Singh, R.1
Kanwar, S.S.2
Sood, P.K.3
Nehru, B.4
-
26
-
-
0031597388
-
Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease
-
Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM. Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol 1998; 55:1449-1455.
-
(1998)
Arch Neurol
, vol.55
, pp. 1449-1455
-
-
Clarke, R.1
Smith, A.D.2
Jobst, K.A.3
Refsum, H.4
Sutton, L.5
Ueland, P.M.6
-
27
-
-
70449513452
-
Increase in the oxidized/total coenzyme Q-10 ratio in the cerebrospinal fluid of Alzheimer's disease patients
-
Isobe C, Abe T, Terayama Y. Increase in the oxidized/total coenzyme Q-10 ratio in the cerebrospinal fluid of Alzheimer's disease patients. Dement Geriatr Cogn Disord 2009; 28:449-454.
-
(2009)
Dement Geriatr Cogn Disord
, vol.28
, pp. 449-454
-
-
Isobe, C.1
Abe, T.2
Terayama, Y.3
-
28
-
-
0031797937
-
Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats
-
Lannert H, Hoyer S. Intracerebroventricular administration of streptozotocin causes long-term diminutions in learning and memory abilities and in cerebral energy metabolism in adult rats. Behav Neurosci 1998; 112:1199-1208.
-
(1998)
Behav Neurosci
, vol.112
, pp. 1199-1208
-
-
Lannert, H.1
Hoyer, S.2
-
29
-
-
81155137697
-
Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model
-
Ponce-Lopez T, Liy-Salmeron G, Hong E, Meneses A. Lithium, phenserine, memantine and pioglitazone reverse memory deficit and restore phospho-GSK3β decreased in hippocampus in intracerebroventricular streptozotocin induced memory deficit model. Brain Res 2011; 1426:73-85.
-
(2011)
Brain Res
, vol.1426
, pp. 73-85
-
-
Ponce-Lopez, T.1
Liy-Salmeron, G.2
Hong, E.3
Meneses, A.4
-
31
-
-
33846924328
-
Ladostigil prevents gliosis, oxidativenitrative stress and memory deficits induced by intracerebroventricular injection of streptozotocin in rats
-
Shoham S, Bejar C, Kovalev E, Schorer-Apelbaum D, Weinstock M. Ladostigil prevents gliosis, oxidativenitrative stress and memory deficits induced by intracerebroventricular injection of streptozotocin in rats. Neuropharmacology 2007; 52:836-843.
-
(2007)
Neuropharmacology
, vol.52
, pp. 836-843
-
-
Shoham, S.1
Bejar, C.2
Kovalev, E.3
Schorer-Apelbaum, D.4
Weinstock, M.5
-
32
-
-
0028598190
-
Intracerebroventricular injection of streptozotocin induces discrete local changes in cerebral glucose utilization in rats
-
Duelli R, Schröck H, Kuschinsky W, Hoyer S. Intracerebroventricular injection of streptozotocin induces discrete local changes in cerebral glucose utilization in rats. Int J Dev Neurosci 1994; 12:737-743.
-
(1994)
Int J Dev Neurosci
, vol.12
, pp. 737-743
-
-
Duelli, R.1
Schröck, H.2
Kuschinsky, W.3
Hoyer, S.4
-
33
-
-
0025737376
-
Local action of the diabetogenic drug, streptozotocin, on glucose and energy metabolism in rat brain cortex
-
Nitsch R, Hoyer S. Local action of the diabetogenic drug, streptozotocin, on glucose and energy metabolism in rat brain cortex. Neurosci Lett 1991; 128:199-202.
-
(1991)
Neurosci Lett
, vol.128
, pp. 199-202
-
-
Nitsch, R.1
Hoyer, S.2
-
34
-
-
0027518372
-
Spatial learning deficit and reduced hippocampal ChAT activity in rats after an ICV injection of streptozotocin
-
Blokland A, Jolles J. Spatial learning deficit and reduced hippocampal ChAT activity in rats after an ICV injection of streptozotocin. Pharmacol Biochem Behav 1993; 44:491-494.
-
(1993)
Pharmacol Biochem Behav
, vol.44
, pp. 491-494
-
-
Blokland, A.1
Jolles, J.2
-
35
-
-
0033380660
-
Inhibition of the neuronal insulin receptor causes Alzheimer-like disturbances in oxidative/energy brain metabolism and in behavior in adult rats
-
Hoyer S, Lannert H. Inhibition of the neuronal insulin receptor causes Alzheimer-like disturbances in oxidative/energy brain metabolism and in behavior in adult rats. Ann N Y Acad Sci 1999; 893:301-303.
-
(1999)
Ann N Y Acad Sci
, vol.893
, pp. 301-303
-
-
Hoyer, S.1
Lannert, H.2
-
36
-
-
0030915855
-
Oxidative stress hypothesis in Alzheimer's disease
-
Markesbery WR. Oxidative stress hypothesis in Alzheimer's disease. Free Radic Biol Med 1997; 23:134-147.
-
(1997)
Free Radic Biol Med
, vol.23
, pp. 134-147
-
-
Markesbery, W.R.1
-
37
-
-
0038491473
-
Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics
-
Liu R, Liu IY, Bi X, Thompson RF, Doctrow SR, Malfroy B, et al. Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics. Proc Natl Acad Sci USA 2003; 100:8526-8531.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8526-8531
-
-
Liu, R.1
Liu, I.Y.2
Bi, X.3
Thompson, R.F.4
Doctrow, S.R.5
Malfroy, B.6
-
38
-
-
0030698871
-
Life and death of neurons in the aging brain
-
Morrison JH, Hof PR. Life and death of neurons in the aging brain. Science 1997; 278:412-419.
-
(1997)
Science
, vol.278
, pp. 412-419
-
-
Morrison, J.H.1
Hof, P.R.2
-
39
-
-
1242274617
-
Therapeutic effects of coenzyme Q10 in neurodegenerative diseases
-
Beal MF. Therapeutic effects of coenzyme Q10 in neurodegenerative diseases. Methods Enzymol 2004; 382:473-487.
-
(2004)
Methods Enzymol
, vol.382
, pp. 473-487
-
-
Beal, M.F.1
-
40
-
-
0035141065
-
Effects of coenzyme Q10 treatment on antioxidant pathways in normal and streptozotocin-induced diabetic rats
-
Rauscher FM, Sanders RA, Watkins JB. Effects of coenzyme Q10 treatment on antioxidant pathways in normal and streptozotocin-induced diabetic rats. J Biochem Mol Toxicol 2001; 15:41-46.
-
(2001)
J Biochem Mol Toxicol
, vol.15
, pp. 41-46
-
-
Rauscher, F.M.1
Sanders, R.A.2
Watkins, J.B.3
-
41
-
-
0030586972
-
Hyperhomocysteinemia induced by folic acid deficiency and methionine load--applications of a modified HPLC method
-
Durand P, Fortin LJ, Lussier-Cacan S, Davignon J, Blache D. Hyperhomocysteinemia induced by folic acid deficiency and methionine load--applications of a modified HPLC method. Clin Chim Acta 1996; 252:83-93.
-
(1996)
Clin Chim Acta
, vol.252
, pp. 83-93
-
-
Durand, P.1
Fortin, L.J.2
Lussier-Cacan, S.3
Davignon, J.4
Blache, D.5
-
42
-
-
0036484629
-
Folic acid and homocysteine in age-related disease
-
Mattson MP, Kruman II, Duan W. Folic acid and homocysteine in age-related disease. Ageing Res Rev 2002; 1:95-111.
-
(2002)
Ageing Res Rev
, vol.1
, pp. 95-111
-
-
Mattson, M.P.1
Kruman, I.I.2
Duan, W.3
-
43
-
-
0342624737
-
Homocysteine mediated endothelial cell toxicity and its amelioration
-
Blundell G, Jones BG, Rose FA, Tudball N. Homocysteine mediated endothelial cell toxicity and its amelioration. Atherosclerosis 1996; 122:163-172.
-
(1996)
Atherosclerosis
, vol.122
, pp. 163-172
-
-
Blundell, G.1
Jones, B.G.2
Rose, F.A.3
Tudball, N.4
-
44
-
-
0034666267
-
Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity
-
Kruman II, Culmsee C, Chan SL, Kruman Y, Guo Z, Penix L, et al. Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity. J Neurosci 2000; 20:6920-6926.
-
(2000)
J Neurosci
, vol.20
, pp. 6920-6926
-
-
Kruman, I.I.1
Culmsee, C.2
Chan, S.L.3
Kruman, Y.4
Guo, Z.5
Penix, L.6
-
45
-
-
79151485351
-
Beneficial effects of folic Acid on enhancement of memory and antioxidant status in aged rat brain
-
Singh R, Kanwar SS, Sood PK, Nehru B. Beneficial effects of folic Acid on enhancement of memory and antioxidant status in aged rat brain. Cell Mol Neurobiol 2011; 31:83-91.
-
(2011)
Cell Mol Neurobiol
, vol.31
, pp. 83-91
-
-
Singh, R.1
Kanwar, S.S.2
Sood, P.K.3
Nehru, B.4
-
46
-
-
0028169132
-
Oxygen free radicals and antioxidants: A review
-
Barber DA, Harris SR. Oxygen free radicals and antioxidants: a review. Am Pharm 1994; NS34:6-35.
-
(1994)
Am Pharm
, vol.NS34
, pp. 6-35
-
-
Barber, D.A.1
Harris, S.R.2
-
47
-
-
0020644952
-
Superoxide radical: An endogenous toxicant
-
Fridovich I. Superoxide radical: an endogenous toxicant. Annu Rev Pharmacol Toxicol 1983; 23:239-257.
-
(1983)
Annu Rev Pharmacol Toxicol
, vol.23
, pp. 239-257
-
-
Fridovich, I.1
-
48
-
-
84857934520
-
Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer's disease by exendin-4
-
Chen S, Liu AR, An FM, Yao WB, Gao XD. Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer's disease by exendin-4. Age (Dordr) 2011.
-
(2011)
Age (Dordr)
-
-
Chen, S.1
Liu, A.R.2
An, F.M.3
Yao, W.B.4
Gao, X.D.5
-
49
-
-
79251628354
-
Insulin receptor signaling in rat hippocampus: A study in STZ (ICV) induced memory deficit model
-
Agrawal R, Tyagi E, Shukla R, Nath C. Insulin receptor signaling in rat hippocampus: a study in STZ (ICV) induced memory deficit model. Eur Neuropsychopharmacol 2011; 21:261-273.
-
(2011)
Eur Neuropsychopharmacol
, vol.21
, pp. 261-273
-
-
Agrawal, R.1
Tyagi, E.2
Shukla, R.3
Nath, C.4
|