-
2
-
-
39649092973
-
Nanotechnology and cancer
-
Heath JR, Davis ME. Nanotechnology and cancer. Annu Rev Med 2008; 59:251-265
-
(2008)
Annu Rev Med
, vol.59
, pp. 251-265
-
-
Heath, J.R.1
Davis, M.E.2
-
3
-
-
38949192547
-
Targeted cancer therapy: Conferring specificity to cytotoxic drugs
-
Chari RV. Targeted cancer therapy: conferring specificity to cytotoxic drugs. Acc Chem Res 2008; 41:98-101.
-
(2008)
Acc Chem Res
, vol.41
, pp. 98-101
-
-
Chari, R.V.1
-
4
-
-
64549164046
-
Chemosensitization and immunosensitization of resistant cancer cells to apoptosis and inhibition of metastasis by the specific NFkappaB inhibitor DHMEQ
-
Katsman A, Umezawa K, Bonavida B. Chemosensitization and immunosensitization of resistant cancer cells to apoptosis and inhibition of metastasis by the specific NFkappaB inhibitor DHMEQ. Curr Pharm Des 2009; 15:792-808.
-
(2009)
Curr Pharm des
, vol.15
, pp. 792-808
-
-
Katsman, A.1
Umezawa, K.2
Bonavida, B.3
-
5
-
-
36849067019
-
Nanocarriers as an emerging platform for cancer therapy
-
DOI 10.1038/nnano.2007.387, PII NNANO2007387
-
Peer D, Karp JM, Hong S, Farokhzad OC, Margalit R, Langer R. Nanocarriers as an Emerging Platform for Cancer Therapy. Nature Nanotech 2007; 2:751-760 (Pubitemid 350223348)
-
(2007)
Nature Nanotechnology
, vol.2
, Issue.12
, pp. 751-760
-
-
Peer, D.1
Karp, J.M.2
Hong, S.3
Farokhzad, O.C.4
Margalit, R.5
Langer, R.6
-
6
-
-
14644439267
-
Cancer Nanotechnology: Opportunities and challenges
-
Ferrari M. Cancer Nanotechnology: opportunities and challenges. Nat Rev Cancer 2005; 5:161-171
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 161-171
-
-
Ferrari, M.1
-
7
-
-
70350767308
-
Formulation/ preparation of functionalized nanoparticles for in vivo targeted drug delivery
-
Gu F, Langer R, Farokhzad OC. Formulation/ preparation of functionalized nanoparticles for in vivo targeted drug delivery. Methods Mol Biol 2009; 544:589-598
-
(2009)
Methods Mol Biol
, vol.544
, pp. 589-598
-
-
Gu, F.1
Langer, R.2
Farokhzad, O.C.3
-
8
-
-
57649124218
-
The co-delivery of paclitaxel and Herceptin using cationic micellar nanoparticles
-
Lee AL, Wang Y, Cheng HY, Pervaiz S, Yang YY. The co-delivery of paclitaxel and Herceptin using cationic micellar nanoparticles. Biomaterials 2009; 30:919-927
-
(2009)
Biomaterials
, vol.30
, pp. 919-927
-
-
Lee, A.L.1
Wang, Y.2
Cheng, H.Y.3
Pervaiz, S.4
Yang, Y.Y.5
-
9
-
-
53049104252
-
Drug delivery with carbon nanotube for in vivo cancer treatment
-
Liu Z, Chen K, Davis C, Sherlock S, Cao Q, Chen X, et al. Drug delivery with carbon nanotube for in vivo cancer treatment. Cancer Res 2008; 68:6652-6660
-
(2008)
Cancer Res
, vol.68
, pp. 6652-6660
-
-
Liu, Z.1
Chen, K.2
Davis, C.3
Sherlock, S.4
Cao, Q.5
Chen, X.6
-
10
-
-
0037115543
-
Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs
-
Sapra P, Allen TM. Internalizing antibodies are necessary for improved therapeutic efficacy of antibody- targeted liposomal drugs. Cancer Res 2002; 62:7190-7194 (Pubitemid 36025236)
-
(2002)
Cancer Research
, vol.62
, Issue.24
, pp. 7190-7194
-
-
Sapra, P.1
Allenz, T.M.2
-
11
-
-
68149092641
-
MS-qFRET: A quantum dot-based method for analysis of DNA methylation
-
Epub ahead of print
-
Bailey VJ, Easwaran H, Zhang Y, Griffiths E, Belinsky SA, Herman JG, et al. MS-qFRET: A quantum dot-based method for analysis of DNA methylation. Genome Res 2009; Epub ahead of print.
-
(2009)
Genome Res
-
-
Bailey, V.J.1
Easwaran, H.2
Zhang, Y.3
Griffiths, E.4
Belinsky, S.A.5
Herman, J.G.6
-
12
-
-
70449705990
-
Hydrotropic oligomer-conjugated glycol chitosan as a carrier of paxclitaxel: Synthesis, characterization and in vivo biodistribution
-
Epub ahead of print
-
Saravanakumar G, Min KH, Min DS, Kim AY, Lee CM, Cho YW, et al. Hydrotropic oligomer-conjugated glycol chitosan as a carrier of paxclitaxel: Synthesis, characterization and in vivo biodistribution. J Controlled Release 2009; Epub ahead of print.
-
(2009)
J Controlled Release
-
-
Saravanakumar, G.1
Min, K.H.2
Min, D.S.3
Kim, A.Y.4
Lee, C.M.5
Cho, Y.W.6
-
13
-
-
70350780521
-
Nanoparticle-mediated gene delivery
-
Jin S, Leach JC, Ye K. Nanoparticle-mediated gene delivery. Methods Mol. Biol 2009; 544:547-557
-
(2009)
Methods Mol. Biol
, vol.544
, pp. 547-557
-
-
Jin, S.1
Leach, J.C.2
Ye, K.3
-
14
-
-
67849118615
-
Pharmacokinetics and bone formation by BMP-2 entrapped in polyethylenimine- Coated albumin nanoparticle
-
Epub ahead of print
-
Zhang S, Doschak MR, Uludaq H. Pharmacokinetics and bone formation by BMP-2 entrapped in polyethylenimine- coated albumin nanoparticle. Biomaterials 2009; Epub ahead of print.
-
(2009)
Biomaterials
-
-
Zhang, S.1
Doschak, M.R.2
Uludaq, H.3
-
15
-
-
62649139973
-
ICAM-1 targeting of doxorubicin- Loaded PLGA nanoparticles to lung epithelial cells
-
Chittasupho C, Xie SX, Baoum A, Yakovleva T, Siahaan TJ, Berkland CJ. ICAM-1 targeting of doxorubicin- loaded PLGA nanoparticles to lung epithelial cells. Eur J Pharm 2009; 37:141-150
-
(2009)
Eur J Pharm
, vol.37
, pp. 141-150
-
-
Chittasupho, C.1
Xie, S.X.2
Baoum, A.3
Yakovleva, T.4
Siahaan, T.J.5
Berkland, C.J.6
-
16
-
-
0034644539
-
Cell signaling by receptor tyrosine kinase
-
Schlessinger J. Cell signaling by receptor tyrosine kinase. Cell 2000; 103:211-225
-
(2000)
Cell
, vol.103
, pp. 211-225
-
-
Schlessinger, J.1
-
17
-
-
2342591455
-
The discovery of receptor tyrosine kinases: Targets for cancer therapy
-
Gschwind A, Fischer OM, Ullrich A. The discovery of receptor tyrosine kinase: targets for cancer therapy. Nature Rev Cancer 2004; 4:361-370 (Pubitemid 38579482)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.5
, pp. 361-370
-
-
Gschwind, A.1
Fischer, O.M.2
Ullrich, A.3
-
18
-
-
33745325007
-
Mechanism of drug inhibition of signaling molecules
-
Sebolt-Leopold JS, English JM. Mechanism of drug inhibition of signaling molecules. Nature 2006; 441:457-462
-
(2006)
Nature
, vol.441
, pp. 457-462
-
-
Sebolt-Leopold, J.S.1
English, J.M.2
-
19
-
-
0024478054
-
p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor
-
Hudziak RM, Lewis GD, Winget M, Fendly BM, Shepard HM, Ullrich A. p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor. Mol Cell Biol 1989; 9:1165-1172
-
(1989)
Mol Cell Biol
, vol.9
, pp. 1165-1172
-
-
Hudziak, R.M.1
Lewis, G.D.2
Winget, M.3
Fendly, B.M.4
Shepard, H.M.5
Ullrich, A.6
-
20
-
-
0025318271
-
Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product
-
Fendly BM, Winget M, Hudziak RM, Lipari MT, Napier MT, Ullrich A. Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product. Cancer Res 1990; 50:1550-1558 (Pubitemid 20090470)
-
(1990)
Cancer Research
, vol.50
, Issue.5
, pp. 1550-1558
-
-
Fendly, B.M.1
Winget, M.2
Hudziak, R.M.3
Lipari, M.T.4
Napier, M.A.5
Ullrich, A.6
-
21
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
DOI 10.1056/NEJMoa022457
-
O'Brien SG, Guilhot F, Larson RA, Gathmann I, Baccarani M, Cervantes F, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. New Engl J Med 2003; 348:994-1004. (Pubitemid 36302244)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.11
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
Gathmann, I.4
Baccarani, M.5
Cervantes, F.6
Cornelissen, J.J.7
Fischer, T.8
Hochhaus, A.9
Hughes, T.10
Lechner, K.11
Nielsen, J.L.12
Rousselot, P.13
Reiffers, J.14
Saglio, G.15
Shepherd, J.16
Simonsson, B.17
Gratwohl, A.18
Goldman, J.M.19
Kantarjian, H.20
Taylor, K.21
Verhoef, G.22
Bolton, A.E.23
Capdeville, R.24
Druker, B.J.25
more..
-
22
-
-
0036782278
-
VEGF and the quest for tumour angiogenesis factors
-
DOI 10.1038/nrc909
-
Ferrara N. VEGF and the quest for tumor angiogenesis factors. Nature Rev Cancer 2002; 2:795-803. (Pubitemid 37328914)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.10
, pp. 795-803
-
-
Ferrara, N.1
-
23
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. New Engl J Med 1971; 285:1182-1186
-
(1971)
New Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
24
-
-
0030856731
-
Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders
-
Presta LG, Chen H, O'Connor SJ, Chisholm V, Meng YG, Krummen L, et al. Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders. Cancer Res 1997; 57:4593-4599 (Pubitemid 27441066)
-
(1997)
Cancer Research
, vol.57
, Issue.20
, pp. 4593-4599
-
-
Presta, L.G.1
Chen, H.2
O'Connor, S.J.3
Chisholm, V.4
Meng, Y.G.5
Krummen, L.6
Winkler, M.7
Ferrara, N.8
-
25
-
-
0032893263
-
SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types
-
Fong TA, Shawver LK, Sun L, Tang C, App H, Powell TJ, et al. SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization and growth of multiple tumor types. Cancer Res 1999; 59:99-106. (Pubitemid 29062964)
-
(1999)
Cancer Research
, vol.59
, Issue.1
, pp. 99-106
-
-
Fong, T.A.T.1
Shawver, L.K.2
Sun, L.3
Tang, C.4
App, H.5
Powell, T.J.6
Kim, Y.H.7
Schreck, R.8
Wang, X.9
Risau, W.10
Ullrich, A.11
Hirth, K.P.12
McMahon, G.13
-
26
-
-
0033231069
-
Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis
-
Shaheen RM, Davis DW, Liu W, Zebrowski BK, Wilson MR, Bucana CD, et al. Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. Cancer Res 1999; 59:5412-5416 (Pubitemid 29526446)
-
(1999)
Cancer Research
, vol.59
, Issue.21
, pp. 5412-5416
-
-
Shaheen, R.M.1
Davis, D.W.2
Liu, W.3
Zebrowski, B.K.4
Wilson, M.R.5
Bucana, C.D.6
McConkey, D.J.7
McMahon, G.8
Ellis, L.M.9
-
27
-
-
0033380090
-
Signaling networks that cause cancer
-
McCormick F. Signaling networks that cause cancer. Trends Cell Biol 1999; 9:53-56
-
(1999)
Trends Cell Biol
, vol.9
, pp. 53-56
-
-
McCormick, F.1
-
28
-
-
0142227019
-
Targeting the PI3K-Akt pathway in human cancer: Rationale and promise
-
DOI 10.1016/S1535-6108(03)00248-4
-
Luo J, Manning BD, Cantley LC. Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 2003; 4:257-262 (Pubitemid 37329790)
-
(2003)
Cancer Cell
, vol.4
, Issue.4
, pp. 257-262
-
-
Luo, J.1
Manning, B.D.2
Cantley, L.C.3
-
29
-
-
33745307617
-
Ras, PI(3)K and mTOR signalling controls tumour cell growth
-
DOI 10.1038/nature04869, PII NATURE04869
-
Shaw RJ, Cantley LC. Ras, PI(3)K and mTOR signaling controls tumor cell growth. Nature 2006; 441:424-430 (Pubitemid 44050136)
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 424-430
-
-
Shaw, R.J.1
Cantley, L.C.2
-
30
-
-
0037264633
-
Targeting RAS signaling pathways in cancer chemotherapy
-
Downword J. Targeting RAS signaling pathways in cancer chemotherapy. Nat Rev Cancer 2002; 3:11-22.
-
(2002)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downword, J.1
-
31
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Begnelli GR, Cox C, Stephens P, Edkins S, Clegg S, et al. Mutations of the BRAF gene in human cancer. Nature 2002; 417:949-954
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Begnelli, G.R.2
Cox, C.3
Stephens, P.4
Edkins, S.5
Clegg, S.6
-
32
-
-
38949183695
-
Advances in targeting the Ras/ Raf/MEK/Erk mitogen activated protein kinase cascade with MEK inhibitors for cancer therapy
-
Friday BB, Adjei AA. Advances in targeting the Ras/ Raf/MEK/Erk mitogen activated protein kinase cascade with MEK inhibitors for cancer therapy. Clin Cancer Res 2008; 14:342-346
-
(2008)
Clin Cancer Res
, vol.14
, pp. 342-346
-
-
Friday, B.B.1
Adjei, A.A.2
-
33
-
-
0023256456
-
Prevalence of ras gene mutation in human colorectal cancers
-
Bos JL, Fearon ER, Hamilton SR, Vries MV, van Boom JH, van der Eb AJ, et al. Prevalence of ras gene mutation in human colorectal cancers. Nature 1987; 327:293-297
-
(1987)
Nature
, vol.327
, pp. 293-297
-
-
Bos, J.L.1
Fearon, E.R.2
Hamilton, S.R.3
Vries, M.V.4
Van Boom, J.H.5
Van Der Eb, A.J.6
-
34
-
-
5444227865
-
Guilty as charged: B-RAF is a human oncogene
-
DOI 10.1016/j.ccr.2004.09.022, PII S153561080400279X
-
Garnett MJ, Marais R. Guilty as charged: B-RAF is a human oncogene. Cancer Cell 2004; 6:313-319 (Pubitemid 39361432)
-
(2004)
Cancer Cell
, vol.6
, Issue.4
, pp. 313-319
-
-
Garnett, M.J.1
Marais, R.2
-
37
-
-
0033590636
-
Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors
-
DOI 10.1038/sj.onc.1202367
-
Hoshino R, Chatani Y, Yamori T, Tsuruo T, Oka H, Yoshida O, et al. Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors. Oncogene 1999; 18:813-822 (Pubitemid 29080340)
-
(1999)
Oncogene
, vol.18
, Issue.3
, pp. 813-822
-
-
Hoshino, R.1
Chatani, Y.2
Yamori, T.3
Tsuruo, T.4
Oka, H.5
Yoshida, O.6
Shimada, Y.7
Ari-I, S.8
Wada, H.9
Fujimoto, J.10
Kohno, M.11
-
38
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, Feeser WS, et al. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 1998; 273:18623-18632
-
(1998)
J Biol Chem
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
Feeser, W.S.6
-
39
-
-
10344231333
-
Preclinical development of ARRY- 142886, a potent and selective MEK inhibitor
-
Wallace E, et al. Preclinical development of ARRY- 142886, a potent and selective MEK inhibitor. Proc Annu Meet Am Assoc Cancer Res 2004; 45:3891.
-
(2004)
Proc Annu Meet Am Assoc Cancer Res
, vol.45
, pp. 3891
-
-
Wallace, E.1
-
40
-
-
0038649977
-
Targeting of mitogen-activated protein kinases and phosphatidylinositol 3 kinase inhibits hepatocyte growth factor/scatter factor - Induced angiogenesis
-
DOI 10.1161/01.CIR.0000077501.19266.E5
-
Sengupta S, Sellers LA, Li RC, Gherardi E, Zhao G, Watson N, et al. Targeting of mitogen-activated protein kinases and phosphatidylinositol 3 kinase inhibits hepatocyte growth factor/scatter factor-induced angiogenesis. Circulation 2003; 107:2955-2961 (Pubitemid 36736639)
-
(2003)
Circulation
, vol.107
, Issue.23
, pp. 2955-2961
-
-
Sengupta, S.1
Sellers, L.A.2
Li, R.-C.3
Gherardi, E.4
Zhao, G.5
Watson, N.6
Sasisekharan, R.7
Fan, T.-P.D.8
-
41
-
-
32044466838
-
Exploiting the PI3K/AKT pathway for cancer drug discovery
-
Hennessy BT, Smith DL, Ram PT, Lu Y, Mills GB. Exploiting the PI3K/AKT pathway for cancer drug discovery. Nature Rev Drug Discov 2005; 4:988-1004.
-
(2005)
Nature Rev Drug Discov
, vol.4
, pp. 988-1004
-
-
Hennessy, B.T.1
Smith, D.L.2
Ram, P.T.3
Lu, Y.4
Mills, G.B.5
-
42
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell 2006; 124:471-484
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
43
-
-
34347220473
-
Defining the role of mTOR in cancer
-
Guertin DA, Sabatini DM. Defining the role of mTOR in cancer. Cancer Cell 2007; 12:9-22.
-
(2007)
Cancer Cell
, vol.12
, pp. 9-22
-
-
Guertin, D.A.1
Sabatini, D.M.2
-
44
-
-
43049131769
-
Targeting the PI3K/Akt/mTOR pathway: Effective combinations and clinical considerations
-
LiPiccolo J, Blumenthal GM, Bernstein WD, Dennis PA. Targeting the PI3K/Akt/mTOR pathway: effective combinations and clinical considerations. Drug Resist Updat 2008; 11:32-50.
-
(2008)
Drug Resist Updat
, vol.11
, pp. 32-50
-
-
LiPiccolo, J.1
Blumenthal, G.M.2
Bernstein, W.D.3
Dennis, P.A.4
-
45
-
-
26644449670
-
The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells
-
DOI 10.1016/j.ccr.2005.09.006, PII S1535610805002990
-
She QB, Solit DB, Ye Q, O'Reilly KE, Lobo J, Rosen N. The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells. Cancer Cell 2005; 8:287-297 (Pubitemid 41443414)
-
(2005)
Cancer Cell
, vol.8
, Issue.4
, pp. 287-297
-
-
She, Q.-B.1
Solit, D.B.2
Ye, Q.3
O'Reilly, K.E.4
Lobo, J.5
Rosen, N.6
-
46
-
-
70449712809
-
Nanopharmaceuticals: Challenges and Regulatory Perspective
-
De Villiers MM, Aramwit P, Kwon GS, eds. Springer NY
-
Shah RA, Khan MA. Nanopharmaceuticals: Challenges and Regulatory Perspective. De Villiers MM, Aramwit P, Kwon GS, eds. Nanotechnology in Drug Delivery. Springer NY 2009; 621-646
-
(2009)
Nanotechnology in Drug Delivery
, pp. 621-646
-
-
Shah, R.A.1
Khan, M.A.2
-
47
-
-
0037449499
-
A computational model for particle size influence on drug absorption during controlled-release colonic delivery
-
Waterman KC, Sutton SC. A computational model for particle size influence on drug absorption during controlled-release colonic delivery. J Controlled Release 2003; 86:293-304.
-
(2003)
J Controlled Release
, vol.86
, pp. 293-304
-
-
Waterman, K.C.1
Sutton, S.C.2
-
48
-
-
34548385316
-
Nanoparticle albumin-bound paclitaxel: A novel Cremphor-EL-free formulation of paclitaxel
-
DOI 10.2217/17435889.2.4.415
-
Stinchcombe TE. Nanoparticle albumin-bound paclitaxel: a novel Cremophor-EL-free formulation of paclitaxel. Nanomedicine 2007; 2:415-423 (Pubitemid 47365124)
-
(2007)
Nanomedicine
, vol.2
, Issue.4
, pp. 415-423
-
-
Stinchcombe, T.E.1
-
49
-
-
79955007701
-
Cyclosporin-A incorporated cationic solid lipid nanoparticles for ocular delivery
-
epub ahead of print
-
Basaran E, Demirel M, Sirmagul B, Yazan Y. Cyclosporin-A incorporated cationic solid lipid nanoparticles for ocular delivery. J Microencapsul 2009; epub ahead of print.
-
(2009)
J Microencapsul
-
-
Basaran, E.1
Demirel, M.2
Sirmagul, B.3
Yazan, Y.4
-
50
-
-
34548604275
-
Optimizing efficacy of amphotericin B through nanomodification
-
Vyas SP, Gupta S. Optimizing efficacy of amphotericin B through nanomodification. Int J Nanomedicine 2006; 1:417-432
-
(2006)
Int J Nanomedicine
, vol.1
, pp. 417-432
-
-
Vyas, S.P.1
Gupta, S.2
-
51
-
-
65149083117
-
Pharmacokinetics and biodistribution of near-infrared fluorescent polymeric nanoparticles
-
Yang Z, Leon J, Martin M, Harder JW, Zhang R, Liang D, et al. Pharmacokinetics and biodistribution of near-infrared fluorescent polymeric nanoparticles. Nanotechnology 2009; 20:1-10.
-
(2009)
Nanotechnology
, vol.20
, pp. 1-10
-
-
Yang, Z.1
Leon, J.2
Martin, M.3
Harder, J.W.4
Zhang, R.5
Liang, D.6
-
52
-
-
34548482374
-
Stealth liposomes: Review of the basic science, rationale and clinical applications, existing and potential
-
Immordino ML, Dosio F, Cattel L. Stealth liposomes: review of the basic science, rationale and clinical applications, existing and potential. Int J Nanomed 2006; 1:297-315.
-
(2006)
Int J Nanomed
, vol.1
, pp. 297-315
-
-
Immordino, M.L.1
Dosio, F.2
Cattel, L.3
-
53
-
-
57749108568
-
In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities
-
Bisht S, Feldman G, Koorstra J-BM, Mullendore M, Alvarez H, Karikari C, et al. In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities. Mol Cancer Ther 2008; 7:3878-3888
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 3878-3888
-
-
Bisht, S.1
Feldman, G.2
Koorstra, J.-B.M.3
Mullendore, M.4
Alvarez, H.5
Karikari, C.6
-
54
-
-
60049090585
-
Design of biodegradable nanoparticles for oral delivery of doxorubicin: In vivo pharmacokinetics and toxicity studies in rats
-
Kalaria DR, Sharma G, Beniwal V, Ravi Kumar MNV. Design of biodegradable nanoparticles for oral delivery of doxorubicin: in vivo pharmacokinetics and toxicity studies in rats. Pharm Res 2009; 26:492-501.
-
(2009)
Pharm Res
, vol.26
, pp. 492-501
-
-
Kalaria, D.R.1
Sharma, G.2
Beniwal, V.3
Ravi Kumar, M.N.V.4
-
55
-
-
29244472857
-
Neuroscience nanotechnology: Progress, opportunities and challenges
-
DOI 10.1038/nrn1827
-
Silva GA. Neuroscience nanotechnology: progress, opportunities and challenges. Nat Rev Neuroscience 2006; 7:65-74. (Pubitemid 41828932)
-
(2006)
Nature Reviews Neuroscience
, vol.7
, Issue.1
, pp. 65-74
-
-
Silva, G.A.1
-
56
-
-
0032712180
-
Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles
-
Gulyaev AE, Gelperina SE, Skidan IN, Antropov AS, Kivman GY, Kreuter J. Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles. Pharm Res 1999; 6:564-569
-
(1999)
Pharm Res
, vol.6
, pp. 564-569
-
-
Gulyaev, A.E.1
Gelperina, S.E.2
Skidan, I.N.3
Antropov, A.S.4
Kivman, G.Y.5
Kreuter, J.6
-
57
-
-
12144288634
-
Chemotherapy of gioblastoma in rats using doxorubicin-loaded nanoparticles
-
Steiniger SC, Kreuter J, Khalansky AS, Skidan IN, Bobruskin AI, Smir nova ZS, et al. Chemotherapy of gioblastoma in rats using doxorubicin-loaded nanoparticles. Int J Cancer 2004; 109:759-767
-
(2004)
Int J Cancer
, vol.109
, pp. 759-767
-
-
Steiniger, S.C.1
Kreuter, J.2
Khalansky, A.S.3
Skidan, I.N.4
Bobruskin, A.I.5
Smirnova, Z.S.6
-
58
-
-
65249105506
-
Nanotechnology approach for drug addiction therapy: Gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neurons
-
Bonoiua AC, Mahajan SD, Ding H, Roy I, Yong K-T, Kumar R, et al. Nanotechnology approach for drug addiction therapy: gene silencing using delivery of gold nanorod-siRNA nanoplex in dopaminergic neurons. Proc Natl Acad Sci 2009; 106:5546-5550
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 5546-5550
-
-
Bonoiua, A.C.1
Mahajan, S.D.2
Ding, H.3
Roy, I.4
Yong, K.-T.5
Kumar, R.6
-
59
-
-
67349131897
-
Combination chemotherapeutic dry powder aerosols via controlled nanoparticle agglomeration
-
El-Gendy N, Berkland C. Combination chemotherapeutic dry powder aerosols via controlled nanoparticle agglomeration. Pharm Res 2009; 26:1752-1763
-
(2009)
Pharm Res
, vol.26
, pp. 1752-1763
-
-
El-Gendy, N.1
Berkland, C.2
-
62
-
-
41949107530
-
Intravenous tolerance of a nanoparticle-based formulation of doxorubicin in healthy rats
-
Pereverzava E, Treschalin I, Bodyagin D, Maksimenko O, Kreuter J, Gelperina S. Intravenous tolerance of a nanoparticle-based formulation of doxorubicin in healthy rats. Toxicol Lett 2008; 178:9-19.
-
(2008)
Toxicol Lett
, vol.178
, pp. 9-19
-
-
Pereverzava, E.1
Treschalin, I.2
Bodyagin, D.3
Maksimenko, O.4
Kreuter, J.5
Gelperina, S.6
-
64
-
-
50249159611
-
Targeted single-wall carbon Nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device
-
Dhar S, Liu Z, Thomale J, Dai H, Lippard SJ. Targeted single-wall carbon Nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device. J Am Chem Soc 2008; 130:11467-11476
-
(2008)
J Am Chem Soc
, vol.130
, pp. 11467-11476
-
-
Dhar, S.1
Liu, Z.2
Thomale, J.3
Dai, H.4
Lippard, S.J.5
-
65
-
-
67249148163
-
Targeted systemic delivery of a therapeutic siRNA with a multifunctional carrier controls tumor proliferation in mice
-
Wang XL, Xu R, Wu X, Gillespie D, Jensen R, Lu ZR. Targeted systemic delivery of a therapeutic siRNA with a multifunctional carrier controls tumor proliferation in mice. Mol Pharm 2009; 6:738-746
-
(2009)
Mol Pharm
, vol.6
, pp. 738-746
-
-
Wang, X.L.1
Xu, R.2
Wu, X.3
Gillespie, D.4
Jensen, R.5
Lu, Z.R.6
-
66
-
-
64149113037
-
Internally cationic polyamidoamine PAMAM-OH dendrimers for siRNA delivery: Effect of the degree of quaternization and cancer targeting
-
Patil ML, Zhang M, Taratula O, Garbuzenko OB, He H, Minko T. Internally cationic polyamidoamine PAMAM-OH dendrimers for siRNA delivery: effect of the degree of quaternization and cancer targeting. Biomacromolecules 2009; 10:258-266
-
(2009)
Biomacromolecules
, vol.10
, pp. 258-266
-
-
Patil, M.L.1
Zhang, M.2
Taratula, O.3
Garbuzenko, O.B.4
He, H.5
Minko, T.6
-
67
-
-
70349785875
-
Paclitaxel-loaded PLGA nanoparticles surface modified with transferrin and Pluronic((R))P85, an in vitro cell line and in vivo biodistribution studies on rat model
-
Shah N, Chaudhari K, Dantuluri P, Murthy RS, Das S. Paclitaxel-loaded PLGA nanoparticles surface modified with transferrin and Pluronic((R))P85, an in vitro cell line and in vivo biodistribution studies on rat model. J Drug Target 2009; 17:533-542
-
(2009)
J Drug Target
, vol.17
, pp. 533-542
-
-
Shah, N.1
Chaudhari, K.2
Dantuluri, P.3
Murthy, R.S.4
Das, S.5
-
68
-
-
67649876262
-
Fluorescent tumor imaging of type I IGF receptor in vivo: Comparison of antibody-conjugated quantum dots and small-molecule fluorophore
-
Zhang H, Zeng X, Li Q, Gaillard-Kelly M, Wagner CR, Yee D. Fluorescent tumor imaging of type I IGF receptor in vivo: comparison of antibody-conjugated quantum dots and small-molecule fluorophore. Br J Cancer 2009; 101:71-79
-
(2009)
Br J Cancer
, vol.101
, pp. 71-79
-
-
Zhang, H.1
Zeng, X.2
Li, Q.3
Gaillard-Kelly, M.4
Wagner, C.R.5
Yee, D.6
-
69
-
-
34648825528
-
Biomimetic glycoliposomes as nanocarriers for targeting P-selectin on activated platelets
-
DOI 10.1021/bc700212b
-
Zhu J, Xue J, Guo Z, Zhang L, Marchant RE. Biomimetic glycoliposomes as nanocarriers for targeting P-selectin on activated platelets. Bioconj Chem 2007; 18:1366-1369 (Pubitemid 47464040)
-
(2007)
Bioconjugate Chemistry
, vol.18
, Issue.5
, pp. 1366-1369
-
-
Zhu, J.1
Xue, J.2
Guo, Z.3
Zhang, L.4
Marchant, R.E.5
-
71
-
-
0037345799
-
Bioinspired pH-responsive polymers for the intracellular delivery of biomolecular drugs
-
DOI 10.1021/bc020056d
-
Murthy N, Campbell J, Fausto N, Hoffman AS, Stayton PS. Bioinspired pH-responsive polymers for the intracellular delivery of biomolecular drugs. Bioconj Chem 2003; 14:412-419 (Pubitemid 36348665)
-
(2003)
Bioconjugate Chemistry
, vol.14
, Issue.2
, pp. 412-419
-
-
Murthy, N.1
Campbell, J.2
Fausto, N.3
Hoffman, A.S.4
Stayton, P.S.5
-
73
-
-
34548028250
-
Gold nanoparticles enable selective light-induced contents release from liposomes
-
DOI 10.1016/j.jconrel.2007.06.009, PII S0168365907002970
-
Paasonen L, Laaksonen T, Johans C, Yliperttula M, Kontturi K, Urtti A. Gold nanoparticles enable selective light-induced contents release from liposomes. J Controlled Release 2007; 122:86-91. (Pubitemid 47284557)
-
(2007)
Journal of Controlled Release
, vol.122
, Issue.1
, pp. 86-93
-
-
Paasonen, L.1
Laaksonen, T.2
Johans, C.3
Yliperttula, M.4
Kontturi, K.5
Urtti, A.6
-
74
-
-
66349119914
-
Electrical-sensitive nanoparticle composed of chitosan and tetraethyl orthosilicate for controlled drug release
-
Liu KH, Liu TY, Liu DM, Chen SY. Electrical-sensitive nanoparticle composed of chitosan and tetraethyl orthosilicate for controlled drug release. J Nanosci Nanotechnol 2009; 9:1198-1203
-
(2009)
J Nanosci Nanotechnol
, vol.9
, pp. 1198-1203
-
-
Liu, K.H.1
Liu, T.Y.2
Liu, D.M.3
Chen, S.Y.4
-
75
-
-
60049101453
-
Magnetothermally-responsive nanomaterials: Combining magnetic nanostructures and thermally- Sensitive polymers for triggered drug release
-
Brazel CS. Magnetothermally-responsive nanomaterials: combining magnetic nanostructures and thermally- sensitive polymers for triggered drug release. Pharm Res 2009; 26:644-656
-
(2009)
Pharm Res
, vol.26
, pp. 644-656
-
-
Brazel, C.S.1
-
76
-
-
0035981078
-
Environment-sensitive hydrogels for drug delivery
-
Qiu Y, Park K. Environment-sensitive hydrogels for drug delivery. Advanced Drug Deliv Rev 2001; 53:321-339
-
(2001)
Advanced Drug Deliv Rev
, vol.53
, pp. 321-339
-
-
Qiu, Y.1
Park, K.2
-
77
-
-
44149127417
-
Liposomes in ultrasonic drug and gene delivery
-
Huang S-L. Liposomes in ultrasonic drug and gene delivery. Advanced Drug Deliv Rev 2008; 60:1167-1176
-
(2008)
Advanced Drug Deliv Rev
, vol.60
, pp. 1167-1176
-
-
Huang, S.-L.1
-
78
-
-
33845296078
-
Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug
-
DOI 10.1016/j.jconrel.2006.07.012, PII S016836590600335X
-
Ahmed F, Pakunlu RI, Brannan A, Bates F, Minko T, Discher DE. Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate an shrink tumors, inducing apoptosis in proportion to accumulated drug. J Controlled Release 2006; 116:150-158 (Pubitemid 44868999)
-
(2006)
Journal of Controlled Release
, vol.116
, Issue.2 SPEC. ISS
, pp. 150-158
-
-
Ahmed, F.1
Pakunlu, R.I.2
Brannan, A.3
Bates, F.4
Minko, T.5
Discher, D.E.6
-
79
-
-
23144456813
-
Novel cancer therapy through temporal targeting of both tumor cells and neovasculature using a unique nanoscale delivery system
-
Sengupta S, Eavarone DA, Capila I, Zhao G, Watson N, Kiziltepe T, et al. Novel cancer therapy through temporal targeting of both tumor cells and neovasculature using a unique nanoscale delivery system. Nature 2005; 436:568-572
-
(2005)
Nature
, vol.436
, pp. 568-572
-
-
Sengupta, S.1
Eavarone, D.A.2
Capila, I.3
Zhao, G.4
Watson, N.5
Kiziltepe, T.6
-
80
-
-
35549013192
-
Apoptotic epidermal growth factor (EGF)-conjugated block copolymer micelles as a nanotechnology platform for targeted combination therapy
-
Lee H, Hu M, Reilly RM, Allen C. Apoptotic epidermal growth factor (EGF)-conjugated block copolymer micelles as a nanotechnology platform for targeted combination therapy. Mol Pharm 2007; 4:769-781
-
(2007)
Mol Pharm
, vol.4
, pp. 769-781
-
-
Lee, H.1
Hu, M.2
Reilly, R.M.3
Allen, C.4
-
81
-
-
57749188299
-
Targeting cancer with small molecule kinase inhibitors
-
Zhang J, Yang PL, Gray NS. Targeting cancer with small molecule kinase inhibitors. Nature Rev Cancer 2009; 9:28-39.
-
(2009)
Nature Rev Cancer
, vol.9
, pp. 28-39
-
-
Zhang, J.1
Yang, P.L.2
Gray, N.S.3
-
82
-
-
33751106653
-
New approaches to molecular cancer therapeutics
-
DOI 10.1038/nchembio840, PII NCHEMBIO840
-
Collins I, Workman P. New approaches to molecular cancer therapeutics. Nature Chem Biol 2006; 2:689-700. (Pubitemid 44764211)
-
(2006)
Nature Chemical Biology
, vol.2
, Issue.12
, pp. 689-700
-
-
Collins, I.1
Workman, P.2
-
83
-
-
66049083487
-
Nanoparticle-mediated targeting of MAPK signaling predisposes tumor to chemotherapy
-
Basu S, Harfouche R, Soni S, Chimote G, Mashelkar RA, Sengupta S. Nanoparticle-mediated targeting of MAPK signaling predisposes tumor to chemotherapy. Proc Natl Acad Sci 2009; 106:7957-7961
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 7957-7961
-
-
Basu, S.1
Harfouche, R.2
Soni, S.3
Chimote, G.4
Mashelkar, R.A.5
Sengupta, S.6
-
84
-
-
71249093831
-
Nanoparticle-mediated targeting of phosphatidylinositol-3-kinase signaling inhibits angiogenesis
-
in press
-
Harfouche R, Basu S, Soni S, Hentschel DM, Mashelkar RA, Sengupta S. Nanoparticle-mediated targeting of phosphatidylinositol-3-kinase signaling inhibits angiogenesis. Angiogenesis 2009; (in press).
-
(2009)
Angiogenesis
-
-
Harfouche, R.1
Basu, S.2
Soni, S.3
Hentschel, D.M.4
Mashelkar, R.A.5
Sengupta, S.6
-
86
-
-
40149088986
-
Prodrugs: Design and clinical applications
-
Rautio J, Kumpulainen H, Heimbach T, Oliyai R, Oh D, Jarvinen T, et al. Prodrugs: design and clinical applications. Nature Rev Drug Discov 2005; 7:255-270
-
(2005)
Nature Rev Drug Discov
, vol.7
, pp. 255-270
-
-
Rautio, J.1
Kumpulainen, H.2
Heimbach, T.3
Oliyai, R.4
Oh, D.5
Jarvinen, T.6
-
87
-
-
23844438209
-
Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition
-
Sun SY, Rosenberg LM, Wang X, Zhou Z, Yue P, Fu H, et al. Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition. Cancer Res 2005; 65:7052-7058
-
(2005)
Cancer Res
, vol.65
, pp. 7052-7058
-
-
Sun, S.Y.1
Rosenberg, L.M.2
Wang, X.3
Zhou, Z.4
Yue, P.5
Fu, H.6
-
88
-
-
17144370268
-
LY294002 and rapamycin co-operate to inhibit T-cell proliferation
-
DOI 10.1038/sj.bjp.0706061
-
Breslin EM, White PC, Shore AM, Clement M, Brennan P. LY294002 and rapamycin co-operate to inhibit T-cell proliferation. Br J Pharmacol 2005; 144:791-800. (Pubitemid 40516119)
-
(2005)
British Journal of Pharmacology
, vol.144
, Issue.6
, pp. 791-800
-
-
Breslin, E.M.1
White, P.C.2
Shore, A.M.3
Clement, M.4
Brennan, P.5
-
89
-
-
23844505960
-
2-terminal kinase pathways: An effective therapeutic strategy for lung cancer
-
DOI 10.1158/1078-0432.CCR-05-0009
-
Lee HY, Oh SH, Suh YA, Baek JH, Papadimitrakopoulou V, Huang S, et al. Response of non-small cell lung cancer cells to the inhibitors of phosphatidylinositol 3-kinase/Akt- and MAPK kinase 4/c-Jun NH2-terminal kinase pathways: an effective therapeutic strategy for lung cancer. Clin. Cancer Res 2005; 11:6065-6074 (Pubitemid 41170339)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.16
, pp. 6065-6074
-
-
Lee, H.-Y.1
Oh, S.-H.2
Suh, Y.-A.3
Baek, J.H.4
Papadimitrakopoulou, V.5
Huang, S.6
Hong, W.K.7
-
90
-
-
55549129243
-
ABT-869, a multi-targeted tyrosine kinase inhibitor, in combination with rapamycin is effective for subcutaneous hepatocellular carcinoma xenograft
-
Jasinghe VJ, Xie Z, Zhou J, Khng J, Poon LF, Senthilnathan P, et al. ABT-869, a multi-targeted tyrosine kinase inhibitor, in combination with rapamycin is effective for subcutaneous hepatocellular carcinoma xenograft. J Hepatol 2008; 49:985-997
-
(2008)
J Hepatol
, vol.49
, pp. 985-997
-
-
Jasinghe, V.J.1
Xie, Z.2
Zhou, J.3
Khng, J.4
Poon, L.F.5
Senthilnathan, P.6
-
91
-
-
58149153118
-
Modulating effect of the PI3- Kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cells
-
Fujiwara M, Izuishi K, Sano T, Hossain MA, Kimura S, Masaki T, et al. Modulating effect of the PI3- kinase inhibitor LY294002 on cisplatin in human pancreatic cancer cells. J Exp Clin Cancer Res 2008; 27:76-84.
-
(2008)
J Exp Clin Cancer Res
, vol.27
, pp. 76-84
-
-
Fujiwara, M.1
Izuishi, K.2
Sano, T.3
Hossain, M.A.4
Kimura, S.5
Masaki, T.6
|