Dexamethasone-loaded peptide micelles for delivery of the heme oxygenase-1 gene to ischemic brain

Journal of Controlled Release

Volumn 158, Issue 1, 2012, Pages 131-138

  Lee, Jiyoung ^a   Hyun, Hyesun ^a   Kim, Jinyoung ^a   Ryu, Jae Hwan ^a   Kim, Hyun Ah ^a   Park, Ji Hwan ^a   Lee, Minhyung ^a  

^a Hanyang University   (South Korea)

Author keywords

Gene delivery; Gene therapy; Micelle; Peptide; Stroke

Indexed keywords

293 CELLS; CYTOKINES; DEXAMETHASONES; FLUORESCENT DYES; GENE CARRIER; GENE DELIVERY; HEME OXYGENASE-1; HEME OXYGENASE-1 GENE; HUMAN EMBRYONIC KIDNEYS; HYDROPHOBIC CORE; INFARCT SIZE; INTERLEUKIN-6; ISCHEMIA REPERFUSION; LIPOPOLYSACCHARIDES; MICELLE STRUCTURE; MIDDLE CEREBRAL ARTERY; PLASMID DNA; POLY-L-LYSINE; SELF-ASSEMBLED; STROKE; TRANSFECTION EFFICIENCY;

AMINO ACIDS; GENE THERAPY; GENE TRANSFER; HYDROPHOBICITY; MICELLES; PORPHYRINS;

PEPTIDES;

DEXAMETHASONE; GENE THERAPY AGENT; HEME OXYGENASE 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PEPTIDE; PLASMID DNA; POLYLYSINE; R3V6 PEPTIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; GENE DELIVERY SYSTEM; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; MALE; MICELLE; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; BRAIN ISCHEMIA; CELL LINE; CELL LINE, TUMOR; DEXAMETHASONE; DISEASE MODELS, ANIMAL; GENE THERAPY; GENE TRANSFER TECHNIQUES; HEK293 CELLS; HEME OXYGENASE-1; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-6; MALE; MICE; MICELLES; OLIGOPEPTIDES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84857922008     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.11.001     Document Type: Article

References (82)

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2. S. Han, R.I. Mahato, Y.K. Sung, and S.W. Kim Development of biomaterials for gene therapy Mol. Ther. 2 2000 302 317
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33. Y.L. Tang, K. Qian, Y.C. Zhang, L. Shen, and M.I. Phillips A vigilant, hypoxia-regulated heme oxygenase-1 gene vector in the heart limits cardiac injury after ischemia-reperfusion in vivo J. Cardiovasc. Pharmacol. Ther. 10 2005 251 263 (Pubitemid 43003335)
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40. H. Hyun, Y.W. Won, K.M. Kim, J. Lee, M. Lee, and Y.H. Kim Therapeutic effects of a reducible poly (oligo-D-arginine) carrier with the heme oxygenase-1 gene in the treatment of hypoxic-ischemic brain injury Biomaterials 31 2010 9128 9134
41. M. Lee, J. Rentz, S.O. Han, D.A. Bull, and S.W. Kim Water-soluble lipopolymer as an efficient carrier for gene delivery to myocardium Gene Ther. 10 2003 585 593 (Pubitemid 36432610)
42. H.C. Kang, M. Lee, and Y.H. Bae Polymeric gene carriers Crit. Rev. Eukaryot. Gene Expr. 15 2005 317 342
43. S. Han, R.I. Mahato, Y.K. Sung, and S.W. Kim Development of biomaterials for gene therapy Mol. Ther. 2 2000 302 317
44. M. Lee, and S.W. Kim Polymeric gene carriers Pharm News 9 2002 407 415 (Pubitemid 37107970)
45. M.S. Wadhwa, W.T. Collard, R.C. Adami, D.L. McKenzie, and K.G. Rice Peptide-mediated gene delivery: influence of peptide structure on gene expression Bioconjug. Chem. 8 1997 81 88 (Pubitemid 27064227)
46. S. Futaki, T. Suzuki, W. Ohashi, T. Yagami, S. Tanaka, K. Ueda, and Y. Sugiura Arginine-rich peptides. An abundant source of membrane-permeable peptides having potential as carriers for intracellular protein delivery J. Biol. Chem. 276 2001 5836 5840
47. A. Kichler, A.J. Mason, and B. Bechinger Cationic amphipathic histidine-rich peptides for gene delivery Biochim. Biophys. Acta 1758 2006 301 307
48. D. Balicki, R.A. Reisfeld, U. Pertl, E. Beutler, and H.N. Lode Histone H2A-mediated transient cytokine gene delivery induces efficient antitumor responses in murine neuroblastoma Proc Natl Acad Sci USA 97 2000 11500 11504
49. D. Balicki, C.D. Putnam, P.V. Scaria, and E. Beutler Structure and function correlation in histone H2A peptide-mediated gene transfer Proc Natl Acad Sci USA 99 2002 7467 7471 (Pubitemid 34568714)
50. I. Puebla, S. Esseghir, A. Mortlock, A. Brown, A. Crisanti, and W. Low A recombinant H1 histone-based system for efficient delivery of nucleic acids J. Biotechnol. 105 2003 215 226 (Pubitemid 37315764)
51. M. Kaouass, R. Beaulieu, and D. Balicki Histonefection: novel and potent non-viral gene delivery J. Control. Release 113 2006 245 254 (Pubitemid 43983040)
52. K.M. Wagstaff, D.J. Glover, D.J. Tremethick, and D.A. Jans Histone-mediated transduction as an efficient means for gene delivery Mol. Ther. 15 2007 721 731 (Pubitemid 46431992)
53. A. Sloots, and W.S. Wels Recombinant derivatives of the human high-mobility group protein HMGB2 mediate efficient nonviral gene delivery FEBS J. 272 2005 4221 4236 (Pubitemid 41160928)
54. K. Kim, J.S. Han, H.A. Kim, and M. Lee Expression, purification and characterization of TAT-high mobility group box-1A peptide as a carrier of nucleic acids Biotechnol. Lett. 30 2008 1331 1337
55. J.S. Han, K. Kim, and M. Lee A high mobility group B-1 box A peptide combined with an artery wall binding peptide targets delivery of nucleic acids to smooth muscle cells J. Cell. Biochem. 107 2009 163 170
56. Y. Shen, H. Peng, J. Deng, Y. Wen, X. Luo, S. Pan, C. Wu, and M. Feng High mobility group box 1 protein enhances polyethylenimine mediated gene delivery in vitro Int. J. Pharm. 375 2009 140 147
57. D. Fischer, T. Bieber, Y. Li, H.P. Elsasser, and T. Kissel A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity Pharm. Res. 16 1999 1273 1279 (Pubitemid 29393618)
58. D.W. Ryu, H.A. Kim, H. Song, S. Kim, and M. Lee Amphiphilic peptides with arginines and valines for the delivery of plasmid DNA J. Cell. Biochem. 112 2011 1458 1466
59. I.M. Adcock, and G. Caramori Cross-talk between pro-inflammatory transcription factors and glucocorticoids Immunol. Cell Biol. 79 2001 376 384 (Pubitemid 32744283)
60. J.S. Choi, K.S. Ko, J.S. Park, Y.H. Kim, S.W. Kim, and M. Lee Dexamethasone conjugated poly(amidoamine) dendrimer as a gene carrier for efficient nuclear translocation Int. J. Pharm. 320 2006 171 178 (Pubitemid 44128720)
61. Y.M. Bae, H. Choi, S. Lee, S.H. Kang, K. Nam, Y.T. Kim, K. Nam, J.S. Park, M. Lee, and J.S. Choi Dexamethasone-conjugated low molecular weight polyethylenimine as a nucleus targeting lipopolymer gene carrier Bioconjug. Chem. 18 2007 2029 2036 (Pubitemid 350220005)
62. H. Kim, H.A. Kim, Y.M. Bae, J.S. Choi, and M. Lee Dexamethasone- conjugated polyethylenimine as an efficient gene carrier with an anti-apoptotic effect to cardiomyocytes J. Gene Med. 11 2009 515 522
63. H. Hyun, J. Lee, W. Hwang do, S. Kim, D.K. Hyun, J.S. Choi, J.K. Lee, and M. Lee Combinational therapy of ischemic brain stroke by delivery of heme oxygenase-1 gene and dexamethasone Biomaterials 32 2011 306 315
64. V. Shahin, L. Albermann, H. Schillers, L. Kastrup, C. Schafer, Y. Ludwig, C. Stock, and H. Oberleithner Steroids dilate nuclear pores imaged with atomic force microscopy J. Cell. Physiol. 202 2005 591 601 (Pubitemid 40041330)
65. S.C. Fagan, D.C. Hess, E.J. Hohnadel, D.M. Pollock, and A. Ergul Targets for vascular protection after acute ischemic stroke Stroke 35 2004 2220 2225 (Pubitemid 39129589)
66. J.B. Kim, J. Sig Choi, Y.M. Yu, K. Nam, C.S. Piao, S.W. Kim, M. Lee, P.L. Han, J.S. Park, and J.K. Lee HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain J. Neurosci. 26 2006 6413 6421 (Pubitemid 44318322)
67. U.I. Tuor, C.S. Simone, J.D. Barks, and M. Post Dexamethasone prevents cerebral infarction without affecting cerebral blood flow in neonatal rats Stroke 24 1993 452 457 (Pubitemid 23070054)
68. C.C. Liu, C.H. Chien, and M.T. Lin Glucocorticoids reduce interleukin-1 concentration and result in neuroprotective effects in rat heatstroke J. Physiol. 527 Pt 2 2000 333 343
69. S. Zausinger, T. Westermaier, N. Plesnila, H.J. Steiger, and R. Schmid-Elsaesser Neuroprotection in transient focal cerebral ischemia by combination drug therapy and mild hypothermia: comparison with customary therapeutic regimen Stroke 34 2003 1526 1532 (Pubitemid 36693529)
70. C.N. Chang, J.T. Yang, T.H. Lee, W.C. Cheng, Y.H. Hsu, and J.H. Wu Dexamethasone enhances upregulation of nerve growth factor mRNA expression in ischemic rat brain J. Clin. Neurosci. 12 2005 680 684 (Pubitemid 41196138)
71. N. Panahian, M. Yoshiura, and M.D. Maines Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice J. Neurochem. 72 1999 1187 1203 (Pubitemid 29085035)
72. S.F. Yet, R. Tian, M.D. Layne, Z.Y. Wang, K. Maemura, M. Solovyeva, B. Ith, L.G. Melo, L. Zhang, J.S. Ingwall, V.J. Dzau, M.E. Lee, and M.A. Perrella Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice Circ. Res. 89 2001 168 173 (Pubitemid 34135825)
73. Y.L. Tang, Y. Tang, Y.C. Zhang, K. Qian, L. Shen, and M.I. Phillips Protection from ischemic heart injury by a vigilant heme oxygenase-1 plasmid system Hypertension 43 2004 746 751 (Pubitemid 38405581)
74. Y.L. Tang, K. Qian, Y.C. Zhang, L. Shen, and M.I. Phillips A vigilant, hypoxia-regulated heme oxygenase-1 gene vector in the heart limits cardiac injury after ischemia-reperfusion in vivo J. Cardiovasc. Pharmacol. Ther. 10 2005 251 263 (Pubitemid 43003335)
75. T. Takahashi, H. Shimizu, H. Morimatsu, K. Inoue, R. Akagi, K. Morita, and S. Sassa Heme oxygenase-1: a fundamental guardian against oxidative tissue injuries in acute inflammation Mini Rev. Med. Chem. 7 2007 745 753 (Pubitemid 47099174)
76. S.H. Jung, J.E. Lee, H. Seong, and B.C. Shin Preparation of lipid nanosphere by varying species and ratio of lipid J Kor Chem Soc 50 2006 464 470
77. C.X. Song, V. Labhasetwar, H. Murphy, X. Qu, W.R. Humphrey, R.J. Shebuski, and R.J. Levy Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery J. Control. Release 43 1997 197 212 (Pubitemid 26390968)
78. L. Zhang, Y. Li, C. Zhang, Y. Wang, and C. Song Pharmacokinetics and tolerance study of intravitreal injection of dexamethasone-loaded nanoparticles in rabbits Int. J. Nanomedicine 4 2009 175 183
79. L. Sheihet, R.A. Dubin, D. Devore, and J. Kohn Hydrophobic drug delivery by self-assembling triblock copolymer-derived nanospheres Biomacromolecules 6 2005 2726 2731 (Pubitemid 41388286)
80. M. Lee, J.W. Nah, Y. Kwon, J.J. Koh, K.S. Ko, and S.W. Kim Water-soluble and low molecular weight chitosan-based plasmid DNA delivery Pharm. Res. 18 2001 427 431 (Pubitemid 32592572)
81. H. Hyun, Y.W. Won, K.M. Kim, J. Lee, M. Lee, and Y.H. Kim Therapeutic effects of a reducible poly (oligo-D-arginine) carrier with the heme oxygenase-1 gene in the treatment of hypoxic-ischemic brain injury Biomaterials 31 2010 9128 9134
82. M. Lee, J. Rentz, S.O. Han, D.A. Bull, and S.W. Kim Water-soluble lipopolymer as an efficient carrier for gene delivery to myocardium Gene Ther. 10 2003 585 593 (Pubitemid 36432610)