Dexamethasone enhances upregulation of nerve growth factor mRNA expression in ischemic rat brain

Journal of Clinical Neuroscience

Volumn 12, Issue 6, 2005, Pages 680-684

  Chang, Chen Nen ^a   Yang, Jen Tsung ^b   Lee, Tsong Hai ^a   Cheng, Wan Chun ^c   Hsu, Yung Hsin ^a   Wu, June H ^d  

^a Chang Gung Memorial Hospital   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c Tsu Ai General Hospital   (Taiwan)

^d CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

Dexamethasone; Forebrain ischemia; Hippocampus; Immunohistochemistry; in situ hybridization; Nerve growth factor

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; MESSENGER RNA; NERVE GROWTH FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN ISCHEMIA; BRAIN REGION; CONTROLLED STUDY; CORRELATION ANALYSIS; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; NERVE CELL PLASTICITY; NERVE POTENTIAL; NERVOUS SYSTEM DEVELOPMENT; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SHAM FEEDING; UPREGULATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; DEXAMETHASONE; DISEASE MODELS, ANIMAL; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; ISCHEMIA; MALE; NERVE GROWTH FACTOR; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION; RNA, MESSENGER; TIME FACTORS; UP-REGULATION;

EID: 23944479159     PISSN: 09675868     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jocn.2005.05.004     Document Type: Article

References (33)

1. N. Rocamora, M. Pascual, L. Acsady, L. de Lecea, T.F. Freund, and E. Soriano Expression of NGF and NT3 mRNAs in hippocampal interneurons innervated by the GABAergic septohippocampal pathway J Neurosci 16 1996 3991 4004
2. T. Shigeno, T. Mima, and K. Takakura Amelioration of delayed neuronal death in the hippocampus by nerve growth factor J Neurosci 11 1991 2914 2919
3. M.P. Mattson, and B. Cheng Growth factors protect neurons against excitotoxic/ischemic damage by stabilizing calcium homeostasis Stroke 24 1993 1136 1140
4. A. Takeda, H. Onodera, A. Sugimoto, K. Kogure, M. Obinata, and S. Shibahara Coordinated expression of messenger RNAs for nerve growth factor, brain-derived neurotrophic factor and neurotrophin-3 in the rat hippocampus following transient forebrain ischemia Neuroscience 55 1993 23 31
5. I. Semkova, P. Wolz, M. Schilling, and J. Krieglstein Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage Euro J Pharmacol 315 1996 19 30
6. W.A. Pulsinelli, and J.B. Brierley A new model of bilateral hemispheric ischemia in the unanesthetized rat Stroke 10 1979 267 272
7. J.T. Yang, C.N. Chang, T.H. Lee, J.C. Hsu, T.N. Lin, and J.H. Wu Dexamethasone inhibits ischemia-induced transient reduction of neurotrophin-3 mRNA in rat hippocampal neurons NeuroReport 9 1998 3477 3480
8. M.S. Saporito, E.R. Brown, and K.C. Hartpence Systemic dexamethasone administration increases septal trk autophosphorylation in adult rats via an induction of nerve growth factor Mol Pharmacol 45 1994 395 401
9. D.M. Simmons, J.L. Arriza, and L.W. Swanson A complete protocol for in situ hybridization of messenger RNAs in brain and other tissues with radio-labeled single-stranded RNA probes J Histotech 12 1989 169 181
10. T.N. Lin, J.J. Chen, and S.J. Wang Expression of NGF I-B mRNA in a rat focal cerebral ischemia-reperfusion model Mol Brain Res 43 1996 149 156
11. 1 neurons J Neurosci Res 41 1995 684 695
12. K. Yoshida, and F.H. Gage Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines Brain Res 569 1992 14 25
13. S.A. Lipton, and P.A. Rosenberg Excitatory amino acids as a final common pathway for neurologic disorders N Engl J Med 330 1994 613 622
14. R. Levi-Montalcini, and V. Hamburger Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo J Exp Zool 116 1951 321 361
15. F.H. Gage, D.M. Armstrong, L.R. Williams, and S. Varon Morphological response of axotomized septal neurons to nerve growth factor J Comp Neurol 269 1988 147 155
16. H. Ishimaru, A. Takahashi, Y. Ikarashi, and Y. Maruyama NGF delays rather than prevents the cholinergic terminal damage and delayed neuronal death in the hippocampus after ischemia Brain Res 789 1998 194 200
17. C. Guegan, I. Ceballos-Picot, E. Chevalier, A. Nicole, B. Onteniente, and B. Sola Reduction of ischemic damage in NGF-transgenic mice: correlation with enhancement of antioxidant enzyme activities Neurobiol Disease 6 1999 180 189
18. M.J.M. Schaaf, R.W.M. Hoetelmans, E.R. de Kloet, and E. Vreugdenhil Corticosterone regulates expression of BDNF and trkB but not NT-3 and trkC mRNA in the rat hippocampus J Neurosci Res 48 1997 334 341
19. M.B. Bracken, M.J. Shepard, and W.F. Collins A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal cord injury N Engl J Med 322 1990 1405 1411
20. C. Brandoli, B. Shi, B. Pflug, P. Andrews, J.R. Wrathall, and I. Mocchetti Dexamethasone reduces the expression of p75 neurotrophin receptor and apoptosis in contused spinal cord Brain Res 87 2001 61 70
21. B.S. McEwen, and E. Gould Adrenal steroid influences on the survival of hippocampal neurons Biochem Pharmacol 40 1990 2393 2402
22. S. Tsubota, N. Adachi, J. Chen, T. Yorozuya, T. Nagaro, and T. Arai Dexamethasone changes brain monoamine metabolism and aggravates ischemic neuronal damage in rats Anesthesiol 90 1999 515 523
23. V.L. Smith-Swintosky, L.C. Pettigrew, and R.M. Sapolsky Metyrapone, an inhibitor of glucocorticoid production, reduces brain injury induced by focal and global ischemia and seizures J Cereb Blood Flow Metab 16 1996 585 598
24. H.J. Krugers, S. Maslam, S.M. Van Vuuren, J. Korf, and M. Joels Postischemic steroid modulation: effects on hippocampal neuronal integrity and synaptic plasticity J Cereb Blood Flow Metab 19 1999 1072 1082
25. A. Macaya, F. Munell, I. Ferrer, C. de Torres, and J. Reventos Cell death and associated c-jun induction in perinatal hypoxia-ischemia. Effect of the neuroprotective drug dexamethasone Brain Res 56 1998 29 37
26. R. Bertorelli, M. Adami, E. Di Santo, and P. Ghezzi MK 801 and dexamethasone reduce both tumor necrosis factor levels and infarct volume after focal cerebral ischemia in the rat brain Neurosci Lett 246 1998 41 44
27. U.I. Tuor, K.L. Malisza, and P. Kozlowski Prevention of both T2- and diffusion-weighted increases in image intensity during cerebral hypoxia-ischemia in infant rats pretreated with dexamethasone Exp Brain Res 125 1999 217 220
28. J.D.E. Barks, M. Post, and U.I. Tuor Dexamethasone prevents hypoxic-ischemic brain damage in the neonatal rat Pediatr Res 29 1991 558 563
29. P. Ekert, N. MacLusky, and X.P. Luo Dexamethasone prevents apoptosis in a neonatal rat model of hypoxic-ischemic encephalopathy (HIE) by a reactive oxygen species-independent mechanism Brain Res 747 1997 9 17
30. U.I. Tuor Glucocorticoids and the prevention of hypoxic-ischemic brain damage Neurosci Biobehavioral Rev 21 1997 175 179
31. G. Barbany, and H. Persson Regulation of neurotrophin mRNA expression in the rat brain by glucocorticoids Eur J Neurosci 4 1992 396 403
32. J.T. Yang, C.N. Chang, and T.H. Lee Effect of dexamethasone on the expression of brain-derived neurotrophic factor and neurotrophin-3 messenger ribonucleic acid after forebrain ischemia in the rat Crit Care Med 30 2002 913 918
33. J.T. Yang, C.N. Chang, and T.H. Lee Hyperbaric oxygen treatment decreases postischemic neurotrophin-3 mRNA down-regulation in the rat hippocampus NeuroReport 12 2001 3589 3592