Effect of alcoholic extract of nigella sativa on cisplatininduced toxicity in rat

Iranian Journal of Kidney Diseases

Volumn 6, Issue 2, 2012, Pages 99-104

  Hadjzadeh, Mousa Al Reza ^a   Keshavarzi, Zakieh ^a   Yazdi, Seyed Abbas Tabatabaee ^b   Shirazi, Mohsen Ghasem ^a   Rajaei, Ziba ^a   Rad, Abolfazl Khajavi ^a  

^a MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b MASHHAD UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Acute kidney injury; Cisplatin; Kidney function tests; Nigella sativa

Indexed keywords

ALCOHOL; CISPLATIN; CREATININE; GLUCOSE; NIGELLA SATIVA EXTRACT; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BLACK CUMIN; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFICACY; GLUCOSE URINE LEVEL; HISTOPATHOLOGY; MALE; NEPHROTOXICITY; NONHUMAN; PLANT SEED; RAT; RENAL PROTECTION; TREATMENT RESPONSE; TRIACYLGLYCEROL BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL;

ANIMALS; ANTINEOPLASTIC AGENTS; CISPLATIN; CREATININE; ETHANOL; GLYCOSURIA; KIDNEY DISEASES; MALE; NIGELLA SATIVA; PHYTOTHERAPY; PLANT EXTRACTS; RATS; SEEDS; TRIGLYCERIDES;

EID: 84857848383     PISSN: 17358582     EISSN: 17358604     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Pannu N, Nadim MK. An overview of drug-induced acute kidney injury. Crit Care Med. 2008;36:S216-23.
2. Oh DJ, Dursun B, He Z, et al. Fractalkine receptor (CX3CR1) inhibition is protective against ischemic acute renal failure in mice. Am J Physiol Renal Physiol. 2008;294:F264-71.
3. Salem ML. Immunomodulatory and therapeutic properties of the Nigella sativa L. seed. Int Immunopharmacol. 2005;5:1749-70.
4. el Tahir KE, Ashour MM, al-Harbi MM. The respiratory effects of the volatile oil of the black seed (Nigella sativa) in guinea-pigs: elucidation of the mechanism(s) of action. Gen Pharmacol. 1993;24:1115-22.
5. El-Kadi A, Kandil O. The black seed (Nigella sativa) and immunity: its effect on human T cell subset. Fed Proc. 1987;46:1222-6
6. Hanafy MS, Hatem ME. Studies on the antimicrobial activity of Nigella sativa seed (black cumin). J Ethnopharmacol. 1991;34:275-8.
7. Zaoui A, Cherrah Y, Lacaille-Dubois MA, Settaf A, Amarouch H, Hassar M. [Diuretic and hypotensive effects of Nigella sativa in the spontaneously hypertensive rat]. Therapie. 2000;55:379-82. French.
8. Kanter M, Coskun O, Korkmaz A, Oter S. Effects of Nigella sativa on oxidative stress and beta-cell damage in streptozocin-induced diabetic rats. Anat Rec A Discov Mol Cell Evol Biol. 2004;279:685-91.
9. Kanter M, Coskun O, Budancamanak M. Hepatoprotective effects of Nigella sativa L and Urtica dioica L on lipid peroxidation, antioxidant enzyme systems and liver enzymes in carbon tetrachloride-treated rats. World J Gastroenterol. 2005;11:6684-8.
10. Kanter M, Demir H, Karakaya C, Ozbek H. Gastroprotective activity of Nigella sativa L oil and its constituent, thymoquinone against acute alcohol-induced gastric mucosal injury in rats. World J Gastroenterol. 2005;11:6662-6.
11. Hadjzadeh MA, Khoei A, Hadjzadeh Z, Parizady M. Ethanolic extract of nigella sativa L seeds on ethylene glycol-induced kidney calculi in rats. Urol J. 2007;4:86-90.
12. Kanter M, Coskun O, Uysal H. The antioxidative and antihistaminic effect of Nigella sativa and its major constituent, thymoquinone on ethanol-induced gastric mucosal damage. Arch Toxicol. 2006;80:217-24.
13. Kanter M, Coskun O, Kalayci M, Buyukbas S, Cagavi F. Neuroprotective effects of Nigella sativa on experimental spinal cord injury in rats. Hum Exp Toxicol. 2006;25: 127-33. 14. Mahfouz M, El-Dakhakhny M. The isolation of a crystalline active principle from Nigella sativa L. seeds. J Pharm Sci UAR. 1960;1:9-19.
14. Houghton PJ, Zarka R, de las Heras B, Hoult JR. Fixed oil of Nigella sativa and derived thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation. Planta Med. 1995;61:33-6.
15. Badary OA, Nagi MN, al-Shabanah OA, al-Sawaf HA, al-Sohaibani MO, al-Bekairi AM. Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity. Can J Physiol Pharmacol. 1997;75:1356-61.
16. Al-Gharably M, Badary OA, Nagi MN, et al. Protective effect of thymoquinone against carbon tetrachlorideinduced hepatotoxicity in mice. Res Commun Pharmacol Toxicol. 1997;2:41-50.
17. Budancamanak M, Kanter M, Demirel A, Ocakci A, Uysal H, Karakaya C. Protective effects of thymoquinone and methotrexate on the renal injury in collagen-induced arthritis. Arch Toxicol. 2006;80:768-76.
18. Fararh KM, Atoji Y, Shimizu Y, Takewaki T. Isulinotropic properties of Nigella sativa oil in Streptozotocin plus Nicotinamide diabetic hamster. Res Vet Sci. 2002;73: 279-82.
19. Bayrak O, Bavbek N, Karatas OF, et al. Nigella sativa protects against ischaemia/reperfusion injury in rat kidneys. Nephrol Dial Transplant. 2008;23:2206-12.
20. Faubel S, Lewis EC, Reznikov L, et al. Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1beta, IL-18, IL-6, and neutrophil infiltration in the kidney. J Pharmacol Exp Ther. 2007;322:8-15.
21. Zaoui A, Cherrah Y, Mahassini N, Alaoui K, Amarouch H, Hassar M. Acute and chronic toxicity of Nigella sativa fixed oil. Phytomedicine. 2002;9:69-74.
22. Salim EI, Fukushima S. Chemopreventive potential of volatile oil from black cumin (Nigella sativa L.) seeds against rat colon carcinogenesis. Nutr Cancer. 2003;45:195-202.
23. Mansour MA, Ginawi OT, El-Hadiyah T, El-Khatib AS, Al-Shabanah OA, Al-Sawaf HA. Effects of volatile oil constituents of Nigella sativa on carbon tetrachlorideinduced hepatotoxicity in mice: evidence for antioxidant effects of thymoquinone. Res Commun Mol Pathol Pharmacol. 2001;110:239-51.
24. Badary OA, Abdel-Naim AB, Abdel-Wahab MH, Hamada FM. The influence of thymoquinone on doxorubicininduced hyperlipidemic nephropathy in rats. Toxicology. 2000;143:219-26.
25. Khan N, Sharma S, Sultana S. Nigella sativa (black cumin) ameliorates potassium bromate-induced early events of carcinogenesis: diminution of oxidative stress. Hum Exp Toxicol. 2003;22:193-203.
26. Ramadan MF, Kroh LW, Morsel JT. Radical scavenging activity of black cumin (Nigella sativa L.), coriander (Coriandrum sativum L.), and niger (Guizotia abyssinica Cass.) crude seed oils and oil fractions. J Agric Food Chem. 2003;51:6961-9.
27. Mansour M, Tornhamre S. Inhibition of 5-lipoxygenase and leukotriene C4 synthase in human blood cells by thymoquinone. J Enzyme Inhib Med Chem. 2004;19: 431-6.
28. Maliakel DM, Kagiya TV, Nair CK. Prevention of cisplatininduced nephrotoxicity by glucosides of ascorbic acid and alpha-tocopherol. Exp Toxicol Pathol. 2008;60:521-7.
29. Ali BH, Blunden G. Pharmacological and toxicological properties of Nigella sativa. Phytother Res. 2003;17: 299-305.
30. el Daly ES. Protective effect of cysteine and vitamin E, Crocus sativus and Nigella sativa extracts on cisplatininduced toxicity in rats. J Pharm Belg. 1998;53:87-93; discussion-5.
31. Ali BH. The effect of Nigella sativa oil on gentamicin nephrotoxicity in rats. Am J Chin Med. 2004;32:49-55.