MicroRNA regulation of smooth muscle phenotype

Molecular and Cellular Pharmacology

Volumn 4, Issue 1, 2012, Pages 1-16

  Joshi, Sachindra R ^a   Comer, Brian S ^a   Mclendon, Jared M ^a   Gerthoffer, William T ^a  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

Author keywords

Asthma; Atherosclerosis; Hypertension; KLF4; Myocardin; Translation; Vascular injury; Vascular remodeling

Indexed keywords

ANTAGOMIR; CYTOSKELETON PROTEIN; DEXAMETHASONE; GAMMA INTERFERON; GLUCOCORTICOID; INTERLEUKIN 13; INTERLEUKIN 1BETA; KRUPPEL LIKE FACTOR 4; KRUPPEL LIKE FACTOR 5; MICRORNA; MICRORNA 1 133A; MICRORNA 10A; MICRORNA 143 145; MICRORNA 145; MICRORNA 146A; MICRORNA 155; MICRORNA 21; MICRORNA 25; MYOCARDIN; SERUM RESPONSE FACTOR; SMALL UNTRANSLATED RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; ATHEROSCLEROSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; ENZYME INHIBITION; FEEDBACK SYSTEM; GENE SILENCING; HUMAN; HYPERPLASIA; MUSCLE DEVELOPMENT; MUSCLE HYPERTROPHY; NEOINTIMA; NONHUMAN; PHENOTYPE; PLASTICITY; POSITIVE FEEDBACK; PROTEIN EXPRESSION; PULMONARY HYPERTENSION; RESPIRATORY TRACT DISEASE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SMOOTH MUSCLE; SMOOTH MUSCLE FIBER; TREATMENT RESPONSE; VASCULAR DISEASE; VASCULAR SMOOTH MUSCLE;

ANIMALIA;

EID: 84857830956     PISSN: None     EISSN: 19381247     Source Type: Journal    
DOI: 10.4255/mcpharmacol.12.01     Document Type: Article

References (84)

1. Richter A, Puddicombe SM, Lordan JL et al. The contribution of interleukin (IL)-4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma. Am J Respir Cell Mol Biol 2001;25:385-391.
2. Wicks J, Haitchi HM, Holgate ST, Davies DE, Powell RM. Enhanced upregulation of smooth muscle related transcripts by TGF beta2 in asthmatic (myo) fibroblasts. Thorax 2006;61:313-319.
3. Finotto S, Hausding M, Doganci A et al. Asthmatic changes in mice lacking T-bet are mediated by IL-13. Int Immunol 2005;17:993-1007.
4. Bentley JK, Hershenson MB. Airway smooth muscle growth in asthma: proliferation, hypertrophy, and migration. Proc Am Thorac Soc 2008;5:89-96.
5. McDonald OG, Owens GK. Programming smooth muscle plasticity with chromatin dynamics. Circ Res 2007;100:1428-1441.
6. Majesky MW, Dong XR, Regan JN, Hoglund VJ. Vascular smooth muscle progenitor cells: building and repairing blood vessels. Circ Res 2011;108:365-377.
7. Clifford RL, Coward WR, Knox AJ, John AE. Transcriptional regulation of inflammatory genes associated with severe asthma. Curr Pharm Des 2011;17:653-666.
8. Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 2004;84:767-801.
9. Larsson E, McLean SE, Mecham RP, Lindahl P, Nelander S. Do two mutually exclusive gene modules define the phenotypic diversity of mammalian smooth muscle? Mol Genet Genomics 2008;280:127-137.
10. Majesky MW. Developmental basis of vascular smooth muscle diversity. Arterioscler Thromb Vasc Biol 2007;27:1248-1258.
11. Eddinger TJ, Meer DP. Myosin II isoforms in smooth muscle: heterogeneity and function. Am J Physiol Cell Physiol 2007;293:C493-C508.
12. Ku G, McManus MT. Behind the scenes of a small RNA gene-silencing pathway. Hum Gene Ther 2008;19:17-26.
13. Albinsson S, Skoura A, Yu J et al. Smooth muscle miRNAs are critical for post-natal regulation of blood pressure and vascular function. PLoS One 2011;6:e18869.
14. Park C, Yan W, Ward SM et al. MicroRNAs dynamically remodel gastrointestinal smooth muscle cells. PLoS One 2011;6:e18628.
15. Ji R, Cheng Y, Yue J et al. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation. Circ Res 2007;100:1579-1588.
16. Davis BN, Hilyard AC, Lagna G, Hata A. SMAD proteins control DROSHA-mediated microRNA maturation. Nature 2008;454:56-61.
17. Cordes KR, Sheehy NT, White MP et al. miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature 2009;460:705-10.
18. Xin M, Small EM, Sutherland LB et al. MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury. Genes Dev 2009;23:2166-2178.
19. Elia L, Quintavalle M, Zhang J et al. The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease. Cell Death Differ 2009;16:1590-1598.
20. Boucher JM, Peterson SM, Urs S, Zhang C, Liaw L. The mir-143/145 cluster is a novel transcriptional target of jagged-1/notch signaling in vascular smooth muscle cells. J Biol Chem 2011;286:28312-28321
21. Cheng Y, Liu X, Yang J et al. MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation. Circ Res 2009;105:158-166.
22. Xu N, Papagiannakopoulos T, Pan G, Thomson JA, Kosik KS. MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell 2009;137:647-658.
23. Boettger T, Beetz N, Kostin S et al. Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J Clin Invest 2009;119:2634-2647.
24. Davis-Dusenbery BN, Chan MC, Reno KE et al. Downregulation of KLF4 by MIR-143/145 is critical for modulation of vascular smooth muscle cell phenotype by TGF-{beta} and BMP. J Biol Chem 2011;286:28097-28110.
25. Park C, Hennig GW, Sanders KM et al. SRF-Dependent microRNAs Regulate Gastrointestinal Smooth Muscle Cell Phenotypes. Gastroenterology 2011;141:164-75.
26. Long X, Miano JM. TGF{beta}1 utilizes distinct pathways for the transcriptional activation of microRNA 143/145 in human coronary artery smooth muscle cells. J Biol Chem 2011;286:30119-30129.
27. Sun SG, Zheng B, Han M et al. miR-146a and Kruppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation. EMBO Rep 2011;12:56-62.
28. Quintavalle M, Elia L, Condorelli G, Courtneidge SA. MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro. J Cell Biol 2010;189:13-22.
29. Hao H, Gabbiani G, Bochaton-Piallat ML. Arterial smooth muscle cell heterogeneity: implications for atherosclerosis and restenosis development. Arterioscler Thromb Vasc Biol 2003;23:1510-1520.
30. Fichtlscherer S, De RS, Fox H et al. Circulating microRNAs in patients with coronary artery disease. Circ Res 2010;107:677-684.
31. O'Sullivan JF, Martin K, Caplice NM. Microribonucleic acids for prevention of plaque rupture and in-stent restenosis: a finger in the dam. J Am Coll Cardiol 2011;57:383-389.
32. Chan MC, Hilyard AC, Wu C et al. Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression. EMBO J 2010;29:559-573.
33. Davis BN, Hilyard AC, Nguyen PH, Lagna G, Hata A. Induction of microRNA-221 by platelet-derived growth factor signaling is critical for modulation of vascular smooth muscle phenotype. J Biol Chem 2009;284:3728-3738.
34. Cardinali B, Castellani L, Fasanaro P et al. Microrna-221 and microrna-222 modulate differentiation and maturation of skeletal muscle cells. PLoS One 2009;4:e7607.
35. Liu X, Cheng Y, Zhang S, Lin Y, Yang J, Zhang C. A necessary role of miR-221 and miR-222 in vascular smooth muscle cell proliferation and neointimal hyperplasia. Circ Res 2009;104:476-487.
36. Leeper NJ, Raiesdana A, Kojima Y et al. MicroRNA-26a is a novel regulator of vascular smooth muscle cell function. J Cell Physiol 2011;226:1035-1043.
37. Mohamed JS, Lopez MA, Boriek AM. Mechanical stretch up-regulates microRNA-26a and induces human airway smooth muscle hypertrophy by suppressing glycogen synthase kinase-3beta. J Biol Chem 2010;285:29336-29347.
38. Sarkar J, Gou D, Turaka P, Viktorova E, Ramchandran R, Raj JU. MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration. Am J Physiol Lung Cell Mol Physiol 2010;299:L861-L871.
39. Ren J, Jin P, Wang E, Marincola FM, Stroncek DF. MicroRNA and gene expression patterns in the differentiation of human embryonic stem cells. J Transl Med 2009;7:20.
40. Mallanna SK, Rizzino A. Emerging roles of microRNAs in the control of embryonic stem cells and the generation of induced pluripotent stem cells. Dev Biol 2010;344:16-25.
41. Martin MM, Buckenberger JA, Jiang J et al. The human angiotensin II type 1 receptor +1166 A/C polymorphism attenuates microrna-155 binding. J Biol Chem 2007;282:24262-24269.
42. Danielson LS, Menendez S, Attolini CS et al. A differentiation-based microRNA signature identifies leiomyosarcoma as a mesenchymal stem cell-related malignancy. Am J Pathol 2010;177:908-917.
43. Zheng L, Xu CC, Chen WD et al. MicroRNA-155 regulates angiotensin II type 1 receptor expression and phenotypic differentiation in vascular adventitial fibroblasts. Biochem Biophys Res Commun 2010;400:483-488.
44. Jiang Y, Yin H, Zheng XL. MicroRNA-1 inhibits myocardin-induced contractility of human vascular smooth muscle cells. J Cell Physiol 2010;225:506-511.
45. Chen J, Yin H, Jiang Y et al. Induction of microRNA-1 by myocardin in smooth muscle cells inhibits cell proliferation. Arterioscler Thromb Vasc Biol 2011;31:368-375.
46. Xie C, Huang H, Sun X et al. MicroRNA-1 regulates smooth muscle cell differentiation by repressing Kruppel-like factor 4. Stem Cells Dev 2011;20:205-210.
47. Drab M, Haller H, Bychkov R et al. From totipotent embryonic stem cells to spontaneously contracting smooth muscle cells: a retinoic acid and db-cAMP in vitro differentiation model. FASEB J 1997;11:905-915.
48. Manabe I, Owens GK. Recruitment of serum response factor and hyperacetylation of histones at smooth muscle-specific regulatory regions during differentiation of a novel P19-derived in vitro smooth muscle differentiation system. Circ Res 2001;88:1127-1134.
49. Xie CQ, Huang H, Wei S et al. A comparison of murine smooth muscle cells generated from embryonic versus induced pluripotent stem cells. Stem Cells Dev 2009;18:741-748.
50. Huang H, Xie C, Sun X, Ritchie RP, Zhang J, Chen YE. miR-10a contributes to retinoid acid-induced smooth muscle cell differentiation. J Biol Chem 2010;285:9383-9.
51. Ellis JJ, Valencia TG, Zeng H, Roberts LD, Deaton RA, Grant SR. CaM kinase IIdeltaC phosphorylation of 14-3-3beta in vascular smooth muscle cells: activation of class II HDAC repression. Mol Cell Biochem 2003;242:153-161.
52. Yoshida T, Gan Q, Shang Y, Owens GK. Platelet-derived growth factor-BB represses smooth muscle cell marker genes via changes in binding of MKL factors and histone deacetylases to their promoters. Am J Physiol Cell Physiol 2007;292:C886-C895.
53. Ohtani K, Dimmeler S. Control of cardiovascular differentiation by microRNAs. Basic Res Cardiol 2011;106:5-11.
54. Zhang C. MicroRNA-145 in vascular smooth muscle cell biology: a new therapeutic target for vascular disease. Cell Cycle 2009;8:3469-3473.
55. Caruso P, MacLean MR, Khanin R et al. Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline. Arterioscler Thromb Vasc Biol 2010;30:716-723.
56. Courboulin A, Paulin R, Giguere NJ et al. Role for miR-204 in human pulmonary arterial hypertension. J Exp Med 2011;208:535-548.
57. Albinsson S, Sessa WC. Can microRNAs control vascular smooth muscle phenotypic modulation and the response to injury? Physiol Genomics 2011;43:529-533.
58. Zhang C. MicroRNA and vascular smooth muscle cell phenotype: new therapy for atherosclerosis? Genome Med 2009;1:85.
59. Wang S, Olson EN. AngiomiRs--key regulators of angiogenesis. Curr Opin Genet Dev 2009;19(3):205-211.
60. Wang FE, Zhang C, Maminishkis A et al. MicroRNA-204/211 alters epithelial physiology. FASEB J 2010;24:1552-1571.
61. Lee Y, Yang X, Huang Y et al. Network modeling identifies molecular functions targeted by miR-204 to suppress head and neck tumor metastasis. PLoS Comput Biol 2010;6:e1000730.
62. Chung TK, Lau TS, Cheung TH et al. Dysregulation of microRNA-204 mediates migration and invasion of endometrial cancer by regulating FOXC1. Int J Cancer 2011;130:1036-1045.
63. Zhang Y, Xie RL, Croce CM et al. A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2. Proc Natl Acad Sci U S A 2011;108:9863-8.
64. Bosse Y, Pare PD, Seow CY. Airway wall remodeling in asthma: from the epithelial layer to the adventitia. Curr Allergy Asthma Rep 2008;8:357-366.
65. Kuhn AR, Schlauch K, Lao R, Halayko AJ, Gerthoffer WT, Singer CA. MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype. Am J Respir Cell Mol Biol 2010;42:506-513.
66. Chiba Y, Tanabe M, Goto K, Sakai H, Misawa M. Down-regulation of miR-133a contributes to up-regulation of Rhoa in bronchial smooth muscle cells. Am J Respir Crit Care Med 2009;180:713-719.
67. Collison A, Mattes J, Plank M, Foster PS. Inhibition of house dust mite-induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment. J Allergy Clin Immunol 2011;128:160-176.
68. Collison A, Herbert C, Siegle JS, Mattes J, Foster PS, Kumar RK. Altered expression of microRNA in the airway wall in chronic asthma: miR-126 as a potential therapeutic target. BMC Pulm Med 2011;11:29.
69. Garbacki N, Di VE, Huynh-Thu VA et al. MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets. PLoS One 2011;6:e16509.
70. Goncharova EA, Lim PN, Chisolm A et al. Interferons modulate mitogen-induced protein synthesis in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2010;299:L25-L35.
71. Grainge CL, Lau LC, Ward JA et al. Effect of bronchoconstriction on airway remodeling in asthma. N Engl J Med 2011;364:2006-15.
72. Larner-Svensson HM, Williams AE, Tsitsiou E et al. Pharmacological studies of the mechanism and function of interleukin-1beta-induced miRNA-146a expression in primary human airway smooth muscle. Respir Res 2010;11:68.
73. Khan AA, Betel D, Miller ML, Sander C, Leslie CS, Marks DS. Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. Nat Biotechnol 2009;27:549-555.
74. Pan Q, Luo X, Chegini N. Differential expression of microRNAs in myometrium and leiomyomas and regulation by ovarian steroids. J Cell Mol Med 2008;12:227-240.
75. Bitko V, Musiyenko A, Shulyayeva O, Barik S. Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 2005;11:50-55.
76. Bitko V, Barik S. Nasal delivery of siRNA. Methods Mol Biol 2008;442:75-82.
77. Elmen J, Lindow M, Schutz S et al. LNA-mediated microRNA silencing in non-human primates. Nature 2008;452:896-899.
78. Jamaluddin MS, Weakley SM, Zhang L et al. miRNAs: roles and clinical applications in vascular disease. Expert Rev Mol Diagn 2011;11:79-89.
79. Zhang X, Azhar G, Helms SA, Wei JY. Regulation of cardiac microRNAs by serum response factor. J Biomed Sci 2011;18:15.
80. Chen JF, Mandel EM, Thomson JM et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet 2006;38:228-233.
81. Liu N, Olson EN. MicroRNA regulatory networks in cardiovascular development. Dev Cell 2010;18(4):510-525.
82. Chiba Y, Misawa M. MicroRNAs and their therapeutic potential for human diseases: MiR-133a and bronchial smooth muscle hyperresponsiveness in asthma. J Pharmacol Sci 2010;114:264-268.
83. Sachdeva M, Zhu S, Wu F et al. p53 represses c-Myc through induction of the tumor suppressor miR-145. Proc Natl Acad Sci U S A 2009;106:3207-3212.
84. Joshi SR, McLendon, JM, Comer, BS, Gerthoffer WT. MicroRNAs-control of essential genes: Implications for pulmonary vascular disease. Pulm Circ 2011;1:357-364.