Sorafenib-induced mitochondrial complex i inactivation and cell death in human neuroblastoma cells

Journal of Proteome Research

Volumn 11, Issue 3, 2012, Pages 1609-1620

  Bull, Vibeke Hervik ^a   Rajalingam, Krishnaraj ^b   Thiede, Bernd ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

apoptosis; complex I; mitochondria; neuroblastoma; SILAC; sorafenib

Indexed keywords

CASPASE; COMPLEX 1 ALPHA SUBCOMPLEX SUBUNIT 6; PROTEIN BCL 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SORAFENIB; UNCLASSIFIED DRUG;

BIOINFORMATICS; CELL COMPARTMENTALIZATION; CELL DEATH; CELL LINE; CONFERENCE PAPER; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RESPIRATORY CHAIN;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BENZENESULFONATES; CELL LINE, TUMOR; CELL SHAPE; CYTOCHROMES C; DOWN-REGULATION; ENZYME ACTIVATION; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; NADH DEHYDROGENASE; NEUROBLASTOMA; PROTEIN INTERACTION MAPS; PROTEOLYSIS; PROTEOME; PYRIDINES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE;

EID: 84857822693     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr200790e     Document Type: Conference Paper

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