Increased excitability and compromised long-term potentiation in the neocortex of NPC1 -/- mice

Brain Research

Volumn 1444, Issue , 2012, Pages 20-26

  Avchalumov, Yosef ^a   Kirschstein, Timo ^a   Lukas, Jan ^a   Luo, Jiankai ^a   Wree, Andreas ^a   Rolfs, Arndt ^a   Köhling, Rüdiger ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

CA1; Corticostriatal; Neocortex; Schaffer collateral; Synaptic plasticity; Synaptic transmission

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE; HIPPOCAMPAL CA1 REGION; LONG TERM POTENTIATION; MOUSE; NEOCORTEX; NEOSTRIATUM; NERVE EXCITABILITY; NIEMANN PICK DISEASE; NIEMANN PICK TYPE C1 GENE; NONHUMAN; PRIORITY JOURNAL; SOMATOSENSORY CORTEX;

ANIMALS; BIOPHYSICS; ELECTRIC STIMULATION; EVOKED POTENTIALS; HIPPOCAMPUS; LONG-TERM POTENTIATION; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; NEOCORTEX; PROTEINS;

ANIMALIA; MUS;

EID: 84857788738     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.01.019     Document Type: Article

References (34)

1. A. Artola, and W. Singer Long-term potentiation and NMDA receptors in rat visual cortex Nature 330 1987 649 652 (Pubitemid 18005578)
2. P. Bauer, R. Knoblich, C. Bauer, U. Finckh, A. Hufen, J. Kropp, S. Braun, B. Kustermann-Kuhn, D. Schmidt, K. Harzer, and A. Rolfs NPC1: Complete genomic sequence, mutation analysis, and characterization of haplotypes Hum. Mutat. 19 2002 30 38 (Pubitemid 34027685)
3. T.V. Bliss, and G.L. Collingridge A synaptic model of memory: long-term potentiation in the hippocampus Nature 361 1993 31 39 (Pubitemid 23020772)
4. E.D. Carstea, J.A. Morris, K.G. Coleman, S.K. Loftus, D. Zhang, C. Cummings, J. Gu, M.A. Rosenfeld, W.J. Pavan, D.B. Krizman, J. Nagle, M.H. Polymeropoulos, S.L. Sturley, Y.A. Ioannou, M.E. Higgins, M. Comly, A. Cooney, A. Brown, C.R. Kaneski, E.J. Blanchette-Mackie, N.K. Dwyer, E.B. Neufeld, T.Y. Chang, L. Liscum, J.F. Strauss III, K. Ohno, M. Zeigler, R. Carmi, J. Sokol, D. Markie, R.R. O'Neill, O.P. van Diggelen, M. Elleder, M.C. Patterson, R.O. Brady, M.T. Vanier, P.G. Pentchev, and D.A. Tagle Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis Science 277 1997 228 231 (Pubitemid 27446076)
5. L.H. Chamberlain, R.D. Burgoyne, and G.W. Gould SNARE proteins are highly enriched in lipid rafts in PC12 cells: implications for the spatial control of exocytosis Proc. Natl. Acad. Sci. U. S. A. 98 2001 5619 5624 (Pubitemid 32435691)
6. R.A. Deisz, V. Meske, S. Treiber-Held, F. Albert, and T.G. Ohm Pathological cholesterol metabolism fails to modify electrophysiological properties of afflicted neurones in Niemann-Pick disease type C Neuroscience 130 2005 867 873 (Pubitemid 40094620)
7. J.M. Dietschy, and S.D. Turley Control of cholesterol turnover in the mouse J. Biol. Chem. 277 2002 3801 3804 (Pubitemid 34968627)
8. F. Engert, and T. Bonhoeffer Dendritic spine changes associated with hippocampal long-term synaptic plasticity Nature 399 1999 66 70
9. C. Frank, S. Rufini, V. Tancredi, R. Forcina, D. Grossi, and G. D'Arcangelo Cholesterol depletion inhibits synaptic transmission and synaptic plasticity in rat hippocampus Exp. Neurol. 212 2008 407 414
10. W.S. Garver, and R.A. Heidenreich The Niemann-Pick C proteins and trafficking of cholesterol through the late endosomal/lysosomal system Curr. Mol. Med. 2 2002 485 505 (Pubitemid 34760031)
11. H. Hering, C.C. Lin, and M. Sheng Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability J. Neurosci. 23 2003 3262 3271 (Pubitemid 36531967)
12. Y. Higashi, S. Murayama, P.G. Pentchev, and K. Suzuki Cerebellar degeneration in the Niemann-Pick type C mouse Acta Neuropathol. 85 1993 175 184 (Pubitemid 23068507)
13. Ghadiri M. Khaleghi, Y. Tutam, H. Wassmann, E.J. Speckmann, and A. Gorji Periodic fasting alters neuronal excitability in rat neocortical and hippocampal tissues Neurobiol. Dis. 36 2009 384 392
14. R. Kohling, U.R. Koch, M. Hamann, and A. Richter Increased excitability in cortico-striatal synaptic pathway in a model of paroxysmal dystonia Neurobiol. Dis. 16 2004 236 245 (Pubitemid 38569814)
15. A.R. Koudinov, and N.V. Koudinova Essential role for cholesterol in synaptic plasticity and neuronal degeneration FASEB J. 15 2001 1858 1860
16. P. Li, Y.H. Li, and T.Z. Han NR2A-containing NMDA receptors are required for LTP induction in rat dorsolateral striatum in vitro Brain Res. 1274 2009 40 46
17. S. Love, L.R. Bridges, and C.P. Case Neurofibrillary tangles in Niemann-Pick disease type C Brain 118 Pt. 1 1995 119 129
18. R.C. Malenka, and M.F. Bear LTP and LTD: an embarrassment of riches Neuron 44 2004 5 21 (Pubitemid 39348827)
19. P.A. March, M.A. Thrall, D.E. Brown, T.W. Mitchell, A.C. Lowenthal, and S.U. Walkley GABAergic neuroaxonal dystrophy and other cytopathological alterations in feline Niemann-Pick disease type C Acta Neuropathol. 94 1997 164 172 (Pubitemid 27338505)
20. G. Martella, A. Tassone, G. Sciamanna, P. Platania, D. Cuomo, M.T. Viscomi, P. Bonsi, E. Cacci, S. Biagioni, A. Usiello, G. Bernardi, N. Sharma, D.G. Standaert, and A. Pisani Impairment of bidirectional synaptic plasticity in the striatum of a mouse model of DYT1 dystonia: role of endogenous acetylcholine Brain 132 2009 2336 2349
21. D. Mitter, C. Reisinger, B. Hinz, S. Hollmann, S.V. Yelamanchili, S. Treiber-Held, T.G. Ohm, A. Herrmann, and G. Ahnert-Hilger The synaptophysin/synaptobrevin interaction critically depends on the cholesterol content J. Neurochem. 84 2003 35 42 (Pubitemid 36182063)
22. P.F. Parkinson, T.S. Kannangara, B.D. Eadie, B.L. Burgess, C.L. Wellington, and B.R. Christie Cognition, learning behaviour and hippocampal synaptic plasticity are not disrupted in mice over-expressing the cholesterol transporter ABCG1 Lipids Health Dis. 8 2009 5
23. C.A. Paul, A.K. Boegle, and R.A. Maue Before the loss: neuronal dysfunction in Niemann-Pick Type C disease Biochim. Biophys. Acta 1685 2004 63 76 (Pubitemid 39311810)
24. P.G. Pentchev, A.E. Gal, A.D. Booth, F. Omodeo-Sale, J. Fouks, B.A. Neumeyer, J.M. Quirk, G. Dawson, and R.O. Brady A lysosomal storage disorder in mice characterized by a dual deficiency of sphingomyelinase and glucocerebrosidase Biochim. Biophys. Acta 619 1980 669 679 (Pubitemid 11201153)
25. L.D. Pozzo-Miller, W. Gottschalk, L. Zhang, K. McDermott, J. Du, R. Gopalakrishnan, C. Oho, Z.H. Sheng, and B. Lu Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice J. Neurosci. 19 1999 4972 4983 (Pubitemid 29270132)
26. D.P. Purpura, and K. Suzuki Distortion of neuronal geometry and formation of aberrant synapses in neuronal storage disease Brain Res. 116 1976 1 21
27. S. Rumpel, J. LeDoux, A. Zador, and R. Malinow Postsynaptic receptor trafficking underlying a form of associative learning Science 308 2005 83 88 (Pubitemid 40471002)
28. J.R. Sarna, M. Larouche, H. Marzban, R.V. Sillitoe, D.E. Rancourt, and R. Hawkes Patterned Purkinje cell degeneration in mouse models of Niemann-Pick type C disease J. Comp. Neurol. 456 2003 279 291 (Pubitemid 36110250)
29. S.M. Sparrow, J.M. Carter, N.D. Ridgway, H.W. Cook, and D.M. Byers U18666A inhibits intracellular cholesterol transport and neurotransmitter release in human neuroblastoma cells Neurochem. Res. 24 1999 69 77 (Pubitemid 29067778)
30. S.L. Sturley, M.C. Patterson, W. Balch, and L. Liscum The pathophysiology and mechanisms of NP-C disease Biochim. Biophys. Acta 1685 2004 83 87 (Pubitemid 39311812)
31. E. Taverna, E. Saba, J. Rowe, M. Francolini, F. Clementi, and P. Rosa Role of lipid microdomains in P/Q-type calcium channel (Cav2.1) clustering and function in presynaptic membranes J. Biol. Chem. 279 2004 5127 5134 (Pubitemid 38220529)
32. J.R. Whitlock, A.J. Heynen, M.G. Shuler, and M.F. Bear Learning induces long-term potentiation in the hippocampus Science 313 2006 1093 1097 (Pubitemid 44300229)
33. M. Zervas, K. Dobrenis, and S.U. Walkley Neurons in Niemann-Pick disease type C accumulate gangliosides as well as unesterified cholesterol and undergo dendritic and axonal alterations J. Neuropathol. Exp. Neurol. 60 2001 49 64 (Pubitemid 32097005)
34. Q. Zhou, K.J. Homma, and M.M. Poo Shrinkage of dendritic spines associated with long-term depression of hippocampal synapses Neuron 44 2004 749 757 (Pubitemid 39575629)