Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis

Metabolomics

Volumn 8, Issue 2, 2012, Pages 253-263

  Noga, Marek J ^a   Dane, Adrie ^a   Shi, Shanna ^a   Attali, Amos ^b   van Aken, Hans ^b   Suidgeest, Ernst ^b   Tuinstra, Tinka ^b   Muilwijk, Bas ^c   Coulier, Leon ^a,c   Luider, Theo ^d   Reijmers, Theo H ^a   Vreeken, Rob J ^a   Hankemeier, Thomas ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b Chemical Design and Synthesis Unit   (Netherlands)

^c TNO   (Netherlands)

^d ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

CSF; EAE; GC MS; LC MS; Metabolomics; Multiple sclerosis

Indexed keywords

ALANINE; ARGININE; BRANCHED CHAIN AMINO ACID; FREUND ADJUVANT; GLUTAMINE; MYELIN BASIC PROTEIN; PHOSPHOETHANOLAMINE; PUTRESCINE;

ACUTE DISEASE; ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM METABOLISM; CEREBROSPINAL FLUID; CONTROLLED STUDY; DISEASE COURSE; LIQUID CHROMATOGRAPHY; MALE; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; METABOLISM; METABOLOME; METABOLOMICS; MULTIPLE SCLEROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; RAT;

ANIMALIA; RATTUS;

EID: 84857786155     PISSN: 15733882     EISSN: 15733890     Source Type: Journal    
DOI: 10.1007/s11306-011-0306-3     Document Type: Article

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