The combined predictive capacity of rat models of algogen-induced and neuropathic hypersensitivity to clinically used analgesics varies with nociceptive endpoint and consideration of locomotor function

Pharmacology Biochemistry and Behavior

Volumn 101, Issue 3, 2012, Pages 465-478

  Munro, Gordon ^a   Storm, Ann ^a   Hansen, Merete K ^a   Dyhr, Helene ^a   Marcher, Lotte ^a   Erichsen, Helle K ^a   Sheykhzade, Majid ^b  

^a NEUROSEARCH A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Allodynia; Analgesia; Capsaicin; CCI; Central sensitization; Formalin; Hyperalgesia; Pain

Indexed keywords

CAPSAICIN; DULOXETINE; FORMALDEHYDE; GABAPENTIN; MORPHINE;

ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR DISORDER; COLD SENSITIVITY; CONTROLLED STUDY; DRUG MEGADOSE; DRUG SENSITIVITY; HYPERSENSITIVITY; INTERPHASE; LOCOMOTION; MALE; MECHANICS; MOTOR PERFORMANCE; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; WEIGHT BEARING;

AMINES; ANALGESICS; ANIMALS; CAPSAICIN; CYCLOHEXANECARBOXYLIC ACIDS; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FORMALDEHYDE; GAMMA-AMINOBUTYRIC ACID; HYPERALGESIA; LOCOMOTION; MALE; MORPHINE; NEURALGIA; PAIN; PAIN MEASUREMENT; RATS; RATS, SPRAGUE-DAWLEY; THIOPHENES;

RATTUS;

EID: 84857665853     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2012.02.008     Document Type: Article

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