메뉴 건너뛰기




Volumn 71, Issue 3, 2012, Pages 198-210

Unmyelinated axons show selective rostrocaudal pathology in the corpus callosum after traumatic brain injury

Author keywords

Axonal injury; Corpus callosum; Stereology; Traumatic brain injury; Ultrastructure; Unmyelinated axons

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AXONAL INJURY; CONTROLLED STUDY; HISTOPATHOLOGY; MALE; NONHUMAN; NONMYELINATED NERVE; PRIORITY JOURNAL; RAT; TRAUMATIC BRAIN INJURY;

EID: 84857514761     PISSN: 00223069     EISSN: 15546578     Source Type: Journal    
DOI: 10.1097/NEN.0b013e3182482590     Document Type: Article
Times cited : (60)

References (62)
  • 2
    • 77956940511 scopus 로고    scopus 로고
    • Prevalence and impact of diffuse axonal injury in patients with moderate and severe head injury: A cohort study of early magnetic resonance imaging findings and 1-year outcome
    • Skandsen T, Kvistad KA, Solheim O, et al. Prevalence and impact of diffuse axonal injury in patients with moderate and severe head injury: A cohort study of early magnetic resonance imaging findings and 1-year outcome. J Neurosurg 2010;113:556-63
    • (2010) J Neurosurg , vol.113 , pp. 556-563
    • Skandsen, T.1    Kvistad, K.A.2    Solheim, O.3
  • 3
    • 0034795510 scopus 로고    scopus 로고
    • Current concepts: Diffuse axonal injury-associated traumatic brain injury
    • Meythaler JM, Peduzzi JD, Eleftheriou E, et al. Current concepts: Diffuse axonal injury-associated traumatic brain injury. Arch Phys Med Rehabil 2001;82:1461-71
    • (2001) Arch Phys Med Rehabil , vol.82 , pp. 1461-1471
    • Meythaler, J.M.1    Peduzzi, J.D.2    Eleftheriou, E.3
  • 4
    • 49749209180 scopus 로고
    • Shearing of nerve fibers as a cause of brain damage due to head injury: A pathological study of twenty cases
    • Strich SJ. Shearing of nerve fibers as a cause of brain damage due to head injury: A pathological study of twenty cases. Lancet 1961;2:443-48
    • (1961) Lancet , vol.2 , pp. 443-448
    • Strich, S.J.1
  • 5
    • 0030752893 scopus 로고    scopus 로고
    • A mechanistic analysis of nondisruptive axonal injury: A review
    • Maxwell WL, Povlishock JT, Graham DL. A mechanistic analysis of nondisruptive axonal injury: A review. J Neurotrauma 1997;14:419-40
    • (1997) J Neurotrauma , vol.14 , pp. 419-440
    • Maxwell, W.L.1    Povlishock, J.T.2    Graham, D.L.3
  • 6
    • 0028793071 scopus 로고
    • The pathobiology of traumatically induced axonal injury in animals and humans: A review of current thoughts
    • Povlishock JT, Christman CW. The pathobiology of traumatically induced axonal injury in animals and humans: A review of current thoughts. J Neurotrauma 1995;12:555-64
    • (1995) J Neurotrauma , vol.12 , pp. 555-564
    • Povlishock, J.T.1    Christman, C.W.2
  • 7
    • 0031743865 scopus 로고    scopus 로고
    • The neuronal cytoskeleton is at risk after mild and moderate brain injury
    • Saatman KE, Graham DI, McIntosh TK. The neuronal cytoskeleton is at risk after mild and moderate brain injury. J Neurotrauma 1998;15:1047-58
    • (1998) J Neurotrauma , vol.15 , pp. 1047-1058
    • Saatman, K.E.1    Graham, D.I.2    McIntosh, T.K.3
  • 8
    • 0032860822 scopus 로고    scopus 로고
    • Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig
    • Smith DH, Chen XH, Nonaka M, et al. Accumulation of amyloid beta and tau and the formation of neurofilament inclusions following diffuse brain injury in the pig. J Neuropathol Exp Neurol 1998;58:982-92
    • (1998) J Neuropathol Exp Neurol , vol.58 , pp. 982-992
    • Smith, D.H.1    Chen, X.H.2    Nonaka, M.3
  • 9
    • 61849110362 scopus 로고    scopus 로고
    • Impaired axonal transport and neurofilament compaction occur in separate populations of injured axons following diffuse brain injury in the immature rat
    • Di Leonardi AM, Huh HW, Raghupathi R. Impaired axonal transport and neurofilament compaction occur in separate populations of injured axons following diffuse brain injury in the immature rat. Brain Res 2009;1263:174-82
    • (2009) Brain Res , vol.1263 , pp. 174-182
    • Di Leonardi, A.M.1    Huh, H.W.2    Raghupathi, R.3
  • 10
    • 0035690458 scopus 로고    scopus 로고
    • Intra-axonal neurofilament compaction does not evoke local axonal swelling in all traumatically injured axons
    • Stone JR, Singleton RH, Povlishock JT. Intra-axonal neurofilament compaction does not evoke local axonal swelling in all traumatically injured axons. Exp Neurol 2001;172:320-31
    • (2001) Exp Neurol , vol.172 , pp. 320-331
    • Stone, J.R.1    Singleton, R.H.2    Povlishock, J.T.3
  • 11
    • 30444454199 scopus 로고    scopus 로고
    • Administration of the immunophilin ligand FK506 differentially attenuates neurofilament compaction and impaired axonal transport in injured axons following diffuse traumatic brain injury
    • Marmarou CR, Povlishock JT. Administration of the immunophilin ligand FK506 differentially attenuates neurofilament compaction and impaired axonal transport in injured axons following diffuse traumatic brain injury. Exp Neurol 2006;197:353-62
    • (2006) Exp Neurol , vol.197 , pp. 353-362
    • Marmarou, C.R.1    Povlishock, J.T.2
  • 12
    • 26244455133 scopus 로고    scopus 로고
    • Myelinated and unmyelinated axons of the corpus callosum differ in vulnerability and functional recovery following traumatic brain injury
    • Reeves TM, Phillips LL, Povlishock JT. Myelinated and unmyelinated axons of the corpus callosum differ in vulnerability and functional recovery following traumatic brain injury. Exp Neurol 2005;196:126-39
    • (2005) Exp Neurol , vol.196 , pp. 126-139
    • Reeves, T.M.1    Phillips, L.L.2    Povlishock, J.T.3
  • 13
    • 34347351104 scopus 로고    scopus 로고
    • Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury
    • Ai J, Liu E, Wang J, et al. Calpain inhibitor MDL-28170 reduces the functional and structural deterioration of corpus callosum following fluid percussion injury. J Neurotrauma 2007;24:960-78
    • (2007) J Neurotrauma , vol.24 , pp. 960-978
    • Ai, J.1    Liu, E.2    Wang, J.3
  • 14
    • 77953705443 scopus 로고    scopus 로고
    • The effects of cyclosporin-A on axonal conduction deficits following traumatic brain injury in adult rats
    • Colley BS, Phillips LL, Reeves TM. The effects of cyclosporin-A on axonal conduction deficits following traumatic brain injury in adult rats. Exp Neurol 2010;224:241-51
    • (2010) Exp Neurol , vol.224 , pp. 241-251
    • Colley, B.S.1    Phillips, L.L.2    Reeves, T.M.3
  • 15
    • 34249856764 scopus 로고    scopus 로고
    • Preferential neuroprotective effect of tacrolimus (FK506) on unmyelinated axons following traumatic brain injury
    • Reeves TM, Phillips LL, Povlishock JT. Preferential neuroprotective effect of tacrolimus (FK506) on unmyelinated axons following traumatic brain injury. Brain Res 2007;1154:225-36
    • (2007) Brain Res , vol.1154 , pp. 225-236
    • Reeves, T.M.1    Phillips, L.L.2    Povlishock, J.T.3
  • 16
    • 0036267103 scopus 로고    scopus 로고
    • Attenuation of the electrophysiological function of the corpus callosum after fluid percussion injury in the rat
    • Baker AJ, Phan N, Moulton RJ, et al. Attenuation of the electrophysiological function of the corpus callosum after fluid percussion injury in the rat. J Neurotrauma 2002;19:587-99
    • (2002) J Neurotrauma , vol.19 , pp. 587-599
    • Baker, A.J.1    Phan, N.2    Moulton, R.J.3
  • 17
    • 79953822054 scopus 로고    scopus 로고
    • Concussive brain trauma in the mouse results in acute cognitive deficits and sustained impairment of axonal function
    • Creed JA, Di Leonardi AM, Fox DP, et al. Concussive brain trauma in the mouse results in acute cognitive deficits and sustained impairment of axonal function. J Neurotrauma 2011;28:547-63
    • (2011) J Neurotrauma , vol.28 , pp. 547-563
    • Creed, J.A.1    Di Leonardi, A.M.2    Fox, D.P.3
  • 18
    • 12544255943 scopus 로고    scopus 로고
    • Lateral fluid percussion brain injury: A 15-year review and evaluation
    • Thompson HJ, Lifshitz J, Marklund N, et al. Lateral fluid percussion brain injury: A 15-year review and evaluation. J Neurotrauma 2005;22:42-75
    • (2005) J Neurotrauma , vol.22 , pp. 42-75
    • Thompson, H.J.1    Lifshitz, J.2    Marklund, N.3
  • 19
    • 79953661325 scopus 로고    scopus 로고
    • Animal models of traumatic brain injury: A critical evaluation
    • O'Connor WT, Smyth A, Gilchrist MD. Animal models of traumatic brain injury: A critical evaluation. Pharmacol Ther 2011;130:106-13
    • (2011) Pharmacol Ther , vol.130 , pp. 106-113
    • O'Connor, W.T.1    Smyth, A.2    Gilchrist, M.D.3
  • 20
    • 0025002707 scopus 로고
    • Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat
    • Lyeth BG, Jenkins LW, Hamm RJ, et al. Prolonged memory impairment in the absence of hippocampal cell death following traumatic brain injury in the rat. Brain Res 1990;526:249-58
    • (1990) Brain Res , vol.526 , pp. 249-258
    • Lyeth, B.G.1    Jenkins, L.W.2    Hamm, R.J.3
  • 21
    • 3442883618 scopus 로고    scopus 로고
    • The number, size, and type of axons in rat subcortical white matter on left and right sides: A stereological, ultrastructural study
    • Partadiredja G, Miller R, Oorschot DE. The number, size, and type of axons in rat subcortical white matter on left and right sides: A stereological, ultrastructural study. J Neurocytol 2003;32:1165-79
    • (2003) J Neurocytol , vol.32 , pp. 1165-1179
    • Partadiredja, G.1    Miller, R.2    Oorschot, D.E.3
  • 22
    • 0023256508 scopus 로고
    • A fluid percussion model of experimental brain injury in the rat
    • Dixon CE, Lyeth BG, Povlishock JT, et al. A fluid percussion model of experimental brain injury in the rat. J Neurosurg 1987;67:110-19
    • (1987) J Neurosurg , vol.67 , pp. 110-119
    • Dixon, C.E.1    Lyeth, B.G.2    Povlishock, J.T.3
  • 24
    • 0032215084 scopus 로고    scopus 로고
    • Stereology of nerve cross sections
    • Larsen JO. Stereology of nerve cross sections. J Neurosci Meth 1998;85:107-18
    • (1998) J Neurosci Meth , vol.85 , pp. 107-118
    • Larsen, J.O.1
  • 25
    • 0025055296 scopus 로고
    • Maturation of the corpus callosum of the rat: II. Influence of thyroid hormones on the number and maturation of axons
    • Gravel C, Sasseville R, Hawkes R. Maturation of the corpus callosum of the rat: II. Influence of thyroid hormones on the number and maturation of axons. J Comp Neurol 1990;291:147-61
    • (1990) J Comp Neurol , vol.291 , pp. 147-161
    • Gravel, C.1    Sasseville, R.2    Hawkes, R.3
  • 26
    • 0019164102 scopus 로고
    • Myelination of the mouse corpus callosum
    • Sturrock RR. Myelination of the mouse corpus callosum. Neuropath Applied Neurobiol 1980;6:415-20
    • (1980) Neuropath Applied Neurobiol , vol.6 , pp. 415-420
    • Sturrock, R.R.1
  • 27
    • 0017168376 scopus 로고
    • Ultrastructure of visual callosal axons in the rabbit
    • Waxman SG, Swadlow HA. Ultrastructure of visual callosal axons in the rabbit. Exp Neurol 1976;53:115-27
    • (1976) Exp Neurol , vol.53 , pp. 115-127
    • Waxman, S.G.1    Swadlow, H.A.2
  • 28
    • 84944495904 scopus 로고
    • A theory of the effects of fibre size in medullated nerve
    • Rushton WA. A theory of the effects of fibre size in medullated nerve. J Physiol 1951;115:101-22
    • (1951) J Physiol , vol.115 , pp. 101-122
    • Rushton, W.A.1
  • 29
    • 0035836469 scopus 로고    scopus 로고
    • Changes in axonal physiology and morphology after chronic compressive injury of the thoracic spinal cord
    • Nashmi R, Fehlings MG. Changes in axonal physiology and morphology after chronic compressive injury of the thoracic spinal cord. Neuroscience 2001;104:235-51
    • (2001) Neuroscience , vol.104 , pp. 235-251
    • Nashmi, R.1    Fehlings, M.G.2
  • 30
    • 0014882186 scopus 로고
    • Myelinated nerve fibers: Computed effect of myelin thickness on conduction velocity
    • Smith RS, Koles ZJ. Myelinated nerve fibers: Computed effect of myelin thickness on conduction velocity. Am J Physiol 1970;219:1256-58
    • (1970) Am J Physiol , vol.219 , pp. 1256-1258
    • Smith, R.S.1    Koles, Z.J.2
  • 31
    • 0027999170 scopus 로고
    • Animate models of human head injury
    • Gennarelli TA. Animate models of human head injury. J Neurotrauma 1994;11:357-68
    • (1994) J Neurotrauma , vol.11 , pp. 357-368
    • Gennarelli, T.A.1
  • 32
    • 0028555305 scopus 로고
    • Workshop on animal models of traumatic brain injury
    • Povlishock JT, Hayes RL, Michel ME, et al. Workshop on animal models of traumatic brain injury. J Neurotrauma 1994;11:723-32
    • (1994) J Neurotrauma , vol.11 , pp. 723-732
    • Povlishock, J.T.1    Hayes, R.L.2    Michel, M.E.3
  • 33
    • 0030725073 scopus 로고    scopus 로고
    • Impact acceleration injury in the rat: Evidence for focal axolemma change and related neurofilament sidearm alteration
    • Povlishock JT, Marmarou A, McIntosh T, et al. Impact acceleration injury in the rat: Evidence for focal axolemma change and related neurofilament sidearm alteration. J Neuropathol Exp Neurol 1997;56:347-59
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 347-359
    • Povlishock, J.T.1    Marmarou, A.2    McIntosh, T.3
  • 34
    • 0033525008 scopus 로고    scopus 로고
    • Cyclosporin A limits calcium-induced axonal damage following traumatic brain injury
    • Okonkwo DO, Buki A, Siman R, Povlishock JT. Cyclosporin A limits calcium-induced axonal damage following traumatic brain injury. Neuroreport 1999;10:353-58
    • (1999) Neuroreport , vol.10 , pp. 353-358
    • Okonkwo, D.O.1    Buki, A.2    Siman, R.3    Povlishock, J.T.4
  • 35
    • 84857618146 scopus 로고    scopus 로고
    • Post-injury cyclosporin A administration limits axonal damage and disconnection in traumatic brain injury
    • Buki A, Okonkwo DO, Povlishock JT. Post-injury cyclosporin A administration limits axonal damage and disconnection in traumatic brain injury. J Neurotrauma 1999;58:365-75
    • (1999) J Neurotrauma , vol.58 , pp. 365-375
    • Buki, A.1    Okonkwo, D.O.2    Povlishock, J.T.3
  • 36
    • 0034967409 scopus 로고    scopus 로고
    • The immunophilin ligand FK506 attenuates axonal injury in an impact-acceleration model of traumatic brain injury
    • Singleton RH, Stone JR, Okonkwo DO, et al. The immunophilin ligand FK506 attenuates axonal injury in an impact-acceleration model of traumatic brain injury. J Neurotrauma 2001;18:607-14
    • (2001) J Neurotrauma , vol.18 , pp. 607-614
    • Singleton, R.H.1    Stone, J.R.2    Okonkwo, D.O.3
  • 37
    • 33644776851 scopus 로고    scopus 로고
    • A systematic review of brain injury epidemiology in Europe
    • Tagliaferri F, Compagnone C, Korsic M, et al. A systematic review of brain injury epidemiology in Europe. Acta Neurochir (Wien) 2006;148:255-68
    • (2006) Acta Neurochir (Wien) , vol.148 , pp. 255-268
    • Tagliaferri, F.1    Compagnone, C.2    Korsic, M.3
  • 38
    • 0015335673 scopus 로고
    • Ontogeny of interhemispheric evoked potentials in the rat: Significance of myelination of the corpus callosum
    • Seggie J, Berry M. Ontogeny of interhemispheric evoked potentials in the rat: Significance of myelination of the corpus callosum. Exp Neurol 1972;35:215-32
    • (1972) Exp Neurol , vol.35 , pp. 215-232
    • Seggie, J.1    Berry, M.2
  • 39
    • 0023933883 scopus 로고
    • Sex and environmental influences on the size and ultrastructure of the rat corpus callosum
    • Juraska JM, Kopcik JR. Sex and environmental influences on the size and ultrastructure of the rat corpus callosum. Brain Res 1988;450:1-8
    • (1988) Brain Res , vol.450 , pp. 1-8
    • Juraska, J.M.1    Kopcik, J.R.2
  • 40
    • 0030592816 scopus 로고    scopus 로고
    • A re-examination of sex differences in axon density and number in the splenium of the rat corpus callosum
    • Kim J H Y, Ellman A, Juraska JM. A re-examination of sex differences in axon density and number in the splenium of the rat corpus callosum. Brain Res 1996;740:47-56
    • (1996) Brain Res , vol.740 , pp. 47-56
    • Kim, J.H.Y.1    Ellman, A.2    Juraska, J.M.3
  • 41
    • 0028152764 scopus 로고
    • Traumatically induced altered membrane permeability: Its relationship to traumatically induced reactive axonal change
    • Pettus EH, Christman CW, Giebel ML, et al. Traumatically induced altered membrane permeability: Its relationship to traumatically induced reactive axonal change. J Neurotrauma 1994;11:507-22
    • (1994) J Neurotrauma , vol.11 , pp. 507-522
    • Pettus, E.H.1    Christman, C.W.2    Giebel, M.L.3
  • 42
    • 0029584859 scopus 로고
    • Cytochemical evidence for redistribution of membrane pump calcium-ATPase and ecto-Ca-ATPase activity, and calcium influx in myelinated nerve fibers of the optic nerve after stretch injury
    • Maxwell WL, McCreath BJ, Graham DI, et al. Cytochemical evidence for redistribution of membrane pump calcium-ATPase and ecto-Ca-ATPase activity, and calcium influx in myelinated nerve fibers of the optic nerve after stretch injury. J Neurocytol 1995;24:925-42
    • (1995) J Neurocytol , vol.24 , pp. 925-942
    • Maxwell, W.L.1    McCreath, B.J.2    Graham, D.I.3
  • 43
    • 0030925162 scopus 로고    scopus 로고
    • Axonal cytoskeletal changes after nondisruptive axonal injury
    • Jafari SS, Maxwell WL, Neilson M, et al. Axonal cytoskeletal changes after nondisruptive axonal injury. J Neurocytol 1997;26:207-21
    • (1997) J Neurocytol , vol.26 , pp. 207-221
    • Jafari, S.S.1    Maxwell, W.L.2    Neilson, M.3
  • 44
    • 0026435098 scopus 로고
    • Traumatically induced axonal injury: Pathogenesis and pathobiological implications
    • Povlishock JT. Traumatically induced axonal injury: Pathogenesis and pathobiological implications. Brain Pathol 1992;2:1-12
    • (1992) Brain Pathol , vol.2 , pp. 1-12
    • Povlishock, J.T.1
  • 45
    • 27444437488 scopus 로고    scopus 로고
    • Quantitative analysis of the relationship between intra-axonal neurofilament compaction and impaired axonal transport following diffuse traumatic brain injury
    • Marmarou CR, Walker S, Davis CL, et al. Quantitative analysis of the relationship between intra-axonal neurofilament compaction and impaired axonal transport following diffuse traumatic brain injury. J Neurotrauma 2005;22:1066-80
    • (2005) J Neurotrauma , vol.22 , pp. 1066-1080
    • Marmarou, C.R.1    Walker, S.2    Davis, C.L.3
  • 46
    • 0023883667 scopus 로고
    • Unmyelinated and myelinated axon membrane from rat corpus callosum: Differences in macromolecular structure
    • Waxman SG, Black JA. Unmyelinated and myelinated axon membrane from rat corpus callosum: Differences in macromolecular structure. Brain Res 1988;453:337-43
    • (1988) Brain Res , vol.453 , pp. 337-343
    • Waxman, S.G.1    Black, J.A.2
  • 47
    • 0027265381 scopus 로고
    • Free radicals in brain metabolism and pathology
    • Evans PH. Free radicals in brain metabolism and pathology. Br Med Bull 1993;49:577-87
    • (1993) Br Med Bull , vol.49 , pp. 577-587
    • Evans, P.H.1
  • 48
    • 33846196606 scopus 로고    scopus 로고
    • Role of peroxynitrite in secondary oxidative damage after spinal cord injury
    • Xiong Y, Rabchevsky AG, Hall ED. Role of peroxynitrite in secondary oxidative damage after spinal cord injury. J Neurochem 2007;100:639-49
    • (2007) J Neurochem , vol.100 , pp. 639-649
    • Xiong, Y.1    Rabchevsky, A.G.2    Hall, E.D.3
  • 49
    • 2442662940 scopus 로고    scopus 로고
    • Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors
    • Iwata A, Stys PK, Wolf JA, et al. Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors. J Neurosci 2004;24:4605-13
    • (2004) J Neurosci , vol.24 , pp. 4605-4613
    • Iwata, A.1    Stys, P.K.2    Wolf, J.A.3
  • 50
    • 69049116237 scopus 로고    scopus 로고
    • Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit
    • von Reyn CR, Spaethling JM, Mesfin MN, et al. Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit. J Neurosci 2009;29:10350-56
    • (2009) J Neurosci , vol.29 , pp. 10350-10356
    • Von Reyn, C.R.1    Spaethling, J.M.2    Mesfin, M.N.3
  • 51
    • 78449269668 scopus 로고    scopus 로고
    • Proteolysis of submembrane cytoskeletal proteins ankyrin-G and αII spectrin following diffuse brain injury: A role in white matter vulnerability at nodes of Ranvier
    • Reeves TM, Greer JE, Vanderveer AS, et al. Proteolysis of submembrane cytoskeletal proteins ankyrin-G and αII spectrin following diffuse brain injury: A role in white matter vulnerability at nodes of Ranvier. Brain Pathol 2010;20:1055-68
    • (2010) Brain Pathol , vol.20 , pp. 1055-1068
    • Reeves, T.M.1    Greer, J.E.2    Vanderveer, A.S.3
  • 52
    • 14744306422 scopus 로고    scopus 로고
    • Spatial and temporal characteristics of neurodegeneration after controlled cortical impact in nice: More than a focal brain injury
    • Hall ED, Sullivan PG, Gibson TR, et al. Spatial and temporal characteristics of neurodegeneration after controlled cortical impact in nice: More than a focal brain injury. J Neurotrauma 2005;22:252-65
    • (2005) J Neurotrauma , vol.22 , pp. 252-265
    • Hall, E.D.1    Sullivan, P.G.2    Gibson, T.R.3
  • 53
    • 0037215483 scopus 로고    scopus 로고
    • Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice
    • Saatman KE, Abai B, Grosvenor A, et al. Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice. J Cereb Blood Flow Metab 2003;23:34-42
    • (2003) J Cereb Blood Flow Metab , vol.23 , pp. 34-42
    • Saatman, K.E.1    Abai, B.2    Grosvenor, A.3
  • 54
    • 72949093813 scopus 로고    scopus 로고
    • Calpain as a therapeutic target in traumatic brain injury
    • Saatman KE, Creed J, Raghupathi R. Calpain as a therapeutic target in traumatic brain injury. Neurotherapeutics 2010;7:31-42
    • (2010) Neurotherapeutics , vol.7 , pp. 31-42
    • Saatman, K.E.1    Creed, J.2    Raghupathi, R.3
  • 55
    • 0141624363 scopus 로고    scopus 로고
    • White matter injury mechanisms
    • Stys PK. White matter injury mechanisms. Cur Mol Med 2004;4:113-30
    • (2004) Cur Mol Med , vol.4 , pp. 113-130
    • Stys, P.K.1
  • 57
    • 13444261161 scopus 로고    scopus 로고
    • Elevation of hippocampal MMP-3 expression and activity during trauma-induced synaptogenesis
    • Kim HJ, Fillmore HL, Reeves TM, et al. Elevation of hippocampal MMP-3 expression and activity during trauma-induced synaptogenesis. Exp Neurol 2005;192:60-72
    • (2005) Exp Neurol , vol.192 , pp. 60-72
    • Kim, H.J.1    Fillmore, H.L.2    Reeves, T.M.3
  • 58
    • 33748537441 scopus 로고    scopus 로고
    • Matrix metalloproteinase-3 expression profile differentiates adaptive and maladaptive synaptic plasticity induced by traumatic brain injury
    • Falo MC, Fillmore HL, Reeves TM, et al. Matrix metalloproteinase-3 expression profile differentiates adaptive and maladaptive synaptic plasticity induced by traumatic brain injury. J Neurosci Res 2006;84:768-81
    • (2006) J Neurosci Res , vol.84 , pp. 768-781
    • Falo, M.C.1    Fillmore, H.L.2    Reeves, T.M.3
  • 59
    • 40449131523 scopus 로고    scopus 로고
    • MRI identification of the rostral-caudal pattern of pathology within the corpus callosum in the cuprizone mouse model
    • Wu QZ, Yang Q, Cate HS, et al. MRI identification of the rostral-caudal pattern of pathology within the corpus callosum in the cuprizone mouse model. J Magn Reson Imaging 2008;27:446-53
    • (2008) J Magn Reson Imaging , vol.27 , pp. 446-453
    • Wu, Q.Z.1    Yang, Q.2    Cate, H.S.3
  • 60
    • 77954732542 scopus 로고    scopus 로고
    • Rostrocaudal analysis of corpus callosum demyelination and axon damage across disease stages refines diffusion tensor imaging correlations with pathological features
    • Xie M, Tobin JE, Budde MD, et al. Rostrocaudal analysis of corpus callosum demyelination and axon damage across disease stages refines diffusion tensor imaging correlations with pathological features. J Neuropathol Exp Neurol 2010;69:704-16
    • (2010) J Neuropathol Exp Neurol , vol.69 , pp. 704-716
    • Xie, M.1    Tobin, J.E.2    Budde, M.D.3
  • 61
    • 0036169207 scopus 로고    scopus 로고
    • Temporal lobe morphology in normal aging and traumatic brain injury
    • Bigler ED, Anderson CV, Blatter DD. Temporal lobe morphology in normal aging and traumatic brain injury. AJNR Am J Neuroradiol 2002;23:255-66
    • (2002) AJNR Am J Neuroradiol , vol.23 , pp. 255-266
    • Bigler, E.D.1    Anderson, C.V.2    Blatter, D.D.3
  • 62
    • 33947584670 scopus 로고    scopus 로고
    • Cerebellar atrophy after moderate-to-severe pediatric traumatic brain injury
    • Spanos GK, Wilde EA, Bigler ED, et al. Cerebellar atrophy after moderate-to-severe pediatric traumatic brain injury. AJNR Am J Neuroradiol 2007;28:537-42
    • (2007) AJNR Am J Neuroradiol , vol.28 , pp. 537-542
    • Spanos, G.K.1    Wilde, E.A.2    Bigler, E.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.