Long-term course of brain-derived neurotrophic factor serum levels in a patient treated with deep brain stimulation of the lateral habenula

Neuropsychobiology

Volumn 65, Issue 3, 2012, Pages 147-152

  Hoyer, Carolin ^a   Kranaster, Laura ^a   Sartorius, Alexander ^a   Hellweg, Rainer ^b   Gass, Peter ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Brain derived neurotrophic factor; Deep brain stimulation; Depression; Habenula

Indexed keywords

ANTIDEPRESSANT AGENT; BRAIN DERIVED NEUROTROPHIC FACTOR; LITHIUM; MIRTAZAPINE; RISPERIDONE; SERTRALINE; VENLAFAXINE;

ADULT; ARTICLE; BLOOD LEVEL; BRAIN DEPTH STIMULATION; CASE REPORT; DEPRESSION; DISEASE COURSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ELECTROCONVULSIVE THERAPY; FEMALE; HABENULA; HAMILTON SCALE; HUMAN; MAJOR DEPRESSION; PRIORITY JOURNAL; SERUM; UNSPECIFIED SIDE EFFECT;

BRAIN-DERIVED NEUROTROPHIC FACTOR; DEEP BRAIN STIMULATION; DEPRESSIVE DISORDER, MAJOR; FEMALE; HABENULA; HUMANS; LONGITUDINAL STUDIES; MIDDLE AGED; PSYCHIATRIC STATUS RATING SCALES; STATISTICS AS TOPIC;

EID: 84857499238     PISSN: 0302282X     EISSN: 14230224     Source Type: Journal    
DOI: 10.1159/000335243     Document Type: Article

References (53)

1. D'Sa C, Duman RS: Antidepressants and neuroplasticity. Bipolar Disord 2002; 4: 183-194. (Pubitemid 34591244)
2. Lewin GR, Barde YA: Physiology of the neurotrophins. Annu Rev Neurosci 1996; 19: 289-317. (Pubitemid 26080831)
3. Duman RS, Heninger GR, Nestler EJ: A molecular and cellular theory of depression. Arch Gen Psychiatry 1997; 54: 597-606. (Pubitemid 27306570)
4. Altar CA: Neurotrophins and depression. Trends Pharmacol Sci 1999; 20: 59-61. (Pubitemid 29323957)
5. Pittenger C, Duman RS: Stress, depression, and neuroplasticity: A convergence of mechanisms. Neuropsychopharmacology 2008; 33: 88-109. (Pubitemid 350191319)
6. Matrisciano F, Bonaccorso S, Ricciardi A, Scaccianoce S, Panaccione I, Wang L, Ruberto A, Tatarelli R, Nicoletti F, Girardi P, Shelton RC: Changes in BDNF serum levels in patients with major depression disorder (MDD) after 6 months treatment with sertraline, escitalopram, or venlafaxine. J Psychiatr Res 2009; 43: 247-254.
7. Nibuya M, Morinobu S, Duman RS: Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments. J Neurosci 1995; 15: 7539-7547.
8. Piccinni A, Del Debbio A, Medda P, Bianchi C, Roncaglia I, Veltri A, Zanello S, Massimetti E, Origlia N, Domenici L, Marazziti D, Dell'Osso L: Plasma brain-derived neurotrophic factor in treatment-resistant depressed patients receiving electroconvulsive therapy. Eur Neuropsychopharmacol 2009; 19: 349-355.
9. Shirayama Y, Chen AC, Nakagawa S, Russell DS, Duman RS: Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 2002; 22: 3251-3261. (Pubitemid 35379212)
10. Hoshaw BA, Malberg JE, Lucki I: Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects. Brain Res 2005; 1037: 204-208. (Pubitemid 40362398)
11. Sirianni RW, Olausson P, Chiu AS, Taylor JR, Saltzman WM: The behavioral and biochemical effects of BDNF containing polymers implanted in the hippocampus of rats. Brain Res 2010; 1321: 40-50.
12. Gourley SL, Kiraly DD, Howell JL, Olausson P, Taylor JR: Acute hippocampal brain-derived neurotrophic factor restores motivational and forced swim performance after corticosterone. Biol Psychiatry 2008; 64: 884-890.
13. Adachi M, Barrot M, Autry AE, Theobald D, Monteggia LM: Selective loss of brain-derived neurotrophic factor in the dentate gyrus attenuates antidepressant efficacy. Biol Psychiatry 2008; 63: 642-649. (Pubitemid 351329281)
14. Mossner R, Mikova O, Koutsilieri E, Saoud M, Ehlis AC, Muller N, Fallgatter AJ, Riederer P: Consensus paper of the WFSBP Task Force on Biological Markers: Biological markers in depression. World J Biol Psychiatry 2007; 8: 141-174. (Pubitemid 47163382)
15. Taliaz D, Loya A, Gersner R, Haramati S, Chen A, Zangen A: Resilience to chronic stress is mediated by hippocampal brain-derived neurotrophic factor. J Neurosci 2011; 31: 4475-4483.
16. Fujimura H, Altar CA, Chen R, Nakamura T, Nakahashi T, Kambayashi J, Sun B, Tandon NN: Brain-derived neurotrophic factor is stored in human platelets and released by agonist stimulation. Thromb Haemost 2002; 87: 728-734. (Pubitemid 34302963)
17. Radka SF, Holst PA, Fritsche M, Altar CA: Presence of brain-derived neurotrophic factor in brain and human and rat but not mouse serum detected by a sensitive and specific immunoassay. Brain Res 1996; 709: 122-301.
18. Pan W, Banks WA, Fasold MB, Bluth J, Kastin AJ: Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 1998; 37: 1553-1561. (Pubitemid 28550429)
19. Poduslo JF, Curran GL: Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Brain Res Mol Brain Res 1996; 36: 280-286. (Pubitemid 26095587)
20. Sartorius A, Hellweg R, Litzke J, Vogt M, Dormann C, Vollmayr B, Danker-Hopfe H, Gass P: Correlations and discrepancies between serum and brain tissue levels of neurotrophins after electroconvulsive treatment in rats. Pharmacopsychiatry 2009; 42: 270-276.
21. Schlapfer TE, Bewernick BH: Deep brain stimulation for psychiatric disorders -state of the art. Adv Tech Stand Neurosurg 2009; 34: 37-57.
22. Kennedy SH, Giacobbe P, Rizvi SJ, Placenza FM, Nishikawa Y, Mayberg HS, Lozano AM: Deep brain stimulation for treatment-resistant depression: Follow-up after 3 to 6 years. Am J Psychiatry 2011; 168: 502-510.
23. Blomstedt P, Sjoberg RL, Hansson M, Bodlund O, Hariz MI: Deep brain stimulation in the treatment of depression. Acta Psychiatr Scand 2011; 123: 4-11.
24. Sartorius A, Henn FA: Deep brain stimulation of the lateral habenula in treatment resistant major depression. Med Hypotheses 2007; 69: 1305-1308. (Pubitemid 47633054)
25. Sartorius A, Kiening KL, Kirsch P, von Gall CC, Haberkorn U, Unterberg AW, Henn FA, Meyer-Lindenberg A: Remission of major depression under deep brain stimulation of the lateral habenula in a therapy-refractory patient. Biol Psychiatry 2010; 67:e9-e11.
26. Hikosaka O, Sesack SR, Lecourtier L, Shepard PD: Habenula: Crossroad between the basal ganglia and the limbic system. J Neurosci 2008; 28: 11825-11829.
27. Sartorius A, Meyer-Lindenberg A: Deep brain stimulation of the lateral habenula to treat depression. Front Neurosci 2009; 3: 272.
28. Ziegenhorn AA, Schulte-Herbruggen O, Danker-Hopfe H, Malbranc M, Hartung HD, Anders D, Lang UE, Steinhagen-Thiessen E, Schaub RT, Hellweg R: Serum neurotrophins -a study on the time course and influencing factors in a large old age sample. Neurobiol Aging 2007; 28: 1436-1445. (Pubitemid 47090171)
29. Hellweg R, Lohmann P, Huber R, Kuhl A, Riepe MW: Spatial navigation in complex and radial mazes in APP23 animals and neurotrophin signaling as a biological marker of early impairment. Learn Mem 2006; 13: 63-71. (Pubitemid 43204397)
30. Brunoni AR, Lopes M, Fregni F: A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: Implications for the role of neuroplasticity in depression. Int J Neuropsychopharmacol 2008; 11: 1169-1180.
31. Friedman A, Frankel M, Flaumenhaft Y, Merenlender A, Pinhasov A, Feder Y, Taler M, Gil-Ad I, Abeles M, Yadid G: Programmed acute electrical stimulation of ventral tegmental area alleviates depressive-like behavior. Neuropsychopharmacology 2009; 34: 1057-1066.
32. Bocchio-Chiavetto L, Zanardini R, Bortolomasi M, Abate M, Segala M, Giacopuzzi M, Riva MA, Marchina E, Pasqualetti P, Perez J, Gennarelli M: Electroconvulsive therapy (ECT) increases serum brain derived neurotrophic factor (BDNF) in drug resistant depressed patients. Eur Neuropsychopharmacol 2006; 16: 620-624. (Pubitemid 44781079)
33. Martinowich K, Lu B: Interaction between BDNF and serotonin: Role in mood disorders. Neuropsychopharmacology 2008; 33: 73-83. (Pubitemid 350191318)
34. Mayberg HS, Lozano AM, Voon V, McNeely HE, Seminowicz D, Hamani C, Schwalb JM, Kennedy SH: Deep brain stimulation for treatment-resistant depression. Neuron 2005; 45: 651-660. (Pubitemid 40320700)
35. Monteleone P, Serritella C, Martiadis V, Maj M: Decreased levels of serum brain-derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I and II disorders. Bipolar Disord 2008; 10: 95-100.
36. Fernandes BS, Gama CS, Maria CK, Yatham LN, Fries GR, Colpo G, de Lucena D, Kunz M, Gomes FA, Kapczinski F: Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: A systematic review and meta-regression analysis. J Psychiatr Res 2011; 45: 995-1004.
37. Lang UE, Hellweg R, Gallinat J: BDNF serum concentrations in healthy volunteers are associated with depression-related personality traits. Neuropsychopharmacology 2004; 29: 795-798. (Pubitemid 38402487)
38. Kauer-Sant'Anna M, Tramontina J, Andreazza AC, Cereser K, da Costa S, Santin A, Yatham LN, Kapczinski F: Traumatic life events in bipolar disorder: Impact on BDNF levels and psychopathology. Bipolar Disord 2007; 9(suppl 1):128-135. (Pubitemid 47399255)
39. Kapczinski F, Dias VV, Frey BN, Kauer-Sant'Anna M: Brain-derived neurotrophic factor in bipolar disorder: Beyond trait and state: Comment on 'Decreased levels of serum brain-derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I and II disorders'. Bipolar Disord 2009; 11: 221-222.
40. Molendijk ML, Bus BA, Spinhoven P, Penninx BW, Kenis G, Prickaerts J, Voshaar RO, Elzinga BM: Serum levels of brain-derived neurotrophic factor in major depressive disorder: State-trait issues, clinical features and pharmacological treatment. Mol Psychiatry 2011; 16: 1088-1095.
41. Karege F, Schwald M, Cisse M: Postnatal developmental profile of brain-derived neurotrophic factor in rat brain and platelets. Neurosci Lett 2002; 328: 261-264. (Pubitemid 34876661)
42. Lang UE, Hellweg R, Seifert F, Schubert F, Gallinat J: Correlation between serum brainderived neurotrophic factor level and an in vivo marker of cortical integrity. Biol Psychiatry 2007; 62: 530-535. (Pubitemid 47284037)
43. Pardridge WM, Wu D, Sakane T: Combined use of carboxyl-directed protein pegylation and vector-mediated blood-brain barrier drug delivery system optimizes brain uptake of brain-derived neurotrophic factor following intravenous administration. Pharm Res 1998; 15: 576-582. (Pubitemid 28214951)
44. Schulte-Herbruggen O, Nassenstein C, Lommatzsch M, Quarcoo D, Renz H, Braun A: Tumor necrosis factor-alpha and interleukin-6 regulate secretion of brain-derived neurotrophic factor in human monocytes. J Neuroimmunol 2005; 160: 204-209. (Pubitemid 40248610)
45. Kerschensteiner M, Gallmeier E, Behrens L, Leal VV, Misgeld T, Klinkert WE, Kolbeck R, Hoppe E, Oropeza-Wekerle RL, Bartke I, Stadelmann C, Lassmann H, Wekerle H, Hohlfeld R: Activated human T cells, B cells, and monocytes produce brain-derived neurotrophic factor in vitro and in inflammatory brain lesions: A neuroprotective role of inflammation? J Exp Med 1999; 189: 865-870. (Pubitemid 29189691)
46. Muller N, Myint AM, Schwarz MJ: Inflammatory biomarkers and depression. Neurotox Res 2011; 19: 308-318.
47. Nagahara AH, Tuszynski MH: Potential therapeutic uses of BDNF in neurological and psychiatric disorders. Nat Rev Drug Discov 2011; 10: 209-219.
48. Greenberg ME, Xu B, Lu B, Hempstead BL: New insights in the biology of BDNF synthesis and release: Implications in CNS function. J Neurosci 2009; 29: 12764-12767.
49. Karege F, Bondolfi G, Gervasoni N, Schwald M, Aubry JM, Bertschy G: Low brain-derived neurotrophic factor (BDNF) levels in serum of depressed patients probably result from lowered platelet BDNF release unrelated to platelet reactivity. Biol Psychiatry 2005; 57: 1068-1072. (Pubitemid 40613035)
50. Parakh K, Sakhuja A, Bhat U, Ziegelstein RC: Platelet function in patients with depression. South Med J 2008; 101: 612-617.
51. Lederbogen F, Baranyai R, Gilles M, Menart-Houtermans B, Tschoepe D, Deuschle M: Effect of mental and physical stress on platelet activation markers in depressed patients and healthy subjects: A pilot study. Psychiatry Res 2004; 127: 55-64. (Pubitemid 38916867)
52. Hansson AC, Cintra A, Belluardo N, Sommer W, Bhatnagar M, Bader M, Ganten D, Fuxe K: Gluco-and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat. Eur J Neurosci 2000; 12: 2918-2934.
53. Tadic A, Wagner S, Schlicht KF, Peetz D, Borysenko L, Dreimuller N, Hiemke C, Lieb K: The early non-increase of serum BDNF predicts failure of antidepressant treatment in patients with major depression: A pilot study. Prog Neuropsychopharmacol Biol Psychiatry 2011; 35: 415-420.