Senescent cells in growing tumors: Population dynamics and cancer stem cells

PLoS Computational Biology

Volumn 8, Issue 1, 2012, Pages

  la Porta, Caterina A M ^a   Zapperi, Stefano ^b,c   Sethna, James P ^d  

^a UNIVERSITY OF MILAN   (Italy)

^b CNR   (Italy)

^c ISI FOUNDATION   (Italy)

^d Cornell University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; DISEASES; HIERARCHICAL SYSTEMS; STEM CELLS; STOCHASTIC MODELS; STOCHASTIC SYSTEMS; TUMORS;

CANCER CELLS; CANCER MODELS; CANCER STEM CELLS; CELL-BE; CELL/B.E; CELL/BE; RANDOM MUTATION; STOCHASTICS; TUMOR GROWTH; TUMOR POPULATION;

CANCER CELLS;

SURVIVIN; ABC TRANSPORTER; ABCG2 PROTEIN, HUMAN; BIRC5 PROTEIN, HUMAN; INHIBITOR OF APOPTOSIS PROTEIN; TUMOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CANCER MODEL; CANCER STEM CELL; CELL AGING; CELL POPULATION; CELL SPECIFICITY; CONTROLLED STUDY; CYTOLOGY; HUMAN; HUMAN CELL; MATHEMATICAL MODEL; MELANOMA CELL; MOLECULAR EVOLUTION; MOUSE; NONHUMAN; PREDICTION; TARGET CELL; BIOLOGICAL MODEL; BIOLOGY; BIOSYNTHESIS; CELL GROWTH; CELL HYPOXIA; CLUSTER ANALYSIS; COMPUTER SIMULATION; GENETIC TRANSFECTION; GENETICS; MELANOMA; MESENCHYMAL STEM CELL; METABOLISM; PATHOLOGY; PHYSIOLOGY; STATISTICS; TUMOR CELL LINE; XENOGRAFT;

ATP-BINDING CASSETTE TRANSPORTERS; CELL AGING; CELL GROWTH PROCESSES; CELL HYPOXIA; CELL LINE, TUMOR; CLUSTER ANALYSIS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MELANOMA; MESENCHYMAL STEM CELLS; MODELS, BIOLOGICAL; NEOPLASM PROTEINS; NEOPLASTIC STEM CELLS; STOCHASTIC PROCESSES; TRANSFECTION; TRANSPLANTATION, HETEROLOGOUS;

EID: 84857461938     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002316     Document Type: Article

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