Role of symmetric and asymmetric division of stem cells in developing drug resistance

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 39, 2010, Pages 16766-16771

  Tomasetti, Cristian ^a   Levy, Doron ^a  

^a Bldg 142   (United States)

Author keywords

Branching processes; Cancer stem cells; Symmetric renewal

Indexed keywords

IMATINIB; ANTINEOPLASTIC AGENT; BENZAMIDE DERIVATIVE; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ARTICLE; CANCER MODEL; CANCER STEM CELL; CELL DIFFERENTIATION; CELL DIVISION; CELL POPULATION; CELL RENEWAL; CHRONIC MYELOID LEUKEMIA; DRUG RESISTANCE; GENE MUTATION; HUMAN; MATHEMATICAL MODEL; POINT MUTATION; PRIORITY JOURNAL; BIOLOGICAL MODEL; DRUG EFFECTS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; PATHOLOGY; PHYSIOLOGY;

ANTINEOPLASTIC AGENTS; BENZAMIDES; CELL DIVISION; DRUG RESISTANCE, NEOPLASM; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MODELS, BIOLOGICAL; NEOPLASTIC STEM CELLS; PIPERAZINES; PYRIMIDINES;

EID: 78049262473     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1007726107     Document Type: Article

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