Ligand-induced movements of inner transmembrane helices of Glut1 revealed by chemical cross-linking of di-cysteine mutants

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Mueckler, Mike ^a   Makepeace, Carol ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTINE; CYTOCHALASIN B; ETHYLIDENE GLUCOSE; GLUCOSE DERIVATIVE; GLUCOSE TRANSPORTER 1; LIGAND; UNCLASSIFIED DRUG; CROSS LINKING REAGENT; CYSTEINE; DEOXYGLUCOSE; MUTANT PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CONTROLLED STUDY; CROSS LINKING; CYTOPLASM; GLUCOSE METABOLISM; IMMUNOBLOTTING; INTRACELLULAR MEMBRANE; NONHUMAN; OOCYTE; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RESIDUE ANALYSIS; SENSITIVITY ANALYSIS; ANIMAL; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MOVEMENT (PHYSIOLOGY); MUTATION; NUCLEOTIDE SEQUENCE; PROTEIN SECONDARY STRUCTURE; REPORTER GENE; STRUCTURAL HOMOLOGY; STRUCTURE ACTIVITY RELATION; XENOPUS;

ANIMALS; BASE SEQUENCE; CELL MEMBRANE; CROSS-LINKING REAGENTS; CYSTEINE; DEOXYGLUCOSE; GENES, REPORTER; GLUCOSE TRANSPORTER TYPE 1; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOVEMENT; MUTANT PROTEINS; MUTATION; OOCYTES; PROTEIN STRUCTURE, SECONDARY; STRUCTURAL HOMOLOGY, PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP; XENOPUS;

EID: 84857412279     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031412     Document Type: Article

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