Influence of a functional polymorphism within the promoter of the serotonin transporter gene on the effects of total sleep deprivation in bipolar depression

American Journal of Psychiatry

Volumn 156, Issue 9, 1999, Pages 1450-1452

  Benedetti, Francesco ^a   Serretti, Alessandro ^b   Colombo, Cristina ^b   Campori, Euridice ^b   Barbini, Barbara ^b   Di Bella, Daniela ^b   Smeraldi, Enrico ^b  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIDEPRESSANT AGENT; FLUVOXAMINE; PAROXETINE; PINDOLOL; SEROTONIN; SEROTONIN 1A ANTAGONIST;

ADULT; ARTICLE; BIPOLAR DEPRESSION; CLINICAL TRIAL; DEPRESSION; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HAMILTON SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOOD; NEUROTRANSMISSION; PRIORITY JOURNAL; PROMOTER REGION; SEROTONINERGIC SYSTEM; SLEEP DEPRIVATION; TREATMENT OUTCOME;

ADULT; ANALYSIS OF VARIANCE; BIPOLAR DISORDER; CARRIER PROTEINS; FEMALE; GENES, REGULATOR; HETEROZYGOTE; HOMOZYGOTE; HOSPITALIZATION; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; MIDDLE AGED; NERVE TISSUE PROTEINS; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SLEEP DEPRIVATION;

EID: 0032832348     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Gardner JP, Fornal CA, Jacobs BL: Effects of sleep deprivation on serotonergic neuronal activity in the dorsal raphe nucleus of the freely moving cat. Neuropsychopharmacology 1997; 17:72-81
2. Smeraldi E, Benedetti F, Barbini B, Campori C, Colombo C: Sustained antidepressant effect of sleep deprivation combined with pindolol in bipolar depression: a placebo-controlled trial. Neuropsychopharmacology 1999; 20:380-385
3. Lesch KP, Bengel D, Heils A, Sabol S, Greenberg BD, Petri S, Benjamin J, Müller CR, Hamer DH, Murphy DL: Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996; 274:1527-1531
4. Little KY, McLaughlin DP, Zhang L, Livermore CS, Dalack GW, McFinton PR, DelProposto ZS, Hill E, Cassin BJ, Watson SJ, Cook EH: Cocaine, ethanol, and genotype effects on human midbrain serotonin transporter binding sites and mRNA levels. Am J Psychiatry 1998; 155:207-213
5. Hanna GL, Himle JA, Curtis GC, Koram DQ, Weele JV, Leventhal BL, Cook EH Jr: Serotonin transporter and seasonal variation in blood serotonin in families with obsessive-compulsive disorder. Neuropsychopharmacology 1998; 18:102-111
6. Smeraldi E, Zanardi R, Benedetti F, Di Bella D, Perez J, Catalano M: Polymorphism within the promoter of the serotonin transporter gene and antidepressant efficacy of fluvoxamine. Mol Psychiatry 1998; 3:508-511
7. Zanardi R, Benedetti F, Di Bella D, Catalano M, Smeraldi E: Efficacy of paroxetine in depression is influenced by a functional polymorphism within the promoter of the serotonin transporter gene. J Clin Psychopharmacol (in press)
8. Hamilton M: A rating scale for depression. J Neurol Neurosurg Psychiatry 1960; 23:56-62
9. Deckert J, Catalano M, Heils A, Di Bella D, Friess F, Politi E, Franke P, Nöthen MM, Maier W, Bellodi L, Lesch KP: Functional promoter polymorphism of the human serotonin transporter: lack of association with panic disorder. Psychiatr Genet 1997; 7:45-47
10. Comings D: Polygenic inheritance in psychiatric disorders, in Handbook of Psychiatric Genetics. Edited by Blum K, Noble EP, Boca Raton, Fla, CRC Press, 1997, pp 235-260
11. Ebert D, Berger M: Neurobiological similarities in antidepressant sleep deprivation and psychostimulant use: a psycho-stimulant theory of antidepressant sleep deprivation. Psychopharmacology (Berl) 1998; 140:1-10