Recombinant human erythropoietin prevents cisplatin-induced genotoxicity in rat liver and heart tissues via an antioxidant process

Drug and Chemical Toxicology

Volumn 35, Issue 2, 2012, Pages 134-140

  Rjiba Touati, Karima ^a   Ayed Boussema, Imen ^a   Belarbia, Anis ^b   Achour, Abdelatif ^b   Bacha, Hassen ^a  

^a Faculty of Dentistry   (Tunisia)

^b University Hospital of Sahloul   (Tunisia)

Author keywords

Antigenotoxic effect; Antioxidant property; Cisplatin; Heart; Liver; RhEPO

Indexed keywords

CARBONYL DERIVATIVE; CATALASE; CISPLATIN; GLUTATHIONE; RECOMBINANT ERYTHROPOIETIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CARDIOTOXICITY; CELL PROTECTION; COMET ASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; GENOTOXICITY; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; SINGLE DRUG DOSE;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; CATALASE; CISPLATIN; COMET ASSAY; DNA DAMAGE; ERYTHROPOIETIN; GLUTATHIONE; HEART; LIVER; MALE; MYOCARDIUM; OXIDATIVE STRESS; PROTEIN CARBONYLATION; RANDOM ALLOCATION; RATS; RATS, WISTAR; RECOMBINANT PROTEINS;

EID: 84857322335     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.3109/01480545.2011.589445     Document Type: Article

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