Free radical generation induces epithelial-to-mesenchymal transition in lung epithelium via a TGF-β1-dependent mechanism

Free Radical Biology and Medicine

Volumn 52, Issue 6, 2012, Pages 1024-1032

  Gorowiec, Marta R ^a   Borthwick, Lee A ^a   Parker, Sean M ^a   Kirby, John A ^a   Saretzki, Gabriele C ^a   Fisher, Andrew J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

EMT; oxidative stress; TGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; EXTRACELLULAR SUPEROXIDE DISMUTASE; FREE RADICAL; HYDROGEN PEROXIDE; N TERT BUTYL ALPHA PHENYLNITRONE; PROTEIN ZO1; TRANSFORMING GROWTH FACTOR BETA1; UVOMORULIN; VIMENTIN;

ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

AIRWAY REMODELING; ANTIOXIDANTS; BIOLOGICAL MARKERS; CELL LINE; ENZYME INHIBITORS; EPITHELIAL-MESENCHYMAL TRANSITION; FREE RADICALS; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; IDIOPATHIC PULMONARY FIBROSIS; LUNG; OXIDATIVE STRESS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY MUCOSA; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84857232618     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.12.020     Document Type: Article

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