Biochemical label-free tissue imaging with subcellular-resolution synchrotron FTIR with focal plane array detector

NeuroImage

Volumn 60, Issue 1, 2012, Pages 376-383

  Kastyak Ibrahim, M Z ^a   Nasse, M J ^b,c   Rak, M ^b   Hirschmugl, C ^b   Del Bigio, M R ^a   Albensi, B C ^d   Gough, K M ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

^b UNIVERSITY OF WISCONSIN MILWAUKEE   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Alzheimer; Brain; FTIR imaging; IRENI; Neuron; Retina

Indexed keywords

SATURATED FATTY ACID; UNSATURATED FATTY ACID;

ACCURACY; ALZHEIMER DISEASE; AMYLOID PLAQUE; ANALYTICAL EQUIPMENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOCHEMICAL COMPOSITION; BRAIN NERVE CELL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FATTY ACID ANALYSIS; HIPPOCAMPAL CA1 REGION; INFRARED ENVIRONMENTAL IMAGING; INFRARED SPECTROSCOPY; MOLECULAR IMAGING; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERIKARYON; PREDICTION; PRIORITY JOURNAL; RETINA NERVE CELL; SENSITIVITY AND SPECIFICITY; SIGNAL NOISE RATIO; SYNAPTIC MEMBRANE; SYNCHROTRON; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; ANIMALS; BIOCHEMICAL PROCESSES; MICE; MICE, INBRED C57BL; NEURONS; RETINA; SPECTROSCOPY, FOURIER TRANSFORM INFRARED;

EID: 84857136573     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2011.11.069     Document Type: Article

References (39)

1. Bassan P., Kohler A., Martens H., Lee J., Byrne H.J., Dumas P., Gazi E., Brown M., Clarke N., Gardner P. Resonant Mie Scattering (RMieS) correction of infrared spectra from highly scattering biological samples. Analyst 2010, 135:268-277.
2. Carr G.L. Resolution limits for infrared microspectroscopy explored with synchrotron radiation. Rev. Sci. Instrum. 2001, 72:1613-1619.
3. Carter-Dawson L.D., Lavail M.M. Rods and cones in the mouse retina. I. Structural analysis using light and electron microscopy. J. Comp. Neur. 1979, 188:245-262.
4. Chalmers J.M., Griffiths P.R. Handbook of Vibrational Spectroscopy 2002, vol. 1-5. Wiley, Chichester UK.
5. Chishti M.A., Yang D., Janus C., Phinney A.L., Horne P., Pearson J., Strome R., Zuker N., Loukides J., French J., Turner S., Lozza G., Grilli M., Kunicki S., Morissette C., Paquette J., Gervais F., Bergeron C., Fraser P.E.M., Carlson G.A., St.George-Hyslop P., Westaway D. Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695. J. Biol. Chem. 2001, 276:21562-21570.
6. Connor K., SanGiovanni J., Lofgvist C., Aderman C.M., Chen J., Higuchi A., Hong S., Pravda E.A., Majchrzak S., Carper D., Hellstrom A., Kang J.X., Chew E.Y., Salem N., Serhan C.N., Smith L.E.H. Increased dietary intake of ω-3-polyunsaturated fatty acids reduced pathological retinal angiogenesis. Nat. Med. 2007, 13:868-873.
7. Cuthbertson R.A., Mandel T.E. Anatomy of the mouse retina. Endothelial cell-pericyte ratio and capillary distribution. Invest Ophthalmol. Visual Sci. 1986, 27:1659-1664.
8. Dumas P., Sockalingum G.D., Sule-Suso J. Adding synchrotron radiation to infrared microspectroscopy: what's new in biomedical applications?. Trends Biotechnol. 2007, 25:40-44.
9. Fliesler S.J., Anderson R.E. Chemistry and metabolism of lipids in the vertebrate retina. Prog. Lipids Res. 1983, 22:79-131.
10. Florent-Bechard S., Desbene C., Garcia P., Allouche A., Youssef I., Escanye M.C., Koziel V., Hanse M., Malaplate-Armand C., Stenger C., Kriem B., Yen-Potin F.T., Olivier J.L., Pillot T., Oster T. The essential role of lipids in Alzheimer's disease. Biochimie 2009, 91:804-809.
11. Gambis A., Dourlen P., Steller H., Bertrand Mollereau Two-color in vivo imaging of photoreceptor apoptosis and development in Drosophila. Develop. Biol. 2011, 351:128-134.
12. Guo L., Duggan J., Cordeiro M.F. Alzheimer's disease and retinal neurodegeneration. Curr. Alzheimer Res. 2010, 7:3-14.
13. Hartmann J., Kiewert C., Duysen E.G., Lockridge O., Greig N.H., Klein J. Excessive hippocampal acetylcholine levels in acetylcholinesterase-deficient mice are moderated by butyrylcholinesterase activity. J. Neurochem. 2007, 100:1421-1429.
14. Huffman S.W., Bhargava R., Levin I.W. Generalized implementation of rapid-scan Fourier transform infrared spectroscopic imaging. Appl. Spectrosc. 2002, 56:965-969.
15. Jeffrey B.G., Weisinger H.S., Neuringer M., Mitchell D.C. The Role of Docosahexaenoic Acid in Retinal Function. Lipids 2001, 36:859-870.
16. Jensen T.H., Bech M., Bunk O., Menzel A., Bouchet A., Le Duc G., Feidenhans'l R., Pfeiffer F. Molecular X-ray computed tomography of myelin in a rat brain. Neuroimage 2011, 57:124-129.
17. Kastyak M.Z., Szczerbowska-Boruchowska M., Adamek D., Tomik B., Lankosz M., Gough K.M. Pigmented creatine deposits in Amyotrophic Lateral Sclerosis central nervous system tissues identified by Synchrotron FTIR microspectroscopy and X-ray fluorescence spectromicroscopy. Neuroscience 2010, 166:1119-1128.
18. Kokotas H., Grigoriadou M., Petersen M.B. Age-related macular degeneration: genetic and clinical findings. Clin. Chem. Lab. Med: CCLM/FESCC 2011, 49:601-616.
19. Kuzyk A., Kastyak M.Z., Agrawal V., Gallant M., Sivakumar G., Rak M., Del Bigio M.R., Westaway D., Julian R., Gough K.M. Association among amyloid plaque, lipid, and creatine in hippocampus of TgCRND8 mouse model for Alzheimer disease. J. Biol. Chem. 2010, 285:31202-31207.
20. Levine S.M., Radel J.D., Sweat J.A., Wetzel D.L. Microchemical analysis of retina layers in pigmented and albino rats by Fourier transform infrared microspectroscopy. Biochem. Biophys. Acta 1999, 1473:409-417.
21. Lucas S., Rothwell N.J., Gibson R.M. The role of inflammation in CNS injury and disease. Br. J. Pharmacol. 2006, 147(S1):S232-S240.
22. Martins I.C., Kuperstein I., Wilkinson H., Maes E., Vanbrabant M., Jonckheere W., Van Gelder P., Hartmann D., D'Hooge R., De Strooper B., Schymkowitz J., Rousseau F. Lipids revert inert Aβ amyloid fibrils to neurotoxic protofibrils that affect learning in mice. EMBO J. 2008, 27:224-233.
23. Mattson M.P. Pathways towards and away from Alzheimer's disease. Nature 2004, 430:631-639.
24. Miller L.R., Smith R.J. Synchrotrons versus Globars, point-detectors versus focal plane arrays: selecting the best source and detector for specific infrared microspectroscopy and imaging applications. Vib. Spectrosc. 2005, 38:237-240.
25. Nasse M.J., Walsh M.J., Mattson E.C., Reininger R., Kajdacsy-Balla A., Macias V., Bhargava R., Hirschmugl C.J. High-resolution Fourier-transform infrared chemical imaging with multiple synchrotron beams. Nature Meth. 2011, 8:413-416.
26. Nasse M.J., Reininger R., Kubala T., Janowski S., Hirschmugl C. Synchrotron infrared microspectroscopy imaging using a multi-element detector (IRMSI-MED) for diffraction-limited chemical imaging. Nucl. Instrum. Methods Phys. Res., Sect. A 2007, 582:107-110.
27. Oddo S., Caccamo A., Shepherd J.D., et al. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction. Neuron 2003, 39:409-421.
28. Rak M., Del Bigio M.R., Mai S., Westaway D., Gough K.M. Dense-core and diffuse Abeta plaques in TgCRND8 mice studied with synchrotron FTIR microspectroscopy. Biopolymers 2007, 87:207-211.
29. Schjeide B.M., McQueen M.B., Mullin K., Divito J., Hogan M.F., Parkinson M., Hooli B., Lange C., Blacker D., Tanzi R.E., Bertram L. Assessment of Alzheimer's disease case-control associations using family-based methods. Neurogenetics 2009, 10:19-25.
30. Schnebelen C., Gregoire S., Pasquis B., Joffre C., Creuzot-Garcher C.P., Bron A.M., Bretillon L., Acar N. Dietary n-3 and n-6 PUFA enhance DHA incorporation in retinal phospholipids without affecting PGE1 and PGE2 levels. Lipids 2009, 44:465-470.
31. Schulz G., Weitkamp T., Zanette I., Pfeiffer F., Beckmann F., David C., Rutishauser S., Reznikova E., Müller B. High-resolution tomographic imaging of a human cerebellum: comparison of absorption and grating-based phase contrast. J. R. Soc. Interface 2010, 7:1665-1676.
32. Selkoe D.J. Cell biology of protein misfolding: the examples of Alzheimer's and Parkinson's diseases. Nature Cell Biol. 2004, 6:1054-1061.
33. Seshadri S., Khurana R., Fink A.L. Fourier transform infrared spectroscopy in analysis of protein deposits. Methods Enzymol. 1999, 309:559-576.
34. Simopoulos A.P., Bazan N.G. Omega-3 fatty acids, the brain and retina. World Rev. Nutr. Diet. 2009, vol. 99.
35. Suh M., Wierzbicki A.A., Clandinin M.T. Dietary n-3 FA modulate long and very long chain FA content, rhodopsin content and rhodopsin phosphorylation in rat rod outer segment after light exposure. Lipids 2002, 37:253-260.
36. Wiens R., Rak M., Cox N., Abraham S., Juurlink B.H.J., Kulyk W.M., Gough K.M. Synchrotron FTIR microspectroscopic analysis of the effects of anti-inflammatory therapeutics on wound healing in laminectomized rats. Anal. Bioanal. Chem. 2007, 387:1679-1689.
37. Winton M.J., Lee E.B., Sun E., Wong M.M., Leight S., Zhang B., Trojanowski J.Q., Lee V.M.-Y. Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration. J. Neurosci. 2011, 31:7691-7699.
38. Witte S., Negrean A., Lodder J.C., de Kock C.P.J., Silva G.T., Mansvelder H.D., Groot M.L. Label-free live brain imaging and targeted patching with third-harmonic generation microscopy. PNAS Mar. 2011, 28:1-6.
39. MATLAB® (2009, The MathWorks, Natick, MA); Felix Totir and Ian Howat (2010) ENVI file reader/writer, available from: http://www.mathworks.com/matlabcentral/fileexchange/27172.