Recognition of anesthetic barbiturates by a protein binding site: A high resolution structural analysis

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Oakley, Simon ^a   Vedula, L Sangeetha ^a   Bu, Weiming ^a   Meng, Qing Cheng ^a   Xi, Jin ^a   Liu, Renyu ^a   Eckenhoff, Roderic G ^a   Loll, Patrick J ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOFERRITIN; BARBITURIC ACID DERIVATIVE; PENTOBARBITAL; PHENOBARBITAL; PROPOFOL; THIOPENTAL; ANESTHETIC AGENT;

ARTICLE; BINDING AFFINITY; BINDING SITE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG DETERMINATION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG STRUCTURE; GABAERGIC SYSTEM; HYDROPHOBICITY; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; STRUCTURE ANALYSIS; X RAY ANALYSIS; ANIMAL; CHEMISTRY; HORSE; METABOLISM; PROTEIN BINDING; X RAY CRYSTALLOGRAPHY;

ANESTHETICS; ANIMALS; APOFERRITINS; BARBITURATES; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HORSES; PENTOBARBITAL; PROTEIN BINDING; THIOPENTAL;

EID: 84857136424     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0032070     Document Type: Article

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