Partial correction of defective Cl- secretion in cystic fibrosis epithelial cells by an analog of squalamine

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 281, Issue 5 25-5, 2001, Pages

  Jiang, Canwen ^a   Lee, Edward R ^a   Lane, Mathieu B ^a   Xiao, Yong Fu ^b   Harris, David J ^a   Cheng, Seng H ^a  

^a GENZYME CORPORATION   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Chloride ion; Cystic fibrosis transmembrane conductance regulator; Nasal potential difference; Ussing chamber; Whole cell patch clamp

Indexed keywords

ANION CHANNEL; CYCLIC AMP; SQUALAMINE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; APICAL MEMBRANE; ARTICLE; CELL MEMBRANE PERMEABILITY; CHLORIDE TRANSPORT; CONTROLLED STUDY; CYSTIC FIBROSIS; HYPERPOLARIZATION; LUNG ALVEOLUS EPITHELIUM; LUNG PERFUSION; MEMBRANE CURRENT; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; TRANSGENIC MOUSE;

EID: 0035194937     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2001.281.5.l1164     Document Type: Article

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