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Volumn 196, Issue , 2012, Pages 49-61

Genetically encoded molecular tools for light-driven silencing of targeted neurons

Author keywords

Archaerhodopsin; Causality; Cell types; Channelrhodopsin; Control; Halorhodopsin; Neural circuits; Neural silencing; Opsins; Optogenetics

Indexed keywords

BACTERIORHODOPSIN; HALORHODOPSIN; OPSIN; PROTON PUMP;

EID: 84857097106     PISSN: 00796123     EISSN: 18757855     Source Type: Book Series    
DOI: 10.1016/B978-0-444-59426-6.00003-3     Document Type: Chapter
Times cited : (43)

References (91)
  • 1
    • 36248996490 scopus 로고    scopus 로고
    • Neural substrates of awakening probed with optogenetic control of hypocretin neurons
    • Adamantidis A.R., Zhang F., Aravanis A.M., Deisseroth K., de Lecea L. Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature 2007, 450(7168):420-424.
    • (2007) Nature , vol.450 , Issue.7168 , pp. 420-424
    • Adamantidis, A.R.1    Zhang, F.2    Aravanis, A.M.3    Deisseroth, K.4    de Lecea, L.5
  • 3
    • 34547133175 scopus 로고    scopus 로고
    • An optical neural interface: In vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology
    • Aravanis A.M., Wang L.P., Zhang F., Meltzer L.A., Mogri M.Z., Schneider M.B., et al. An optical neural interface: In vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology. Journal of Neural Engineering 2007, 4(3):S143-S156.
    • (2007) Journal of Neural Engineering , vol.4 , Issue.3
    • Aravanis, A.M.1    Wang, L.P.2    Zhang, F.3    Meltzer, L.A.4    Mogri, M.Z.5    Schneider, M.B.6
  • 4
    • 49049099862 scopus 로고    scopus 로고
    • A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping
    • Atasoy D., Aponte Y., Su H.H., Sternson S.M. A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping. Journal of Neuroscience 2008, 28(28):7025-7030.
    • (2008) Journal of Neuroscience , vol.28 , Issue.28 , pp. 7025-7030
    • Atasoy, D.1    Aponte, Y.2    Su, H.H.3    Sternson, S.M.4
  • 5
    • 25444463058 scopus 로고    scopus 로고
    • Xanthorhodopsin: A proton pump with a light-harvesting carotenoid antenna
    • Balashov S.P., Imasheva E.S., Boichenko V.A., Anton J., Wang J.M., Lanyi J.K. Xanthorhodopsin: A proton pump with a light-harvesting carotenoid antenna. Science 2005, 309(5743):2061-2064.
    • (2005) Science , vol.309 , Issue.5743 , pp. 2061-2064
    • Balashov, S.P.1    Imasheva, E.S.2    Boichenko, V.A.3    Anton, J.4    Wang, J.M.5    Lanyi, J.K.6
  • 7
    • 0034665853 scopus 로고    scopus 로고
    • Bacterial rhodopsin: Evidence for a new type of phototrophy in the sea
    • Beja O., Aravind L., Koonin E.V., Suzuki M.T., Hadd A., Nguyen L.P., et al. Bacterial rhodopsin: Evidence for a new type of phototrophy in the sea. Science 2000, 289(5486):1902-1906.
    • (2000) Science , vol.289 , Issue.5486 , pp. 1902-1906
    • Beja, O.1    Aravind, L.2    Koonin, E.V.3    Suzuki, M.T.4    Hadd, A.5    Nguyen, L.P.6
  • 9
    • 57349151754 scopus 로고    scopus 로고
    • Channelrhodopsin-1 initiates phototaxis and photophobic responses in chlamydomonas by immediate light-induced depolarization
    • Berthold P., Tsunoda S.P., Ernst O.P., Mages W., Gradmann D., Hegemann P. Channelrhodopsin-1 initiates phototaxis and photophobic responses in chlamydomonas by immediate light-induced depolarization. The Plant Cell 2008, 20(6):1665-1677.
    • (2008) The Plant Cell , vol.20 , Issue.6 , pp. 1665-1677
    • Berthold, P.1    Tsunoda, S.P.2    Ernst, O.P.3    Mages, W.4    Gradmann, D.5    Hegemann, P.6
  • 10
    • 33645974269 scopus 로고    scopus 로고
    • Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration
    • Bi A., Cui J., Ma Y.P., Olshevskaya E., Pu M., Dizhoor A.M., et al. Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration. Neuron 2006, 50(1):23-33.
    • (2006) Neuron , vol.50 , Issue.1 , pp. 23-33
    • Bi, A.1    Cui, J.2    Ma, Y.P.3    Olshevskaya, E.4    Pu, M.5    Dizhoor, A.M.6
  • 11
    • 0000830257 scopus 로고
    • The halo-opsin gene. II. Sequence, primary structure of halorhodopsin and comparison with bacteriorhodopsin
    • Blanck A., Oesterhelt D. The halo-opsin gene. II. Sequence, primary structure of halorhodopsin and comparison with bacteriorhodopsin. EMBO Journal 1987, 6(1):265-273.
    • (1987) EMBO Journal , vol.6 , Issue.1 , pp. 265-273
    • Blanck, A.1    Oesterhelt, D.2
  • 12
    • 79955684899 scopus 로고    scopus 로고
    • A history of optogenetics: The development of tools for controlling brain circuits with light
    • Boyden E.S. A history of optogenetics: The development of tools for controlling brain circuits with light. F1000 Biology Reports 2011, 3:11.
    • (2011) F1000 Biology Reports , vol.3 , pp. 11
    • Boyden, E.S.1
  • 13
    • 26444621497 scopus 로고    scopus 로고
    • Millisecond-timescale, genetically targeted optical control of neural activity
    • Boyden E.S., Zhang F., Bamberg E., Nagel G., Deisseroth K. Millisecond-timescale, genetically targeted optical control of neural activity. Nature Neuroscience 2005, 8(9):1263-1268.
    • (2005) Nature Neuroscience , vol.8 , Issue.9 , pp. 1263-1268
    • Boyden, E.S.1    Zhang, F.2    Bamberg, E.3    Nagel, G.4    Deisseroth, K.5
  • 14
    • 0023645168 scopus 로고
    • Structure-function studies on bacteriorhodopsin. IV. Purification and renaturation of bacterio-opsin polypeptide expressed in Escherichia coli
    • Braiman M.S., Stern L.J., Chao B.H., Khorana H.G. Structure-function studies on bacteriorhodopsin. IV. Purification and renaturation of bacterio-opsin polypeptide expressed in Escherichia coli. Journal of Biological Chemistry 1987, 262(19):9271-9276.
    • (1987) Journal of Biological Chemistry , vol.262 , Issue.19 , pp. 9271-9276
    • Braiman, M.S.1    Stern, L.J.2    Chao, B.H.3    Khorana, H.G.4
  • 15
    • 3242797479 scopus 로고    scopus 로고
    • Fungal rhodopsins and opsin-related proteins: Eukaryotic homologues of bacteriorhodopsin with unknown functions
    • Brown L.S. Fungal rhodopsins and opsin-related proteins: Eukaryotic homologues of bacteriorhodopsin with unknown functions. Photochemical and Photobiological Sciences 2004, 3(6):555-565.
    • (2004) Photochemical and Photobiological Sciences , vol.3 , Issue.6 , pp. 555-565
    • Brown, L.S.1
  • 16
    • 0030482036 scopus 로고    scopus 로고
    • Interaction of proton and chloride transfer pathways in recombinant bacteriorhodopsin with chloride transport activity: Implications for the chloride translocation mechanism
    • Brown L.S., Needleman R., Lanyi J.K. Interaction of proton and chloride transfer pathways in recombinant bacteriorhodopsin with chloride transport activity: Implications for the chloride translocation mechanism. Biochemistry 1996, 35(50):16048-16054.
    • (1996) Biochemistry , vol.35 , Issue.50 , pp. 16048-16054
    • Brown, L.S.1    Needleman, R.2    Lanyi, J.K.3
  • 17
    • 39849100668 scopus 로고    scopus 로고
    • Fiber-coupled light-emitting diode for localized photostimulation of neurons expressing channelrhodopsin-2
    • Campagnola L., Wang H., Zylka M.J. Fiber-coupled light-emitting diode for localized photostimulation of neurons expressing channelrhodopsin-2. Journal of Neuroscience Methods 2008, 169(1):27-33.
    • (2008) Journal of Neuroscience Methods , vol.169 , Issue.1 , pp. 27-33
    • Campagnola, L.1    Wang, H.2    Zylka, M.J.3
  • 18
    • 80055103882 scopus 로고    scopus 로고
    • Scalable fluidic injector arrays for viral targeting of intact 3-D brain circuits
    • 35. pii: 1489. doi: 10.3791/1489
    • Chan S.C., Bernstein J., Boyden E. Scalable fluidic injector arrays for viral targeting of intact 3-D brain circuits. Journal of Visualized Experiments 2009, 35. pii: 1489. doi: 10.3791/1489.
    • (2009) Journal of Visualized Experiments
    • Chan, S.C.1    Bernstein, J.2    Boyden, E.3
  • 19
    • 33947429297 scopus 로고    scopus 로고
    • Identification of cell-type-specific promoters within the brain using lentiviral vectors
    • Chhatwal J.P., Hammack S.E., Jasnow A.M., Rainnie D.G., Ressler K.J. Identification of cell-type-specific promoters within the brain using lentiviral vectors. Gene Therapy 2007, 14(7):575-583.
    • (2007) Gene Therapy , vol.14 , Issue.7 , pp. 575-583
    • Chhatwal, J.P.1    Hammack, S.E.2    Jasnow, A.M.3    Rainnie, D.G.4    Ressler, K.J.5
  • 20
    • 79957480743 scopus 로고    scopus 로고
    • Synthetic physiology strategies for adapting tools from nature for genetically targeted control of fast biological processes
    • Chow B.Y., Chuong A.S., Klapoetke N.C., Boyden E.S. Synthetic physiology strategies for adapting tools from nature for genetically targeted control of fast biological processes. Methods in Enzymology 2011, 497:425-443.
    • (2011) Methods in Enzymology , vol.497 , pp. 425-443
    • Chow, B.Y.1    Chuong, A.S.2    Klapoetke, N.C.3    Boyden, E.S.4
  • 21
    • 79952368251 scopus 로고    scopus 로고
    • Light-activated ion pumps and channels for temporally precise optical control of activity in genetically targeted neurons
    • Humana Press, New York, J.J. Chambers, R.H. Kramer (Eds.)
    • Chow B.Y., Han X., Bernstein J.G., Monahan P.E., Boyden E.S. Light-activated ion pumps and channels for temporally precise optical control of activity in genetically targeted neurons. Photosensitive molecules for controlling biological function 2011, 99-132. Humana Press, New York. J.J. Chambers, R.H. Kramer (Eds.).
    • (2011) Photosensitive molecules for controlling biological function , pp. 99-132
    • Chow, B.Y.1    Han, X.2    Bernstein, J.G.3    Monahan, P.E.4    Boyden, E.S.5
  • 22
    • 73849143150 scopus 로고    scopus 로고
    • High-performance genetically targetable optical neural silencing by light-driven proton pumps
    • Chow B.Y., Han X., Dobry A.S., Qian X., Chuong A.S., Li M., et al. High-performance genetically targetable optical neural silencing by light-driven proton pumps. Nature 2010, 463(7277):98-102.
    • (2010) Nature , vol.463 , Issue.7277 , pp. 98-102
    • Chow, B.Y.1    Han, X.2    Dobry, A.S.3    Qian, X.4    Chuong, A.S.5    Li, M.6
  • 25
    • 48049090049 scopus 로고    scopus 로고
    • Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons
    • Douglass A.D., Kraves S., Deisseroth K., Schier A.F., Engert F. Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons. Current Biology 2008, 18(15):1133-1137.
    • (2008) Current Biology , vol.18 , Issue.15 , pp. 1133-1137
    • Douglass, A.D.1    Kraves, S.2    Deisseroth, K.3    Schier, A.F.4    Engert, F.5
  • 26
    • 33646058552 scopus 로고    scopus 로고
    • Crystal structures of archaerhodopsin-1 and -2: Common structural motif in archaeal light-driven proton pumps
    • Enami N., Yoshimura K., Murakami M., Okumura H., Ihara K., Kouyama T. Crystal structures of archaerhodopsin-1 and -2: Common structural motif in archaeal light-driven proton pumps. Journal of Molecular Biology 2006, 358(3):675-685.
    • (2006) Journal of Molecular Biology , vol.358 , Issue.3 , pp. 675-685
    • Enami, N.1    Yoshimura, K.2    Murakami, M.3    Okumura, H.4    Ihara, K.5    Kouyama, T.6
  • 27
    • 0036667739 scopus 로고    scopus 로고
    • Halorhodopsin: Light-driven ion pumping made simple?
    • Essen L.O. Halorhodopsin: Light-driven ion pumping made simple?. Current Opinion in Structural Biology 2002, 12(4):516-522.
    • (2002) Current Opinion in Structural Biology , vol.12 , Issue.4 , pp. 516-522
    • Essen, L.O.1
  • 30
    • 0025830694 scopus 로고
    • Structure-function studies of bacteriorhodopsin XV. Effects of deletions in loops B-C and E-F on bacteriorhodopsin chromophore and structure
    • Gilles-Gonzalez M.A., Engelman D.M., Khorana H.G. Structure-function studies of bacteriorhodopsin XV. Effects of deletions in loops B-C and E-F on bacteriorhodopsin chromophore and structure. Journal of Biological Chemistry 1991, 266(13):8545-8550.
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.13 , pp. 8545-8550
    • Gilles-Gonzalez, M.A.1    Engelman, D.M.2    Khorana, H.G.3
  • 31
    • 57049123832 scopus 로고    scopus 로고
    • ENpHR: A Natronomonas halorhodopsin enhanced for optogenetic applications
    • Gradinaru V., Thompson K.R., Deisseroth K. eNpHR: A Natronomonas halorhodopsin enhanced for optogenetic applications. Brain Cell Biology 2008, 36(1-4):129-139.
    • (2008) Brain Cell Biology , vol.36 , Issue.1-4 , pp. 129-139
    • Gradinaru, V.1    Thompson, K.R.2    Deisseroth, K.3
  • 32
    • 37549067797 scopus 로고    scopus 로고
    • Targeting and readout strategies for fast optical neural control in vitro and in vivo
    • Gradinaru V., Thompson K.R., Zhang F., Mogri M., Kay K., Schneider M.B., et al. Targeting and readout strategies for fast optical neural control in vitro and in vivo. Journal of Neuroscience 2007, 27(52):14231-14238.
    • (2007) Journal of Neuroscience , vol.27 , Issue.52 , pp. 14231-14238
    • Gradinaru, V.1    Thompson, K.R.2    Zhang, F.3    Mogri, M.4    Kay, K.5    Schneider, M.B.6
  • 33
    • 77950930288 scopus 로고    scopus 로고
    • Molecular and cellular approaches for diversifying and extending optogenetics
    • Gradinaru V., Zhang F., Ramakrishnan C., Mattis J., Prakash R., Diester I., et al. Molecular and cellular approaches for diversifying and extending optogenetics. Cell 2010, 141(1):154-165.
    • (2010) Cell , vol.141 , Issue.1 , pp. 154-165
    • Gradinaru, V.1    Zhang, F.2    Ramakrishnan, C.3    Mattis, J.4    Prakash, R.5    Diester, I.6
  • 34
    • 79951713532 scopus 로고    scopus 로고
    • Differential targeting of optical neuromodulators to ganglion cell soma and dendrites allows dynamic control of center-surround antagonism
    • Greenberg K.P., Pham A., Werblin F.S. Differential targeting of optical neuromodulators to ganglion cell soma and dendrites allows dynamic control of center-surround antagonism. Neuron 2011, 69(4):713-720.
    • (2011) Neuron , vol.69 , Issue.4 , pp. 713-720
    • Greenberg, K.P.1    Pham, A.2    Werblin, F.S.3
  • 35
    • 73349105935 scopus 로고    scopus 로고
    • Optical interrogation of neural circuits in Caenorhabditis elegans
    • Guo Z.V., Hart A.C., Ramanathan S. Optical interrogation of neural circuits in Caenorhabditis elegans. Nature Methods 2009, 6(12):891-896.
    • (2009) Nature Methods , vol.6 , Issue.12 , pp. 891-896
    • Guo, Z.V.1    Hart, A.C.2    Ramanathan, S.3
  • 36
    • 55849136898 scopus 로고    scopus 로고
    • Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution
    • Han X., Boyden E.S. Multiple-color optical activation, silencing, and desynchronization of neural activity, with single-spike temporal resolution. PLoS One 2007, 2(3):e299.
    • (2007) PLoS One , vol.2 , Issue.3
    • Han, X.1    Boyden, E.S.2
  • 37
    • 84862909320 scopus 로고    scopus 로고
    • A high-light sensitivity optical neural silencer: Development and application to optogenetic control of non-human primate cortex
    • Han X., Chow B.Y., Zhou H., Klapoetke N., Chuong A., Rajimehr R., et al. A high-light sensitivity optical neural silencer: Development and application to optogenetic control of non-human primate cortex. Frontiers in Systems Neuroscience 2011, 5:18.
    • (2011) Frontiers in Systems Neuroscience , vol.5 , pp. 18
    • Han, X.1    Chow, B.Y.2    Zhou, H.3    Klapoetke, N.4    Chuong, A.5    Rajimehr, R.6
  • 38
    • 65249104510 scopus 로고    scopus 로고
    • Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain
    • Han X., Qian X., Bernstein J.G., Zhou H.H., Franzesi G.T., Stern P., et al. Millisecond-timescale optical control of neural dynamics in the nonhuman primate brain. Neuron 2009, 62(2):191-198.
    • (2009) Neuron , vol.62 , Issue.2 , pp. 191-198
    • Han, X.1    Qian, X.2    Bernstein, J.G.3    Zhou, H.H.4    Franzesi, G.T.5    Stern, P.6
  • 39
    • 77950935182 scopus 로고    scopus 로고
    • Informational lesions: Optical perturbation of spike timing and neural synchrony via microbial opsin gene fusions
    • Han X., Qian X., Stern P., Chuong A.S., Boyden E.S. Informational lesions: Optical perturbation of spike timing and neural synchrony via microbial opsin gene fusions. Frontiers in Molecular Neuroscience 2009, 10.3389/neuro.02.012.2009.
    • (2009) Frontiers in Molecular Neuroscience
    • Han, X.1    Qian, X.2    Stern, P.3    Chuong, A.S.4    Boyden, E.S.5
  • 40
    • 0000948647 scopus 로고
    • The photocycle of the chloride pump halorhodopsin. I: Azide-catalyzed deprotonation of the chromophore is a side reaction of photocycle intermediates inactivating the pump
    • Hegemann P., Oesterhelt D., Steiner M. The photocycle of the chloride pump halorhodopsin. I: Azide-catalyzed deprotonation of the chromophore is a side reaction of photocycle intermediates inactivating the pump. EMBO Journal 1985, 4(9):2347-2350.
    • (1985) EMBO Journal , vol.4 , Issue.9 , pp. 2347-2350
    • Hegemann, P.1    Oesterhelt, D.2    Steiner, M.3
  • 42
    • 38049061220 scopus 로고    scopus 로고
    • Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice
    • Huber D., Petreanu L., Ghitani N., Ranade S., Hromadka T., Mainen Z., et al. Sparse optical microstimulation in barrel cortex drives learned behaviour in freely moving mice. Nature 2008, 451(7174):61-64.
    • (2008) Nature , vol.451 , Issue.7174 , pp. 61-64
    • Huber, D.1    Petreanu, L.2    Ghitani, N.3    Ranade, S.4    Hromadka, T.5    Mainen, Z.6
  • 43
    • 0033534585 scopus 로고    scopus 로고
    • Evolution of the archaeal rhodopsins: Evolution rate changes by gene duplication and functional differentiation
    • Ihara K., Umemura T., Katagiri I., Kitajima-Ihara T., Sugiyama Y., Kimura Y., et al. Evolution of the archaeal rhodopsins: Evolution rate changes by gene duplication and functional differentiation. Journal of Molecular Biology 1999, 285(1):163-174.
    • (1999) Journal of Molecular Biology , vol.285 , Issue.1 , pp. 163-174
    • Ihara, K.1    Umemura, T.2    Katagiri, I.3    Kitajima-Ihara, T.4    Sugiyama, Y.5    Kimura, Y.6
  • 44
    • 30944451943 scopus 로고    scopus 로고
    • Kinetic evaluation of photosensitivity in genetically engineered neurons expressing green algae light-gated channels
    • Ishizuka T., Kakuda M., Araki R., Yawo H. Kinetic evaluation of photosensitivity in genetically engineered neurons expressing green algae light-gated channels. Neuroscience Research 2006, 54(2):85-94.
    • (2006) Neuroscience Research , vol.54 , Issue.2 , pp. 85-94
    • Ishizuka, T.1    Kakuda, M.2    Araki, R.3    Yawo, H.4
  • 45
    • 0344845205 scopus 로고    scopus 로고
    • Proteorhodopsin in living color: Diversity of spectral properties within living bacterial cells
    • Kelemen B.R., Du M., Jensen R.B. Proteorhodopsin in living color: Diversity of spectral properties within living bacterial cells. Biochimica et Biophysica Acta 2003, 1618(1):25-32.
    • (2003) Biochimica et Biophysica Acta , vol.1618 , Issue.1 , pp. 25-32
    • Kelemen, B.R.1    Du, M.2    Jensen, R.B.3
  • 46
    • 44649186755 scopus 로고    scopus 로고
    • Screening and characterization of proteorhodopsin color-tuning mutations in Escherichia coli with endogenous retinal synthesis
    • Kim S.Y., Waschuk S.A., Brown L.S., Jung K.H. Screening and characterization of proteorhodopsin color-tuning mutations in Escherichia coli with endogenous retinal synthesis. Biochimica et Biophysica Acta 2008, 1777(6):504-513.
    • (2008) Biochimica et Biophysica Acta , vol.1777 , Issue.6 , pp. 504-513
    • Kim, S.Y.1    Waschuk, S.A.2    Brown, L.S.3    Jung, K.H.4
  • 48
    • 0034717007 scopus 로고    scopus 로고
    • Structure of the light-driven chloride pump halorhodopsin at 1.8 A resolution
    • Kolbe M., Besir H., Essen L.O., Oesterhelt D. Structure of the light-driven chloride pump halorhodopsin at 1.8 A resolution. Science 2000, 288(5470):1390-1396.
    • (2000) Science , vol.288 , Issue.5470 , pp. 1390-1396
    • Kolbe, M.1    Besir, H.2    Essen, L.O.3    Oesterhelt, D.4
  • 49
    • 44849103425 scopus 로고    scopus 로고
    • High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression
    • Kuhlman S.J., Huang Z.J. High-resolution labeling and functional manipulation of specific neuron types in mouse brain by Cre-activated viral gene expression. PLoS One 2008, 3(4):e2005.
    • (2008) PLoS One , vol.3 , Issue.4
    • Kuhlman, S.J.1    Huang, Z.J.2
  • 50
    • 44349103098 scopus 로고    scopus 로고
    • Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration
    • Lagali P.S., Balya D., Awatramani G.B., Munch T.A., Kim D.S., Busskamp V., et al. Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration. Nature Neuroscience 2008, 11(6):667-675.
    • (2008) Nature Neuroscience , vol.11 , Issue.6 , pp. 667-675
    • Lagali, P.S.1    Balya, D.2    Awatramani, G.B.3    Munch, T.A.4    Kim, D.S.5    Busskamp, V.6
  • 53
    • 0025157188 scopus 로고
    • The primary structure of a halorhodopsin from Natronobacterium pharaonis. Structural, functional and evolutionary implications for bacterial rhodopsins and halorhodopsins
    • Lanyi J.K., Duschl A., Hatfield G.W., May K., Oesterhelt D. The primary structure of a halorhodopsin from Natronobacterium pharaonis. Structural, functional and evolutionary implications for bacterial rhodopsins and halorhodopsins. Journal of Biological Chemistry 1990, 265(3):1253-1260.
    • (1990) Journal of Biological Chemistry , vol.265 , Issue.3 , pp. 1253-1260
    • Lanyi, J.K.1    Duschl, A.2    Hatfield, G.W.3    May, K.4    Oesterhelt, D.5
  • 55
    • 65549100187 scopus 로고    scopus 로고
    • Characterization of engineered channelrhodopsin variants with improved properties and kinetics
    • Lin J.Y., Lin M.Z., Steinbach P., Tsien R.Y. Characterization of engineered channelrhodopsin variants with improved properties and kinetics. Biophysical Journal 2009, 96(5):1803-1814.
    • (2009) Biophysical Journal , vol.96 , Issue.5 , pp. 1803-1814
    • Lin, J.Y.1    Lin, M.Z.2    Steinbach, P.3    Tsien, R.Y.4
  • 59
    • 0025873898 scopus 로고
    • Bacteriorhodopsin mutants containing single substitutions of serine or threonine residues are all active in proton translocation
    • Marti T., Otto H., Mogi T., Rosselet S.J., Heyn M.P., Khorana H.G. Bacteriorhodopsin mutants containing single substitutions of serine or threonine residues are all active in proton translocation. Journal of Biological Chemistry 1991, 266(11):6919-6927.
    • (1991) Journal of Biological Chemistry , vol.266 , Issue.11 , pp. 6919-6927
    • Marti, T.1    Otto, H.2    Mogi, T.3    Rosselet, S.J.4    Heyn, M.P.5    Khorana, H.G.6
  • 60
    • 33646158465 scopus 로고    scopus 로고
    • PH dependence of light-driven proton pumping by an archaerhodopsin from Tibet: Comparison with bacteriorhodopsin
    • Ming M., Lu M., Balashov S.P., Ebrey T.G., Li Q., Ding J. pH dependence of light-driven proton pumping by an archaerhodopsin from Tibet: Comparison with bacteriorhodopsin. Biophysical Journal 2006, 90(9):3322-3332.
    • (2006) Biophysical Journal , vol.90 , Issue.9 , pp. 3322-3332
    • Ming, M.1    Lu, M.2    Balashov, S.P.3    Ebrey, T.G.4    Li, Q.5    Ding, J.6
  • 61
    • 0024978461 scopus 로고
    • Structure-function studies on bacteriorhodopsin. IX. Substitutions of tryptophan residues affect protein-retinal interactions in bacteriorhodopsin
    • Mogi T., Marti T., Khorana H.G. Structure-function studies on bacteriorhodopsin. IX. Substitutions of tryptophan residues affect protein-retinal interactions in bacteriorhodopsin. Journal of Biological Chemistry 1989, 264(24):14197-14201.
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.24 , pp. 14197-14201
    • Mogi, T.1    Marti, T.2    Khorana, H.G.3
  • 62
    • 0024978498 scopus 로고
    • Structure-function studies on bacteriorhodopsin. VIII. Substitutions of the membrane-embedded prolines 50, 91, and 186: The effects are determined by the substituting amino acids
    • Mogi T., Stern L.J., Chao B.H., Khorana H.G. Structure-function studies on bacteriorhodopsin. VIII. Substitutions of the membrane-embedded prolines 50, 91, and 186: The effects are determined by the substituting amino acids. Journal of Biological Chemistry 1989, 264(24):14192-14196.
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.24 , pp. 14192-14196
    • Mogi, T.1    Stern, L.J.2    Chao, B.H.3    Khorana, H.G.4
  • 66
    • 29044433616 scopus 로고    scopus 로고
    • Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses
    • Nagel G., Brauner M., Liewald J.F., Adeishvili N., Bamberg E., Gottschalk A. Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses. Current Biology 2005, 15(24):2279-2284.
    • (2005) Current Biology , vol.15 , Issue.24 , pp. 2279-2284
    • Nagel, G.1    Brauner, M.2    Liewald, J.F.3    Adeishvili, N.4    Bamberg, E.5    Gottschalk, A.6
  • 68
    • 0033609065 scopus 로고    scopus 로고
    • Chloride concentration dependency of the electrogenic activity of halorhodopsin
    • Okuno D., Asaumi M., Muneyuki E. Chloride concentration dependency of the electrogenic activity of halorhodopsin. Biochemistry 1999, 38(17):5422-5429.
    • (1999) Biochemistry , vol.38 , Issue.17 , pp. 5422-5429
    • Okuno, D.1    Asaumi, M.2    Muneyuki, E.3
  • 69
    • 34247548430 scopus 로고    scopus 로고
    • Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections
    • Petreanu L., Huber D., Sobczyk A., Svoboda K. Channelrhodopsin-2-assisted circuit mapping of long-range callosal projections. Nature Neuroscience 2007, 10(5):663-668.
    • (2007) Nature Neuroscience , vol.10 , Issue.5 , pp. 663-668
    • Petreanu, L.1    Huber, D.2    Sobczyk, A.3    Svoboda, K.4
  • 70
    • 61349194996 scopus 로고    scopus 로고
    • The subcellular organization of neocortical excitatory connections
    • Petreanu L., Mao T., Sternson S.M., Svoboda K. The subcellular organization of neocortical excitatory connections. Nature 2009, 457(7233):1142-1145.
    • (2009) Nature , vol.457 , Issue.7233 , pp. 1142-1145
    • Petreanu, L.1    Mao, T.2    Sternson, S.M.3    Svoboda, K.4
  • 71
    • 84857086076 scopus 로고    scopus 로고
    • Optimizing two-photon activation of channelrhodopsin-2 for stimulation at cellular resolution
    • Society for Neuroscience, Washington, DC
    • Optimizing two-photon activation of channelrhodopsin-2 for stimulation at cellular resolution. Neuroscience 2008, Society for Neuroscience, Washington, DC.
    • (2008) Neuroscience
  • 72
    • 0039355490 scopus 로고    scopus 로고
    • Specific arginine and threonine residues control anion binding and transport in the light-driven chloride pump halorhodopsin
    • Rudiger M., Oesterhelt D. Specific arginine and threonine residues control anion binding and transport in the light-driven chloride pump halorhodopsin. EMBO Journal 1997, 16(13):3813-3821.
    • (1997) EMBO Journal , vol.16 , Issue.13 , pp. 3813-3821
    • Rudiger, M.1    Oesterhelt, D.2
  • 73
    • 33749837676 scopus 로고    scopus 로고
    • Light-induced activation of distinct modulatory neurons triggers appetitive or aversive learning in Drosophila larvae
    • Schroll C., Riemensperger T., Bucher D., Ehmer J., Voller T., Erbguth K., et al. Light-induced activation of distinct modulatory neurons triggers appetitive or aversive learning in Drosophila larvae. Current Biology 2006, 16(17):1741-1747.
    • (2006) Current Biology , vol.16 , Issue.17 , pp. 1741-1747
    • Schroll, C.1    Riemensperger, T.2    Bucher, D.3    Ehmer, J.4    Voller, T.5    Erbguth, K.6
  • 75
    • 0027043105 scopus 로고
    • Aspartic acid 85 in bacteriorhodopsin functions both as proton acceptor and negative counterion to the Schiff base
    • Subramaniam S., Greenhalgh D.A., Khorana H.G. Aspartic acid 85 in bacteriorhodopsin functions both as proton acceptor and negative counterion to the Schiff base. Journal of Biological Chemistry 1992, 267(36):25730-25733.
    • (1992) Journal of Biological Chemistry , vol.267 , Issue.36 , pp. 25730-25733
    • Subramaniam, S.1    Greenhalgh, D.A.2    Khorana, H.G.3
  • 76
    • 42649112394 scopus 로고    scopus 로고
    • Silencing preBotzinger complex somatostatin-expressing neurons induces persistent apnea in awake rat
    • Tan W., Janczewski W.A., Yang P., Shao X.M., Callaway E.M., Feldman J.L. Silencing preBotzinger complex somatostatin-expressing neurons induces persistent apnea in awake rat. Nature Neuroscience 2008, 11(5):538-540.
    • (2008) Nature Neuroscience , vol.11 , Issue.5 , pp. 538-540
    • Tan, W.1    Janczewski, W.A.2    Yang, P.3    Shao, X.M.4    Callaway, E.M.5    Feldman, J.L.6
  • 77
    • 0031583474 scopus 로고    scopus 로고
    • Chloride and proton transport in bacteriorhodopsin mutant D85T: Different modes of ion translocation in a retinal protein
    • Tittor J., Haupts U., Haupts C., Oesterhelt D., Becker A., Bamberg E. Chloride and proton transport in bacteriorhodopsin mutant D85T: Different modes of ion translocation in a retinal protein. Journal of Molecular Biology 1997, 271(3):405-416.
    • (1997) Journal of Molecular Biology , vol.271 , Issue.3 , pp. 405-416
    • Tittor, J.1    Haupts, U.2    Haupts, C.3    Oesterhelt, D.4    Becker, A.5    Bamberg, E.6
  • 78
    • 0029160250 scopus 로고
    • Bacteriorhodopsin mutants D85N, D85T and D85, 96N as proton pumps
    • Tittor J., Oesterhelt D., Bamberg E. Bacteriorhodopsin mutants D85N, D85T and D85, 96N as proton pumps. Biophysical Chemistry 1995, 56(1-2):153-157.
    • (1995) Biophysical Chemistry , vol.56 , Issue.1-2 , pp. 153-157
    • Tittor, J.1    Oesterhelt, D.2    Bamberg, E.3
  • 79
    • 48149105674 scopus 로고    scopus 로고
    • Neurons born in the adult dentate gyrus form functional synapses with target cells
    • Toni N., Laplagne D.A., Zhao C., Lombardi G., Ribak C.E., Gage F.H., et al. Neurons born in the adult dentate gyrus form functional synapses with target cells. Nature Neuroscience 2008, 11(8):901-907.
    • (2008) Nature Neuroscience , vol.11 , Issue.8 , pp. 901-907
    • Toni, N.1    Laplagne, D.A.2    Zhao, C.3    Lombardi, G.4    Ribak, C.E.5    Gage, F.H.6
  • 82
    • 0028869129 scopus 로고
    • Light-driven chloride ion transport by halorhodopsin from Natronobacterium pharaonis. 1. The photochemical cycle
    • Varo G., Brown L.S., Sasaki J., Kandori H., Maeda A., Needleman R., et al. Light-driven chloride ion transport by halorhodopsin from Natronobacterium pharaonis. 1. The photochemical cycle. Biochemistry 1995, 34(44):14490-14499.
    • (1995) Biochemistry , vol.34 , Issue.44 , pp. 14490-14499
    • Varo, G.1    Brown, L.S.2    Sasaki, J.3    Kandori, H.4    Maeda, A.5    Needleman, R.6
  • 83
    • 0028808334 scopus 로고
    • Light-driven chloride ion transport by halorhodopsin from Natronobacterium pharaonis. 2. Chloride release and uptake, protein conformation change, and thermodynamics
    • Varo G., Needleman R., Lanyi J.K. Light-driven chloride ion transport by halorhodopsin from Natronobacterium pharaonis. 2. Chloride release and uptake, protein conformation change, and thermodynamics. Biochemistry 1995, 34(44):14500-14507.
    • (1995) Biochemistry , vol.34 , Issue.44 , pp. 14500-14507
    • Varo, G.1    Needleman, R.2    Lanyi, J.K.3
  • 87
    • 37549071095 scopus 로고    scopus 로고
    • Structural role of bacterioruberin in the trimeric structure of archaerhodopsin-2
    • Yoshimura K., Kouyama T. Structural role of bacterioruberin in the trimeric structure of archaerhodopsin-2. Journal of Molecular Biology 2008, 375(5):1267-1281.
    • (2008) Journal of Molecular Biology , vol.375 , Issue.5 , pp. 1267-1281
    • Yoshimura, K.1    Kouyama, T.2
  • 88
    • 33749020262 scopus 로고    scopus 로고
    • Channelrhodopsin-2 and optical control of excitable cells
    • Zhang F., Wang L.P., Boyden E.S., Deisseroth K. Channelrhodopsin-2 and optical control of excitable cells. Nature Methods 2006, 3(10):785-792.
    • (2006) Nature Methods , vol.3 , Issue.10 , pp. 785-792
    • Zhang, F.1    Wang, L.P.2    Boyden, E.S.3    Deisseroth, K.4
  • 89
    • 34247222730 scopus 로고    scopus 로고
    • Multimodal fast optical interrogation of neural circuitry
    • Zhang F., Wang L.P., Brauner M., Liewald J.F., Kay K., Watzke N., et al. Multimodal fast optical interrogation of neural circuitry. Nature 2007, 446(7136):633-639.
    • (2007) Nature , vol.446 , Issue.7136 , pp. 633-639
    • Zhang, F.1    Wang, L.P.2    Brauner, M.3    Liewald, J.F.4    Kay, K.5    Watzke, N.6
  • 90
    • 57049183577 scopus 로고    scopus 로고
    • Improved expression of halorhodopsin for light-induced silencing of neuronal activity
    • Zhao S., Cunha C., Zhang F., Liu Q., Gloss B., Deisseroth K., et al. Improved expression of halorhodopsin for light-induced silencing of neuronal activity. Brain Cell Biology 2008, 36(1-4):141-154.
    • (2008) Brain Cell Biology , vol.36 , Issue.1-4 , pp. 141-154
    • Zhao, S.1    Cunha, C.2    Zhang, F.3    Liu, Q.4    Gloss, B.5    Deisseroth, K.6
  • 91
    • 79251478076 scopus 로고    scopus 로고
    • Multiwaveguide implantable probe for light delivery to sets of distributed brain targets
    • Zorzos A.N., Boyden E.S., Fonstad C.G. Multiwaveguide implantable probe for light delivery to sets of distributed brain targets. Optics Letters 2010, 35(24):4133-4135.
    • (2010) Optics Letters , vol.35 , Issue.24 , pp. 4133-4135
    • Zorzos, A.N.1    Boyden, E.S.2    Fonstad, C.G.3


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