A hypothetical model for predicting the toxicity of high aspect ratio nanoparticles (HARN)

Journal of Nanoparticle Research

Volumn 13, Issue 12, 2011, Pages 6683-6698

  Tran, C L ^a   Tantra, R ^b   Donaldson, K ^c   Stone, V ^d   Hankin, S M ^a   Ross, B ^a   Aitken, R J ^a   Jones, A D ^a  

^a INSTITUTE OF OCCUPATIONAL MEDICINE   (United Kingdom)

^b NATIONAL PHYSICAL LABORATORY   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d EDINBURGH NAPIER UNIVERSITY   (United Kingdom)

Author keywords

Carbon nanotubes; Environmental and health effects; High aspect ratio nanoparticles; Mineral fibre paradigm; Nanotoxicity

Indexed keywords

BIOLOGICAL ENVIRONMENTS; DIAMETER RATIO; DIMENSIONAL STRUCTURES; DOSE EXPOSURE; ECONOMIC IMPORTANCE; ENVIRONMENTAL AND HEALTH EFFECTS; EPIDEMIOLOGICAL STUDIES; HIGH ASPECT RATIO; HYPOTHETICAL MODELS; NANOTOXICITY; PATHOGENICITY ASSAYS; PHYSICAL DIMENSIONS; PHYSICO-CHEMICAL DATA; PHYSICOCHEMICAL PROPERTY; PREDICTIVE MODELS; PUBLIC ACCEPTANCE; PUBLIC HEALTH; REFERENCE STANDARD; RESEARCH DIRECTIONS; TOXICOLOGICAL EFFECTS;

ASPECT RATIO; BIOASSAY; CARBON NANOTUBES; FORECASTING; NANOPARTICLES; RESEARCH;

TOXICITY;

ASBESTOS; HIGH ASPECT RATIO NANOPARTICLE; NANOPARTICLE; NANOROD; NANOTUBE; NANOWIRE; UNCLASSIFIED DRUG;

ARTICLE; BIOASSAY; BIOPERSISTENCE; DISSOLUTION; GEOMETRY; NONBIOLOGICAL MODEL; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TOXICITY TESTING;

EID: 84857063484     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-011-0575-9     Document Type: Article

References (127)

1. Ahrenkiel SP, Yu PR et al (2008) Nanoparticle shape and configuration analysis by transmission electron tomography. J Microsc-Oxf 230 (3):382-387 (Pubitemid 351747860)
2. Alkilany AM, Murphy CJ (2010) Toxicity and cellular uptake of gold nanoparticles: what we have learned so far? J Nano-part Res 12 (7):2313-2333
3. Alkilany AM, Nagaria PK et al (2009) Cellular uptake and cytotoxicity of gold nanorods: molecular origin of cyto-toxicity and surface effects. Small 5 (6):701-708
4. Arbiol J, Rossinyol E, Cabot A, Peiro F, Cornet A, Morante JR (2004) TEM 3D tomography of noble metal nanowires growth inside SiO/sub 2/mesoporous aggregates. In: Nanoparticles and nanowire building blocks-synthesis, processing, characterization and theory, pp 61-65 (Pubitemid 40157546)
5. Arenal R, Bruno P et al (2007) Diamond nanowires and the insulator-metal transition in ultrananocrystalline diamond films. Phys Rev B 75 (19):11
6. Atashbar MZ, Singamaneni S (2005) Room temperature gas sensor based on metallic nanowires. Sens Act B Chem 111:13-21 (Pubitemid 41354840)
7. Atsuro Y, Yoshinori S, Yoshinobu N, Satoru Y, Takao K, Masanobu S, Takao K, Masanobu S, Takao K, Tsukasa A, Motohiro UO, Fumlo W, Kazuyuki T (2005) Biological behavior of hat-stacked carbon nanofibers in the subcutaneous tissue in rats. Nano lett 5 (1):157-161
8. Barth HG (1984) Modern methods of particle size analysis, vol 73. Wiley-Interscience, NJ, USA
9. Berger A, Christiansen S, Stelzner T, Andra G (2007) Oxidized Si-nanowire-analytical TEM investigations. In: Proceedings microscopy conference, Saarbriicken, Germany
10. Bernstein DM, Riego-Sintes JMR (1999) Methods for the determination of the hazardous properties for human health of man made mineral fibers. European Commission Joint Research Centre, Institute for Health and Consumer Protection, Unit: Toxicology and Chemical Substances, European Chemicals Bureau, EUR 18748 EN, April. http://ecb.ei.jrc.it/DOCUMENTS/Testing-Methods/mmmfweb. pdf
11. Bernstein DM, Sintes JMR et al (2001) Biopersistence of synthetic mineral fibers as a predictor of chronic intraperito-neal injection tumor response in rats. Inhalation Toxicol 13 (10):851-875 (Pubitemid 33020393)
12. Bhalerao GM, Waugh S et al (2007) SEM and Raman spec-troscopy of multiwalled carbon nanotubes grown by novel technique of ash supported catalysts. J Nanosci Nano-technol 7 (6):1860-1866
13. Biro LP (2000) Scanning probe microscopy (STM, AFM) investigation of carbon nanotubes. In: Pavesi L, Buzaneva E (eds) Frontiers of nano-optoelectronic systems. NATO science series II-mathematics, physics and chemistry, vol 6. Springer, The Netherlands, pp 405-420
14. Biswas SKS, Sandra B, Vajtai R, Bingqing W, Parker A, Schowalter LJ, Ajayan PM (2003) AFM-based electrical characterization of nano-structures. In: Symposium Mater Res. Soc. Symposium Proceedings 738: 331-337
15. Bogner A, Jouneau PH et al (2007) A history of scanning electron microscopy developments: towards "wet-STEM" imaging. Micron 38 (4):390-401 (Pubitemid 46149334)
16. Braga PC, Ricci D (2004) Atomic force microscopy: biomedical methods and applications. Humana Press, Totowa, NJ
17. Brown DM, Kinloch IA, Bangertc U, Windle AH, Walterd DM, Walker GS, Scotchford CA, Donaldson K, Stone V (2007) An in vitro study of the potential of carbon nanotubes and nanofibers to induce inflammation mediators and frustrated phagocytosis. Carbon 45 (9):1743-1756 (Pubitemid 47069251)
18. Chiriac H, Moga AE, Gherasimu C (2006) Preparation and magnetic properties of Fe and Ni based nanoparticles and nanowires. In: International semiconductor conference, Sinaia, Romania (IEEE Cat. No. 06TH8867) vol 1, pp 53-56
19. Cho JH, Ok-Kyoung K, Gon-Ho K (2004) Ion irradiation effects on the structural deformation of multi-walled carbon nanotubes. In: IEEE conference record-abstracts. 31st IEEE international conference on plasma science (IEEE Cat. No.04CH37537), pp 468
20. Cwiertny DM, Hunter GJ, Pettibone JM, Scherer MM, Grassian VH (2009) Surface chemistry and dissolution of a-FeOOH nanorods and microrods: environmental implications of size-dependent interactions with oxalate. J Phys Chem 113 (6):2175-2186
21. Decossas S, Cappello G et al (2001) Interaction forces between carbon nanotubes and an AFM tip. Europhys Lett 53 (6): 742-748
22. Donaldson K, Aitken R et al (2006) Carbon nanotubes: a review of their properties in relation to pulmonary toxicology and workplace safety. Toxicol Sci 92 (1):5-22 (Pubitemid 43985785)
23. Driscoll KE, Costa DL et al (2000) Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: uses and limitations. Toxicol Sci 55 (1):24-35 (Pubitemid 30252432)
24. Edwards MA, Williams CG et al (2009) Scanning ion conductance microscopy: a model for experimentally realistic conditions and image interpretation. Anal Chem 81 (11): 4482-4492
25. Egerton RF (2003) New techniques in electron energy-loss spectroscopy and energy-filtered imaging. Micron 34 (3-5): 127-139 (Pubitemid 37240489)
26. Elgrabli D, Floriani M et al (2008) Biodistribution and clearance of instilled carbon nanotubes in rat lung. Part Fibre Toxicol 5:13
27. Ellinger-Ziegelbauer H, Pauluhn J (2009) Pulmonary toxicity of multi-walled carbon nanotubes (Baytubes (R)) relative to alpha-quartz following a single 6 h inhalation exposure of rats and a 3 months post-exposure period. Toxicology 266 (1-3):16-29
28. Fu J, Dixson R, Orji G, Vorburger T, Nguyen CV (2005) Linewidth measurement from a stitched AFM image. In: AIP conference proceedings, vol 788, pp 421-426 (Pubitemid 44555896)
29. Gellein K, Hoel S et al (2009) The colony formation assay as an indicator of carbon nanotube toxicity examined in three cell lines. Nanotoxicology 3 (3):215-221
30. Gibbs GW (2001) Health effects associated with mining and milling chrysotile asbestos in Quebec and the role of tremolite. Can Mineralog 165-175
31. Golberg D, Bando Y et al (2002) Preparation of aligned multi-walled BN and B/C/N nanotubular arrays and their characterization using HRTEM, EELS and energy-filtered TEM. Phys B Condens Matter 323 (1-4):60-66 (Pubitemid 35018992)
32. Gonzalez D, Nasibulin AG et al (2006) Spontaneous charging of single-walled carbon nanotubes: a novel strategy for the selective substrate deposition of individual tubes at ambient temperature. Chem Mater 18 (21):5052-5057 (Pubitemid 44663547)
33. Gratton SEA, Ropp PA et al (2008) The effect of particle design on cellular internalization pathways. Proc Natl Acad Sci USA 105 (33):11613-11618
34. Hesterberg TW, Hart GA (2000) Lung biopersistence and in vitro dissolution rate predict the pathogenic potential of synthetic vitreous fibers. Inhalation Toxicol 12:91-97
35. Hiemenz PC, Rajagopalan R (1997) Principles of colloid and surface chemistry, vol 14 of undergraduate chemistry, 3rd edn. CRC Press, Boca Raton
36. Hillegass JM, Shukla A et al (2010) Assessing nanotoxicity in cells in vitro. Wiley Interdiscip Rev Nanomed Nanobio-technol 2 (3):219-231
37. Hondroulis E, Liu C et al (2010) Whole cell based electrical impedance sensing approach for a rapid nanotoxicity assay. Nanotechnology 21 (31):9
38. Horváth L, Magrez A, Golberg D, Zhi C, Bando Y, Smajda R, Horváth E, Forró L, Schwaller B (2011) In vitro investigation of the cellular toxicity of boron nitride nanotubes. ACS Nano 5 (5): 3800-3810
39. Hu XK, Cook S et al (2010) In vitro evaluation of cytotoxicity of engineered carbon nanotubes in selected human cell lines. Sci Total Environ 408 (8):1812-1817
40. Hutchison JL, Routkevitch D, Albu-Yaron A, Moskovitz M, Nayak RR (1997) TEM and HREM structuralstudiesofnon-lithographically-produced CdS nanowires. In: Microscopy of semiconducting materials 1997. Proceedings of the royal microscopical society conference, pp 389-392 (Pubitemid 128013346)
41. Ishibashi A, Nakashima N (2006) Individual dissolution of single-walled carbon nanotubes in aqueous solutions of steroid or sugar compounds and their Raman and near-IR spectral properties. Chem A Eur J 12 (29):7595-7602 (Pubitemid 44569852)
42. Jin CH, Wang JY et al (2005) In situ studies of electron field emission of single carbon nanotubes inside the TEM. Carbon 43 (5):1026-1031
43. Journeay WS, Suri SS, Fenniri H, Singh B (2008) High-aspect ratio nanoparticles in nanotoxicology. Integr Environ Assess Manage 4 (1):128-129
44. Julien DC, Richardson CC et al (2010) In vitro proliferating cell models to study cytotoxicity of silica nanowires. Nanomed-Nanotechnol Biol Med 6 (1):84-92
45. Jurkschat K, Wilkins SJ et al (2006) Multiwalled carbon nano-tubes with molybdenum dioxide nanoplugs-new chemical nanoarchitectures by electrochemical modification. Small 2 (1):95-98 (Pubitemid 43198001)
46. Kagan VE, Tyurina YY et al (2006) Direct and indirect effects of single walled carbon nanotubes on RAW 264.7 macro-phages: role of iron. Toxicol Lett 165 (1):88-100 (Pubitemid 43867182)
47. Kamino T, Yaguchi T et al (2005) In situ high temperature TEM observation of interaction between multi-walled carbon nanotube and in situ deposited gold nano-particles. J Electron Microsc 54 (5):461-465 (Pubitemid 43011845)
48. Kawasaki SMY, Yokomae T, Nojima Y, Okino F, Touhara H, Kataura H (2005) XRD and TEM study of high pressure treated single-walled carbon nanotubes and C/sub 60/-peapods. Carbon 43 (1):37-45
49. Kim JS, Song KS et al (2010) Determination of cytotoxicity attributed to multiwall carbon nanotubes (MWCNT) in normal human embryonic lung cell (WI-38) line. J Toxicol Environ Health-A-Curr Issues 73 (21-22):1521-1529
50. Kirk S, Skepper J et al (2009) Application of environmental scanning electron microscopy to determine biological surface structure. J Microsc Oxf 233 (2):205-224
51. Koyama S, Endo M et al (2006) Role of systemic T-cells and histopathological aspects after subcutaneous implantation of various carbon nanotubes in mice. Carbon 44 (6):1079-1092 (Pubitemid 43202165)
52. Kulkarni JS, Daly B, Ziegler KJ, Crowley T, Erts D, Polyakov B, Morris MA, Holmes JD (2005) NSTI nanotechnology conference and trade show. NSTI Nanotech 2005, vol 2, pp 627-629
53. Lam CW, James JT et al (2006) A review of carbon nanotube toxicity and assessment of potential occupational and environmental health risks. Crit Rev Toxicol 36 (3): 189-217
54. Li Z, Hulderman T et al (2007) Cardiovascular effects of pulmonary exposure to single-wall carbon nanotubes. Environ Health Perspect 115 (3):377-382 (Pubitemid 46554435)
55. Liu XY, Hurt RH et al (2010) Biodurability of single-walled carbon nanotubes depends on surface functionalization. Carbon 48 (7):1961-1969
56. Losic D, Shapter JG et al (2005) Fabrication of gold nanorod arrays by templating from porous alumina. Nanotechnol-ogy 16 (10):2275-2281 (Pubitemid 41376168)
57. 2-based nanofilaments. Acs Nano 3 (8):2274-2280
58. Ma-Hock L, Treumann S et al (2009) Inhalation toxicity of multiwall carbon nanotubes in rats exposed for 3 months. Toxicol Sci 112 (2):468-481
59. Malloy A, Carr B (2006) Nanoparticle tracking analysis-the Halo (TM) system. Part Part Syst Charact 23 (2):197-204 (Pubitemid 44342614)
60. Manning CB, Vallyathan V, Mossman BT (2002) Diseases caused by asbestos: mechanisms of injury and disease development. Int Immunopharmacol 2 (2-3):191-200 (Pubitemid 34075410)
61. Manolaki P, Häusler I, Kirmse H, Neumann W, Smalc J, Ko-zubowski J (2007) TEM investigations of (In, Ga) N/GaN laser structures. In: Proceedings microscopy conference, pp 324-325
62. Mao GZ, Dong WF et al (2004) Synthesis of copper sulfide nanorod arrays on molecular templates. Nano Lett 4 (2): 249-252
63. Mikhaylova M, Toprak M, Kim DK, Zhang Y, Muhammed M (2005) Nanowire formation by electrodeposition in modified nanoporous polycrystalline anodic alumina templates. In: Nanoparticulate materials. Symposium, Materials Research Society Symposium Proceedings, vol 704, pp 155-160
64. Mongillo J (2007) Nanotechnology science 101. Greenwood Publishing Group, Praeger
65. Monteiro-Riviere NA, Nemanich RJ et al (2005) Multi-walled carbon nanotube interactions with human epidermal keratinocytes. Toxicol Lett 155 (3):377-384 (Pubitemid 40093001)
66. Montes-Burgos I, Walczyk D et al (2010) Characterisation of nanoparticle size and state prior to nanotoxicological studies. J Nanopart Res 12 (1):47-53
67. Murray AR, Kisin E et al (2009) Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes. Toxicology 257 (3):161-171
68. Nejo H, Maeda Y et al (2007) The topological structures of the debundled single-walled carbon nanotubes on a grid. Mater Trans 48 (4):711-717 (Pubitemid 46848000)
69. 2 nanorods. Toxicology 279 (1-3):167-175
70. Nysten B, Fretigny C, Cuenot S (2005) Elastic modulus of nanomaterials: resonant contact-AFM measurement and reduced-size effects (invited paper). In: Proceedings of the SPIE-the international society for optical engineering, vol 5766 (1), pp 78-88 (Pubitemid 41381681)
71. O'Connell MJ (2006) Carbon nanotubes: properties and applications. CRC Press, Boston
72. Ohgai T, Mizumoto M et al (2007) Electrochemical fabrication of metallic nanowires and metal oxide nanopores. Mater Manuf Proc 22 (4):440-443 (Pubitemid 46572965)
73. Oshima Y, Mouri K et al (2003) Development of a miniature STM holder for study of electronic conductance of metal nanowires in UHV-TEM. Surf Sci 531 (3):209-216
74. Otsuka Y, Naitoh Y et al (2002) A nano tester: a new technique for nanoscale electrical characterization by point-contact current-imaging atomic force microscopy. Jpn J Appl Phys Part 2 Lett 41 (7A):L742-L744 (Pubitemid 34964314)
75. Panessa-Warren BJ, Warren JB et al (2006) Biological cellular response to carbon nanoparticle toxicity. J Phys-Condens Matter 18 (33):S2185-S2201 (Pubitemid 44192070)
76. Patra CR, Moneim SSA et al (2009) In vivo toxicity studies of europium hydroxide nanorods in mice. Toxicol Appl Pharmacol 240 (1):88-98
77. Pauluhn J (2009) Subchronic 13-week inhalation exposure of rats to multiwalled carbon nanotubes: toxic effects are determined by density of agglomerate structures, not fibrillar structures. Toxicol Sci 113 (1):226-242
78. Perepichka DF, Wudl F et al (2004) The dissolution of carbon nanotubes in aniline, revisited. J Mater Chem 14 (18): 2749-2752
79. Pettinger B (2010) Single-molecule surface-and tip-enhanced Raman spectroscopy. Mole Phys 108 (16):2039-2059
80. Poland CA, Duffin R et al (2008) Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 3 (7): 423-428
81. Porter AE, Gass M et al (2007) Visualizing the uptake of C-60 to the cytoplasm and nucleus of human monocyte-derived macrophage cells using energy-filtered transmission electron microscopy and electron tomography. Environ Sci Technol 41 (8):3012-3017 (Pubitemid 46626435)
82. Prescott WV, Schwartz AI (2008) Nanorods, nanotubes, and nanomaterials research progress. Nova Publishers, New York
83. Reimer L (1998) Scanning electron microscopy: physics of image formation and microanalysis, vol 45, 2nd edn. Springer, New York
84. Reimer L, Kohl H (2008) Transmission electron microscopy: physics of image formation. Springer, New York
85. Ribak J, Ribak G (2008) Human health effects associated with the commercial use of grunerite asbestos (amosite): Paterson, NJ; Tyler, TX; Uxbridge, UK. Regul Toxicol Pharmacol 52 (1): S82-S90
86. Ryman-Rasmussen JP, Cesta MF et al (2009) Inhaled carbon nanotubes reach the subpleural tissue in mice. Nat Nano-technol 4 (11):747-751
87. Sanchez-Garcia MA, Grandal J et al (2006) Epitaxial growth and characterization of InN nanorods and compact layers on silicon substrates. Phys Status Solidi B-Basic Solid State Phys 243 (7):1490-1493 (Pubitemid 44013950)
88. Sau TK, Murphy CJ (2004) Seeded and non-seeded methods to make metallic nanorods and nanowires in aqueous solution. In: Quantum dots, nanoparticles and nanowires symposium. Materials Research Society Symposium Proceedings, vol 789, pp 203-212
89. Schujman SB, Vajtai R, Shusterman Y, Biswas S, Dewhirst B, Schowalter LJ, Wei BQ, Ajayan PM (2002) AFM-based surface potential measurements on carbon nanotubes. In: Making functional materials with nanotubes. Symposium, Materials Research Society Symposium Proceedings vol 706, pp 377-382
90. Schwarz MI, King TE (1993) Interstitial lung disease, 2nd edn. CRC Press, Boston
91. Shelley T (2006) Nanotechnology: new promises, new dangers. Zed Books, London
92. Shen KCS, Xu H, Rogelj S, Jiang Y, Dewald J, Pietrass T (2005) Single-walled carbon nanotube purification, pelletization, and surfactant-assisted dispersion: a combined TEM and resonant micro-Raman spectroscopy study. J Phys Chem B 109 (10):4455-4463
93. Shimotani K, Watanabe H, Manabe C, Shigematsu T, Shimizu M (1999) Triple-probe atomic force microscope: measuring a carbon nanotube/DNA MIS-FET. In: Spatially resolved characterization of local phenomena in materials and nanostructures. Symposium, Materials Research Society Symposium Proceedings, vol 738, pp 289-292
94. Shvedova AA, Castranova V et al (2003) Exposure to carbon nanotube material: assessment of nanotube cytotoxicity using human keratinocyte cells. J Toxicol Environ Health A 66 (20):1909-1926 (Pubitemid 37352634)
95. Shvedova AA, Kisin ER, Mercer R, Murray AR, Johnson VJ, Potapovich AI, Tyurina YY, Gorelik O, Arepalli S, Schwegler-Berry D, Hubbs AF, Antonini J, Evans DE, Ku B, Ramsey D, Maynard A, Kagan VE, Castranova V, Baron P (2005) Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. AJP Lung Cell Mole Physiol 289:L698-L708 (Pubitemid 41504399)
96. Shvedova AA, Kisin E et al (2008) Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis. Am J Physiol Lung Cell Mole Physiol 295 (4):L552-L565
97. Sigle W (2005) Analytical transmission electron microscopy. Ann Rev Mater Res 35:239-314 (Pubitemid 41310686)
98. Simon-Deckers A, Loo S et al (2009) Size-, composition-and shape-dependent toxicological impact of metal oxide nanoparticles and carbon nanotubes toward bacteria. Environ Sci Technol 43 (21):8423-8429
99. Sivakumar K, Lu S, Panchapakesan B (2004) Metallic and semiconducting nanowires from single wall carbon nano-tubes. In: Nanoparticles and nanowire building blocks-synthesis, processing, characterization and theory, pp 341-346 (Pubitemid 40157588)
100. Sohaebuddin SK, Thevenot PT et al (2010) Nanomaterial cytotoxicity is composition, size, and cell type dependent. Part Fibre Toxicol 7:17
101. Sonnichsen C, Donald A (1997) Studies on living cells using environmental scanning electron microscopy. Eur J Cell Biol 74:102
102. Stella GM (2011) Carbon nanotubes and pleural damage: perspectives of nanosafety in the light of asbestos experience. Biointerphases 6:1-17
103. Stephan C, Nguyen TP, de la Chapelle ML, Lefrant S, Journet C, Bernier P (2000) Characterization of single walled carbon nanotubes. PMMA Synth Metals 108 (2):139-149 (Pubitemid 30536607)
104. Sugawara A, Haga Y, Nittono O (1995) Self-alignment of metallic nanowires in CaF/sub 2/-based composite films grown on stepped NaCl substrates. J Magn Magn Mater 156 (1-3): 151-152
105. Suzuki SBC, Zhou O (1998) In situ TEM and EELS studies of alkali-metal intercalation with single-walled carbon nanotubes. Chem Phys Lett 285 (3-4):230-234 (Pubitemid 128180272)
106. Takagi A, Hirose A et al (2008) Induction of mesothelioma in p53± mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 33 (1):105-116 (Pubitemid 351340768)
107. Tanaka I, Yamato H et al (2001) Biopersistence of man-made fibers by animal inhalation experiments in recent reports. Ind Health 39 (2):114-118 (Pubitemid 32452458)
108. Tarantola M, Schneider D et al (2009) Cytotoxicity of metal and semiconductor nanoparticles indicated by cellular mi-cromotility. Acs Nano 3 (1):213-222
109. Thurnherr T, Brandenberger C et al (2011) A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro. Toxicol Lett 200 (3):176-186
110. Tombler TW, Zhou CW et al (2000) Reversible electromechanical characteristics of carbon nanotubes under local-probe manipulation. Nature 405 (6788):769-772 (Pubitemid 30407843)
111. Tran CL, Hankin SM, Ross B, Aitken RJ, Jones AD, Donaldson K, Stone V, Tantra R (2008) HARN report considers health risks of high aspect ratio nanomaterials in relation to asbestos
112. Vickerman JC, Gilmore I (2009) Surface analysis: the principal techniques, 2nd edn. Wiley, Chichester
113. Vincent JH (2007) Aerosol sampling: science, standards, instrumentation and applications Chicester. Wiley, Chichester
114. Wang YW, Liang CH et al (2001) Preparation and characterization of ordered semiconductor CdO nanowire arrays. J Mater Sci Lett 20 (18):1687-1689 (Pubitemid 33075757)
115. 3 nanorods. Mater Res Bull 37 (3):495-502
116. xS nanorods prepared through hydrothermal route. Opt Mater 27 (3):453-458
117. WHO (World Health Organization) (1997) Determination of airborne fibre number concentrations: a recommended method by phase contrast, Optical Microscopy. WHO, Geneva
118. WHO (1985) WHO/Euro reference scheme. Scand J Work Environ Health 11:123-129
119. Xu R (2000) Particle characterization: light scattering methods. Springer, New York
120. Xue SH, Wang ZD (2006) Metal nanorod arrays and their magnetic properties. Mater Sci Eng B Solid State Mater Adv Technol 135 (1):74-77 (Pubitemid 44633647)
121. Yao N, Wang ZL (2005) Handbook of microscopy for nano-technology. Springer Science & Business, Berlin
122. Yuan ZY, Zhou WZ et al (2003) Electron beam irradiation effect on nanostructured molecular sieve catalysts. J Electron Spectrosc Relat Phenom 129 (2-3):189-194
123. Zeng XB, Liao XB, Diao HW, Hu ZH, Xu YY, Zhang SB, Chen cY, Chen WD, Kong GL (2003) Polymorphous silicon nanowires synthesised by plasma-enhanced chemical vapor deposition. In: Quantum confined semiconductor nanostructures. Materials Research Society Symposium Proceedings, vol 737, pp 667-672
124. Zhang JX, Shi GQ et al (2003) Electrochemical fabrication of polythiophene film coated metallic nanowire arrays. J Mater Sci 38 (11):2423-2427
125. Zhang L, Li ZR et al (2006) Influence of a top crust of entangled nanotubes on the structure of vertically aligned forests of single-walled carbon nanotubes. Chem Mater 18 (23): 5624-5629 (Pubitemid 44865801)
126. Zhang LW, Zeng LL et al (2007) Biological interactions of functionalized single-wall carbon nanotubes in human epidermal keratinocytes. Int J Toxicol 26 (2):103-113 (Pubitemid 46514921)
127. Zhang YY, Wang B et al (2011) Influences of acid-treated multiwalled carbon nanotubes on fibroblasts: proliferation, adhesion, migration, and wound healing. Ann Biomed Eng 39 (1):414-426