Forty percent methionine restriction lowers DNAmethylation, complex i ROS generation, and oxidative damage to mtDNA and mitochondrial proteins in rat heart

Journal of Bioenergetics and Biomembranes

Volumn 43, Issue 6, 2011, Pages 699-708

  Sanchez Roman, Ines ^a   Gomez, Alexia ^a   Gomez, Jose ^a   Suarez, Henar ^a   Sanchez, Carlota ^a   Naudi, Alba ^b   Ayala, Victoria ^b   Portero Otin, Manuel ^a   Lopez Torres, Monica ^b   Pamplona, Reinald ^b   Barja, Gustavo ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b UNIVERSITY OF LLEIDA   (Spain)

Author keywords

Dietary restriction; DNA methylation; Free radicals; Methionine; Oxidative damage

Indexed keywords

APOPTOSIS INDUCING FACTOR; GENOMIC DNA; METHIONINE; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; DNA DAMAGE; DNA METHYLATION; ELECTRON TRANSPORT; HEART; LONGEVITY; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE STRESS; RAT; WISTAR RAT;

ANIMALS; APOPTOSIS INDUCING FACTOR; DNA DAMAGE; DNA METHYLATION; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT COMPLEX I; LONGEVITY; MALE; METHIONINE; MITOCHONDRIA, HEART; OXIDATION-REDUCTION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; TIME FACTORS;

RATTUS; RATTUS NORVEGICUS; RODENTIA;

EID: 84857062258     PISSN: 0145479X     EISSN: 15736881     Source Type: Journal    
DOI: 10.1007/s10863-011-9389-9     Document Type: Article

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