Impairment of immunoproteasome function by β5i/lmp7 subunit deficiency results in severe enterovirus myocarditis

PLoS Pathogens

Volumn 7, Issue 9, 2011, Pages

  Opitz, Elisa ^a   Koch, Annett ^a   Klingel, Karin ^b   Schmidt, Frank ^c   Prokop, Stefan ^a   Rahnefeld, Anna ^a   Sauter, Martina ^b   Heppner, Frank L ^a   Völker, Uwe ^c   Kandolf, Reinhard ^b   Kuckelkorn, Ulrike ^a   Stangl, Karl ^a   Krüger, Elke ^a   Kloetzel, Peter M ^a   Voigt, Antje ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c UNIVERSITY OF GREIFSWALD   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA5I PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LMP7 PROTEIN; PROTEASOME; UNCLASSIFIED DRUG; POLYUBIQUITIN;

ACUTE DISEASE; ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL DEATH; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; COXSACKIE VIRUS B; DISEASE EXACERBATION; DISEASE SEVERITY; HEART MUSCLE CELL; HEART MUSCLE INJURY; IMMUNE RESPONSE; INFLAMMATION; INFLAMMATORY CELL; MOUSE; NONHUMAN; PROTEIN AGGREGATION; PROTEIN HOMEOSTASIS; T LYMPHOCYTE; UBIQUITINATION; VIRUS LOAD; VIRUS MYOCARDITIS; ANIMAL; COXSACKIE VIRUS INFECTION; ENTEROVIRUS; IMMUNOLOGY; MYOCARDITIS; PATHOLOGY; PROTEIN SUBUNIT; VIROLOGY;

COXSACKIEVIRUS; ENTEROVIRUS; IPS; MUS;

ANIMALS; APOPTOSIS; COXSACKIEVIRUS INFECTIONS; ENTEROVIRUS B, HUMAN; MICE; MYOCARDITIS; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SUBUNITS;

EID: 80053457072     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1002233     Document Type: Article

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