Brain metastases: Pathobiology and emerging targeted therapies

Acta Neuropathologica

Volumn 123, Issue 2, 2012, Pages 205-222

  Preusser, Matthias ^a   Capper, David ^b   Ilhan Mutlu, Aysegül ^a   Berghoff, Anna Sophie ^c   Birner, Peter ^a   Bartsch, Rupert ^a   Marosi, Christine ^a   Zielinski, Christoph ^a   Mehta, Minesh P ^d   Winkler, Frank ^e   Wick, Wolfgang ^e   Von Deimling, Andreas ^b  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d NORTHWESTERN UNIVERSITY   (United States)

^e UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Brain metastases; Cancer; Molecular targets; Pathobiology; Therapy

Indexed keywords

ANAPLASTIC LYMPHOMA KINASE; ANTINEOPLASTIC AGENT; B RAF KINASE; B RAF KINASE INHIBITOR; BEVACIZUMAB; CAPECITABINE; CILENGITIDE; CYCLOOXYGENASE 2; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DABRAFENIB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GSK 461364A; HEPARANASE; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; INIPARIB; INTEGRIN; LAPATINIB; MATRIX METALLOPROTEINASE; POLO LIKE KINASE 1; SELECTIN; SORAFENIB; SUNITINIB; THALIDOMIDE; TRASTUZUMAB; UNCLASSIFIED DRUG; VATALANIB; VELIPARIB; VEMURAFENIB; Z 222584;

ADVANCED CANCER; ASTROCYTE; BLOOD BRAIN BARRIER; BRAIN HEMORRHAGE; BRAIN METASTASIS; BREAST CANCER; CANCER COMBINATION CHEMOTHERAPY; CELL ADHESION; CELL INTERACTION; CELL INVASION; CELL SURVIVAL; DISEASE MARKER; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFICACY; EPIDERMAL GROWTH FACTOR RECEPTOR GENE; EXTRACELLULAR MATRIX; GLIOBLASTOMA; HUMAN; KIDNEY CANCER; LUNG CANCER; LUNG NON SMALL CELL CANCER; MELANOMA; MICROENVIRONMENT; MICROGLIA; MOLECULARLY TARGETED THERAPY; NONHUMAN; ONCOGENE; ONCOGENE NEU; PARACRINE SIGNALING; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SINGLE DRUG DOSE; TUMOR CLASSIFICATION; TUMOR VASCULARIZATION;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN NEOPLASMS; DRUG DELIVERY SYSTEMS; HUMANS; NEOVASCULARIZATION, PATHOLOGIC; SIGNAL TRANSDUCTION;

EID: 84857034419     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0933-9     Document Type: Review

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