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Volumn 70, Issue 21, 2010, Pages 8662-8673

Cediranib/AZD2171 inhibits bone and brain metastasis in a preclinical model of advanced prostate cancer

Author keywords

[No Author keywords available]

Indexed keywords

CEDIRANIB; VASCULOTROPIN;

EID: 78449306244     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-1435     Document Type: Article
Times cited : (44)

References (27)
  • 1
    • 0036674501 scopus 로고    scopus 로고
    • Dissemination and growth of cancer cells in metastatic sites
    • Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002; 2:563-72.
    • (2002) Nat Rev Cancer , vol.2 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    MacDonald, I.C.3
  • 2
    • 47949089077 scopus 로고    scopus 로고
    • VEGF-targeted therapy: Mechanisms of anti-tumour activity
    • Ellis LM, Hicklin DJ. VEGF-targeted therapy: mechanisms of anti-tumour activity. Nat Rev Cancer 2008;8:579-91.
    • (2008) Nat Rev Cancer , vol.8 , pp. 579-591
    • Ellis, L.M.1    Hicklin, D.J.2
  • 3
    • 60649116477 scopus 로고    scopus 로고
    • Silencing or fueling metastasis with VEGF inhibitors: Antiangiogenesis revisited
    • Loges S, Mazzone M, Hohensinner P, Carmeliet P. Silencing or fueling metastasis with VEGF inhibitors: antiangiogenesis revisited. Cancer Cell 2009;15:167-70.
    • (2009) Cancer Cell , vol.15 , pp. 167-170
    • Loges, S.1    Mazzone, M.2    Hohensinner, P.3    Carmeliet, P.4
  • 5
    • 60649106195 scopus 로고    scopus 로고
    • Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
    • Paez-Ribes M, Allen E, Hudock J, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis. Cancer Cell 2009;15:220-31.
    • (2009) Cancer Cell , vol.15 , pp. 220-231
    • Paez-Ribes, M.1    Allen, E.2    Hudock, J.3
  • 9
    • 33846149645 scopus 로고    scopus 로고
    • AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
    • Batchelor TT, Sorensen AG, di Tomaso E, et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 2007; 11:83-95.
    • (2007) Cancer Cell , vol.11 , pp. 83-95
    • Batchelor, T.T.1    Sorensen, A.G.2    Di Tomaso, E.3
  • 10
    • 60649116273 scopus 로고    scopus 로고
    • Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: Impact on local control and patient survival
    • Narayana A, Kelly P, Golfinos J, et al. Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival. J Neurosurg 2009;110:173-80.
    • (2009) J Neurosurg , vol.110 , pp. 173-180
    • Narayana, A.1    Kelly, P.2    Golfinos, J.3
  • 11
    • 35648970538 scopus 로고    scopus 로고
    • Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone
    • Yin J, Pollock C, Tracy K, et al. Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone. Mol Cell Biol 2007;27: 7538-50.
    • (2007) Mol Cell Biol , vol.27 , pp. 7538-7550
    • Yin, J.1    Pollock, C.2    Tracy, K.3
  • 12
    • 67349264881 scopus 로고    scopus 로고
    • Noninvasive imaging of the functional effects of anti-VEGF therapy on tumor cell extravasation and regional blood volume in an experimental brain metastasis model
    • JuanYin J, Tracy K, Zhang L, et al. Noninvasive imaging of the functional effects of anti-VEGF therapy on tumor cell extravasation and regional blood volume in an experimental brain metastasis model. Clin Exp Metastasis 2009;26:403-14.
    • (2009) Clin Exp Metastasis , vol.26 , pp. 403-414
    • JuanYin, J.1    Tracy, K.2    Zhang, L.3
  • 13
    • 77950433110 scopus 로고    scopus 로고
    • Human CD34+ cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature
    • Lavazza C, Carlo-Stella C, Giacomini A, et al. Human CD34+ cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature. Blood 2010;115:2231-40.
    • (2010) Blood , vol.115 , pp. 2231-2240
    • Lavazza, C.1    Carlo-Stella, C.2    Giacomini, A.3
  • 14
    • 20144370978 scopus 로고    scopus 로고
    • AZD2171: A highly potent, orally bioavailable, vascular endothelial growth factor receptor- 2 tyrosine kinase inhibitor for the treatment of cancer
    • Wedge SR, Kendrew J, Hennequin LF, et al. AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor- 2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res 2005;65:4389-400.
    • (2005) Cancer Res , vol.65 , pp. 4389-4400
    • Wedge, S.R.1    Kendrew, J.2    Hennequin, L.F.3
  • 15
    • 0038476608 scopus 로고    scopus 로고
    • Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
    • Bergers G, Song S, Meyer-Morse N, Bergsland E, Hanahan D. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 2003;111: 1287-95.
    • (2003) J Clin Invest , vol.111 , pp. 1287-1295
    • Bergers, G.1    Song, S.2    Meyer-Morse, N.3    Bergsland, E.4    Hanahan, D.5
  • 16
    • 67649091076 scopus 로고    scopus 로고
    • VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer
    • Gerstner ER, Duda DG, di Tomaso E, et al. VEGF inhibitors in the treatment of cerebral edema in patients with brain cancer. Nat Rev Clin Oncol 2009;6:229-36.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 229-236
    • Gerstner, E.R.1    Duda, D.G.2    Di Tomaso, E.3
  • 17
    • 23944515733 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptors in osteoclast differentiation and function
    • Aldridge SE, Lennard TW, Williams JR, Birch MA. Vascular endothelial growth factor receptors in osteoclast differentiation and function. Biochem Biophys Res Commun 2005;335:793-8.
    • (2005) Biochem Biophys Res Commun , vol.335 , pp. 793-798
    • Aldridge, S.E.1    Lennard, T.W.2    Williams, J.R.3    Birch, M.A.4
  • 18
    • 40149083563 scopus 로고    scopus 로고
    • Guidance on the use of bisphosphonates in solid tumours: Recommendations of an international expert panel
    • Aapro M, Abrahamsson PA, Body JJ, et al. Guidance on the use of bisphosphonates in solid tumours: recommendations of an international expert panel. Ann Oncol 2008;19:420-32.
    • (2008) Ann Oncol , vol.19 , pp. 420-432
    • Aapro, M.1    Abrahamsson, P.A.2    Body, J.J.3
  • 19
    • 47949099628 scopus 로고    scopus 로고
    • Modes of resistance to anti-angiogenic therapy
    • Bergers G, Hanahan D. Modes of resistance to anti-angiogenic therapy. Nat Rev Cancer 2008;8:592-603.
    • (2008) Nat Rev Cancer , vol.8 , pp. 592-603
    • Bergers, G.1    Hanahan, D.2
  • 20
    • 0033822622 scopus 로고    scopus 로고
    • Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular co-option
    • Rubenstein JL, Kim J, Ozawa T, et al. Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular co-option. Neoplasia 2000;2:306-14.
    • (2000) Neoplasia , vol.2 , pp. 306-314
    • Rubenstein, J.L.1    Kim, J.2    Ozawa, T.3
  • 21
    • 3342959040 scopus 로고    scopus 로고
    • Vascular endothelial growth factor expression promotes the growth of breast cancer brain metastases in nude mice
    • Kim LS, Huang S, Lu W, Lev DC, Price JE. Vascular endothelial growth factor expression promotes the growth of breast cancer brain metastases in nude mice. Clin Exp Metastasis 2004;21:107-18.
    • (2004) Clin Exp Metastasis , vol.21 , pp. 107-118
    • Kim, L.S.1    Huang, S.2    Lu, W.3    Lev, D.C.4    Price, J.E.5
  • 22
    • 4644304024 scopus 로고    scopus 로고
    • Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option
    • Leenders WP, Kusters B, Verrijp K, et al. Antiangiogenic therapy of cerebral melanoma metastases results in sustained tumor progression via vessel co-option. Clin Cancer Res 2004;10:6222-30.
    • (2004) Clin Cancer Res , vol.10 , pp. 6222-6230
    • Leenders, W.P.1    Kusters, B.2    Verrijp, K.3
  • 23
    • 67649240336 scopus 로고    scopus 로고
    • The vascular basement membrane as "soil" in brain metastasis
    • Carbonell WS, Ansorge O, Sibson N, Muschel R. The vascular basement membrane as "soil" in brain metastasis. PLoS One 2009;4:e5857.
    • (2009) PLoS One , vol.4
    • Carbonell, W.S.1    Ansorge, O.2    Sibson, N.3    Muschel, R.4
  • 24
  • 25
    • 33846798106 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms
    • Aird WC. Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ Res 2007;100:158-73.
    • (2007) Circ Res , vol.100 , pp. 158-173
    • Aird, W.C.1
  • 26
    • 33846029123 scopus 로고    scopus 로고
    • A perivascular niche for brain tumor stem cells
    • Calabrese C, Poppleton H, Kocak M, et al. A perivascular niche for brain tumor stem cells. Cancer Cell 2007;11:69-82.
    • (2007) Cancer Cell , vol.11 , pp. 69-82
    • Calabrese, C.1    Poppleton, H.2    Kocak, M.3
  • 27
    • 69849104865 scopus 로고    scopus 로고
    • The leukemic stem cell niche: Current concepts and therapeutic opportunities
    • Lane SW, Scadden DT, Gilliland DG. The leukemic stem cell niche: current concepts and therapeutic opportunities. Blood 2009;114: 1150-7.
    • (2009) Blood , vol.114 , pp. 1150-1157
    • Lane, S.W.1    Scadden, D.T.2    Gilliland, D.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.