Integrin β4 signaling promotes mammary tumor cell adhesion to brain microvascular endothelium by inducing ErbB2-mediated secretion of VEGF

Annals of Biomedical Engineering

Volumn 39, Issue 8, 2011, Pages 2223-2241

  Fan, Jie ^a,b   Cai, Bin ^a   Zeng, Min ^a   Hao, Yanyan ^c   Giancotti, Filippo G ^c   Fu, Bingmei M ^a  

^a City College of New York   (United States)

^b BEIHANG UNIVERSITY   (China)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Endothelial permeability; Endothelial VEGF receptor; ErbB2; Intercellular junctions; Laminin 5; VE cadherin; ZO 1

Indexed keywords

ENDOTHELIAL PERMEABILITY; ENDOTHELIAL VEGF RECEPTOR; ERBB2; INTERCELLULAR JUNCTION; LAMININ-5; VE-CADHERIN; ZO-1;

BLOOD VESSELS; BUILDINGS; CELL ADHESION; ENDOTHELIAL CELLS; MONOLAYERS; SIGNALING; TUMORS;

ADHESION;

BETA4 INTEGRIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBB2 PROTEIN, MOUSE; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR;

ANIMAL; ARTICLE; BIOSYNTHESIS; BRAIN; CELL ADHESION; CELL LINE; EXPERIMENTAL NEOPLASM; FEMALE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MICROCIRCULATION; MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ANIMALS; BRAIN; CELL ADHESION; CELL LINE, TRANSFORMED; CELL LINE, TUMOR; ENDOTHELIUM, VASCULAR; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; INTEGRIN BETA4; MAMMARY NEOPLASMS, ANIMAL; MICE; MICROCIRCULATION; RECEPTOR, ERBB-2; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 80051546588     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-011-0321-6     Document Type: Article

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