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Volumn 11, Issue , 2012, Pages

Expression and extracellular release of a functional anti-trypanosome Nanobody ® in Sodalis glossinidius, a bacterial symbiont of the tsetse fly

Author keywords

Expression; Functional; Glossina; Nanobody; Paratransgenesis; Sodalis glossinidius; Symbiont

Indexed keywords

BACTERIUM ANTIBODY; EPITOPE; NANOBODY; UNCLASSIFIED DRUG; VARIANT SURFACE GLYCOPROTEIN; GLYCOPROTEIN; HYBRID PROTEIN; PROTOZOAL PROTEIN; PROTOZOON ANTIBODY; SIGNAL PEPTIDE;

EID: 84857016910     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/1475-2859-11-23     Document Type: Article
Times cited : (62)

References (39)
  • 1
    • 0033081754 scopus 로고    scopus 로고
    • Tissue tropism, transmission and expression of foreign genes in vivo in midgut symbionts of tsetse flies
    • 10.1046/j.1365-2583.1999.810125.x, 9927181
    • Cheng Q, Aksoy S. Tissue tropism, transmission and expression of foreign genes in vivo in midgut symbionts of tsetse flies. Insect Mol Biol 1999, 8:125-132. 10.1046/j.1365-2583.1999.810125.x, 9927181.
    • (1999) Insect Mol Biol , vol.8 , pp. 125-132
    • Cheng, Q.1    Aksoy, S.2
  • 2
    • 0027736544 scopus 로고
    • Genetic transformation and phylogeny of bacterial symbionts from tsetse
    • 10.1111/j.1365-2583.1993.tb00113.x, 8269090
    • Beard CB, O'Neill SL, Mason P, Mandelco L, Woese CR, Tesh RB, et al. Genetic transformation and phylogeny of bacterial symbionts from tsetse. Insect Mol Biol 1993, 1:123-131. 10.1111/j.1365-2583.1993.tb00113.x, 8269090.
    • (1993) Insect Mol Biol , vol.1 , pp. 123-131
    • Beard, C.B.1    O'Neill, S.L.2    Mason, P.3    Mandelco, L.4    Woese, C.R.5    Tesh, R.B.6
  • 3
    • 0023355327 scopus 로고
    • In vitro cultivation of rickettsia-like-organisms from Glossina spp
    • Welburn SC, Maudlin I, Ellis DS. In vitro cultivation of rickettsia-like-organisms from Glossina spp. Ann Trop Med Parasitol 1987, 81:331-335.
    • (1987) Ann Trop Med Parasitol , vol.81 , pp. 331-335
    • Welburn, S.C.1    Maudlin, I.2    Ellis, D.S.3
  • 4
    • 0035843993 scopus 로고    scopus 로고
    • Commensal host-bacterial relationships in the gut
    • 10.1126/science.1058709, 11352068
    • Hooper LV, Gordon JI. Commensal host-bacterial relationships in the gut. Science 2001, 292:1115-1118. 10.1126/science.1058709, 11352068.
    • (2001) Science , vol.292 , pp. 1115-1118
    • Hooper, L.V.1    Gordon, J.I.2
  • 6
    • 0031006487 scopus 로고    scopus 로고
    • Prevention of insect-borne disease: an approach using transgenic symbiotic bacteria
    • 10.1073/pnas.94.7.3274, 20359, 9096383
    • Durvasula RV, Gumbs A, Panackal A, Kruglov O, Aksoy S, Merrifield RB, et al. Prevention of insect-borne disease: an approach using transgenic symbiotic bacteria. Proc Natl Acad Sci USA 1997, 94:3274-3278. 10.1073/pnas.94.7.3274, 20359, 9096383.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3274-3278
    • Durvasula, R.V.1    Gumbs, A.2    Panackal, A.3    Kruglov, O.4    Aksoy, S.5    Merrifield, R.B.6
  • 7
    • 79960109154 scopus 로고    scopus 로고
    • Secretion of anti-Plasmodium effector proteins from a natural Pantoea agglomerans isolate by using PelB and HlyA secretion signals
    • 10.1128/AEM.00514-11, 3127683, 21602368
    • Bisi DC, Lampe DJ. Secretion of anti-Plasmodium effector proteins from a natural Pantoea agglomerans isolate by using PelB and HlyA secretion signals. Appl Environ Microbiol 2011, 77:4669-4675. 10.1128/AEM.00514-11, 3127683, 21602368.
    • (2011) Appl Environ Microbiol , vol.77 , pp. 4669-4675
    • Bisi, D.C.1    Lampe, D.J.2
  • 8
    • 0035940468 scopus 로고    scopus 로고
    • Tsetse immune responses and trypanosome transmission: implications for the development of tsetse-based strategies to reduce trypanosomiasis
    • 10.1073/pnas.221363798, 60108, 11592981
    • Hao Z, Kasumba I, Lehane MJ, Gibson WC, Kwon J, Aksoy S. Tsetse immune responses and trypanosome transmission: implications for the development of tsetse-based strategies to reduce trypanosomiasis. Proc Natl Acad Sci USA 2001, 98:12648-12653. 10.1073/pnas.221363798, 60108, 11592981.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 12648-12653
    • Hao, Z.1    Kasumba, I.2    Lehane, M.J.3    Gibson, W.C.4    Kwon, J.5    Aksoy, S.6
  • 9
    • 0036009126 scopus 로고    scopus 로고
    • Immunopeptides in the defense reactions of Glossina morsitans to bacterial and Trypanosoma brucei brucei infections
    • 10.1016/S0965-1748(02)00029-2, 11886771
    • Boulanger N, Brun R, Ehret-Sabatier L, Kunz C, Bulet P. Immunopeptides in the defense reactions of Glossina morsitans to bacterial and Trypanosoma brucei brucei infections. Insect Biochem Mol Biol 2002, 32:369-375. 10.1016/S0965-1748(02)00029-2, 11886771.
    • (2002) Insect Biochem Mol Biol , vol.32 , pp. 369-375
    • Boulanger, N.1    Brun, R.2    Ehret-Sabatier, L.3    Kunz, C.4    Bulet, P.5
  • 10
    • 0242307124 scopus 로고    scopus 로고
    • Proventriculus (cardia) plays a crucial role in immunity in tsetse fly (Diptera: Glossinidiae)
    • 10.1016/j.ibmb.2003.07.001, 14563366
    • Hao Z, Kasumba I, Aksoy S. Proventriculus (cardia) plays a crucial role in immunity in tsetse fly (Diptera: Glossinidiae). Insect Biochem Mol Biol 2003, 33:1155-1164. 10.1016/j.ibmb.2003.07.001, 14563366.
    • (2003) Insect Biochem Mol Biol , vol.33 , pp. 1155-1164
    • Hao, Z.1    Kasumba, I.2    Aksoy, S.3
  • 11
    • 12544255946 scopus 로고    scopus 로고
    • An antimicrobial peptide with trypanocidal activity characterized from Glossina morsitans morsitans
    • 10.1016/j.ibmb.2004.10.007, 15681221
    • Hu Y, Aksoy S. An antimicrobial peptide with trypanocidal activity characterized from Glossina morsitans morsitans. Insect Biochem Mol Biol 2005, 35:105-115. 10.1016/j.ibmb.2004.10.007, 15681221.
    • (2005) Insect Biochem Mol Biol , vol.35 , pp. 105-115
    • Hu, Y.1    Aksoy, S.2
  • 12
    • 2342638313 scopus 로고    scopus 로고
    • Cationic antimicrobial peptide killing of African trypanosomes and Sodalis glossinidius, a bacterial symbiont of the insect vector of sleeping sickness
    • 10.1089/153036603322662165, 14733670
    • Haines LR, Hancock RE, Pearson TW. Cationic antimicrobial peptide killing of African trypanosomes and Sodalis glossinidius, a bacterial symbiont of the insect vector of sleeping sickness. Vector Borne Zoonotic Dis 2003, 3:175-186. 10.1089/153036603322662165, 14733670.
    • (2003) Vector Borne Zoonotic Dis , vol.3 , pp. 175-186
    • Haines, L.R.1    Hancock, R.E.2    Pearson, T.W.3
  • 13
    • 6544263842 scopus 로고    scopus 로고
    • Expression of a functional antibody fragment in the gut of Rhodnius prolixus via transgenic bacterial symbiont Rhodococcus rhodnii
    • 10.1046/j.1365-2915.1999.00175.x, 10484156
    • Durvasula RV, Gumbs A, Panackal A, Kruglov O, Taneja J, Kang AS, et al. Expression of a functional antibody fragment in the gut of Rhodnius prolixus via transgenic bacterial symbiont Rhodococcus rhodnii. Med Vet Entomol 1999, 13:115-119. 10.1046/j.1365-2915.1999.00175.x, 10484156.
    • (1999) Med Vet Entomol , vol.13 , pp. 115-119
    • Durvasula, R.V.1    Gumbs, A.2    Panackal, A.3    Kruglov, O.4    Taneja, J.5    Kang, A.S.6
  • 14
    • 0025162270 scopus 로고
    • A comparison of strategies to stabilize immunoglobulin Fv-fragments
    • 10.1021/bi00458a002, 2110478
    • Glockshuber R, Malia M, Pfitzinger I, Pluckthun A. A comparison of strategies to stabilize immunoglobulin Fv-fragments. Biochemistry 1990, 29:1362-1367. 10.1021/bi00458a002, 2110478.
    • (1990) Biochemistry , vol.29 , pp. 1362-1367
    • Glockshuber, R.1    Malia, M.2    Pfitzinger, I.3    Pluckthun, A.4
  • 15
    • 0027332881 scopus 로고
    • An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability
    • 10.1093/protein/6.8.989, 8309948
    • Whitlow M, Bell BA, Feng SL, Filpula D, Hardman KD, Hubert SL, et al. An improved linker for single-chain Fv with reduced aggregation and enhanced proteolytic stability. Protein Eng 1993, 6:989-995. 10.1093/protein/6.8.989, 8309948.
    • (1993) Protein Eng , vol.6 , pp. 989-995
    • Whitlow, M.1    Bell, B.A.2    Feng, S.L.3    Filpula, D.4    Hardman, K.D.5    Hubert, S.L.6
  • 17
    • 0035715877 scopus 로고    scopus 로고
    • Single domain camel antibodies: current status
    • Muyldermans S. Single domain camel antibodies: current status. J Biotechnol 2001, 74:277-302.
    • (2001) J Biotechnol , vol.74 , pp. 277-302
    • Muyldermans, S.1
  • 18
    • 80052341911 scopus 로고    scopus 로고
    • A case of convergence: why did a simple alternative to canonical antibodies arise in sharks and camels?
    • 10.1371/journal.pbio.1001120, 3149040, 21829328
    • Flajnik MF, Deschacht N, Muyldermans S. A case of convergence: why did a simple alternative to canonical antibodies arise in sharks and camels?. PLoS Biol 2011, 9:e1001120. 10.1371/journal.pbio.1001120, 3149040, 21829328.
    • (2011) PLoS Biol , vol.9
    • Flajnik, M.F.1    Deschacht, N.2    Muyldermans, S.3
  • 20
    • 10644228142 scopus 로고    scopus 로고
    • Efficient cancer therapy with a nanobody-based conjugate
    • 10.1158/0008-5472.CAN-03-3935, 15087403
    • Cortez-Retamozo V, Backmann N, Senter PD, Wernery U, De BP, Muyldermans S, et al. Efficient cancer therapy with a nanobody-based conjugate. Cancer Res 2004, 64:2853-2857. 10.1158/0008-5472.CAN-03-3935, 15087403.
    • (2004) Cancer Res , vol.64 , pp. 2853-2857
    • Cortez-Retamozo, V.1    Backmann, N.2    Senter, P.D.3    Wernery, U.4    De, B.P.5    Muyldermans, S.6
  • 21
    • 36849056018 scopus 로고    scopus 로고
    • Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens
    • 10.1016/j.jim.2007.10.005, 17996887
    • Saerens D, Stijlemans B, Baral TN, Nguyen Thi GT, Wernery U, Magez S, et al. Parallel selection of multiple anti-infectome Nanobodies without access to purified antigens. J Immunol Methods 2008, 329:138-150. 10.1016/j.jim.2007.10.005, 17996887.
    • (2008) J Immunol Methods , vol.329 , pp. 138-150
    • Saerens, D.1    Stijlemans, B.2    Baral, T.N.3    Nguyen Thi, G.T.4    Wernery, U.5    Magez, S.6
  • 22
    • 0036182644 scopus 로고    scopus 로고
    • Single-domain antibody fragments with high conformational stability
    • 2373476, 11847273
    • Dumoulin M, Conrath K, Van MA, Meersman F, Heremans K, Frenken LG, et al. Single-domain antibody fragments with high conformational stability. Protein Sci 2002, 11:500-515. 2373476, 11847273.
    • (2002) Protein Sci , vol.11 , pp. 500-515
    • Dumoulin, M.1    Conrath, K.2    Van, M.A.3    Meersman, F.4    Heremans, K.5    Frenken, L.G.6
  • 23
    • 0030767656 scopus 로고    scopus 로고
    • Selection and identification of single domain antibody fragments from camel heavy-chain antibodies
    • 10.1016/S0014-5793(97)01062-4, 9323027
    • Arbabi GM, Desmyter A, Wyns L, Hamers R, Muyldermans S. Selection and identification of single domain antibody fragments from camel heavy-chain antibodies. FEBS Lett 1997, 414:521-526. 10.1016/S0014-5793(97)01062-4, 9323027.
    • (1997) FEBS Lett , vol.414 , pp. 521-526
    • Arbabi, G.M.1    Desmyter, A.2    Wyns, L.3    Hamers, R.4    Muyldermans, S.5
  • 24
    • 9144220168 scopus 로고    scopus 로고
    • Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm
    • Stijlemans B, Conrath K, Cortez-Retamozo V, Van XH, Wyns L, Senter P, et al. Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm. J Biol Chem 2004, 279:1256-1261.
    • (2004) J Biol Chem , vol.279 , pp. 1256-1261
    • Stijlemans, B.1    Conrath, K.2    Cortez-Retamozo, V.3    Van, X.H.4    Wyns, L.5    Senter, P.6
  • 25
    • 2642559479 scopus 로고    scopus 로고
    • Self-assembly and type III protein export of the bacterial flagellum
    • 10.1159/000077865, 15170399
    • Minamino T, Namba K. Self-assembly and type III protein export of the bacterial flagellum. J Mol Microbiol Biotechnol 2004, 7:5-17. 10.1159/000077865, 15170399.
    • (2004) J Mol Microbiol Biotechnol , vol.7 , pp. 5-17
    • Minamino, T.1    Namba, K.2
  • 26
    • 23644433830 scopus 로고    scopus 로고
    • Extracellular secretion of polypeptides using a modified Escherichia coli flagellar secretion apparatus
    • 10.1038/nbt1077, 15806100
    • Majander K, Anton L, Antikainen J, Lang H, Brummer M, Korhonen TK, et al. Extracellular secretion of polypeptides using a modified Escherichia coli flagellar secretion apparatus. Nat Biotechnol 2005, 23:475-481. 10.1038/nbt1077, 15806100.
    • (2005) Nat Biotechnol , vol.23 , pp. 475-481
    • Majander, K.1    Anton, L.2    Antikainen, J.3    Lang, H.4    Brummer, M.5    Korhonen, T.K.6
  • 27
    • 56149106746 scopus 로고    scopus 로고
    • Quorum sensing primes the oxidative stress response in the insect endosymbiont Sodalis glossinidius
    • Pontes MH, Babst M, Lochhead R, Oakeson K, Smith K, Dale C. Quorum sensing primes the oxidative stress response in the insect endosymbiont Sodalis glossinidius. PLoS One 2008, 3:3541.
    • (2008) PLoS One , vol.3 , pp. 3541
    • Pontes, M.H.1    Babst, M.2    Lochhead, R.3    Oakeson, K.4    Smith, K.5    Dale, C.6
  • 28
    • 25844514728 scopus 로고    scopus 로고
    • Preparative expression of secreted proteins in bacteria: status report and future prospects
    • 10.1016/j.copbio.2005.07.008, 16095898
    • Georgiou G, Segatori L. Preparative expression of secreted proteins in bacteria: status report and future prospects. Curr Opin Biotechnol 2005, 16:538-545. 10.1016/j.copbio.2005.07.008, 16095898.
    • (2005) Curr Opin Biotechnol , vol.16 , pp. 538-545
    • Georgiou, G.1    Segatori, L.2
  • 29
    • 0030271490 scopus 로고    scopus 로고
    • Secretion of recombinant proteins by Gram-negative bacteria
    • 10.1016/S0958-1669(96)80053-X, 8939628
    • Sandkvist M, Bagdasarian M. Secretion of recombinant proteins by Gram-negative bacteria. Curr Opin Biotechnol 1996, 7:505-511. 10.1016/S0958-1669(96)80053-X, 8939628.
    • (1996) Curr Opin Biotechnol , vol.7 , pp. 505-511
    • Sandkvist, M.1    Bagdasarian, M.2
  • 30
    • 0036204976 scopus 로고    scopus 로고
    • Genetic design for facilitated production and recovery of recombinant proteins in Escherichia coli
    • 10.1042/BA20010099, 11916451
    • Jonasson P, Liljeqvist S, Nygren PA, Stahl S. Genetic design for facilitated production and recovery of recombinant proteins in Escherichia coli. Biotechnol Appl Biochem 2002, 35:91-105. 10.1042/BA20010099, 11916451.
    • (2002) Biotechnol Appl Biochem , vol.35 , pp. 91-105
    • Jonasson, P.1    Liljeqvist, S.2    Nygren, P.A.3    Stahl, S.4
  • 31
    • 3042660198 scopus 로고    scopus 로고
    • Secretory and extracellular production of recombinant proteins using Escherichia coli
    • 10.1007/s00253-004-1559-9, 14966662
    • Choi JH, Lee SY. Secretory and extracellular production of recombinant proteins using Escherichia coli. Appl Microbiol Biotechnol 2004, 64:625-635. 10.1007/s00253-004-1559-9, 14966662.
    • (2004) Appl Microbiol Biotechnol , vol.64 , pp. 625-635
    • Choi, J.H.1    Lee, S.Y.2
  • 32
    • 79551489027 scopus 로고    scopus 로고
    • Functional analysis of the twin-arginine translocation pathway in Sodalis glossinidius, a bacterial symbiont of the tsetse fly
    • 10.1128/AEM.02379-10, 3028725, 21148698
    • De Vooght L, Caljon G, Coosemans M, Van den Abbeele J. Functional analysis of the twin-arginine translocation pathway in Sodalis glossinidius, a bacterial symbiont of the tsetse fly. Appl Environ Microbiol 2011, 77:1132-1134. 10.1128/AEM.02379-10, 3028725, 21148698.
    • (2011) Appl Environ Microbiol , vol.77 , pp. 1132-1134
    • De Vooght, L.1    Caljon, G.2    Coosemans, M.3    Van den Abbeele, J.4
  • 33
    • 33747738604 scopus 로고    scopus 로고
    • Selection and optimization of proteolytically stable llama single-domain antibody fragments for oral immunotherapy
    • 10.1007/s00253-005-0300-7, 16450109
    • Harmsen MM, Van Solt CB, Van Zijderveld-Van Bemmel AM, Niewold TA, Van Zijderveld FG. Selection and optimization of proteolytically stable llama single-domain antibody fragments for oral immunotherapy. Appl Microbiol Biotechnol 2006, 72:544-551. 10.1007/s00253-005-0300-7, 16450109.
    • (2006) Appl Microbiol Biotechnol , vol.72 , pp. 544-551
    • Harmsen, M.M.1    Van Solt, C.B.2    Van Zijderveld-Van Bemmel, A.M.3    Niewold, T.A.4    Van Zijderveld, F.G.5
  • 34
    • 79959851947 scopus 로고    scopus 로고
    • High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis
    • 10.1371/journal.ppat.1002072, 3116811, 21698216
    • Stijlemans B, Caljon G, Natesan SK, Saerens D, Conrath K, Perez-Morga D, et al. High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis. PLoS Pathog 2011, 7:e1002072. 10.1371/journal.ppat.1002072, 3116811, 21698216.
    • (2011) PLoS Pathog , vol.7
    • Stijlemans, B.1    Caljon, G.2    Natesan, S.K.3    Saerens, D.4    Conrath, K.5    Perez-Morga, D.6
  • 35
    • 0034858690 scopus 로고    scopus 로고
    • Development of improved versatile broad-host-range vectors for use in methylotrophs and other Gram-negative bacteria
    • Marx CJ, Lidstrom ME. Development of improved versatile broad-host-range vectors for use in methylotrophs and other Gram-negative bacteria. Microbiology 2001, 147:2065-2075.
    • (2001) Microbiology , vol.147 , pp. 2065-2075
    • Marx, C.J.1    Lidstrom, M.E.2
  • 36
    • 0024292736 scopus 로고
    • Assembly of a functional immunoglobulin Fv fragment in Escherichia coli
    • 10.1126/science.3285470, 3285470
    • Skerra A, Pluckthun A. Assembly of a functional immunoglobulin Fv fragment in Escherichia coli. Science 1988, 240:1038-1041. 10.1126/science.3285470, 3285470.
    • (1988) Science , vol.240 , pp. 1038-1041
    • Skerra, A.1    Pluckthun, A.2
  • 37
    • 84858275285 scopus 로고    scopus 로고
    • Analysis of blood-brain barrier permeability of monovalent Nanobodies using microdialysis
    • doi: 10.1111/j.1476-5381.2011.01723.x
    • Caljon G, Caveliers V, Lahoutte T, Stijlemans B, Ghassabeh GH, Van Den Abbeele J, et al. Analysis of blood-brain barrier permeability of monovalent Nanobodies using microdialysis. Br J Pharmacol 2012, doi: 10.1111/j.1476-5381.2011.01723.x.
    • (2012) Br J Pharmacol
    • Caljon, G.1    Caveliers, V.2    Lahoutte, T.3    Stijlemans, B.4    Ghassabeh, G.H.5    Van Den Abbeele, J.6
  • 38
    • 73449124061 scopus 로고    scopus 로고
    • Improved Models of Mini Anion Exchange Centrifugation Technique (mAECT) and Modified Single Centrifugation (MSC) for sleeping sickness diagnosis and staging
    • 10.1371/journal.pntd.0000471, 2775158, 19936296
    • Buscher P, Mumba ND, Kabore J, Lejon V, Robays J, Jamonneau V, et al. Improved Models of Mini Anion Exchange Centrifugation Technique (mAECT) and Modified Single Centrifugation (MSC) for sleeping sickness diagnosis and staging. PLoS Negl Trop Dis 2009, 3:e471. 10.1371/journal.pntd.0000471, 2775158, 19936296.
    • (2009) PLoS Negl Trop Dis , vol.3
    • Buscher, P.1    Mumba, N.D.2    Kabore, J.3    Lejon, V.4    Robays, J.5    Jamonneau, V.6
  • 39
    • 79956088640 scopus 로고    scopus 로고
    • Trypanosoma brucei gambiense: HMI-9 medium containing methylcellulose and human serum supports the continuous axenic in vitro propagation of the bloodstream form
    • 10.1016/j.exppara.2011.02.018, 21354143
    • Van RN, Pyana PP, Deborggraeve S, Buscher P, Claes F. Trypanosoma brucei gambiense: HMI-9 medium containing methylcellulose and human serum supports the continuous axenic in vitro propagation of the bloodstream form. Exp Parasitol 2011, 128:285-290. 10.1016/j.exppara.2011.02.018, 21354143.
    • (2011) Exp Parasitol , vol.128 , pp. 285-290
    • Van, R.N.1    Pyana, P.P.2    Deborggraeve, S.3    Buscher, P.4    Claes, F.5


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