Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies: African trypanosomes as paradigm

Journal of Biological Chemistry

Volumn 279, Issue 2, 2004, Pages 1256-1261

  Stijlemans, Benoit ^a   Conrath, Katja ^a   Cortez Retamozo, Virna ^a   Van Xong, Hoang ^a,c   Wyns, Lode ^a   Senter, Peter ^b   Revets, Hilde ^a   De Baetselier, Patrick ^a   Muyldermans, Serge ^a   Magez, Stefan ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b SEATTLE GENETICS INC   (United States)

^c UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; CARBOHYDRATES; IMMUNOLOGY; MOLECULAR BIOLOGY;

IMMUNE RESPONSES;

ANTIBODIES;

ANTIBODY; IMMUNOGLOBULIN HEAVY CHAIN;

ADOPTIVE TRANSFER; AFRICAN TRYPANOSOMIASIS; ANIMAL CELL; ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIGENIC VARIATION; ARTICLE; EPITOPE MAPPING; GENE TARGETING; GENETIC CONSERVATION; IMMUNE RESPONSE; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; TARGET CELL;

ANIMALS; ANTIGENIC VARIATION; ANTIGENS; ANTIGENS, PROTOZOAN; BETA-LACTAMASES; CARBOHYDRATES; CONCANAVALIN A; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES; FLOW CYTOMETRY; GENE LIBRARY; MICROSCOPY, FLUORESCENCE; PEPTIDE LIBRARY; PRODRUGS; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS; TRYPANOSOMA; TRYPANOSOMIASIS; VARIANT SURFACE GLYCOPROTEINS, TRYPANOSOMA;

ANIMALIA; CAMELUS DROMEDARIUS; PROTOZOA;

EID: 9144220168     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M307341200     Document Type: Article

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