Tissue-specific alterations of methyl group metabolism with DNA hypermethylation in the Zucker (type 2) diabetic fatty rat

Diabetes/Metabolism Research and Reviews

Volumn 28, Issue 2, 2012, Pages 123-131

  Williams, Kelly T ^a   Schalinske, Kevin L ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

Diabetes; DNA methylation; GNMT; Methyl group metabolism; ZDF rat

Indexed keywords

BETAINE HOMOCYSTEINE METHYLTRANSFERASE; CYSTATHIONINE BETA SYNTHASE; GENOMIC DNA; GLYCINE METHYLTRANSFERASE; HOMOCYSTEINE; MESSENGER RNA; METHIONINE SYNTHASE; METHYL GROUP; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVITY; ENZYME INDUCTION; GENE EXPRESSION; HYPERGLYCEMIA; IMMUNOBLOTTING; KIDNEY; LIVER; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; TISSUE SPECIFICITY; ZUCKER DIABETIC FATTY RAT;

5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE S-METHYLTRANSFERASE; ANIMALS; CYSTATHIONINE BETA-SYNTHASE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; GLYCINE N-METHYLTRANSFERASE; HOMOCYSTEINE; KIDNEY; LIVER; MALE; ORGAN SPECIFICITY; RATS; RATS, ZUCKER;

EID: 84856977834     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.1281     Document Type: Article

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