Identification of SNPs in the FASN gene and their effect on fatty acid milk composition in Holstein cattle

Livestock Science

Volumn 144, Issue 3, 2012, Pages 281-284

  Matsumoto, Hirokazu ^a   Inada, Satoshi ^a   Kobayashi, Eiji ^b   Abe, Tsuyoshi ^b   Hasebe, Hiroyuki ^b   Sasazaki, Shinji ^a   Oyama, Kenji ^a   Mannen, Hideyuki ^a  

^a KOBE UNIVERSITY   (Japan)

^b NATIONAL LIVESTOCK BREEDING CENTER   (Japan)

Author keywords

FASN; Fatty acid content; Holstein; Milk; SNP

Indexed keywords

BOS;

EID: 84856966963     PISSN: 18711413     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.livsci.2011.12.003     Document Type: Article

References (19)

1. Abe T., Saburi J., Hasebe H., Nakagawa T., Misumi S., Nade T., Nakajima H., Shoji N., Kobayashi M., Kobayashi E. Novel mutations of the FASN gene and their effect on fatty acid composition in Japanese Black beef. Biochem. Genet. 2009, 47:397-411.
2. Chakravarty B., Gu Z., Chirala S.S., Wakil S.J., Quiocho F.A. Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:15567-15572.
3. Folch J., Lees M., Stanley G.H.S. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 1957, 226:487-509.
4. Haug A., Høstmark A.T., Harstad O.M. Bovine milk in human nutrition-a review. Lipids Health Dis. 2007, 6:25.
5. Koletzko B., Aggett P.J., Bindels J.G., Bung P., Ferré P., Gil A., Lentze M.J., Roberfroid M., Strobel S. Growth, development and differentiation: a functional food science approach. Br. J. Nutr. 1998, 80(Suppl 1):S5-S45.
6. Mannen H. Identification and utilization of genes associated with beef qualities. Anim. Sci. J. 2011, 82:1-7.
7. Massaro M., Carluccio M.A., De Caterina R. Direct vascular antiatherogenic effects of oleic acid: a clue to the cardioprotective effects of the Mediterranean diet. Cardiologia 1999, 44:507-513.
8. Masuko T. Lipid. Nutritional Science of Dairy Cattle (in Japanese), Dairy Japan, Tokyo 1999, 95-96. T. Masuko (Ed.).
9. Morris C.A., Cullen N.G., Glass B.C., Hyndman D.L., Manley T.R., Hickey S.M., McEwan J.C., Pitchford W.S., Bottema C.D., Lee M.A. Fatty acid synthase effects on bovine adipose fat and milk fat. Mamm. Genome. 2007, 18:64-74.
10. Narukami T., Sasazaki S., Oyama K., Nogi T., Taniguchi M., Mannen H. Effect of DNA polymorphisms related to fatty acid composition in adipose tissue of Holstein cattle. Anim. Sci. J. 2011, 82:406-411.
11. O'Keefe P.W., Wellington G.H., Mattick L.R., Stouffer J.R. Composition of bovine muscle lipids at various carcass locations. J. Food Sci. 1968, 33:188-192.
12. Roy R., Ordovas L., Zaragoza P., Romero A., Moreno C., Altarriba J., Rodellar C. Association of polymorphisms in the bovine FASN gene with milk-fat content. Anim. Genet. 2006, 37:215-218.
13. Schennink A., Bovenhuis H., Léon-Kloosterziel K.M., van Arendonk J.A., Visker M.H. Effect of polymorphisms in the FASN, OLR1, PPARGC1A, PRL and STAT5A genes on bovine milk-fat composition. Anim. Genet. 2009, 40:909-916.
14. Shouda Y. Holstein-Friesian. World Farm Animal Breed Encyclopedia (in Japanese), Toyo Shorin, Tokyo 2006, 53-55. Y. Shouda (Ed.).
15. Smith S. The animal fatty acid synthase: one gene, one polypeptide, seven enzymes. FASEB J. 1994, 8:1248-1259.
16. Soyeurt H., Gillon A., Vanderick S., Mayeres P., Bertozzi C., Gengler N. Estimation of heritability and genetic correlations for the major fatty acids in bovine milk. J. Dairy Sci. 2007, 90:4435-4442.
17. Stoop W.M., van Arendonk J.A., Heck J.M., van Valenberg H.J., Bovenhuis H. Genetic parameters for major milk fatty acids and milk production traits of Dutch Holstein Friesians. J. Dairy Sci. 2008, 91:385-394.
18. Vázquez M.J., Leavens W., Liu R., Rodríguez B., Read M., Richards S., Winegar D., Domínguez J.M. Discovery of GSK837149A, an inhibitor of human fatty acid synthase targeting the beta-ketoacyl reductase reaction. FEBS J. 2008, 275:1556-1567.
19. Zhang S., Knight J., Reecy J., Beitz D. DNA polymorphisms in bovine fatty acid synthase are associated with beef fatty acid composition. Anim. Genet. 2008, 39:62-70.