Fatty acid synthase effects on bovine adipose fat and milk fat

Mammalian Genome

Volumn 18, Issue 1, 2007, Pages 64-74

  Morris, Chris A ^a   Cullen, Neil G ^a   Glass, Belinda C ^b   Hyndman, Dianne L ^b   Manley, Tim R ^b   Hickey, Sharon M ^a   McEwan, John C ^b   Pitchford, Wayne S ^c   Bottema, Cynthia D K ^c   Lee, Michael A H ^b  

^a RUAKURA RESEARCH CENTRE   (New Zealand)

^b INVERMAY AGRICULTURAL CENTRE   (New Zealand)

^c UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

FATTY ACID SYNTHASE; MILK FAT;

ANIMAL TISSUE; ARTICLE; CHROMOSOMAL LOCALIZATION; CONTROLLED STUDY; COW; DAIRY CATTLE; FATTY ACID ANALYSIS; GENE AMPLIFICATION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENETIC ASSOCIATION; GENETIC DIFFERENCE; GENETIC LINKAGE; GENOTYPE; HAPLOTYPE; LIPID COMPOSITION; LIPID METABOLISM; MICROSATELLITE MARKER; NONHUMAN; NUCLEOTIDE SEQUENCE; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; SUBCUTANEOUS FAT; VALIDATION PROCESS;

ADIPOSE TISSUE; ANIMALS; BASE SEQUENCE; CATTLE; CHROMOSOME MAPPING; CROSSES, GENETIC; DNA PRIMERS; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS; FEMALE; HAPLOTYPES; LINKAGE DISEQUILIBRIUM; MALE; MILK; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI;

ANIMALIA; BOS; BOVINAE;

EID: 33846821372     PISSN: 09388990     EISSN: 14321777     Source Type: Journal    
DOI: 10.1007/s00335-006-0102-y     Document Type: Article

References (24)

1. Baumgard LH, Kay JK, Moore CE, Roche JR, Vanbaale MJ, et al. (2005) Regulating milk fat synthesis: potential on-farm applications of basic science. Proc NZ Soc Anim Prod 65, 33-39
2. Berner LA (1993) Defining the role of milkfat in balanced diets. Adv Food Nutr Res 37, 131-257
3. Clop A, Ovilo C, Perez-Enciso M, Cercos A, Tomas A, et al. (2003) Detection of QTL affecting fatty acid composition in the pig. Mamm Genome 14, 650-656
4. Davies HM (1996) Engineering new oilseed crops from rapeseed. In Progress in new crops. Proceedings of the Third National Symposium, Indianapolis, IN, 22-25 October 1996, Janick J, (ed). (Alexandria, VA: American Society for Horticultural Science Press), pp 299-306
5. Gaynor PJ, Waldo DR, Capuco AV, Erdman RA, Douglass LW, et al. (1995) Milk fat depression, the glucogenic theory, and trans-18:1 fatty acids. J Dairy Sci 78, 2008-2015
6. Goddard ME, Hayes B, McPartlan H, Chamberlain AJ (2006) Can the same genetic markers be used in multiple breeds? In Proceedings of the 8th World Congress on Genetics Applied to Livestock Production. Belo Horizonte, Brazil, August 2006 (CD-ROM summary)
7. Hansen H, Knudsen J (1987) Effect of exogenous long-chain fatty acids on individual fatty acid synthesis by dispersed ruminant mammary gland cells. J Dairy Sci 70, 1350-1354
8. Ihara N, Takasuga A, Mizoshita K, Takeda H, Sugimoto M, et al. (2004) A comprehensive genetic map of the cattle genome based on 3802 microsatellites. Genome Res 14, 1987-1998
9. Kappes SM, Keele JW, Stone RT, McGraw RA, Sonstegard TS, et al. (1997) A second-generation linkage map of the bovine genome. Genome Res 7, 235-249
10. Karamichou E, Richardson RI, Nute GR, Bishop SC (2006) Identification of quantitative trait loci affecting fatty acid composition in sheep. In Proceedings of the 8th World Congress on Genetics Applied to Livestock Production. Belo Horizonte, Brazil, August 2006, Conference Paper No. 13-12
11. Lee C, Chung Y, Kim J-H (2003) Quantitative trait loci mapping for fatty acid contents in the backfat on porcine chromosomes 1, 13, and 18. Molecules Cells 15, 62-67
12. Montgomery GW, Sise JA (1990) Extraction of DNA from sheep white blood cells. NZ J Agric Res 33, 437-441
13. Mozaffarian D, Ascherio A, Hu FB, Stampfer MJ, Willett WC, et al. (2005) Interplay between different polyunsaturated fatty acids and risk of coronary heart disease in men. Circulation 111, 157-164
14. Perez-Enciso M, Clop A, Noguera JL, Ovilo C, Coll A, et al. (2000) A QTL on pig chromosome 4 affects fatty acid metabolism: evidence from an Iberian by Landrace intercross. J Anim Sci 78, 2525-2531
15. Roy R, Gautier M, Hayes H, Laurent P, Osta R, et al. (2001) Assignment of the fatty acid synthase (FASN) gene to bovine chromosome 19 (19q22) by in situ hybridization and confirmation by somatic cell hybrid mapping. Cytogenet Cell Genet 93, 141-142
16. Roy R, Zaragoza P, Rodellar C, Gautier M, Eggen A (2005) Radiation hybrid and genetic linkage mapping of two genes related to fat metabolism in cattle: fatty acid synthase (FASN) and glycerol-3-phosphate acyltransferase mitochondrial (GPAM). Anim Biotechnol 161, 1-9
17. Roy R, Ordovas L, Zaragoza P, Romero A, Moreno C, et al. (2006) Association of polymorphisms in the bovine FASN gene with milk-fat content. Anim Genet 37, 215-218
18. SAS (1995) JMP v3 (Cary, NC: SAS Institute Inc.)
19. Seaton G, Haley CS, Knott SA, Kearsey M, Visscher PM (2002) QTL Express: mapping quantitative trait loci in simple and complex pedigrees. Bioinformatics 18, 339-340
20. Singh SP, Zhou XR, Liu Q, Stymne S, Green AG (2005) Metabolic engineering of new fatty acids in plants. Curr Opin Plant Biol 8, 197-203
21. Smith S (1994) The animal fatty acid synthase: one gene, one polypeptide, seven enzymes. FASEB J 8, 1248-1259
22. Spelman R, Coppieters W (2006) Linkage disequilibrium in the New Zealand Jersey population. In Proceedings of the 8th World Congress on Genetics Applied to Livestock Production. Belo Horizonte, Brazil, August 2006 (CD-ROM summary)
23. Taylor JF, Coutinho LL, Herring KL, Gallagher DS JR, Brenneman RA, et al. (1998) Candidate gene analysis of GH1 for effects on growth and carcass composition of cattle. Anim Genet 29, 194-201
24. Temme EH, Mensink RP, Hornstra G (1997) Effects of medium chain fatty acids (MCFA), myristic acid, and oleic acid on serum lipoproteins in healthy subjects. J Lipid Res 38, 1746-1754