Apo-8′-lycopenal induces expression of HO-1 and NQO-1 via the ERK/p38-Nrf2-ARE pathway in human HepG2 cells

Journal of Agricultural and Food Chemistry

Volumn 60, Issue 6, 2012, Pages 1576-1585

  Yang, Chih Min ^a   Huang, Shu Ming ^a   Liu, Cheng Ling ^a   Hu, Miao Lin ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION TIME; ANTIOXIDANT RESPONSE ELEMENTS; BINDING ACTIVITIES; CHEMOPREVENTIVE EFFECTS; CYTOSOLIC; HEME OXYGENASE-1; HEPG2 CELLS; HUMAN PLASMAS; LYCOPENES; NAD(P)H; NUCLEAR FACTORS; OXIDOREDUCTASES; PHASE II; RAT LIVERS; SPECIFIC INHIBITORS;

BIOMOLECULES; METABOLITES; PORPHYRINS;

METABOLISM;

RATTUS;

ANTINEOPLASTIC AGENT; ANTIOXIDANT; APO 10' LYCOPENOIC ACID; APO 8' LYCOPENAL; APO-10'-LYCOPENOIC ACID; APO-8'-LYCOPENAL; CAROTENOID; HEME OXYGENASE 1; LYCOPENE; NFE2L2 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRANSCRIPTION FACTOR NRF2; UNSATURATED FATTY ACID;

ARTICLE; CELL STRAIN HEPG2; DNA RESPONSIVE ELEMENT; DRUG EFFECT; GENE EXPRESSION; GENETICS; HUMAN; METABOLISM; SIGNAL TRANSDUCTION;

ANTICARCINOGENIC AGENTS; ANTIOXIDANTS; CAROTENOIDS; FATTY ACIDS, UNSATURATED; GENE EXPRESSION; HEME OXYGENASE-1; HEP G2 CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION;

EID: 84856905230     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf204451n     Document Type: Article

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