Apoptotic signaling in mouse odontogenesis

OMICS A Journal of Integrative Biology

Volumn 16, Issue 1-2, 2012, Pages 60-70

  Matalova, Eva ^a,b   Svandova, Eva ^a   Tucker, Abigail S ^c  

^a INSTITUTE OF ANIMAL PHYSIOLOGY AND GENETICS   (Czech Republic)

^b UNIVERSITY OF VETERINARY AND PHARMACEUTICAL SCIENCES   (Czech Republic)

^c KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; FAS ANTIGEN; FAS LIGAND; PROTEIN BCL 2;

AMELOBLAST; APOPTOSIS; CELL DEATH; CONFERENCE PAPER; ENZYME ACTIVITY; MINERALIZATION; MITOCHONDRION; MOUSE; NONHUMAN; ODONTOBLAST; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TOOTH; TOOTH DEVELOPMENT;

ANIMALS; APOPTOSIS; CASPASES; HUMANS; MICE; ODONTOGENESIS; SIGNAL TRANSDUCTION; TOOTH GERM;

EID: 84856882930     PISSN: 15362310     EISSN: 15578100     Source Type: Journal    
DOI: 10.1089/omi.2011.0039     Document Type: Conference Paper

References (127)

1. Ahn, Y., Sanderson, B.W., Klein, O.D., and Krumlauf, R. (2010). Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning. Development 127, 3221-3231.
2. Baratella, L., Arana-Chavez, V.E., and Katchburian, E. (1999). Apoptosis in the early involuting stellate reticulum of rat molar tooth germs. Anat. Embryol. 200, 49-54. (Pubitemid 29261625)
3. Bronckers, A.L., Lyaruu, D.M., Goei, W., Litz, M., Luo, G., Karsenty, G., et al. (1996). Nuclear DNA fragmentation during postnatal tooth development of mouse and hamster and during dentin repair in the rat. Eur. J.Oral. Sci. 104, 102-111.
4. Bronckers, A.L., Goei, S.W., Dumont, E., Lyaruu, D.M., Wöltgens, J.H., Van Heerde, W.L., et al. (2000). In situ detection of apoptosis in dental and periodontal tissues of the adult mouse using annexin-V-biotin. Histochem. Cell Biol. 113, 293-301. (Pubitemid 30256972)
5. Buchtova, M., Handrigan, G.R., Tucker, A.S., Scott, L., Town, L., Fu, K., et al. (2008). Initiation and patterning of the snake dental lamina are dependent on Sonic hedgehog signaling. Dev. Biol. 319, 132-145.
6. Catón, J., and Tucker, A.S. (2009). Current knowledge of tooth development: Patterning and mineralization of the murine dentition. J. Anat. 214, 502-515.
7. Cecconi, F., Alvarez-Bolado, G., Meyer, B.I., Roth, K.A., and Gruss, P. (1998). Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 94, 727-737. (Pubitemid 28436005)
8. Cerri, P.S., Freymuller, E., and Katchburian, E. (2000). Apoptosis in the early developing periodontium of rat molars. Anat. Rec. 258, 136-144. (Pubitemid 30082906)
9. Chlastakova, I., Lungova, V., Wells, K., Tucker, A.S., Radlanski, R.J., Misek, I., et al. (2011). Morphogenesis and bone integration of the mouse mandibular third molar. Eur. J. Oral Sci. 119, 265-273.
10. Cho, S.W., Lee, H.A., Cai, J.L., Lee, M.J., Kim, J.Y., Ohshima, H., et al. (2007). The primary enamel knot determines the position of the first buccal cusp in developing mice molars. Differentiation 75, 441-451. (Pubitemid 46802157)
11. Cobourne, M.T., and Sharpe, P.T. (2003). Tooth and jaw: Molecular mechanisms of patterning in the first branchial arch. Arch. Oral Biol. 48, 1-14. (Pubitemid 36453323)
12. Cobourne, M.T., and Sharpe, P.T. (2005). Sonic hedgehog signaling and the developing tooth. Curr. Top. Dev. Biol. 65, 255-287.
13. Cobourne, M.T., and Sharpe, P.T. (2010). Making up the numbers: The molecular control of mammalian dental formula. Semin. Cell. Dev. Biol. 21, 314-324.
14. Cobourne, M.T., Hardcastle, Z., and Sharpe, P.T. (2001). Sonic hedgehog regulates epithelial proliferation and cell survival in the developing tooth germ. J. Dent. Res. 80, 1974-1979.
15. Cohen, G.M., Sun, X.M., Fearnhead, H., Macfarlane, M., Brown, D.G., Snowden, R.T., et al. (1994). Formation of large molecular weight fragments of DNA is a key committed step of apoptosis in thymocytes. J. Immunol. 153, 507-516. (Pubitemid 24206280)
16. Coin, R., Kieffer, S., Lesot, H., Vonesch, J.L., and Ruch, J.V. (2000). Inhibition of apoptosis in the primary enamel knot does not affect specific tooth crown morphogenesis in the mouse. Int. J. Dev. Biol. 44, 389-396. (Pubitemid 30624793)
17. Cui, R.T., Nguyen, T.T., Taube, J.H., Stratton, S.A., Feuerman, M.H., and Barton, M.C. (2005). Family members p53 and p73 act together in chromatin modification and direct repression of alpha-fetoprotein transcription. J. Biol. Chem. 280, 39152-39160. (Pubitemid 41713866)
18. Deng, C., Zhang, P., Harper, J.W., Elledge, S.J., and Leder, P. (1995). Mice lacking p21 cIP11/WAf undergo normal development, but are defective in G1 checkpoint control. Cell 82, 675-684.
19. Deveraux, Q.L., and Reed, J.C. (1999). IAP family proteins- suppressors of apoptosis. Genes Dev. 13, 239-252. (Pubitemid 29095796)
20. Diep, L., Matalova, E., Mitsiadis, T.A., and Tucker, A.S. (2009). Contribution of the tooth bud mesenchyme to alveolar bone. J. Exp. Zool. Part B Mol. Dev. Evol. 312B, 510-517.
21. Donehower, L.A., Harvey, M., Slagle, B.L., McArthur, M.J., Montgomery, C.A., Butel, J.S., et al. (1992). Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours. Nature 356, 215-221.
22. Doseff, A.I. (2004). Apoptosis: The sculptor of development. Stem Cells Dev. 13, 473-483. (Pubitemid 39473578)
23. Du, C., Fang, M., Li, Y., Li, L., and Wang, X. (2000). Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102, 33-42.
24. Ekert, P.G., Silke, J., Hawkins, C.J., Verhagen, A.M., and Vaux, D.L. (2001). DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9. J. Cell Biol. 152, 483-490. (Pubitemid 34280232)
25. Elliot, J., Scarpello, J.H., and Morgan, N.G. (2001). Effects of tyrosine kinase inhibitors on cell death induced by sodium fluoride and pertusis toxin in the pancreatic beta-cell line, R1Nm5F. Br. J. Pharmacol. 132, 119-126. (Pubitemid 32128440)
26. Fleischmannova, J., Matalova, E., Tucker, A.S., and Sharpe, P.T. (2008). Mouse models of tooth abnormalities. Eur. J. Oral Sci. 116, 1-10.
27. Fleischmannova, J., Matalova, E., Sharpe, P.T., Misek, I., and Radlanski, R.J. (2010). Formation of the tooth-bone interface. J. Dent. Res. 89, 108-115.
28. French, L.E., Hahne,M., and Viard, I. (1996). Fas and Fas Ligand in embryos and adult mice: Ligand expression in several immuneprivileged tissues and co-expression in adult tissues characterized by apoptotic cell turnover. J. Cell Biol. 133, 335-343. (Pubitemid 26132532)
29. Goga, Y., Chiba, M., Shimizu, Y., and Mitani, H. (2006). Compressive force induces osteoblast apoptosis via caspase-8. J. Dent. Res. 85, 240-244. (Pubitemid 43827732)
30. Goldberg, M., Lasfargues, J.J., and Legrand, J.M. (1994). Clinical testing of dental materials-histological considerations. J. Dent. 22, 25-28.
31. Golpon, H.A., Fadok,V.A.,Taraseviciene-Stewart, L., Scerbavicius, R., Sauer, C., Welte, et al. (2004). Life after corpse engulfment: Phagocytosis of apoptotic cells leads to VEGF secretion and cell growth. FASEB J. 18, 1716-1718. (Pubitemid 39561661)
32. Govorko, D.K., Becic, T., Vukojevic, K., Mardesic-Brakus, S., Biocina-Lukenda, D., and Saraga-Babic, M. (2010). Spatial and temporal distribution of Ki-67 proliferation marker, Bcl-2 and Bax proteins in the developing human tooth. Arch. Oral Biol. 55, 1007-1016.
33. Handrigan, G.R., and Richman, J.M. (2010). Autocrine and paracrine Shh signaling are necessary for tooth morphogenesis, but not tooth replacement in snake and lizards (Squamata). Dev. Biol. 337, 171-186.
34. Hatakeyama, S., Tomichi, N., Ohara-Nemoto, Y., and Satoh, M. (2000). The immunohistochemical localistaion of Fas and Fas ligand in jaw bone and tooth germ of human fetuses. Calcif. Tissue Int. 66, 330-337. (Pubitemid 30225392)
35. Headon, D.J., Emmal, S.A., Ferguson, B.M., Tucker, A.S., Justice, M.J., Sharpe, P.T., et al. (2001). Gene defect in ectodermal dysplasia implicates a death domain adapter in development. Nature 414, 913-916. (Pubitemid 34024742)
36. Hengartner, M.O. (2000). The biochemistry of apoptosis. Nature 407, 770-776.
37. Hughes, D.E., and Boyce, B.F. (1997). Apoptosis in bone physiology and disease. Mol. Pathol. 50, 132-137. (Pubitemid 27454997)
38. Irmler, M., Thome, M., Hahne, M., Schneider, P., Hofmann, K., Steiner, V., et al. (1997). Inhibition of death receptor signals by cellular FLIP. Nature 388, 190-195. (Pubitemid 27297457)
39. Jacinto-Alema, L.F., Hernandez-Guerrero, J.C., Trejo-Solis, C., Jimenez-Farfan, M.D., and Fernández-Presas, A.M. (2010). In vitro effect of sodium fluoride on antioxidative enzymes and apoptosis during murine odontogenesis. J. Oral Pathol. Med. 39, 709-714.
40. Jernvall, J., and Thesleff, I. (2000). Reiterative signaling and patterning during mammalian tooth morphogenesis. Mech. Dev. 92, 19-29. (Pubitemid 30125959)
41. Jernvall, J., Åberg, T., Kettunen, P., Keranen,S., and Thesleff, I. (1998). The life history of an embryonic signalling center: BMP-4 induces p-21 and is associated with apoptosis in the mouse tooth enamel knot. Development 125, 161-169. (Pubitemid 28064430)
42. Jernvall, J., Keranen, S.V.E., and Thesleff, I. (2000). Evolutionary modification of development in mammalian teeth: Quantifying gene expression patterns and topography. Proc. Natl. Acad. Sci. USA 97, 14444-14448. (Pubitemid 32016595)
43. Kere, J., Srivasta, A.K., Montonen, O., Zonana, J., Thomas, N., Ferguson, B., et al. (1996). X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by a mutation in a novel transmembrane protein. Nat. Genet. 13, 409-416. (Pubitemid 26256613)
44. Kerr, J.F., Wyllie, A.H., and Currie, A.R. (1972). Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 26, 239-257.
45. Kieffer, S., Peterková , R., Vonesch, J.L., Ruch, J.V., Peterka, M., and Lesot, H. (1999). Morphogenesis of the lower incisor in the mouse from the bud to early bell stage. Int. J. Dev. Biol. 43, 531-539.
46. Kim, J.Y., Cha, Y.G., Cho, S.W., Kim, E.J., Lee, M.J., Lee, J.M., et al. (2006). Inhibition of apoptosis in early tooth development alters tooth shape and size. J. Dent. Res. 85, 530-535.
47. Kitamura, C., Kimura, K., Nakayama, T., Toyoshima, K., and Terashita, M. (2001). Primary and secondary induction of apoptosis in odontoblasts after cavity preparation of rat molars. J. Dent. Res. 80, 1530-1534.
48. Kobayashi, Y., Hashimoto, F., Miyamoto, H., Kanaoka, K., Miyazaki-Kawashita, Y., Nakashima, T., et al. (2000). Forceinduced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression. J. Bone Miner. Res. 15, 1924-1934.
49. Kondo, S., Tamura, Y., Bawden, J.W., and Tanase, S. (2001). The immunohistochemical localization of Bax and Bcl-2 and their relation to apoptosis during amelogenesis in developing rat molars. Arch. Oral Biol. 46, 557-568. (Pubitemid 32476086)
50. Kuida, K., Zheng, T.S., Na, S., Kuan, C., Yang, C.D., Karasumaya, H., et al. (1996). Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 384, 368-372. (Pubitemid 26408520)
51. Kuida, K., Haydar, T.F., Kuan, C.Y., Gu, Y., Taya, C., Karasuyama, H., et al. (1998). Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 94, 325-337. (Pubitemid 28376077)
52. Kuranaga, E. (2011). Caspase signaling in animal development. Dev. Growth Diff. 53, 137-148.
53. Lacasse, E.C., Baird, S., Korneluk, R.G., and Mackenzie, A.E. (1998). The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 17, 3247-3259. (Pubitemid 29043977)
54. Lamkanfi, M., Kanneganti, T.D., Franchi, L., and Núńez, G. (2007). Caspase-1 inflammasomes in infection and inflammation. J. Leukoc. Biol. 82, 1-6.
55. Lavrik, I.N., Golks, A., and Krammer, P.H. (2005). Caspases: Pharmacological manipulation of cell death. J. Clin. Invest. 115, 2665-2672. (Pubitemid 41434390)
56. Lechguer, N.A., Kuchler-Bopp, S., Hu, B., Haïkel, Y., and Lesot, H. (2008). Vascularization of engineered teeth. J. Dent. Res. 87, 1138-1143.
57. Lesot, H., Vonesch, J.L., Peterka, M., Turecková , J., Peterková , R., and Ruch, J.V. (1996). Mouse molar morphogenesis revisited by threedimensional reconstruction. II. Spatial distribution of mitoses and apoptosis in cap to bell staged first and second upper molar teeth. Int. J. Dev. Biol. 40, 1017-1031. (Pubitemid 26387223)
58. Li, L., Yuan, G., Liu, C., Zhang, L., Zhang, Y., Chen, Y., et al. (2011). Exogenous fibroblast growth factor 8 rescues development of mouse diastemal vestigal tooth ex vivo. Dev. Dyn. online March 15.
59. Lungová , V., Radlanski, R.J., Tucker, A.S., Renz, H., Míšek, I., and Matalová , E. (2011). Tooth-bone morphogenesis during postnatal stages of mouse first molar development. J. Anat. 218, 699-715.
60. Luukko, K., Loes, S., Furmanek, T., Fjeld, K.,Kvinnsland, I.H., and Kettunen, P. (2003). Identification of a novel putative signaling center, the tertiary enamel knot in the postnatal mouse molar tooth. Mech. Dev. 120, 270-276. (Pubitemid 36184622)
61. Martin, S.J., and Green, D.R. (1995). Protease activation during apoptosis: Death by a thousand cutš Cell 82, 349-352.
62. Martin, S.J., Reutelingsperger, C.P., McGahon, A.J., Rader, J.A., Van Schie, R.C., Laface, D.M., et al. (1995). Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl. J. Exp. Med. 182, 1545-1556.
63. Martins, C.A., Rivero, E.R.C., Dufloth, R.M., Figueiredo, C.P., and Vieira, D.S.C. (2011). Immunohistochemical detection of factors related to cellular proliferation and apoptosis in radicular and dentigerous cysts. J. Endod. 37, 36-39.
64. Matalova, E., Tucker, and Sharpe, P.T. (2004). Death in the life of a tooth. J. Dent. Res. 83, 11-16. (Pubitemid 41756851)
65. Matalova, E., Tucker, A.S., and Misek, I. (2005). Apoptosis-related factors (Fas receptor, Fas ligand, FADD) in early tooth development of the field vole (Microtus agrestis). Arch. Oral Biol. 50, 165-169. (Pubitemid 40252934)
66. Matalova, E., Sharpe, P.T., Lakhani, S.A., Roth, K.A., Flavell, R.A., Setkova, J., et al., (2006). Molar tooth development in caspase-3 deficient mice. Int. J. Dev. Biol. 50, 491-497. (Pubitemid 43844798)
67. Matalova, E., Dubska, L., Fleischmannova, J., Chlastakova I., Janeckova, E., and Tucker, A.S. (2010). Cell proliferation and apoptosis in the primary enamel knot measured by flow cytometry of laser microdissected symplex. Arch. Oral Biol. 55, 570-575.
68. Meier, P., Finch, A., and Evan, G. (2000). Apoptosis in development. Nature 407, 796-801.
69. Mikkola, M.L. (2007). p63 in skin appendage development. Cell Cycle 6, 285-290.
70. Mills, A.A., Zheng, B., Wang, X.J., Vogel, H., Roop, D.R., and Bradley, A. (1999). p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 398, 708-713. (Pubitemid 29197649)
71. Mitsiadis, T.A., Couble, P., Dicou, E., Rudkin, B.B., and Magloire, H. (1993). Patterns of nerve growth factor (NGF) proNGF, and p75, NGF receptor expression in the rat incisor: Comparison with expression in the molar. Differentiation 54, 161-175. (Pubitemid 23352261)
72. Mitsiadis, T.A., De Bari, C., and About, I. (2008). Apoptosis in developmental and repair-related human tooth remodeling: A view from the inside. Exp. Cell Res. 314, 869-877. (Pubitemid 351191905)
73. Monteiro, J., Day, P., Duggal, M., and Morgan C. (2009). Pulpal status of human primary teeth with physiological root resorption. Int. J. Paediatr. Dent. 19, 16-25.
74. Montero, J.A., and Hurle, J.M.(2010). Sculpturing digit shape by cell death. Apoptosis 15, 365-375.
75. Montero, J.A., Macias, D., Ganan, Y., Merino, R., Chimal-Monroy, J., and Hurle, J.M. (2001). Interactions between FGFs and BMPs in the control of programmed cell death in the developing limb. Int. J. Dev. Biol. 45, S113-S114. (Pubitemid 32843351)
76. Moriguchi, M., Yamada, M., Miake, Y., and Yanagisawa, T. (2010). Transforming growth factor beta inducible apoptotic cascade in epithelial cells during rat molar tooth eruptions. Anat. Sci. Int. 85, 92-101.
77. Munne, P.M., Tummers, M., Jarvinen, E., Thesleff, I., and Jernvall, J. (2009). Tinkering with the inductive mesenchyme: Sostdc1 uncovers the role of dental mesecnhyme in limiting tooth number. Development 136, 393-402.
78. Nicholson, D.W. (1999). Caspase structure, proteolytic substrates, and function during apoptotic cell death. Cell Death Diff. 6, 1028-1042.
79. Nishikawa, S., and Sasaki, F. (1999). Apoptosis of dental pulp cells and their elimination by macrophages and MHC class IIexpressing dendritic cells. J. Histochem. Cytochem. 47, 303-312.
80. Ohazama, A., and Sharpe, P.T. (2004). TNF signalling in tooth development. Curr. Opin. Genet. Dev. 14, 513-519. (Pubitemid 39360298)
81. Ohazama, A., Haycraft, C.J., Seppala, M., Blackburn, J., Ghafoor, S., Cobourne, M., et al. (2009). Primary cilia regulate Shh activity in the control of molar tooth number. Development 136, 897-903.
82. Peterkova, R., Peterka, M., Vonesch, J.L., and Ruch, J.V. (1993). Multiple developmental origin of the upper incisor in mouse: Histological and computer assisted 3D reconstruction. Int. J. Dev. Biol. 37, 581-588. (Pubitemid 24063760)
83. Peterkova, R., Peterka, M., Vonesch, J.L., Tureckova, J., Viriot, L., Ruch, J.V., et al. (1998). Correlation between apoptosis distribution and BMP-2 and BMP-4 expression in vestigial tooth primordia in mice. Eur. J. Oral Sc. 106, 667-670. (Pubitemid 128737073)
84. Peterkova, R., Peterka, M., Viriot, L., and Lesot, H. (2000). Dentition development and budding morphogenesis. J. Craniofac. Genet. Dev. Biol. 20, 158-172. (Pubitemid 32336895)
85. Peterková , R., Peterka, L., Viriot, L., and Lessot, H. (2002). Development of the vestigial tooth primordia as a part of mouse odontogenesis. Connect. Tissue Res. 43,120-128. (Pubitemid 34777912)
86. Peterková , R., Peterka, M., and Lesot, H. (2003). The developing mouse dentition: A new tool for apoptosis study. Ann. N. Y. Acad. Sci. 1010, 453-466. (Pubitemid 38265025)
87. Peterkova, R., Churava, S., Lesot, H., Rothova, M., Prochazka, J., Peterka, M., et al. (2009). Revitalization of a diastemal tooth primordium in Spry2 null mice results from increased proliferation and decreased apoptosis. J. Exp. Zool. Part B Mol. Dev. Evol. 312B, 292-308.
88. Piattelli, A., Rubini, C., Fioroni, M., Ciavarelli, L., and De Fazio, P. (2000). Bcl-2, p53, and MIB-1 in human adult dental pulp. J. Endod. 26, 225-227.
89. Pouliot, F., and Labrie, C. (2002). Role of Smad1 and Smad4 in the induction of p21WAF1, Cip1 during bone morphogenetic protein-induced growth arrest in human breast cancer cells. J. Endocrinol. 72, 187-198 (Pubitemid 34082957)
90. Prochazka, J., Pantalacci, S., Churava, S., Rothova, M., Lambert, A., Lesot, H., et al. (2010). Patterning by heritage in mouse molar row development. Proc. Natl. Acad. Sci. USA 107, 15497-15502.
91. Pycroft, J.M., Hann, A., and Moxham, B.J. (2002). Apoptosis in the connective tissues of the periodontal ligament and gingivae of rat incisor and molar teeth at various stages of development. Connect. Tissue Res. 43, 265-279. (Pubitemid 34777935)
92. Ranger, A.M., Malynn, B.A., and Kosmeyer, S.J. (2001). Mouse model of cell death. Nat. Genet. 28, 113-118.
93. Ray, C.A., Black, R.A., Kronheim, S.R., Greenstreet, T.A., Sleath, P.R., Salvesen, G.S., et al. (1992) Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1 beta converting enzyme. Cell 69, 597-604.
94. Riedl, S.J., Renatus, M., Schwarzenbacher, R., Zhou, Q., Sun, C., Fesik, S.W. et al., (2001). Structural basis for the inhibition of caspase-3 by XIAP. Cell 104, 791-800. (Pubitemid 32241028)
95. Robinson, C., Connell, S., Kirkham, J., Brookes, S.J., Shore, R.C., and Smith, A.M. (2004). The effect of fluoride on the developing tooth. Caries Res. 38, 268-276. (Pubitemid 38720224)
96. Satchell, P.G., Gutmann, J.L., and Witherspoon, D.E. (2003) Apoptosis: An introduction for the endodontist. Int. Endod. J. 36, 237-245. (Pubitemid 37255727)
97. Savill, J., and Fadok, V. (2000). Corpse clearance defines the meaning of cell death. Nature 407, 784-788.
98. Savill, J., Fadok, V., Henson, P., and Haslety, C. (1993). Phagocytic recognition of cells undergoing apoptosis. Immunol. Today 14, 131-136. (Pubitemid 23068298)
99. Setkova, J., Lesot, H., Matalova, E., Witter, K., Matulova, P., and Misek, I. (2006). Proliferation and apoptosis in early molar morphogenesis-voles as models in odontogenesis. Int. J. Dev. Biol. 50, 481-489. (Pubitemid 43844797)
100. Setkova, J., Matalova, E., Sharpe, P.T., Misek, I., and Tucker, A. (2007). Primary enamel knot cell death in Apaf-1 and caspase- 9 deficient mice. Arch. Oral Biol. 52, 15-19. (Pubitemid 44872874)
101. Shi, Y. (2002). Mechanisms of caspase activation and inhibition during apoptosis. Mol. Cell 9, 459-470. (Pubitemid 34273778)
102. Shigemura, N., Kiyoshima, T., Sakai, T., Matsuo, K., Momoi, T., Yamaza, H., et al. (2001). Localization of activated caspase-3- positive and apoptotic cells in the developing tooth germ of the mouse lower forst molar. Histochem. J. 33, 253-258. (Pubitemid 32807973)
103. Slootweg, P.J, and de Weger, R.A. (1994). Immunohistochemical demonstration of bcl-2 protein in human tooth germs. Arch. Oral Biol. 39, 545-550.
104. Smith, C.E. (1998). Cellular and chemical events during enamel maturation. Crit. Rev. Oral Biol. Med. 9, 128-161. (Pubitemid 28225853)
105. Suliman, A., Lam, A., Datta, R., and Srivastava, R.K. (2001). Intracellular mechanism of TRAIL: Apoptosis through mitochondrial- dependent and -independent pathways. Oncogene 20, 2122-2133. (Pubitemid 32424006)
106. Sun, C., Cai, M., Gunasekera, A.H., Meadows, R.P., Wang, H., Chen, J., et al., (1999). NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP. Nature 401, 818-821.
107. Szymczyk, K.H., Freeman, T.A., Adams, C.S., Srinivas, V., and Steinbeck, M.J. (2006). Active caspase-3 is required for osteoclast differentiation. J. Cell. Physiol. 209, 836-844. (Pubitemid 44665705)
108. Takahashi, R., Deveraux, Q., Tamm, I., Welsh, K., Assamunt, N., Salvesen, G.S., et al., (1998). A single bir domain of xiap sufficient for inhibiting caspases. J. Biol. Chem. 273, 7787-7790. (Pubitemid 28168819)
109. Ten Cate, A.R. (1998). Dentinogenesis. In: Oral Histology: Development, Structure, and Function, 5th ed. pp. 128-149. A.R. Ten Cate, ed. (CV Mosby, St. Louis, MO).
110. Tsuchiya, M., Sharma, R., Tye, C.E., Sugiyama, T., and Bartlett, J.D. (2009). Transforming growth factor-b1 expression is upregulated in maturation-stage enamel organ and may induce ameloblast apoptosis. Eur. J. Oral Sci. 117, 105-112.
111. Tucker, A.S., and Sharpe, P.T. (1999). Molecular genetics of tooth morphogenesis and patterning, the right shape in the right place. J. Dent. Res. 78, 826-834. (Pubitemid 32489301)
112. Tucker, A., and Sharpe, P. (2004). The cutting-edge of mammalian development; how the embryo makes teeth. Nat. Rev. Genet. 5, 499-508. (Pubitemid 38868506)
113. Tucker, A.S., Headon, D.J., Schneider, P., Ferguson, B.M., Overbeek, P., Tschopp, J., et al. (2000). Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis. Development 127, 4691-4700.
114. Tureckova, J., Lesot, H., Vonesh, J.L., Peterka, M., Peterková , R., and Ruch, J.V. (1996). Apoptosis is involved in disapearance of the diastemal dental primordia in mouse embryo. Int. J. Dev. Biol. 40, 483-489. (Pubitemid 26187830)
115. Vaahtokari, A., Åberg, T., and Thesleff, I. (1996). Apoptosis in developing tooth: Association with an embryonic signalling center and suppression of EGF and FGF-4. Development 122, 121-129. (Pubitemid 26038424)
116. Varfolomeev, E.E., Schuchmann, M., Luria, V., Chiannilkulchai, N.,Beckmann, J.S., Mett, I.L., et al. (1998). Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1 and DR3 and is lethal prenatally. Immunity 9, 267-276. (Pubitemid 28400040)
117. Verhagen, A.M., Ekert, P.G., Pakusch, M., Silke, J., Connolly, L.M., Reid, G.E., et al. (2000). Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. Cell 102, 43-53.
118. Watanabe-Fukunaga, R., Brannan, C.I., Itoh, N., Yonehara, S., Copeland, N.G., Jenkins, N. A., et al. (1992). The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. J. Immunol. 148, 1274-1279.
119. Wood, D.E., and Newcomb, E.W. (2000). Cleavage of Bax enhances its cell death function. Exp. Cell Res. 256, 375-382. (Pubitemid 30244196)
120. Yoshioka, C., Muraki, Y., Fukuda, J., Haneji, T., and Kobayashi, N. (1996). Identification of the Fas antigen in human gingiva. J. Dent. Res. 75,1353-1357. (Pubitemid 32774103)
121. Zahradnicek, O., Horacek, I., and Tucker, A.S. (2008) Viperous fangs: Molecular evidence for the infolding theory of venomcanal development. Mech. Dev. 125, 786-796.
122. Zakeri, Z., Lockshin, R.A., Criado-Rodrigues, L.M., Martinez, A.C. (2005). A generalized caspase inhibitor disrupts early mammalian development. Int J. Dev. Biol. 49, 43-47. (Pubitemid 40516367)
123. Zhang, W., Ju, J., and Gronowicz, G. (2010). Odontoblast-targeted Bcl-2 overexpression impairs dentin formation. J. Cell. Biochem. 111, 425-432.
124. Zheng, T.S., Hunot, S., Kuida, K., and Flavell, R.A. (1999). Caspase knockouts: Matters of life and death. Cell Death Diff. 6, 1043-1053.
125. Zheng, X.M., Resnick, R.J., and Shalloway, D. (2000). A phosphotyrosine displacement mechanism for activation of Src by PTP . EMBO J. 19, 964-978. (Pubitemid 30119822)
126. Zimmermann, K.C., Bonzon, C., and Green, D.R. (2001). The machinery of programmed cell death. Pharmacol. Ther. 92, 57-70. (Pubitemid 34032022)
127. Zou, H., Henzel, W.J., Liu, X., Lutschg, A., and Wang, X. (1997). Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase- 3. Cell 90, 405-413. (Pubitemid 27347231)