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Volumn 5, Issue 1, 2011, Pages 1-17

Individualization of antiretroviral therapy

Author keywords

Antiretroviral; HIV; Personalized medicine; Pharmacogenetics; Pharmacogenomics

Indexed keywords

ABACAVIR; ABACAVIR PLUS LAMIVUDINE; ANTIRETROVIRUS AGENT; ATAZANAVIR PLUS RITONAVIR; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; DARUNAVIR PLUS RITONAVIR; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; FOSAMPRENAVIR PLUS RITONAVIR; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 2B7; GLYCOPROTEIN P; HLA B ANTIGEN; HLA DRB1 ANTIGEN; LAMIVUDINE; LAMIVUDINE PLUS ZIDOVUDINE; LOPINAVIR PLUS RITONAVIR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MARAVIROC; MULTIDRUG RESISTANCE PROTEIN 1; NEVIRAPINE; ORGANIC ANION TRANSPORTER 1; RALTEGRAVIR; SAQUINAVIR; UNINDEXED DRUG;

EID: 84856809606     PISSN: None     EISSN: 11787066     Source Type: Journal    
DOI: 10.2147/PGPM.S15303     Document Type: Review
Times cited : (28)

References (154)
  • 1
    • 84855616052 scopus 로고    scopus 로고
    • Panel on Antiretroviral Guidelines for Adults and Adolescents, Department of Health and Human Services, Available from, Accessed September 4, 2011
    • Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. 2011:1-66. Available from: http://www.aidsinfo.nih.gov/ContentFiles/Adultand-AdolescentGL.pdf. Accessed September 4, 2011.
    • (2011) Guidelines For the Use of Antiretroviral Agents In HIV-1-infected Adults and Adolescents , pp. 1-66
  • 2
    • 77954692660 scopus 로고    scopus 로고
    • Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society-USA panel
    • Thompson M, Aberg J, Cahn P, et al. Antiretroviral treatment of adult HIV infection: 2010 recommendations of the International AIDS Society-USA panel. JAMA. 2010;304(3):321-333.
    • (2010) JAMA , vol.304 , Issue.3 , pp. 321-333
    • Thompson, M.1    Aberg, J.2    Cahn, P.3
  • 3
    • 78649382207 scopus 로고    scopus 로고
    • European AIDS Clinical Society Guidelines, Version 5-4, Available from, Accessed October 17, 2011
    • European AIDS Clinical Society Guidelines. Clinical Management and treatment of HIV-infected Adults in Europe. Version 5-4 2009. Available from: www.eacs.eu. Accessed October 17, 2011.
    • (2009) Clinical Management and Treatment of HIV-infected Adults In Europe
  • 4
    • 34447299614 scopus 로고    scopus 로고
    • World Health Organization, Recommendations for a public health approach: 2010 Revision. Available from, Accessed October 17, 2011
    • World Health Organization. Antiretroviral therapy for HIV infection in adults and adolescents. Recommendations for a public health approach: 2010 Revision. Available from: http://www.who.int/hiv/pub/arv/adult2010/en/index.html. Accessed October 17, 2011.
    • Antiretroviral Therapy For HIV Infection In Adults and Adolescents
  • 5
    • 77954746096 scopus 로고    scopus 로고
    • Improved detection of CXCR4- using HIV by V3 genotyping: Application of population based and "deep" sequencing to plasma RNA and proviral DNA
    • Swenson MC, Moores A, Low AJ, et al. Improved detection of CXCR4- using HIV by V3 genotyping: application of population based and "deep" sequencing to plasma RNA and proviral DNA. J Acquir Immune Defic Syndr. 2010;54(5):506-510.
    • (2010) J Acquir Immune Defic Syndr , vol.54 , Issue.5 , pp. 506-510
    • Swenson, M.C.1    Moores, A.2    Low, A.J.3
  • 7
    • 68049110629 scopus 로고    scopus 로고
    • Personalizing antiretroviral therapy: Is it a reality?
    • Phillips E, Mallal S. Personalizing antiretroviral therapy: is it a reality? Personalized Medicine. 2009;6(4):393-408.
    • (2009) Personalized Medicine , vol.6 , Issue.4 , pp. 393-408
    • Phillips, E.1    Mallal, S.2
  • 8
    • 0037006623 scopus 로고    scopus 로고
    • Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
    • Mallal S, Nolan D, Witt C, et al. Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet. 2002;359(9308): 727-732.
    • (2002) Lancet , vol.359 , Issue.9308 , pp. 727-732
    • Mallal, S.1    Nolan, D.2    Witt, C.3
  • 9
    • 0037197044 scopus 로고    scopus 로고
    • Genetic variation in HLA-B region and hypersensitivity reactions to abacavir
    • Hetherington S, Hughes AR, Mosteller M, et al. Genetic variation in HLA-B region and hypersensitivity reactions to abacavir. Lancet. 2002;359(9312):1121-1122.
    • (2002) Lancet , vol.359 , Issue.9312 , pp. 1121-1122
    • Hetherington, S.1    Hughes, A.R.2    Mosteller, M.3
  • 10
    • 64349088125 scopus 로고    scopus 로고
    • Successful translation of pharmacogenetics into the clinic: The abacavir example
    • Phillips E, Mallal S. Successful translation of pharmacogenetics into the clinic: the abacavir example. Mol Diagn Ther. 2009;13(1):1-9.
    • (2009) Mol Diagn Ther , vol.13 , Issue.1 , pp. 1-9
    • Phillips, E.1    Mallal, S.2
  • 11
    • 77957282498 scopus 로고    scopus 로고
    • The convergence of therapeutic drug monitoring and pharmacogenetic testing to optimize efavirenz therapy
    • Figueroa SC, de Gatta MF, Garcia LH, et al. The convergence of therapeutic drug monitoring and pharmacogenetic testing to optimize efavirenz therapy. Ther Drug Monit. 2010;32(5):579-585.
    • (2010) Ther Drug Monit , vol.32 , Issue.5 , pp. 579-585
    • Figueroa, S.C.1    de Gatta, M.F.2    Garcia, L.H.3
  • 12
    • 0035875828 scopus 로고    scopus 로고
    • Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1 infected patients
    • Marzolini C, Telenti A, Decosterd LA, Greub G, Bioliaz J, Buclin T. Efavirenz plasma levels can predict treatment failure and central nervous system side effects in HIV-1 infected patients. AIDS. 2001;15(1):71-75.
    • (2001) AIDS , vol.15 , Issue.1 , pp. 71-75
    • Marzolini, C.1    Telenti, A.2    Decosterd, L.A.3    Greub, G.4    Bioliaz, J.5    Buclin, T.6
  • 13
    • 67349205036 scopus 로고    scopus 로고
    • Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1 infected individuals
    • Arab-alameddine M, Di Iulio J, Buclin T, et al. Pharmacogenetics-based population pharmacokinetic analysis of efavirenz in HIV-1 infected individuals. Clin Pharmcol Ther. 2009;85(5):485-494.
    • (2009) Clin Pharmcol Ther , vol.85 , Issue.5 , pp. 485-494
    • Arab-Alameddine, M.1    di Iulio, J.2    Buclin, T.3
  • 14
    • 63849240305 scopus 로고    scopus 로고
    • In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function
    • Di Iulio J, Fayet A, Arab-Alameddine M, et al. In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function. Pharmacogen Genomics. 2009;19(4):300-309.
    • (2009) Pharmacogen Genomics , vol.19 , Issue.4 , pp. 300-309
    • di Iulio, J.1    Fayet, A.2    Arab-Alameddine, M.3
  • 15
    • 63849281439 scopus 로고    scopus 로고
    • CYP2B6(c.516 G--.T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients
    • Kwara A, Lartey M, Sagoe KW, Rzek NL, Court MH. CYP2B6(c.516 G--.T) and CYP2A6 (*9B and/or *17) polymorphisms are independent predictors of efavirenz plasma concentrations in HIV-infected patients. Br J Clin Pharmacol. 2009;67(4):427-436.
    • (2009) Br J Clin Pharmacol , vol.67 , Issue.4 , pp. 427-436
    • Kwara, A.1    Lartey, M.2    Sagoe, K.W.3    Rzek, N.L.4    Court, M.H.5
  • 16
    • 77952322356 scopus 로고    scopus 로고
    • CYP2B6, CYP2A6 and UGT2B7 polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients
    • Kwara A, Lartey M, Sagoe KW, Kenu E, Court MH. CYP2B6, CYP2A6 and UGT2B7 polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients. AIDS. 2009;23(16):2101-2106.
    • (2009) AIDS , vol.23 , Issue.16 , pp. 2101-2106
    • Kwara, A.1    Lartey, M.2    Sagoe, K.W.3    Kenu, E.4    Court, M.H.5
  • 17
    • 77953756056 scopus 로고    scopus 로고
    • Efavirenz primary and secondary metabolism in vitro and in vivo: Identification of novel metabolic pathways and cytochrome P450 2A6 as the principal catalyst of efavirenz 7-hydroxylaiton
    • Ogburn ET, Jones DR, Masters AR, Xu C, Guo Y, Desta Z. Efavirenz primary and secondary metabolism in vitro and in vivo: identification of novel metabolic pathways and cytochrome P450 2A6 as the principal catalyst of efavirenz 7-hydroxylaiton. Drug Metab Dispos. 2010;38(7):1218-1229.
    • (2010) Drug Metab Dispos , vol.38 , Issue.7 , pp. 1218-1229
    • Ogburn, E.T.1    Jones, D.R.2    Masters, A.R.3    Xu, C.4    Guo, Y.5    Desta, Z.6
  • 18
    • 70349108450 scopus 로고    scopus 로고
    • Glururonidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine
    • Belanger AS, Caron P, Harvey M, Zimmerman PA, Mehlotra RK, Guillemette C. Glururonidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine. Drug Metab Dispos. 2009;37(9):1793-1796.
    • (2009) Drug Metab Dispos , vol.37 , Issue.9 , pp. 1793-1796
    • Belanger, A.S.1    Caron, P.2    Harvey, M.3    Zimmerman, P.A.4    Mehlotra, R.K.5    Guillemette, C.6
  • 19
    • 34250764311 scopus 로고    scopus 로고
    • Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro
    • Desta A, Saussele T, Ward B, et al. Impact of CYP2B6 polymorphism on hepatic efavirenz metabolism in vitro. Pharmacogenomics. 2007;8(6):547-558.
    • (2007) Pharmacogenomics , vol.8 , Issue.6 , pp. 547-558
    • Desta, A.1    Saussele, T.2    Ward, B.3
  • 20
    • 80052143211 scopus 로고    scopus 로고
    • Polymorphic variants of Cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) exhibit altered rates of metabolism for bupropion and efavirenz: A charge-reversal mutation in the K139E variant (CYP2B6.8) impairs formation of a functional cytochrome P450 reductase complex
    • Zhang H, Sridar C, Kenaan C, Amunugama H, Ballou DP, Hollenberg PF. Polymorphic variants of Cytochrome P450 2B6 (CYP2B6.4-CYP2B6.9) exhibit altered rates of metabolism for bupropion and efavirenz: a charge-reversal mutation in the K139E variant (CYP2B6.8) impairs formation of a functional cytochrome P450 reductase complex. J Pharmacol Exp Ther. 2001;338(3):803-809.
    • (2001) J Pharmacol Exp Ther , vol.338 , Issue.3 , pp. 803-809
    • Zhang, H.1    Sridar, C.2    Kenaan, C.3    Amunugama, H.4    Ballou, D.P.5    Hollenberg, P.F.6
  • 21
    • 40049092364 scopus 로고    scopus 로고
    • High prevalence of the CYP2B6 516G--.T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe
    • Nyakutira C, Roshammar D, Chigutsa E, et al. High prevalence of the CYP2B6 516G--.T(*6) variant and effect on the population pharmacokinetics of efavirenz in HIV/AIDS outpatients in Zimbabwe. Eur J Clin Pharmacol. 2008;64(4):357-365.
    • (2008) Eur J Clin Pharmacol , vol.64 , Issue.4 , pp. 357-365
    • Nyakutira, C.1    Roshammar, D.2    Chigutsa, E.3
  • 22
    • 34548033928 scopus 로고    scopus 로고
    • CYP2B6 983T.C polymorphism is prevalent in West Africa but absent in Papua New Guinea: Implications for HIV/AIDS treatment
    • Mehlotra RK, Bockarie MJ, Zimmerman PA. CYP2B6 983T.C polymorphism is prevalent in West Africa but absent in Papua New Guinea: implications for HIV/AIDS treatment. Br J Clin Pharmacol. 2007;64(3):391-395.
    • (2007) Br J Clin Pharmacol , vol.64 , Issue.3 , pp. 391-395
    • Mehlotra, R.K.1    Bockarie, M.J.2    Zimmerman, P.A.3
  • 24
    • 35348923463 scopus 로고    scopus 로고
    • Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6*6 and *26
    • Gatanaga H, Hayashida T, Tsuchiya K, et al. Successful efavirenz dose reduction in HIV type 1-infected individuals with cytochrome P450 2B6*6 and *26. Clin Infect Dis. 2007;45(9):1230-1237.
    • (2007) Clin Infect Dis , vol.45 , Issue.9 , pp. 1230-1237
    • Gatanaga, H.1    Hayashida, T.2    Tsuchiya, K.3
  • 25
    • 77955685573 scopus 로고    scopus 로고
    • Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: An AIDS Clinical Trials Group study
    • Ribaudo HJ, Liu H, Schwab M, et al. Effect of CYP2B6, ABCB1, and CYP3A5 polymorphisms on efavirenz pharmacokinetics and treatment response: an AIDS Clinical Trials Group study. J Infect Dis. 2010;202(5):717-722.
    • (2010) J Infect Dis , vol.202 , Issue.5 , pp. 717-722
    • Ribaudo, H.J.1    Liu, H.2    Schwab, M.3
  • 26
    • 77957145661 scopus 로고    scopus 로고
    • Influence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1 infected patients
    • Elens L, Vandercam B, Yombi JC, Lison D, Wallemacq P, Haufroid V. Influence of host genetic factors on efavirenz plasma and intracellular pharmacokinetics in HIV-1 infected patients. Pharmacogenomics. 2010;11(9):1223-1234.
    • (2010) Pharmacogenomics , vol.11 , Issue.9 , pp. 1223-1234
    • Elens, L.1    Vandercam, B.2    Yombi, J.C.3    Lison, D.4    Wallemacq, P.5    Haufroid, V.6
  • 27
    • 41149092923 scopus 로고    scopus 로고
    • Impact of CYP2B6 983T.C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients
    • Wyen C, Hendra H, Vogel M, et al. Impact of CYP2B6 983T.C polymorphism on non-nucleoside reverse transcriptase inhibitor plasma concentrations in HIV-infected patients. J Antimicrob Chemother. 2008;61(4):914-918.
    • (2008) J Antimicrob Chemother , vol.61 , Issue.4 , pp. 914-918
    • Wyen, C.1    Hendra, H.2    Vogel, M.3
  • 28
    • 33847793822 scopus 로고    scopus 로고
    • Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV-infected patients in Uganda
    • Penzak SR, Kabuye G, Mugyenyi P, et al. Cytochrome P450 2B6 (CYP2B6) G516T influences nevirapine plasma concentrations in HIV-infected patients in Uganda. HIV Med. 2007;8(2):86-91.
    • (2007) HIV Med , vol.8 , Issue.2 , pp. 86-91
    • Penzak, S.R.1    Kabuye, G.2    Mugyenyi, P.3
  • 29
    • 70349432367 scopus 로고    scopus 로고
    • CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Portau-Prince, Haiti
    • Leger P, Dillingham R, Beauhamais CA, et al. CYP2B6 variants and plasma efavirenz concentrations during antiretroviral therapy in Portau-Prince, Haiti. J Infect Dis. 2009;200(6):955-964.
    • (2009) J Infect Dis , vol.200 , Issue.6 , pp. 955-964
    • Leger, P.1    Dillingham, R.2    Beauhamais, C.A.3
  • 30
    • 65449118348 scopus 로고    scopus 로고
    • Cytochrome P450 2B6 516G--.T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population
    • Mahungu T, Smith C, Turner F, et al. Cytochrome P450 2B6 516G--.T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population. HIV Med. 2009;10(5):310-317.
    • (2009) HIV Med , vol.10 , Issue.5 , pp. 310-317
    • Mahungu, T.1    Smith, C.2    Turner, F.3
  • 31
    • 37349034567 scopus 로고    scopus 로고
    • CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1-infected children
    • Saitoh A, Sarles E, Capparelli E, et al. CYP2B6 genetic variants are associated with nevirapine pharmacokinetics and clinical response in HIV-1-infected children. AIDS. 2007;21(16):2191-2199.
    • (2007) AIDS , vol.21 , Issue.16 , pp. 2191-2199
    • Saitoh, A.1    Sarles, E.2    Capparelli, E.3
  • 32
    • 31044456584 scopus 로고    scopus 로고
    • Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: An Adult AIDS Clinical Trials Group Study
    • Ribaudo HJ, Haas DW, Tierney C, et al. Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: an Adult AIDS Clinical Trials Group Study. Clin Infect Dis. 2006;42(3):401-407.
    • (2006) Clin Infect Dis , vol.42 , Issue.3 , pp. 401-407
    • Ribaudo, H.J.1    Haas, D.W.2    Tierney, C.3
  • 33
    • 19944428456 scopus 로고    scopus 로고
    • Pharmacogenetics of efavirenz and central nervous sytem side effects: An Adult AIDS Clinical Trials Group Study
    • Haas DW, Ribaudo HJ, Kim RB, et al. Pharmacogenetics of efavirenz and central nervous sytem side effects: an Adult AIDS Clinical Trials Group Study. AIDS. 2004;18(18):2391-4000.
    • (2004) AIDS , vol.18 , Issue.18 , pp. 2391-4000
    • Haas, D.W.1    Ribaudo, H.J.2    Kim, R.B.3
  • 34
    • 62949173597 scopus 로고    scopus 로고
    • CYP2B6 G516T polymorphism but not rifampin coadministration influences steady-state pharmacokinetics of efavirenz in human immunodefiency virus-infected patients in South India
    • Ramachandran G, Hemanth Kumar AK, Rajasekaran S, et al. CYP2B6 G516T polymorphism but not rifampin coadministration influences steady-state pharmacokinetics of efavirenz in human immunodefiency virus-infected patients in South India. Antimicrob Agents Chemother. 2009;53(3):863-868.
    • (2009) Antimicrob Agents Chemother , vol.53 , Issue.3 , pp. 863-868
    • Ramachandran, G.1    Hemanth, K.A.K.2    Rajasekaran, S.3
  • 35
    • 20244364148 scopus 로고    scopus 로고
    • Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients
    • Rotger M, Colombo S, Furrer H, et al. Influence of CYP2B6 polymorphism on plasma and intracellular concentrations and toxicity of efavirenz and nevirapine in HIV-infected patients. Pharmacogent Genomics. 2005;15(1):1-5.
    • (2005) Pharmacogent Genomics , vol.15 , Issue.1 , pp. 1-5
    • Rotger, M.1    Colombo, S.2    Furrer, H.3
  • 36
    • 62549089177 scopus 로고    scopus 로고
    • Association of high T allele frequence of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine
    • Ramachandran G, Ramesh K, Hemanth Kumar AK, et al. Association of high T allele frequence of CYP2B6 G516T polymorphism among ethnic south Indian HIV-infected patients with elevated plasma efavirenz and nevirapine. J Antimicrob Chemother. 2009;63(4):841-843.
    • (2009) J Antimicrob Chemother , vol.63 , Issue.4 , pp. 841-843
    • Ramachandran, G.1    Ramesh, K.2    Hemanth, K.A.K.3
  • 37
    • 2942551228 scopus 로고    scopus 로고
    • Homozygous CYP2B6*6(Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenzcontaining regimens
    • Tsuchiya K, Gatanaga H, Tachikawa N, et al. Homozygous CYP2B6*6(Q172H and K262R) correlates with high plasma efavirenz concentrations in HIV-1 patients treated with standard efavirenzcontaining regimens. Biochem Biophys Res Commun. 2004;319(4): 1322-1326.
    • (2004) Biochem Biophys Res Commun , vol.319 , Issue.4 , pp. 1322-1326
    • Tsuchiya, K.1    Gatanaga, H.2    Tachikawa, N.3
  • 38
    • 65649091303 scopus 로고    scopus 로고
    • Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African Americans
    • Haas DW, Gebretsadik T, Mayo G, et al. Associations between CYP2B6 polymorphisms and pharmacokinetics after a single dose of nevirapine or efavirenz in African Americans. J Infect Dis. 2009;199(6): 872-880.
    • (2009) J Infect Dis , vol.199 , Issue.6 , pp. 872-880
    • Haas, D.W.1    Gebretsadik, T.2    Mayo, G.3
  • 39
    • 77957287517 scopus 로고    scopus 로고
    • CYP2B6 polymorphism and nonnucleoside reverse transcriptase inhibitor plasma concentrations in Chinese HIVinfected patients
    • Chen J, Sun J, Ma Q, et al. CYP2B6 polymorphism and nonnucleoside reverse transcriptase inhibitor plasma concentrations in Chinese HIVinfected patients. Ther Drug Monit. 2010;32(5):573-578.
    • (2010) Ther Drug Monit , vol.32 , Issue.5 , pp. 573-578
    • Chen, J.1    Sun, J.2    Ma, Q.3
  • 40
    • 33644588715 scopus 로고    scopus 로고
    • Identification of a novel specific CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz
    • Wang J, Sonnerborg A, Rane A, et al. Identification of a novel specific CYP2B6 allele in Africans causing impaired metabolism of the HIV drug efavirenz. Pharmacogenetic Genomics. 2006;16(3):191-198.
    • (2006) Pharmacogenetic Genomics , vol.16 , Issue.3 , pp. 191-198
    • Wang, J.1    Sonnerborg, A.2    Rane, A.3
  • 41
    • 70449334327 scopus 로고    scopus 로고
    • A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans
    • Mukonzo JK, Roshammar D, Waako P, et al. A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans. Br J Clin Pharmacol. 2009;68(5):690-696.
    • (2009) Br J Clin Pharmacol , vol.68 , Issue.5 , pp. 690-696
    • Mukonzo, J.K.1    Roshammar, D.2    Waako, P.3
  • 42
    • 33947382259 scopus 로고    scopus 로고
    • Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIVinfected individuals
    • Rotger M, Tegude H, Colombo S, et al. Predictive value of known and novel alleles of CYP2B6 for efavirenz plasma concentrations in HIVinfected individuals. Clin Pharmacol Ther. 2007;81(4):557-566.
    • (2007) Clin Pharmacol Ther , vol.81 , Issue.4 , pp. 557-566
    • Rotger, M.1    Tegude, H.2    Colombo, S.3
  • 43
    • 34648837873 scopus 로고    scopus 로고
    • Partial deletion of CYP2B6 owing to unequal crossover with CYP2B7
    • Rotger M, Saumoy M, Zhang K, et al. Partial deletion of CYP2B6 owing to unequal crossover with CYP2B7. Pharmacogenet Genomics. 2007;17(10):885-890.
    • (2007) Pharmacogenet Genomics , vol.17 , Issue.10 , pp. 885-890
    • Rotger, M.1    Saumoy, M.2    Zhang, K.3
  • 44
    • 77955674979 scopus 로고    scopus 로고
    • Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort
    • Carr DF, la Porte CJ, Mirmohamed M, Owen A, Cortes CP. Haplotype structure of CYP2B6 and association with plasma efavirenz concentrations in a Chilean HIV cohort. J Antimicrob Chemother. 2010;65(9):1889-1893.
    • (2010) J Antimicrob Chemother , vol.65 , Issue.9 , pp. 1889-1893
    • Carr, D.F.1    la Porte, C.J.2    Mirmohamed, M.3    Owen, A.4    Cortes, C.P.5
  • 45
    • 27944460707 scopus 로고    scopus 로고
    • Pharmacogenetics of longterm responses to antiretroviral regimens containing efavirenz and/or nelfinavir: An Adult Aids Clinical Trials Group Study
    • Haas DW, Smeaton LM, Shafer RW, et al. Pharmacogenetics of longterm responses to antiretroviral regimens containing efavirenz and/or nelfinavir: an Adult Aids Clinical Trials Group Study. J Infect Dis. 2005;192(11):1931-1942.
    • (2005) J Infect Dis , vol.192 , Issue.11 , pp. 1931-1942
    • Haas, D.W.1    Smeaton, L.M.2    Shafer, R.W.3
  • 46
    • 33750312905 scopus 로고    scopus 로고
    • Multilocus genetic interactions and response to efavirenz-containing regimens: An adult AIDS clinical trials group study
    • Motsinger AA, Ritchie MD, Shafer RW, et al. Multilocus genetic interactions and response to efavirenz-containing regimens: an adult AIDS clinical trials group study. Pharmacogent Genomics. 2006;16(11):837-845.
    • (2006) Pharmacogent Genomics , vol.16 , Issue.11 , pp. 837-845
    • Motsinger, A.A.1    Ritchie, M.D.2    Shafer, R.W.3
  • 47
    • 0037022006 scopus 로고    scopus 로고
    • Response to antiretroviral treatment in HIV-1 infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetics study
    • Fellay J, Marzolini C, Meaden ER, et al. Response to antiretroviral treatment in HIV-1 infected individuals with allelic variants of the multidrug resistance transporter 1: a pharmacogenetics study. Lancet. 2002;259(9300):30-36.
    • (2002) Lancet , vol.259 , Issue.9300 , pp. 30-36
    • Fellay, J.1    Marzolini, C.2    Meaden, E.R.3
  • 48
    • 79952607777 scopus 로고    scopus 로고
    • In silico prediction of efavirenz and rifampicin drug-drug interaction considering weight and CYP2B6 phenotype
    • Rekic D, Roshammar D, Mukonzo J, Ashton M. In silico prediction of efavirenz and rifampicin drug-drug interaction considering weight and CYP2B6 phenotype. Br J Clin Pharmacol. 2011;71(4):536-543.
    • (2011) Br J Clin Pharmacol , vol.71 , Issue.4 , pp. 536-543
    • Rekic, D.1    Roshammar, D.2    Mukonzo, J.3    Ashton, M.4
  • 49
    • 79551594988 scopus 로고    scopus 로고
    • Paradoxically elevated efavirenz concentrations in HIV/tuberculosis co-infected patients with CYP2B6 516TT genotype on rifampin-containing antituberculous therapy
    • Kawara A, Lartey M, Sagoe KW, Court MH. Paradoxically elevated efavirenz concentrations in HIV/tuberculosis co-infected patients with CYP2B6 516TT genotype on rifampin-containing antituberculous therapy. AIDS. 2011;25(3):388-390.
    • (2011) AIDS , vol.25 , Issue.3 , pp. 388-390
    • Kawara, A.1    Lartey, M.2    Sagoe, K.W.3    Court, M.H.4
  • 50
    • 1642523162 scopus 로고    scopus 로고
    • Polymorphisms in human MDR1 (P-glycoprotein): Recent advances and clinical relevance
    • Marzolini C, Paus E, Buclin T, Kim RB. Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance. Clin Pharmacol Ther. 2004;75(1):13-33.
    • (2004) Clin Pharmacol Ther , vol.75 , Issue.1 , pp. 13-33
    • Marzolini, C.1    Paus, E.2    Buclin, T.3    Kim, R.B.4
  • 51
    • 19944418250 scopus 로고    scopus 로고
    • Influence of singlenucleotide polymorphisms in the multidrug resistance-1 gene on the cellular exposure of nelfinavir and its clinical implication for highly active antiretroviral therapy
    • Zhu D, Taguchi-Nakamura H, Goto M, et al. Influence of singlenucleotide polymorphisms in the multidrug resistance-1 gene on the cellular exposure of nelfinavir and its clinical implication for highly active antiretroviral therapy. Antivir Ther. 2004;9(6):929-935.
    • (2004) Antivir Ther , vol.9 , Issue.6 , pp. 929-935
    • Zhu, D.1    Taguchi-Nakamura, H.2    Goto, M.3
  • 52
    • 3142751539 scopus 로고    scopus 로고
    • No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment
    • Winzer R, Langmann P, Zilly M, et al. No influence of the P-glycoprotein genotype (MDR1 C3435T) on plasma levels of lopinavir and efavirenz during antiretroviral treatment. Eur J Med Res. 2003;8(12): 531-534.
    • (2003) Eur J Med Res , vol.8 , Issue.12 , pp. 531-534
    • Winzer, R.1    Langmann, P.2    Zilly, M.3
  • 53
    • 0037462209 scopus 로고    scopus 로고
    • Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response
    • Brumme ZL, Dong WW, Chan KJ, et al. Influence of polymorphisms within the CX3CR1 and MDR-1 genes on initial antiretroviral therapy response. AIDS. 2003;17(2):201-208.
    • (2003) AIDS , vol.17 , Issue.2 , pp. 201-208
    • Brumme, Z.L.1    Dong, W.W.2    Chan, K.J.3
  • 54
    • 74549195545 scopus 로고    scopus 로고
    • Nonnucleoside reverse transcriptase inhibitor resistance and the role of the second-generation agents
    • Adams J, Patel N, Mankaryous N, et al. Nonnucleoside reverse transcriptase inhibitor resistance and the role of the second-generation agents. Ann Pharmacother. 2010;44:157-165.
    • (2010) Ann Pharmacother , vol.44 , pp. 157-165
    • Adams, J.1    Patel, N.2    Mankaryous, N.3
  • 56
    • 53349160769 scopus 로고    scopus 로고
    • Association of a singlenucleotide polymorphism in the pregnane X receptor (PXR 63396 C.T) with reduced concentrations of unboosted atazanavir
    • Siccardi M, D'Avolio A, Baietto L, et al. Association of a singlenucleotide polymorphism in the pregnane X receptor (PXR 63396 C.T) with reduced concentrations of unboosted atazanavir. Clin Infect Dis. 2008;47(9):1222-1225.
    • (2008) Clin Infect Dis , vol.47 , Issue.9 , pp. 1222-1225
    • Siccardi, M.1    D'avolio, A.2    Baietto, L.3
  • 57
    • 78649673343 scopus 로고    scopus 로고
    • Population pharmacokinetic modelling of the association between 63396 C.T pregnane X receptor polymorphism and unboosted atazanavir clearance
    • Shipani A, Siccardi M, D'Avolio A, et al. Population pharmacokinetic modelling of the association between 63396 C.T pregnane X receptor polymorphism and unboosted atazanavir clearance. Antimicrob Agents Chemother. 2010;54(12):5242-5250.
    • (2010) Antimicrob Agents Chemother , vol.54 , Issue.12 , pp. 5242-5250
    • Shipani, A.1    Siccardi, M.2    D'avolio, A.3
  • 58
    • 78650210692 scopus 로고    scopus 로고
    • Nuclear Receptor-Mediated Induction of CYP450 by Antiretrovirals: Functional Consequences of N1I2(PXR) Polymorphisms and Differential Prevalence in Whites and Sub-Saharan Africans
    • Svard J, Spiers JP, Mulcahy F, Hennessy M. Nuclear Receptor-Mediated Induction of CYP450 by Antiretrovirals: Functional Consequences of N1I2(PXR) Polymorphisms and Differential Prevalence in Whites and Sub-Saharan Africans. J Acquir Immune Defic Syndr. 2010;55(5):536-549.
    • (2010) J Acquir Immune Defic Syndr , vol.55 , Issue.5 , pp. 536-549
    • Svard, J.1    Spiers, J.P.2    Mulcahy, F.3    Hennessy, M.4
  • 59
    • 75649091119 scopus 로고    scopus 로고
    • HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms
    • Hartkoorn RC, Kwan WS, Shallcross V, et al. HIV protease inhibitors are substrates for OATP1A2, OATP1B1 and OATP1B3 and lopinavir plasma concentrations are influenced by SLCO1B1 polymorphisms. Pharmacogenet Genomics. 2010;20(2):112-120.
    • (2010) Pharmacogenet Genomics , vol.20 , Issue.2 , pp. 112-120
    • Hartkoorn, R.C.1    Kwan, W.S.2    Shallcross, V.3
  • 60
    • 72949097439 scopus 로고    scopus 로고
    • The impact of SLCO1B1 polymorphisms on the plasma concentrations of lopinavir and ritonavir in HIV-infected men
    • Kohlrausch FB, de Cassia Estrela R, Barroso PF, Suarez-Kurtz G. The impact of SLCO1B1 polymorphisms on the plasma concentrations of lopinavir and ritonavir in HIV-infected men. Br J Clin Pharmacol. 2010;69(1):95-98.
    • (2010) Br J Clin Pharmacol , vol.69 , Issue.1 , pp. 95-98
    • Kohlrausch, F.B.1    de Cassia, E.R.2    Barroso, P.F.3    Suarez-Kurtz, G.4
  • 61
    • 77950787858 scopus 로고    scopus 로고
    • ADME pharmacogenetics: Investigation of the pharmacokinetics of the antiretroviral agent lopinavir co-formulated with ritonavir
    • Lubomirov R, di Iulio J, Fayet A, et al. ADME pharmacogenetics: investigation of the pharmacokinetics of the antiretroviral agent lopinavir co-formulated with ritonavir. Pharmacogenet Genomics. 2010;20(4):217-230.
    • (2010) Pharmacogenet Genomics , vol.20 , Issue.4 , pp. 217-230
    • Lubomirov, R.1    di Iulio, J.2    Fayet, A.3
  • 62
    • 67349217885 scopus 로고    scopus 로고
    • Pharmacokinetics of raltegravir in individuals with UGT1A1 polymorphisms
    • Wenning LA, Petry AS, Kost JT, et al. Pharmacokinetics of raltegravir in individuals with UGT1A1 polymorphisms. Clin Pharmacol Ther. 2009;85(6):623-627.
    • (2009) Clin Pharmacol Ther , vol.85 , Issue.6 , pp. 623-627
    • Wenning, L.A.1    Petry, A.S.2    Kost, J.T.3
  • 63
    • 54849145400 scopus 로고    scopus 로고
    • Subgroup analysis of maraviroc in previously treated R5 HIV-1 infection
    • Fakenheuer G, Nelson M, Lazzarin A, et al. Subgroup analysis of maraviroc in previously treated R5 HIV-1 infection. N Eng J Med. 2008;359(14):1442-1455.
    • (2008) N Eng J Med , vol.359 , Issue.14 , pp. 1442-1455
    • Fakenheuer, G.1    Nelson, M.2    Lazzarin, A.3
  • 64
    • 0036246069 scopus 로고    scopus 로고
    • Risk factor analysis of hypersensitivity reactions to abacavir
    • Symonds W, Cutrell A, Edwards M, et al. Risk factor analysis of hypersensitivity reactions to abacavir. Clin Ther. 2002;24(4):565-573.
    • (2002) Clin Ther , vol.24 , Issue.4 , pp. 565-573
    • Symonds, W.1    Cutrell, A.2    Edwards, M.3
  • 65
    • 0034798191 scopus 로고    scopus 로고
    • Hypersensitivity related to abacavir in two members of a family
    • Peyieere H, Nicolas J, Siffert M, et al. Hypersensitivity related to abacavir in two members of a family. Ann Pharmacother. 2001;35(10): 1291-1292.
    • (2001) Ann Pharmacother , vol.35 , Issue.10 , pp. 1291-1292
    • Peyieere, H.1    Nicolas, J.2    Siffert, M.3
  • 66
    • 12144291646 scopus 로고    scopus 로고
    • Association of genetic variation in HLA-B region with hypersensitivity to abacavir in some, but not all, populations
    • Hughes AR, Mosteller N, Bansal AT, et al. Association of genetic variation in HLA-B region with hypersensitivity to abacavir in some, but not all, populations. Pharmacogenomics. 2004;5(2):203-211.
    • (2004) Pharmacogenomics , vol.5 , Issue.2 , pp. 203-211
    • Hughes, A.R.1    Mosteller, N.2    Bansal, A.T.3
  • 67
    • 20844462378 scopus 로고    scopus 로고
    • Abacavir versus zidovudine combined with lamivudine and efavirenz for the treatment of antiretroviralnaive HIV-infected adults
    • Dejesus E, Herreera G, Teofilo E, et al. Abacavir versus zidovudine combined with lamivudine and efavirenz for the treatment of antiretroviralnaive HIV-infected adults. Clin Infect Dis. 2004;39(7):1038-1046.
    • (2004) Clin Infect Dis , vol.39 , Issue.7 , pp. 1038-1046
    • Dejesus, E.1    Herreera, G.2    Teofilo, E.3
  • 68
    • 33747102040 scopus 로고    scopus 로고
    • Three-versus four-drug antiretroviral regimens for the initial treatment of HIV-1 infection: A randomized controlled trial
    • Guilick R, Ribaudo H, Shikuma CM, et al. Three-versus four-drug antiretroviral regimens for the initial treatment of HIV-1 infection: a randomized controlled trial. JAMA. 2006;296(7):769-781.
    • (2006) JAMA , vol.296 , Issue.7 , pp. 769-781
    • Guilick, R.1    Ribaudo, H.2    Shikuma, C.M.3
  • 69
    • 39449098453 scopus 로고    scopus 로고
    • Twenty-four week safety and tolerability of nevirapine vs abacavir in combination with zidovudine/lamivudine as first-line antiretroviral therapy: A randomized double-blind trial (NORA)
    • Dart Trial Team. Twenty-four week safety and tolerability of nevirapine vs abacavir in combination with zidovudine/lamivudine as first-line antiretroviral therapy: a randomized double-blind trial (NORA). Trop Med Int Health. 2008;13(1):6-16.
    • (2008) Trop Med Int Health , vol.13 , Issue.1 , pp. 6-16
    • Team, D.T.1
  • 70
    • 34447335007 scopus 로고    scopus 로고
    • Diagnosis of abacavir hypersensitivity reactions among patients receiving abacavir in two blinded studies
    • Hernandez J, Cutrell A, Bonny T, et al. Diagnosis of abacavir hypersensitivity reactions among patients receiving abacavir in two blinded studies. Antivir Ther. 2003;8:L88.
    • (2003) Antivir Ther , vol.8
    • Hernandez, J.1    Cutrell, A.2    Bonny, T.3
  • 71
    • 0037045073 scopus 로고    scopus 로고
    • Utility of patch testing in patients with hypersensitivity reaction associated with abacavir
    • Phillips EJ, Sullivan JR, Knowles R, Shear NH. Utility of patch testing in patients with hypersensitivity reaction associated with abacavir. AIDS. 2002;16(16):2223-2225.
    • (2002) AIDS , vol.16 , Issue.16 , pp. 2223-2225
    • Phillips, E.J.1    Sullivan, J.R.2    Knowles, R.3    Shear, N.H.4
  • 72
    • 20644470742 scopus 로고    scopus 로고
    • Clinical and immunogenetic correlates of abacavir hypersensitivity
    • Phillips EJ, Wong GA, Kaul R, et al. Clinical and immunogenetic correlates of abacavir hypersensitivity. AIDS. 2005;19(9):979-981.
    • (2005) AIDS , vol.19 , Issue.9 , pp. 979-981
    • Phillips, E.J.1    Wong, G.A.2    Kaul, R.3
  • 73
    • 44449113606 scopus 로고    scopus 로고
    • A review of drug patch testing and implications for HIV clinicians
    • Shear NH, Milipied B, Bruynzeel DP, Phillips E. A review of drug patch testing and implications for HIV clinicians. AIDS. 2008;22(9): 999-1007.
    • (2008) AIDS , vol.22 , Issue.9 , pp. 999-1007
    • Shear, N.H.1    Milipied, B.2    Bruynzeel, D.P.3    Phillips, E.4
  • 74
    • 38949196447 scopus 로고    scopus 로고
    • HLA-B*5701screening for hypersensitivity to abacavir
    • Mallal S, Phillips E, Carosi G, et al. HLA-B*5701screening for hypersensitivity to abacavir. N Engl J Med. 2008;358(6):568-579.
    • (2008) N Engl J Med , vol.358 , Issue.6 , pp. 568-579
    • Mallal, S.1    Phillips, E.2    Carosi, G.3
  • 75
    • 42549131532 scopus 로고    scopus 로고
    • High sensitivity of human leukocyte antigen-B*5701 as a marker for immunogenetically confirmed abacavir hypersensitivity in white and black patients
    • Saag M, Balu R, Phillips E, et al. High sensitivity of human leukocyte antigen-B*5701 as a marker for immunogenetically confirmed abacavir hypersensitivity in white and black patients. Clin Infect Dis. 2008;46(7):1111-1118.
    • (2008) Clin Infect Dis , vol.46 , Issue.7 , pp. 1111-1118
    • Saag, M.1    Balu, R.2    Phillips, E.3
  • 76
    • 33745295856 scopus 로고    scopus 로고
    • Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV cohort study
    • Rauch A, Nolan D, Martin A, et al. Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV cohort study. Clin Infect Dis. 2006;43(1):99-102.
    • (2006) Clin Infect Dis , vol.43 , Issue.1 , pp. 99-102
    • Rauch, A.1    Nolan, D.2    Martin, A.3
  • 77
    • 34247636623 scopus 로고    scopus 로고
    • Prospective genetic screening for human leuckocyte antigen-B*5701 avoid abacavir hypersensitivity in the ethnically mixed French HIV population
    • Zucman D, Truchis P, Majerholc C, et al. Prospective genetic screening for human leuckocyte antigen-B*5701 avoid abacavir hypersensitivity in the ethnically mixed French HIV population. J Acquir Immune Defic Syndr. 2007;45(1):1-3.
    • (2007) J Acquir Immune Defic Syndr , vol.45 , Issue.1 , pp. 1-3
    • Zucman, D.1    Truchis, P.2    Majerholc, C.3
  • 78
    • 34248396533 scopus 로고    scopus 로고
    • Screening for HLA-B*5701 reduces the frequency of abacavir hypersensitivity reactions
    • Reeves I, Churchill D, Fisher M. Screening for HLA-B*5701 reduces the frequency of abacavir hypersensitivity reactions. Antiviral Ther. 2006;11:L11.
    • (2006) Antiviral Ther , vol.11
    • Reeves, I.1    Churchill, D.2    Fisher, M.3
  • 80
    • 72649086454 scopus 로고    scopus 로고
    • Successful implementation of a national HLA-B*5701 genetic testing service in Canada
    • Lalonde RG, Thomas R, Rachlis A, et al. Successful implementation of a national HLA-B*5701 genetic testing service in Canada. Tissue Antigens. 2009;75(1):12-18.
    • (2009) Tissue Antigens , vol.75 , Issue.1 , pp. 12-18
    • Lalonde, R.G.1    Thomas, R.2    Rachlis, A.3
  • 81
    • 36349024340 scopus 로고    scopus 로고
    • Prospective HLA-B*5701 screening and abacavir hypersensitivity: A single centre experience
    • Waters LJ, Mandalia S, Gazzard B, et al. Prospective HLA-B*5701 screening and abacavir hypersensitivity: a single centre experience. AIDS. 2007;21(18):2533-2534.
    • (2007) AIDS , vol.21 , Issue.18 , pp. 2533-2534
    • Waters, L.J.1    Mandalia, S.2    Gazzard, B.3
  • 82
    • 52249120368 scopus 로고    scopus 로고
    • First large multicentre open-label study utilizing HLA-B*5701screening for abacavir hypersensitivity in North America
    • Young B, Squires K, Patel P, et al. First large multicentre open-label study utilizing HLA-B*5701screening for abacavir hypersensitivity in North America. AIDS. 2008;22(13):1673-1675.
    • (2008) AIDS , vol.22 , Issue.13 , pp. 1673-1675
    • Young, B.1    Squires, K.2    Patel, P.3
  • 83
    • 12144287198 scopus 로고    scopus 로고
    • Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant
    • Martin AM, Nolan D, Gaudieri S, et al. Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proc Natl Acad Sci U S A. 2004;101(12):4180-4185.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.12 , pp. 4180-4185
    • Martin, A.M.1    Nolan, D.2    Gaudieri, S.3
  • 84
    • 44649104544 scopus 로고    scopus 로고
    • Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity
    • Chessman D, Kostenko L, Lethborg T, et al. Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity. Immunity. 2008;28(6):822-832.
    • (2008) Immunity , vol.28 , Issue.6 , pp. 822-832
    • Chessman, D.1    Kostenko, L.2    Lethborg, T.3
  • 85
    • 20144380564 scopus 로고    scopus 로고
    • HLA-B*5701 typing by sequencespecific amplification: Validation and comparison with sequence-based typing
    • Martin AM, Nolan D, Mallal S. HLA-B*5701 typing by sequencespecific amplification: validation and comparison with sequence-based typing. Tissue Antigens. 2005;65(6):571-574.
    • (2005) Tissue Antigens , vol.65 , Issue.6 , pp. 571-574
    • Martin, A.M.1    Nolan, D.2    Mallal, S.3
  • 86
    • 34250001181 scopus 로고    scopus 로고
    • HLA-B*5701 typing: Evaluation of an allele-specific polymerase chain melting assay
    • Hammond E, Mamotte C, Nolan D, et al. HLA-B*5701 typing: evaluation of an allele-specific polymerase chain melting assay. Tissue Antigens. 2007;70(1):58-61.
    • (2007) Tissue Antigens , vol.70 , Issue.1 , pp. 58-61
    • Hammond, E.1    Mamotte, C.2    Nolan, D.3
  • 87
    • 33645950777 scopus 로고    scopus 로고
    • A sensitive and rapid alternative to HLA typing as a genetic screening test for abacavir hypersensitivity syndrome
    • Martin AM, Krueger R, Almeida CA, et al. A sensitive and rapid alternative to HLA typing as a genetic screening test for abacavir hypersensitivity syndrome. Pharmacogenet Genomics. 2006;16(5):353-357.
    • (2006) Pharmacogenet Genomics , vol.16 , Issue.5 , pp. 353-357
    • Martin, A.M.1    Krueger, R.2    Almeida, C.A.3
  • 88
    • 79955535238 scopus 로고    scopus 로고
    • Novel sensitive, specific and rapid pharmacogenomic test for the prediction of abacavir hypersensitivity reaction: HLA-B*5701 detection by real-time PCR
    • Dello Russo C, Lisi L, Lofaro A, et al. Novel sensitive, specific and rapid pharmacogenomic test for the prediction of abacavir hypersensitivity reaction: HLA-B*5701 detection by real-time PCR. Pharmacogenomics. 2011;12(4):567-576.
    • (2011) Pharmacogenomics , vol.12 , Issue.4 , pp. 567-576
    • Dello, R.C.1    Lisi, L.2    Lofaro, A.3
  • 89
    • 79958694904 scopus 로고    scopus 로고
    • Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity
    • Kostenko L, Kjer-Nielsen L, Nicholson I, et al. Rapid screening for the detection of HLA-B57 and HLA-B58 in prevention of drug hypersensitivity. Tissue Antigens. 2011;78(1):11-20.
    • (2011) Tissue Antigens , vol.78 , Issue.1 , pp. 11-20
    • Kostenko, L.1    Kjer-Nielsen, L.2    Nicholson, I.3
  • 90
    • 36148966933 scopus 로고    scopus 로고
    • External quality assessment of HLA-B*5701 reporting and international multicentre survey
    • Hammond E, Almeida CA, Mamotte C, et al. External quality assessment of HLA-B*5701 reporting and international multicentre survey. Antivir Ther. 2007;12(7):1027-1032.
    • (2007) Antivir Ther , vol.12 , Issue.7 , pp. 1027-1032
    • Hammond, E.1    Almeida, C.A.2    Mamotte, C.3
  • 92
    • 12144260460 scopus 로고    scopus 로고
    • Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T cell counts
    • Martin AM, Nolan D, James I, et al. Predisposition to nevirapine hypersensitivity associated with HLA-DRB1*0101 and abrogated by low CD4 T cell counts. AIDS. 2005;19(1):97-99.
    • (2005) AIDS , vol.19 , Issue.1 , pp. 97-99
    • Martin, A.M.1    Nolan, D.2    James, I.3
  • 93
    • 33746767604 scopus 로고    scopus 로고
    • HLA-dependent hypersensitivity to nevirapine in Sardinian HIV patients
    • Littera R, Carcassi C, Masala A, et al. HLA-dependent hypersensitivity to nevirapine in Sardinian HIV patients. AIDS. 2006;20(12):1621-1626.
    • (2006) AIDS , vol.20 , Issue.12 , pp. 1621-1626
    • Littera, R.1    Carcassi, C.2    Masala, A.3
  • 94
    • 33845945094 scopus 로고    scopus 로고
    • HLA-Cw8 primarily associated with hypersensitivity to nevirapine
    • Gatanaga H, Yazaki H, Tanuma J, et al. HLA-Cw8 primarily associated with hypersensitivity to nevirapine. AIDS. 2007;21(2):264-265.
    • (2007) AIDS , vol.21 , Issue.2 , pp. 264-265
    • Gatanaga, H.1    Yazaki, H.2    Tanuma, J.3
  • 95
    • 59549096348 scopus 로고    scopus 로고
    • HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients
    • Chantarangsu S, Mushiroda T, Mahasirimongkol S, et al. HLA-B*3505 allele is a strong predictor for nevirapine-induced skin adverse drug reactions in HIV-infected Thai patients. Pharmacogent Genomics. 2009;19(2):139-146.
    • (2009) Pharmacogent Genomics , vol.19 , Issue.2 , pp. 139-146
    • Chantarangsu, S.1    Mushiroda, T.2    Mahasirimongkol, S.3
  • 96
    • 79952121425 scopus 로고    scopus 로고
    • HLA-B*35 is associated with nevirapine hypersensitivity in the contemporary Western Australian HIV cohort study
    • Phillips E, Lucas M, Keane N, Lucas A, McKinnon E, Mallal S. HLA-B*35 is associated with nevirapine hypersensitivity in the contemporary Western Australian HIV cohort study. Eur Ann Allergy Clin Immunol. 2010;42:48.
    • (2010) Eur Ann Allergy Clin Immunol , vol.42 , pp. 48
    • Phillips, E.1    Lucas, M.2    Keane, N.3    Lucas, A.4    McKinnon, E.5    Mallal, S.6
  • 97
    • 85027929582 scopus 로고    scopus 로고
    • Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian and European descent
    • Yuan J, Guo S, Hall D, et al. Toxicogenomics of nevirapine-associated cutaneous and hepatic adverse events among populations of African, Asian and European descent. AIDS. 2011;25(10):1271-1280.
    • (2011) AIDS , vol.25 , Issue.10 , pp. 1271-1280
    • Yuan, J.1    Guo, S.2    Hall, D.3
  • 98
    • 33748328070 scopus 로고    scopus 로고
    • Pharmacogenetics of nevirapine-associated hepatotoxicity: An Adult AIDS Clinical Trials Group collaboration
    • Haas DW, Bartlett JA, Anderson JW, et al. Pharmacogenetics of nevirapine-associated hepatotoxicity: an Adult AIDS Clinical Trials Group collaboration. Clin Infect Dis. 2006;43(6):783-786.
    • (2006) Clin Infect Dis , vol.43 , Issue.6 , pp. 783-786
    • Haas, D.W.1    Bartlett, J.A.2    Anderson, J.W.3
  • 99
    • 33748288115 scopus 로고    scopus 로고
    • Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity
    • Ritchie MD, Haas DW, Motsinger AA, et al. Drug transporter and metabolizing enzyme gene variants and nonnucleoside reverse-transcriptase inhibitor hepatotoxicity. Clin Infect Dis. 2006;43(6):779-782.
    • (2006) Clin Infect Dis , vol.43 , Issue.6 , pp. 779-782
    • Ritchie, M.D.1    Haas, D.W.2    Motsinger, A.A.3
  • 100
    • 73549123640 scopus 로고    scopus 로고
    • Nevirapine-induced hepatotoxicity and pharmacogenetics: A retrospective study in a population from Mozambique
    • Ciccacci C, Borgiani P, Ceffa S, et al. Nevirapine-induced hepatotoxicity and pharmacogenetics: a retrospective study in a population from Mozambique. Pharmacogenomics. 2010;11(1):23-31.
    • (2010) Pharmacogenomics , vol.11 , Issue.1 , pp. 23-31
    • Ciccacci, C.1    Borgiani, P.2    Ceffa, S.3
  • 102
    • 39849105346 scopus 로고    scopus 로고
    • HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz
    • Vitezica ZG, Milipied B, Lonjou C, et al. HLA-DRB1*01 associated with cutaneous hypersensitivity induced by nevirapine and efavirenz. AIDS. 2008;22(4):540-541.
    • (2008) AIDS , vol.22 , Issue.4 , pp. 540-541
    • Vitezica, Z.G.1    Milipied, B.2    Lonjou, C.3
  • 103
    • 0035085983 scopus 로고    scopus 로고
    • Peripheral neuropathy and antiretroviral drugs
    • Peripheral neuropathy and antiretroviral drugs. J Peripher Nerv Syst. 2001;6(1):14-20.
    • (2001) J Peripher Nerv Syst , vol.6 , Issue.1 , pp. 14-20
  • 104
    • 29144452191 scopus 로고    scopus 로고
    • Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: An adult AIDS clinical trials group study
    • Hulgan T, Haas DW, Haines JL, et al. Mitochondrial haplogroups and peripheral neuropathy during antiretroviral therapy: an adult AIDS clinical trials group study. AIDS. 2005;19(13):1341-1349.
    • (2005) AIDS , vol.19 , Issue.13 , pp. 1341-1349
    • Hulgan, T.1    Haas, D.W.2    Haines, J.L.3
  • 105
    • 38349127924 scopus 로고    scopus 로고
    • The mitochondrial pharmacogenomics of haplogroup T: MTND2*LHON4917G and antiretroviral therapy-associated peripheral neuropathy
    • Canter JA, Haas DW, Kallianpur AR, et al. The mitochondrial pharmacogenomics of haplogroup T: MTND2*LHON4917G and antiretroviral therapy-associated peripheral neuropathy. Pharmacogenomics J. 2008;8(1):71-77.
    • (2008) Pharmacogenomics J , vol.8 , Issue.1 , pp. 71-77
    • Canter, J.A.1    Haas, D.W.2    Kallianpur, A.R.3
  • 106
    • 33746211636 scopus 로고    scopus 로고
    • Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy
    • Kallianpur AR, Hulgan T, Canter JA, et al. Hemochromatosis (HFE) gene mutations and peripheral neuropathy during antiretroviral therapy. AIDS. 2006;20(11):1503-1513.
    • (2006) AIDS , vol.20 , Issue.11 , pp. 1503-1513
    • Kallianpur, A.R.1    Hulgan, T.2    Canter, J.A.3
  • 107
    • 78650948940 scopus 로고    scopus 로고
    • Tumour necrosis factor haplotypes associated with sensory neuropathy in Asian and Caucasian human immunodeficiency virus patients
    • Chew CS, Cherry CL, Imran D et al. Tumour necrosis factor haplotypes associated with sensory neuropathy in Asian and Caucasian human immunodeficiency virus patients. Tissue Antigens. 2011;77(2):126-130.
    • (2011) Tissue Antigens , vol.77 , Issue.2 , pp. 126-130
    • Chew, C.S.1    Cherry, C.L.2    Imran, D.3
  • 108
    • 39549113449 scopus 로고    scopus 로고
    • Cytokine genotype suggests a role for inflammation in nucleoside analog-associated sensory neuropathy (NRTI-SN) and predicts and individuals NRTI-SN risk
    • Cherry CL, Rosenow A, Affandi JS, et al. Cytokine genotype suggests a role for inflammation in nucleoside analog-associated sensory neuropathy (NRTI-SN) and predicts and individuals NRTI-SN risk. AIDS Res Hum Retroviruses. 2008;24(2):117-123.
    • (2008) AIDS Res Hum Retroviruses , vol.24 , Issue.2 , pp. 117-123
    • Cherry, C.L.1    Rosenow, A.2    Affandi, J.S.3
  • 109
    • 53849149000 scopus 로고    scopus 로고
    • Can we predict neuropathy risk before stavudine prescription in a resource-limited setting?
    • Afandi JS, Price P, Imran D, et al. Can we predict neuropathy risk before stavudine prescription in a resource-limited setting? AIDS Res Hum Retroviruses. 2008;24(1):1281-1284.
    • (2008) AIDS Res Hum Retroviruses , vol.24 , Issue.1 , pp. 1281-1284
    • Afandi, J.S.1    Price, P.2    Imran, D.3
  • 110
    • 34248212745 scopus 로고    scopus 로고
    • Novel mutation of human DNA polymerase gamma associated with mitochondrial toxicity induced by anti-HIV treatment
    • Yamanaka H, Gatanaga H, Kosalaraksa P, et al. Novel mutation of human DNA polymerase gamma associated with mitochondrial toxicity induced by anti-HIV treatment. J Infect Dis. 2007;195(10):1419-1425.
    • (2007) J Infect Dis , vol.195 , Issue.10 , pp. 1419-1425
    • Yamanaka, H.1    Gatanaga, H.2    Kosalaraksa, P.3
  • 111
    • 0037415033 scopus 로고    scopus 로고
    • Tumour necrosis factor-alpha gene 239G/A promoter polymorphism is associated with a more rapid onset of lipodystrophy
    • Nolan D, Moore C, Castley A, et al. Tumour necrosis factor-alpha gene 239G/A promoter polymorphism is associated with a more rapid onset of lipodystrophy. AIDS. 2003;17(1):121-123.
    • (2003) AIDS , vol.17 , Issue.1 , pp. 121-123
    • Nolan, D.1    Moore, C.2    Castley, A.3
  • 112
    • 0037131198 scopus 로고    scopus 로고
    • TNF-alpha promoter region gene polymoprhisms in HIV-positive patients with lipodystrophy
    • Maher B, Alfrevic A, Vilar FJ, et al. TNF-alpha promoter region gene polymoprhisms in HIV-positive patients with lipodystrophy. AIDS. 2003;16(15):2013-2018.
    • (2003) AIDS , vol.16 , Issue.15 , pp. 2013-2018
    • Maher, B.1    Alfrevic, A.2    Vilar, F.J.3
  • 113
    • 67649185305 scopus 로고    scopus 로고
    • Mitochondrial DNA haplogroups influence lipoatrophy after highly active antiretroviral therapy
    • Hendrickson SL, Kingsley LA, Ruiz-Pesini E, et al. Mitochondrial DNA haplogroups influence lipoatrophy after highly active antiretroviral therapy. J Acquir Immune Defic Syndr. 2009;51(2):111-116.
    • (2009) J Acquir Immune Defic Syndr , vol.51 , Issue.2 , pp. 111-116
    • Hendrickson, S.L.1    Kingsley, L.A.2    Ruiz-Pesini, E.3
  • 114
    • 40949123538 scopus 로고    scopus 로고
    • Hemochromatosis gene polymorphisms, mitochondrial haplogroups, and peripheral lipoatrophy during antiretroviral therapy
    • Hulgan T, Tebas P, Canter JA, et al. Hemochromatosis gene polymorphisms, mitochondrial haplogroups, and peripheral lipoatrophy during antiretroviral therapy. J Infect Dis. 2008;197(6):858-866.
    • (2008) J Infect Dis , vol.197 , Issue.6 , pp. 858-866
    • Hulgan, T.1    Tebas, P.2    Canter, J.A.3
  • 115
    • 40949114659 scopus 로고    scopus 로고
    • IL-1beta (+3954C/T) polymorphism could protect human immunodeficiency virus (HIV)-infected patients on highly active antiretroviral treatment (HAART) against lipodystrophic syndrome
    • Asensi V, Rego C, Montes AH, et al. IL-1beta (+3954C/T) polymorphism could protect human immunodeficiency virus (HIV)-infected patients on highly active antiretroviral treatment (HAART) against lipodystrophic syndrome. Gent Med. 2008;10(3):215-223.
    • (2008) Gent Med , vol.10 , Issue.3 , pp. 215-223
    • Asensi, V.1    Rego, C.2    Montes, A.H.3
  • 116
    • 52249097842 scopus 로고    scopus 로고
    • Genetic analysis implicates resistin in HIV lipodystrophy
    • Ranade K, Geese WJ, Noor M, et al. Genetic analysis implicates resistin in HIV lipodystrophy. AIDS. 2008;22(13):1561-1568.
    • (2008) AIDS , vol.22 , Issue.13 , pp. 1561-1568
    • Ranade, K.1    Geese, W.J.2    Noor, M.3
  • 117
    • 75749110161 scopus 로고    scopus 로고
    • Association between HLA-B*4001 and lipodystrophy among HIVinfected patients from Thailand who received a stavudine-containing antiretroviral regimen
    • Wangsomboonsiri W, Mahasirimongkol S, Chantarangsu S, et al. Association between HLA-B*4001 and lipodystrophy among HIVinfected patients from Thailand who received a stavudine-containing antiretroviral regimen. Clin Infect Dis. 2010;50(4):597-604.
    • (2010) Clin Infect Dis , vol.50 , Issue.4 , pp. 597-604
    • Wangsomboonsiri, W.1    Mahasirimongkol, S.2    Chantarangsu, S.3
  • 118
    • 34249984379 scopus 로고    scopus 로고
    • The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: The first 4 years
    • Nelson M, Katlama C, Montaner JS, et al. The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years. AIDS. 2007;21(10):1273-1281.
    • (2007) AIDS , vol.21 , Issue.10 , pp. 1273-1281
    • Nelson, M.1    Katlama, C.2    Montaner, J.S.3
  • 119
    • 77955786301 scopus 로고    scopus 로고
    • Systematic review and meta-analysis: Renal safety of tenofovir disoproxil fumarate in HIV-infected patients
    • Cooper RD, Wiebe N, Smith N, Keiser P, Naicker S, Tonelli M. Systematic review and meta-analysis: renal safety of tenofovir disoproxil fumarate in HIV-infected patients. Clin Infect Dis. 2010;51(5):496-505.
    • (2010) Clin Infect Dis , vol.51 , Issue.5 , pp. 496-505
    • Cooper, R.D.1    Wiebe, N.2    Smith, N.3    Keiser, P.4    Naicker, S.5    Tonelli, M.6
  • 120
    • 39349112711 scopus 로고    scopus 로고
    • Greater tenofovir-associated renal function decline with protease inhibitor-based versus nonnucleoside reverse-transcriptase inhibitor based therapy
    • Goicoechea M, Liu S, Best B, et al. Greater tenofovir-associated renal function decline with protease inhibitor-based versus nonnucleoside reverse-transcriptase inhibitor based therapy. Journal of Inf Dis. 2008;197(1):102-108.
    • (2008) Journal of Inf Dis , vol.197 , Issue.1 , pp. 102-108
    • Goicoechea, M.1    Liu, S.2    Best, B.3
  • 121
    • 38349171607 scopus 로고    scopus 로고
    • Clinical and genetic determinants of intracellular tenofovir diphosphate concentrations in HIV-infected patients
    • Kiser JJ, Aquilante CL, Anderson PL, King TM, Carten ML, Fletcher CV. Clinical and genetic determinants of intracellular tenofovir diphosphate concentrations in HIV-infected patients. Clin Pharmacol Ther. 2008;83(2):265-272.
    • (2008) Clin Pharmacol Ther , vol.83 , Issue.2 , pp. 265-272
    • Kiser, J.J.1    Aquilante, C.L.2    Anderson, P.L.3    King, T.M.4    Carten, M.L.5    Fletcher, C.V.6
  • 122
    • 33845226137 scopus 로고    scopus 로고
    • Association between ABBCC2 gene haplotypes and tenofovir-induced proximal tubulopathy
    • Izzedine H, Hulot JS, Villard E, et al. Association between ABBCC2 gene haplotypes and tenofovir-induced proximal tubulopathy. J Infect Dis. 2006;194(11):1481-1491.
    • (2006) J Infect Dis , vol.194 , Issue.11 , pp. 1481-1491
    • Izzedine, H.1    Hulot, J.S.2    Villard, E.3
  • 123
    • 66949119640 scopus 로고    scopus 로고
    • Predictors of kidney tubular dysfunction in HIV-infected patients treated with tenofovir: A pharmacogenetic study
    • Rodriguez-Novoa S, Labarga P, Soriano V, et al. Predictors of kidney tubular dysfunction in HIV-infected patients treated with tenofovir: a pharmacogenetic study. Clin Infect Dis. 2009;48(11): E108-E116.
    • (2009) Clin Infect Dis , vol.48 , Issue.11
    • Rodriguez-Novoa, S.1    Labarga, P.2    Soriano, V.3
  • 124
    • 79957933957 scopus 로고    scopus 로고
    • Genetic variants of ABCC10, a novel tenofovir transporter, are associated with kidney tubular dysfunction
    • Pushpakom SP, Liptrott NJ, Rodrigues-Novoa S, et al. Genetic variants of ABCC10, a novel tenofovir transporter, are associated with kidney tubular dysfunction. J Infect Dis. 2011;204(1):145-153.
    • (2011) J Infect Dis , vol.204 , Issue.1 , pp. 145-153
    • Pushpakom, S.P.1    Liptrott, N.J.2    Rodrigues-Novoa, S.3
  • 125
    • 0035940414 scopus 로고    scopus 로고
    • Mechanism of indinavir-induced hyperbilirubinemia
    • Zucker SC, Qin X, Rouster SC. Mechanism of indinavir-induced hyperbilirubinemia. Proc Natl Acad Sci U S A. 2001;98(22):12671-12676.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.22 , pp. 12671-12676
    • Zucker, S.C.1    Qin, X.2    Rouster, S.C.3
  • 126
    • 57749095660 scopus 로고    scopus 로고
    • Population pharmacokinetics of atazanavir in human immunodeficiency virus-infected patients
    • Solas C, Gagnieu MC, Ravaux I, et al. Population pharmacokinetics of atazanavir in human immunodeficiency virus-infected patients. Ther Drug Monit. 2008;30(6):670-673.
    • (2008) Ther Drug Monit , vol.30 , Issue.6 , pp. 670-673
    • Solas, C.1    Gagnieu, M.C.2    Ravaux, I.3
  • 127
    • 7944228403 scopus 로고    scopus 로고
    • Predictors of virological response to atazanavir in protease inhibitor exposed patients
    • Barrios A, Rendon AL, Gallego O, et al. Predictors of virological response to atazanavir in protease inhibitor exposed patients. HIV Clin Trials. 2004;5(4):201-205.
    • (2004) HIV Clin Trials , vol.5 , Issue.4 , pp. 201-205
    • Barrios, A.1    Rendon, A.L.2    Gallego, O.3
  • 128
    • 48949119333 scopus 로고    scopus 로고
    • Pharmacogenetics of Gilberts's syndrome
    • Strassburg CP. Pharmacogenetics of Gilberts's syndrome. Pharmacogenomics. 2008;9(6):703-715.
    • (2008) Pharmacogenomics , vol.9 , Issue.6 , pp. 703-715
    • Strassburg, C.P.1
  • 129
    • 25844446183 scopus 로고    scopus 로고
    • Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia
    • Rotger M, Taffe P, Bleiber G, et al. Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia. J Infect Dis. 2005;192(8):1381-1386.
    • (2005) J Infect Dis , vol.192 , Issue.8 , pp. 1381-1386
    • Rotger, M.1    Taffe, P.2    Bleiber, G.3
  • 130
    • 33845495422 scopus 로고    scopus 로고
    • Genetic factors influencing atazanavir plasma concentrations and the risk of severe hyperbilirubinemia
    • Rodriguez-Novoa S, Martin-Carbonero L, Barreiro P, et al. Genetic factors influencing atazanavir plasma concentrations and the risk of severe hyperbilirubinemia. AIDS. 2007;21(1):41-46.
    • (2007) AIDS , vol.21 , Issue.1 , pp. 41-46
    • Rodriguez-Novoa, S.1    Martin-Carbonero, L.2    Barreiro, P.3
  • 131
    • 77953775606 scopus 로고    scopus 로고
    • Genetic factors influencing severe atazanavir-associated hyperbilirbuinemia in a population with low UDP-glucuronosyltransferase 1A1*28 allele frequency
    • Park WB, Choe PG, Song KH, et al. Genetic factors influencing severe atazanavir-associated hyperbilirbuinemia in a population with low UDP-glucuronosyltransferase 1A1*28 allele frequency. Clin Infect Dis. 2010;51(1):101-106.
    • (2010) Clin Infect Dis , vol.51 , Issue.1 , pp. 101-106
    • Park, W.B.1    Choe, P.G.2    Song, K.H.3
  • 132
    • 34948845510 scopus 로고    scopus 로고
    • Treatment of an atazanavir associated grade 4 hyperbilirubinemia with efavirenz
    • Kummer O, Mossdorf E, Battegay M, et al. Treatment of an atazanavir associated grade 4 hyperbilirubinemia with efavirenz. Gut. 2007;56(10):1477-1478.
    • (2007) Gut , vol.56 , Issue.10 , pp. 1477-1478
    • Kummer, O.1    Mossdorf, E.2    Battegay, M.3
  • 133
    • 30144438738 scopus 로고    scopus 로고
    • Plasma levels of atazanavir and the risk of hyperbilirubinemia are predicted by the 3435 C--.T polymorphism at the multidrug resistance gene 1
    • Rodriguez-Novoa S, Barreiro P, Rendon A, et al. Plasma levels of atazanavir and the risk of hyperbilirubinemia are predicted by the 3435 C--.T polymorphism at the multidrug resistance gene 1. Clin Infect Dis. 2006;42(2):291-295.
    • (2006) Clin Infect Dis , vol.42 , Issue.2 , pp. 291-295
    • Rodriguez-Novoa, S.1    Barreiro, P.2    Rendon, A.3
  • 134
    • 79851482408 scopus 로고    scopus 로고
    • Association of pharmacogenetic markers with premature discontinuation of first-line anti HIV therapy: An observational cohort study
    • Lubomirov R, Colombo S, di Iulio J, et al. Association of pharmacogenetic markers with premature discontinuation of first-line anti HIV therapy: an observational cohort study. J Infect Dis. 2011;203(2):246-257.
    • (2011) J Infect Dis , vol.203 , Issue.2 , pp. 246-257
    • Lubomirov, R.1    Colombo, S.2    di Iulio, J.3
  • 135
    • 34547917168 scopus 로고    scopus 로고
    • Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy
    • Arnedo M, Tarffe P, Sahli R, et al. Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy. Pharmacogenet Genomics. 2007;17(9):755-764.
    • (2007) Pharmacogenet Genomics , vol.17 , Issue.9 , pp. 755-764
    • Arnedo, M.1    Tarffe, P.2    Sahli, R.3
  • 136
    • 77449143922 scopus 로고    scopus 로고
    • Contribution of genome-wide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: A longitudinal study
    • Rotger M, Bayard C, Taffe P, et al. Contribution of genome-wide significant single-nucleotide polymorphisms and antiretroviral therapy to dyslipidemia in HIV-infected individuals: a longitudinal study. Circ Cardiovasc Genet. 2009;2(6):621-628.
    • (2009) Circ Cardiovasc Genet , vol.2 , Issue.6 , pp. 621-628
    • Rotger, M.1    Bayard, C.2    Taffe, P.3
  • 137
    • 62449147005 scopus 로고    scopus 로고
    • Association of single-nucleotide polymorphism 3 and c.553G. T of APOA5 with hypertriglyceridemia after treatment with highly active antiretroviral therapy containing protease inhibitors in hiv-infected individuals in Taiwan
    • Chang SY, Ko WS, Kao JT, et al. Association of single-nucleotide polymorphism 3 and c.553G. T of APOA5 with hypertriglyceridemia after treatment with highly active antiretroviral therapy containing protease inhibitors in hiv-infected individuals in Taiwan. Clin Infect Dis. 2009;48(6):832-835.
    • (2009) Clin Infect Dis , vol.48 , Issue.6 , pp. 832-835
    • Chang, S.Y.1    Ko, W.S.2    Kao, J.T.3
  • 139
    • 20244375708 scopus 로고    scopus 로고
    • Modeling the influence of APOC3, APOE and TNF polymorphisms on the risk of antiretroviral therapyassociated lipid disorders
    • Tarr PE, Taffe P, Bleiber G, et al. Modeling the influence of APOC3, APOE and TNF polymorphisms on the risk of antiretroviral therapyassociated lipid disorders. J Infect Dis. 2005;191(9):1419-1426.
    • (2005) J Infect Dis , vol.191 , Issue.9 , pp. 1419-1426
    • Tarr, P.E.1    Taffe, P.2    Bleiber, G.3
  • 140
    • 77950344979 scopus 로고    scopus 로고
    • Dyslipidemia in HIV-infected individuals: From pharmacogenetics to pharmacogenomics
    • Tarr PE, Rotger M, Telenti A. Dyslipidemia in HIV-infected individuals: from pharmacogenetics to pharmacogenomics. Pharmacogenomics. 2010;11(4):587-594.
    • (2010) Pharmacogenomics , vol.11 , Issue.4 , pp. 587-594
    • Tarr, P.E.1    Rotger, M.2    Telenti, A.3
  • 141
    • 33749426630 scopus 로고    scopus 로고
    • Neuropsychiatric complications of antiretroviral therapy
    • Cespedes MS, Aberg JA. Neuropsychiatric complications of antiretroviral therapy. Drug Saf. 2006;29(10):865-874.
    • (2006) Drug Saf , vol.29 , Issue.10 , pp. 865-874
    • Cespedes, M.S.1    Aberg, J.A.2
  • 142
    • 61849109820 scopus 로고    scopus 로고
    • Absence of a relation between efavirenz plasma concentrations and toxicity-driven efavirenz discontinuations in the EuroSIDA study
    • Van Luiri M, Bannister WP, Mocroft A, et al. Absence of a relation between efavirenz plasma concentrations and toxicity-driven efavirenz discontinuations in the EuroSIDA study. Antivir Ther. 2009;14(1):75-83.
    • (2009) Antivir Ther , vol.14 , Issue.1 , pp. 75-83
    • van Luiri, M.1    Bannister, W.P.2    Mocroft, A.3
  • 143
    • 80051685348 scopus 로고    scopus 로고
    • Cytochrome P450 2B6(CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens
    • Wyen C, Hendra H, Siccardi M. Cytochrome P450 2B6(CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens. J Antimicrob Chemother. 2011;66(9):2092-2098.
    • (2011) J Antimicrob Chemother , vol.66 , Issue.9 , pp. 2092-2098
    • Wyen, C.1    Hendra, H.2    Siccardi, M.3
  • 144
    • 0037867653 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of nelfinavir and indinavir in treatment-naive HIV-1 infected individuals
    • Burger D, Hugen P, Reiss P, et al. Therapeutic drug monitoring of nelfinavir and indinavir in treatment-naive HIV-1 infected individuals. AIDS. 2003;17(8):1157-1165.
    • (2003) AIDS , vol.17 , Issue.8 , pp. 1157-1165
    • Burger, D.1    Hugen, P.2    Reiss, P.3
  • 145
    • 38949087231 scopus 로고    scopus 로고
    • The design and implementation of A5146, a prospective trial assessing the utility of therapeutic drug monitoring using an inhibitory quotient in antiretroviral-experienced HIV-infected patients
    • Demeter LM, Mukherjee AL, DiFrancesco R, et al. The design and implementation of A5146, a prospective trial assessing the utility of therapeutic drug monitoring using an inhibitory quotient in antiretroviral-experienced HIV-infected patients. HIV Clin Trials. 2008;9(1):61-72.
    • (2008) HIV Clin Trials , vol.9 , Issue.1 , pp. 61-72
    • Demeter, L.M.1    Mukherjee, A.L.2    Difrancesco, R.3
  • 146
    • 77955545884 scopus 로고    scopus 로고
    • Lopinavir tablet pharmacokinetics with an increased dose during pregnancy
    • Best BM, Stek AM, Mirochnick M, et al. Lopinavir tablet pharmacokinetics with an increased dose during pregnancy. J Acquir Immune Defic Syndr. 2010;54(4):381-388.
    • (2010) J Acquir Immune Defic Syndr , vol.54 , Issue.4 , pp. 381-388
    • Best, B.M.1    Stek, A.M.2    Mirochnick, M.3
  • 147
    • 10944246142 scopus 로고    scopus 로고
    • Pharmacokinetics of antiretrovirals in pregnant women
    • Mirochnick M, Capparelli E. Pharmacokinetics of antiretrovirals in pregnant women. Clin Pharmacokinet. 2004;43(15):1071-1087.
    • (2004) Clin Pharmacokinet , vol.43 , Issue.15 , pp. 1071-1087
    • Mirochnick, M.1    Capparelli, E.2
  • 148
    • 84856803234 scopus 로고    scopus 로고
    • Accessed October 11, 2011
    • http://www.hiv-pharmacogenomics.org/pdf/ref_tbl_pharmaco/HIV_Pharmacogenomics_reference_table.pdf. Accessed October 11, 2011.
  • 149
    • 77954365622 scopus 로고    scopus 로고
    • Pharmacogenetics of drug hypersensitivity
    • Phillips EJ, Mallal SA. Pharmacogenetics of drug hypersensitivity. Pharmacogenomics. 2010;11(7):973-987.
    • (2010) Pharmacogenomics , vol.11 , Issue.7 , pp. 973-987
    • Phillips, E.J.1    Mallal, S.A.2
  • 150
    • 70349292099 scopus 로고    scopus 로고
    • Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
    • Ge D, Fellay J, Thompson AJ, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature. 2009;461(7262):399-401.
    • (2009) Nature , vol.461 , Issue.7262 , pp. 399-401
    • Ge, D.1    Fellay, J.2    Thompson, A.J.3
  • 151
    • 70349533037 scopus 로고    scopus 로고
    • Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
    • Tanaka Y, Nishida N, Sugiyama M, et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Gent. 2009;41(10): 1105-1109.
    • (2009) Nat Gent , vol.41 , Issue.10 , pp. 1105-1109
    • Tanaka, Y.1    Nishida, N.2    Sugiyama, M.3
  • 152
    • 70349548852 scopus 로고    scopus 로고
    • IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
    • Suppiah V, Moldovan M, Ahlenstiel G, et al. IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat Genet. 2009;41(1):1100-1104.
    • (2009) Nat Genet , vol.41 , Issue.1 , pp. 1100-1104
    • Suppiah, V.1    Moldovan, M.2    Ahlenstiel, G.3
  • 154
    • 85027947842 scopus 로고    scopus 로고
    • Impact of IL28B polymorphisms on response to peginterferon and ribavirin in HIV-hepatitis C virus-co-infected patients with prior nonresponse or relapse
    • Labarga P, Barreiro P, Mira JA, et al. Impact of IL28B polymorphisms on response to peginterferon and ribavirin in HIV-hepatitis C virus-co-infected patients with prior nonresponse or relapse. AIDS. 2011;25(8):1131-1133.
    • (2011) AIDS , vol.25 , Issue.8 , pp. 1131-1133
    • Labarga, P.1    Barreiro, P.2    Mira, J.A.3


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