Novel mutation of human DNA polymerase γ associated with mitochondrial toxicity induced by anti-HIV treatment

Journal of Infectious Diseases

Volumn 195, Issue 10, 2007, Pages 1419-1425

  Yamanaka, Hikaru ^a,b   Gatanaga, Hiroyuki ^a   Kosalaraksa, Pope ^d   Matsuoka Aizawa, Saori ^a   Takahashi, Takao ^b   Kimura, Satoshi ^a,c   Oka, Shinichi ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c TOKYO TEISHIN HOSPITAL   (Japan)

^d KHON KAEN UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CYSTEINE; DNA DIRECTED DNA POLYMERASE GAMMA; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; MITOCHONDRIAL DNA; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE MUTATION; HEREDITY; HUMAN; HUMAN CELL; LACTIC ACIDOSIS; LYMPHOBLASTOID CELL LINE; MITOCHONDRIAL TOXICITY; PRIORITY JOURNAL; WILD TYPE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTI-HIV AGENTS; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; EXONS; FEMALE; HETEROZYGOTE DETECTION; HOMOZYGOTE; HUMANS; LACTATES; MALE; MITOCHONDRIA; MODELS, MOLECULAR; PEDIGREE; PROTEIN CONFORMATION; PROTEIN SUBUNITS; REFERENCE VALUES;

EID: 34248212745     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/513872     Document Type: Article

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