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Volumn 43, Issue 15, 2004, Pages 1071-1087

Pharmacokinetics of antiretrovirals in pregnant women

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR; AMPRENAVIR PHOSPHATE; ANTACID AGENT; ANTIRETROVIRUS AGENT; ATAZANAVIR; BETA LACTAM ANTIBIOTIC; DELAVIRDINE; DIAZEPAM; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; ENFUVIRTIDE; HYDROXYUREA; INDINAVIR; LAMIVUDINE; LOPINAVIR; LOPINAVIR PLUS RITONAVIR; NELFINAVIR; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SALICYLIC ACID DERIVATIVE; SAQUINAVIR; STAVUDINE; TENOFOVIR; THEOPHYLLINE; UNINDEXED DRUG; ZALCITABINE; ZIDOVUDINE;

EID: 10944246142     PISSN: 03125963     EISSN: None     Source Type: Journal    
DOI: 10.2165/00003088-200443150-00002     Document Type: Review
Times cited : (130)

References (118)
  • 2
    • 0028003766 scopus 로고
    • Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment
    • Connor EM, Sperling RS, Gelber R, et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. N Engl J Med 1994; 331: 1173-80
    • (1994) N Engl J Med , vol.331 , pp. 1173-1180
    • Connor, E.M.1    Sperling, R.S.2    Gelber, R.3
  • 3
    • 0036239507 scopus 로고    scopus 로고
    • Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission
    • Cooper ER, Charurat M, Mofenson L, et al. Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission. J Acquir Immune Defic Syndr 2002; 29: 484-94
    • (2002) J Acquir Immune Defic Syndr , vol.29 , pp. 484-494
    • Cooper, E.R.1    Charurat, M.2    Mofenson, L.3
  • 4
    • 0037055088 scopus 로고    scopus 로고
    • Addition of two-dose intrapartum/newborn nevirapine to standard antiretroviral therapy to reduce perinatal human immunodeficiency virus type-1 transmission: Peditric AIDS Clinical Trials Group 316
    • Dorenbaum A, Cunningham C, Gelber RD, et al. Addition of two-dose intrapartum/newborn nevirapine to standard antiretroviral therapy to reduce perinatal human immunodeficiency virus type-1 transmission: Peditric AIDS Clinical Trials Group 316. JAMA 2002; 288: 189-98
    • (2002) JAMA , vol.288 , pp. 189-198
    • Dorenbaum, A.1    Cunningham, C.2    Gelber, R.D.3
  • 6
    • 0033608845 scopus 로고    scopus 로고
    • Elective caesarian-section versus vaginal delivery in prevention of vertical HIV transmission: A randomised clinical trial
    • The European Mode of Delivery Collaboration. Elective caesarian-section versus vaginal delivery in prevention of vertical HIV transmission: a randomised clinical trial. Lancet 1999; 353: 1035-9
    • (1999) Lancet , vol.353 , pp. 1035-1039
  • 7
    • 0037071810 scopus 로고    scopus 로고
    • Management of human immunodeficiency virus infection in pregnancy
    • Watts HD. Management of human immunodeficiency virus infection in pregnancy. N Engl J Med 2002; 346: 1879-91
    • (2002) N Engl J Med , vol.346 , pp. 1879-1891
    • Watts, H.D.1
  • 8
    • 0034161410 scopus 로고    scopus 로고
    • Prevention of mother-to-child HIV transmission in resource-poor countries: Translating research into policy and practice
    • DeCock KM, Fowler MG, Mercier E, et al. Prevention of mother-to-child HIV transmission in resource-poor countries: translating research into policy and practice. JAMA 2000; 283: 1175-82
    • (2000) JAMA , vol.283 , pp. 1175-1182
    • DeCock, K.M.1    Fowler, M.G.2    Mercier, E.3
  • 10
    • 0030806572 scopus 로고    scopus 로고
    • Pharmacokinetic changes during pregnancy and their clinical relevance
    • Loebstein R, Lalkin A, Koren G. Pharmacokinetic changes during pregnancy and their clinical relevance. Clin Pharmacokinet 1997; 33: 328-43
    • (1997) Clin Pharmacokinet , vol.33 , pp. 328-343
    • Loebstein, R.1    Lalkin, A.2    Koren, G.3
  • 11
    • 0032447719 scopus 로고    scopus 로고
    • Low plasma concentrations of indinavir are related to virological treatment failure in HIV-1 infected patients on indinavir-containing triple therapy
    • Burger DM, Hoetelmans RMW, Hugen PWH, et al. Low plasma concentrations of indinavir are related to virological treatment failure in HIV-1 infected patients on indinavir-containing triple therapy. Antiviral Ther 1998; 3: 315-20
    • (1998) Antiviral Ther , vol.3 , pp. 315-320
    • Burger, D.M.1    Hoetelmans, R.M.W.2    Hugen, P.W.H.3
  • 13
    • 10944268052 scopus 로고    scopus 로고
    • High exposure to nevirapine is associated with a higher initial HIV-1 RNA clearance rate, a higher likelihood to reach undetectability, and prolonged suppression of HIV-1 replication
    • Oct 23-27; Lisbon
    • Veldkamp AI, Hoetelmans RMW, Beijnen JH, et al. High exposure to nevirapine is associated with a higher initial HIV-1 RNA clearance rate, a higher likelihood to reach undetectability, and prolonged suppression of HIV-1 replication [abstract 239]. 7th European Conference on Clinical Aspects and Treatment of HIV-Infection; 1999 Oct 23-27; Lisbon
    • (1999) 7th European Conference on Clinical Aspects and Treatment of HIV-Infection
    • Veldkamp, A.I.1    Hoetelmans, R.M.W.2    Beijnen, J.H.3
  • 14
    • 0036229917 scopus 로고    scopus 로고
    • CD4 response is correlated with peak plasma concentrations of indinavir in adults with undetectable human immunodeficiency virus ribonucleic acid
    • Anderson PL, Brundage RC, Kakuda TN, et al. CD4 response is correlated with peak plasma concentrations of indinavir in adults with undetectable human immunodeficiency virus ribonucleic acid. Clin Pharmacol Ther 2002; 71: 280-5
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 280-285
    • Anderson, P.L.1    Brundage, R.C.2    Kakuda, T.N.3
  • 15
    • 0030768366 scopus 로고    scopus 로고
    • Drug disposition in mother and foetus
    • Morgan DJ. Drug disposition in mother and foetus. Clin Exp Pharmacol Physiol 1997; 24: 869-73
    • (1997) Clin Exp Pharmacol Physiol , vol.24 , pp. 869-873
    • Morgan, D.J.1
  • 16
    • 0002565461 scopus 로고    scopus 로고
    • Drug distribution during fetal life
    • Polin RA, Fox WW, editors. Philadelphia (PA): WB Saunders Company
    • Wright LL, Catz CS. Drug distribution during fetal life. In: Polin RA, Fox WW, editors. Fetal and neonatal physiology. Philadelphia (PA): WB Saunders Company, 1998: 169
    • (1998) Fetal and Neonatal Physiology , pp. 169
    • Wright, L.L.1    Catz, C.S.2
  • 17
    • 0018848024 scopus 로고
    • Drug disposition and pharmacokinetics in the maternal-placental-fetal unit
    • Krauer B, Krauer F, Hytten FE. Drug disposition and pharmacokinetics in the maternal-placental-fetal unit. Pharmacol Ther 1980; 10: 301-28
    • (1980) Pharmacol Ther , vol.10 , pp. 301-328
    • Krauer, B.1    Krauer, F.2    Hytten, F.E.3
  • 18
    • 0020318252 scopus 로고
    • Plasma protein binding of drugs in pregnancy
    • Perucca E, Crema A. Plasma protein binding of drugs in pregnancy. Clin Pharmacokinet 1982; 7: 336-52
    • (1982) Clin Pharmacokinet , vol.7 , pp. 336-352
    • Perucca, E.1    Crema, A.2
  • 19
    • 0021182458 scopus 로고
    • 1-acid glycoprotein concentrations during pregnancy: An analysis of fetal-maternal pairs
    • 1-acid glycoprotein concentrations during pregnancy: an analysis of fetal-maternal pairs. Br J Obstet Gynaecol 1984; 91: 875-81
    • (1984) Br J Obstet Gynaecol , vol.91 , pp. 875-881
    • Krauer, B.1    Dayer, P.2    Anner, R.3
  • 20
    • 0025177225 scopus 로고
    • Characterization of theophylline binding to serum proteins in pregnant and non-pregnant women
    • Connelly TJ, Ruo TI, Frederiksen MC, et al. Characterization of theophylline binding to serum proteins in pregnant and non-pregnant women. Clin Pharm Ther 1990; 47: 68-72
    • (1990) Clin Pharm Ther , vol.47 , pp. 68-72
    • Connelly, T.J.1    Ruo, T.I.2    Frederiksen, M.C.3
  • 21
    • 0018953159 scopus 로고
    • Serum protein binding of drugs during and after pregnancy in humans
    • Dean M, Stock B, Patterson RJ, et al. Serum protein binding of drugs during and after pregnancy in humans. Clin Pharm Ther 1980; 28: 253-61
    • (1980) Clin Pharm Ther , vol.28 , pp. 253-261
    • Dean, M.1    Stock, B.2    Patterson, R.J.3
  • 22
    • 0028217648 scopus 로고
    • Review of β-lactam antibiotics in pregnancy: The need for adjustment of dosing schedules
    • Heikkila A, Erkkola R. Review of β-lactam antibiotics in pregnancy: the need for adjustment of dosing schedules. Clin Pharmacokinet 1994; 27: 49-62
    • (1994) Clin Pharmacokinet , vol.27 , pp. 49-62
    • Heikkila, A.1    Erkkola, R.2
  • 24
  • 25
    • 0017054375 scopus 로고
    • Interactions of various 19-nor steroids with human placental microsomal cytochrome P-450
    • Juchau MR, Mirkin DL, Zachariah PK. Interactions of various 19-nor steroids with human placental microsomal cytochrome P-450. Chem Biol Interact 1976; 15: 337-47
    • (1976) Chem Biol Interact , vol.15 , pp. 337-347
    • Juchau, M.R.1    Mirkin, D.L.2    Zachariah, P.K.3
  • 26
    • 0017752773 scopus 로고
    • Pharmacokinetics of ampicillin in pregnancy
    • Phillipson A. Pharmacokinetics of ampicillin in pregnancy. J Infect Dis 1982; 136: 370-6
    • (1982) J Infect Dis , vol.136 , pp. 370-376
    • Phillipson, A.1
  • 27
    • 0019156239 scopus 로고
    • Rapid gentamicin elimination in obstetric patients
    • Zaske DE, Cipolle RJ, Strate RG, et al. Rapid gentamicin elimination in obstetric patients. Obstet Gynecol 1980; 56: 559-64
    • (1980) Obstet Gynecol , vol.56 , pp. 559-564
    • Zaske, D.E.1    Cipolle, R.J.2    Strate, R.G.3
  • 28
    • 0034967832 scopus 로고    scopus 로고
    • The use of anticonvulsants during pregnancy
    • Yerby MS. The use of anticonvulsants during pregnancy. Semin Perinatol 2001; 25: 153-8
    • (2001) Semin Perinatol , vol.25 , pp. 153-158
    • Yerby, M.S.1
  • 29
    • 0034990838 scopus 로고    scopus 로고
    • Antidepressants during pregnancy and lactation: Defining exposure and treatment issues
    • Newport JD, Wilcox MM, Stowe ZN. Antidepressants during pregnancy and lactation: defining exposure and treatment issues. Semin Perinatol 2001; 25: 177-90
    • (2001) Semin Perinatol , vol.25 , pp. 177-190
    • Newport, J.D.1    Wilcox, M.M.2    Stowe, Z.N.3
  • 30
    • 0032922072 scopus 로고    scopus 로고
    • Pharmacokinetics during pregnancy: Evidence-based maternal dose formulation
    • Little B. Pharmacokinetics during pregnancy: evidence-based maternal dose formulation. Obstet Gynecol 1999; 93: 856-68
    • (1999) Obstet Gynecol , vol.93 , pp. 856-868
    • Little, B.1
  • 32
    • 0032955402 scopus 로고    scopus 로고
    • Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection
    • Barry M, Mulcahy F, Merry C, et al. Pharmacokinetics and potential interactions amongst antiretroviral agents used to treat patients with HIV infection. Clin Pharmacokinet 1999; 36: 289-304
    • (1999) Clin Pharmacokinet , vol.36 , pp. 289-304
    • Barry, M.1    Mulcahy, F.2    Merry, C.3
  • 33
    • 0024313295 scopus 로고
    • Clinical pharmacokinetics of zidovudine: An overview of current data
    • Collins JM, Unadkat JD. Clinical pharmacokinetics of zidovudine: an overview of current data. Clin Pharmacokinet 1989; 17: 1-9
    • (1989) Clin Pharmacokinet , vol.17 , pp. 1-9
    • Collins, J.M.1    Unadkat, J.D.2
  • 34
    • 0024318386 scopus 로고
    • Comparative pharmacokinetics of zidovudine (AZT) and its metabolite (GAZT) in healthy subjects and HIV seropositive patients
    • Singlas E, Pioger JC, Taburet AM, et al. Comparative pharmacokinetics of zidovudine (AZT) and its metabolite (GAZT) in healthy subjects and HIV seropositive patients. Eur J Clin Pharmacol 1989; 36: 639-40
    • (1989) Eur J Clin Pharmacol , vol.36 , pp. 639-640
    • Singlas, E.1    Pioger, J.C.2    Taburet, A.M.3
  • 35
    • 0023091771 scopus 로고
    • Plasma and cerebrospinal fluid pharmacokinetics of 3-azido-3- deoxythymidine: A novel pyrimidine analog with potential application for the treatment of patients with AIDS and related diseases
    • Klecker RW, Collins JM, Yarchoan R, et al. Plasma and cerebrospinal fluid pharmacokinetics of 3-azido-3-deoxythymidine: a novel pyrimidine analog with potential application for the treatment of patients with AIDS and related diseases. Clin Pharmacol Ther 1987; 41: 407-12
    • (1987) Clin Pharmacol Ther , vol.41 , pp. 407-412
    • Klecker, R.W.1    Collins, J.M.2    Yarchoan, R.3
  • 36
    • 0026031856 scopus 로고
    • Pharmacokinetic disposition of zidovudine during pregnancy
    • Watts HD, Brown ZA, Tartaglione T, et al. Pharmacokinetic disposition of zidovudine during pregnancy. J Infect Dis 1991; 163: 226-32
    • (1991) J Infect Dis , vol.163 , pp. 226-232
    • Watts, H.D.1    Brown, Z.A.2    Tartaglione, T.3
  • 37
    • 0026711120 scopus 로고
    • Zidovudine pharmacokinetics during pregnancy
    • Sperling RS, Roboz J, Dische R, et al. Zidovudine pharmacokinetics during pregnancy. Am J Perinatol 1992; 9: 247-9
    • (1992) Am J Perinatol , vol.9 , pp. 247-249
    • Sperling, R.S.1    Roboz, J.2    Dische, R.3
  • 38
    • 0027243089 scopus 로고
    • The pharmacokinetics and safety of zidovudine in the third trimester of pregnancy for women infected with human immunodeficiency virus and their infants
    • Phase I Acquired Immunodeficiency Syndrome Clinical Trials Group Study (protocol 082)
    • O'Sullivan MJ, Boyer PJ, Scott GB, et al. The pharmacokinetics and safety of zidovudine in the third trimester of pregnancy for women infected with human immunodeficiency virus and their infants. Phase I Acquired Immunodeficiency Syndrome Clinical Trials Group Study (protocol 082). Am J Obstet Gynecol 1993; 168: 1510-6
    • (1993) Am J Obstet Gynecol , vol.168 , pp. 1510-1516
    • O'Sullivan, M.J.1    Boyer, P.J.2    Scott, G.B.3
  • 39
    • 0031723646 scopus 로고    scopus 로고
    • Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring
    • Moodley J, Moodley K, Pillay K, et al. Pharmacokinetics and antiretroviral activity of lamivudine alone or when coadministered with zidovudine in human immunodeficiency virus type 1-infected pregnant women and their offspring. J Infect Dis 1998; 178: 1327-33
    • (1998) J Infect Dis , vol.178 , pp. 1327-1333
    • Moodley, J.1    Moodley, K.2    Pillay, K.3
  • 40
    • 0022996630 scopus 로고
    • Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the 5′-triphosphate with human immunodeficiency virus reverse transcriptase
    • Furman PA, Fyfe JA, St Clair MH, et al. Phosphorylation of 3′-azido-3′-deoxythymidine and selective interaction of the 5′-triphosphate with human immunodeficiency virus reverse transcriptase. Proc Natl Acad Sci U S A 1986; 83: 8333-7
    • (1986) Proc Natl Acad Sci U S A , vol.83 , pp. 8333-8337
    • Furman, P.A.1    Fyfe, J.A.2    St. Clair, M.H.3
  • 41
    • 0033933615 scopus 로고    scopus 로고
    • Pharmacokinetics of zidovudine phosphorylation in human immunodeficiency virus-positive Thai patients and healthy volunteers
    • Wattanagoon Y, Na Bangchang K, Hoggard PG, et al. Pharmacokinetics of zidovudine phosphorylation in human immunodeficiency virus-positive Thai patients and healthy volunteers. Antimicrob Agents Chemother 2000; 44: 1986-9
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 1986-1989
    • Wattanagoon, Y.1    Na Bangchang, K.2    Hoggard, P.G.3
  • 42
    • 0028232638 scopus 로고
    • Pharmacokinetics of zidovudine phosphorylation in peripheral blood mononuclear cells from patients infected with human immunodeficiency virus
    • Stretcher BN, Pesce AJ, Frame PT, et al. Pharmacokinetics of zidovudine phosphorylation in peripheral blood mononuclear cells from patients infected with human immunodeficiency virus. Antimicrob Agents Chemother 1994; 38: 1541-7
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 1541-1547
    • Stretcher, B.N.1    Pesce, A.J.2    Frame, P.T.3
  • 43
    • 0024405549 scopus 로고
    • Cellular pharmacology of 2′,3′-dideoxy-2′,3′- didehydrothymidine, a nucleoside analog active against human immunodeficiency virus
    • Ho HT, Hitchcock MJ. Cellular pharmacology of 2′,3′-dideoxy- 2′,3′-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus. Antimicrob Agents Chemother 1989; 33: 844-9
    • (1989) Antimicrob Agents Chemother , vol.33 , pp. 844-849
    • Ho, H.T.1    Hitchcock, M.J.2
  • 44
    • 0029768927 scopus 로고    scopus 로고
    • The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites
    • Barry M, Khoo S, Back DJ, et al. The effect of zidovudine dose on the formation of intracellular phosphorylated metabolites. AIDS 1996; 10: 1361-7
    • (1996) AIDS , vol.10 , pp. 1361-1367
    • Barry, M.1    Khoo, S.2    Back, D.J.3
  • 45
    • 0027364453 scopus 로고
    • Zidovudine response relationships in early human immunodeficiency virus infection
    • Sale M, Sheiner LB, Volberding P, et al. Zidovudine response relationships in early human immunodeficiency virus infection. Clin Pharmacol Ther 1993; 54: 556-66
    • (1993) Clin Pharmacol Ther , vol.54 , pp. 556-566
    • Sale, M.1    Sheiner, L.B.2    Volberding, P.3
  • 46
    • 0025872418 scopus 로고
    • Placental passage of azidothymidine (AZT) during the second trimester of pregnancy: A study by direct fetal blood sampling under ultrasound
    • Pons JC, Taburet AM, Singlas E, et al. Placental passage of azidothymidine (AZT) during the second trimester of pregnancy: a study by direct fetal blood sampling under ultrasound. Eur J Obstet Gynecol Reprod Biol 1991; 40: 229-31
    • (1991) Eur J Obstet Gynecol Reprod Biol , vol.40 , pp. 229-231
    • Pons, J.C.1    Taburet, A.M.2    Singlas, E.3
  • 47
    • 0025060258 scopus 로고
    • Azidothymidine (zidovudine) transport by the human placenta
    • Schenker S, Johnson RF, King TS, et al. Azidothymidine (zidovudine) transport by the human placenta. Am J Med Sci 1990; 299: 16-20
    • (1990) Am J Med Sci , vol.299 , pp. 16-20
    • Schenker, S.1    Johnson, R.F.2    King, T.S.3
  • 48
    • 0031004031 scopus 로고    scopus 로고
    • Transplacental Pharmacokinetics and fetal distribution of azidothymidine, its glucuronide, and phosphorylated metabolites in late-term rhesus macaques after maternal infusion
    • Patterson TA, Binienda ZK, Lipe GW, et al. Transplacental Pharmacokinetics and fetal distribution of azidothymidine, its glucuronide, and phosphorylated metabolites in late-term rhesus macaques after maternal infusion. Drug Metab Dispos 1997; 25: 453-9
    • (1997) Drug Metab Dispos , vol.25 , pp. 453-459
    • Patterson, T.A.1    Binienda, Z.K.2    Lipe, G.W.3
  • 49
    • 0027494689 scopus 로고
    • Nucleoside transport by perfused human placenta
    • Dancis J, Lee J, Mendoza S, et al. Nucleoside transport by perfused human placenta. Placenta 1993; 14: 547-54
    • (1993) Placenta , vol.14 , pp. 547-554
    • Dancis, J.1    Lee, J.2    Mendoza, S.3
  • 50
    • 0029119819 scopus 로고
    • Developmental pharmacology and toxicology of anti-HIV therapeutic agents: Dideoxynucleosides
    • Sandberg JA, Slikker W. Developmental pharmacology and toxicology of anti-HIV therapeutic agents: dideoxynucleosides. FASEB J 1995; 9: 1157-63
    • (1995) FASEB J , vol.9 , pp. 1157-1163
    • Sandberg, J.A.1    Slikker, W.2
  • 51
    • 0032710823 scopus 로고    scopus 로고
    • Systemic pharmacokinetics and cellular pharmacology of zidovudine in human immunodeficiency virus type 1-infected women and newborn infants
    • Rodman JH, Flynn PM, Robbins B, et al. Systemic pharmacokinetics and cellular pharmacology of zidovudine in human immunodeficiency virus type 1-infected women and newborn infants. J Infect Dis 1999; 180: 1844-50
    • (1999) J Infect Dis , vol.180 , pp. 1844-1850
    • Rodman, J.H.1    Flynn, P.M.2    Robbins, B.3
  • 52
    • 0033528520 scopus 로고    scopus 로고
    • Short-course zidovudine for perinatal HIV-1 transmission in Bangkok, Thailand: A randomized controlled trial
    • Shafer N, Chuachoowong R, Mock PA, et al. Short-course zidovudine for perinatal HIV-1 transmission in Bangkok, Thailand: a randomized controlled trial. Lancet 1999; 353: 773-80
    • (1999) Lancet , vol.353 , pp. 773-780
    • Shafer, N.1    Chuachoowong, R.2    Mock, P.A.3
  • 53
    • 0034610026 scopus 로고    scopus 로고
    • A trial of shortened zidovudine regimens to prevent mother-to-child transmission of human immunodeficiency virus type 1
    • Lallemant M, Gnazague J, Le Coeur S, et al. A trial of shortened zidovudine regimens to prevent mother-to-child transmission of human immunodeficiency virus type 1. N Engl J Med 2000; 343: 982-91
    • (2000) N Engl J Med , vol.343 , pp. 982-991
    • Lallemant, M.1    Gnazague, J.2    Le Coeur, S.3
  • 54
    • 0003293748 scopus 로고    scopus 로고
    • Systemic Pharmacokinetics (PK) of oral zidovudine (ZDV) given during labor to HIV-1 infected pregnant women during labor and delivery
    • Jan 30-Feb 2; San Francisco
    • Dorenbaum A, Rodman JH, Mirochnick M, et al. Systemic Pharmacokinetics (PK) of oral zidovudine (ZDV) given during labor to HIV-1 infected pregnant women during labor and delivery [abstract 660]. 7th Conference on Retroviruses and Opportunistic Infections; 2000 Jan 30-Feb 2; San Francisco
    • (2000) 7th Conference on Retroviruses and Opportunistic Infections
    • Dorenbaum, A.1    Rodman, J.H.2    Mirochnick, M.3
  • 55
    • 0034119034 scopus 로고    scopus 로고
    • Oral zidovudine during labor to prevent perinatal HIV transmission, Bangkok: Tolerance and zidovudine concentration in cord blood
    • Bhadrakom C, Simonds RJ, Mei JV, et al. Oral zidovudine during labor to prevent perinatal HIV transmission, Bangkok: tolerance and zidovudine concentration in cord blood. AIDS 2000; 14: 509-16
    • (2000) AIDS , vol.14 , pp. 509-516
    • Bhadrakom, C.1    Simonds, R.J.2    Mei, J.V.3
  • 56
    • 0002676479 scopus 로고    scopus 로고
    • The SAINT trial: Nevirapine (NVP) versus zidovudine (ZVD) + lamivudine (3TC) in prevention of peripartum HIV transmission
    • Jul 9-14; Durban 16
    • Moodley D. The SAINT trial: nevirapine (NVP) versus zidovudine (ZVD) + lamivudine (3TC) in prevention of peripartum HIV transmission [abstract]. Programme supplement of the XIII International AIDS Conference; 2000 Jul 9-14; Durban: 16
    • (2000) Programme Supplement of the XIII International AIDS Conference
    • Moodley, D.1
  • 57
    • 0030899204 scopus 로고    scopus 로고
    • Lamivudine: A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in the management of HIV infection
    • Perry CM, Faulds D. Lamivudine: a review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in the management of HIV infection. Drugs 1997; 53: 657-80
    • (1997) Drugs , vol.53 , pp. 657-680
    • Perry, C.M.1    Faulds, D.2
  • 58
    • 0029900659 scopus 로고    scopus 로고
    • Pharmacokinetics of lamivudine administered alone and with trimethoprim-sulfamethoxazole
    • Moore KH, Yuen GJ, Raasch RH, et al. Pharmacokinetics of lamivudine administered alone and with trimethoprim-sulfamethoxazole. Clin Pharmacol Ther 1996; 59: 550-8
    • (1996) Clin Pharmacol Ther , vol.59 , pp. 550-558
    • Moore, K.H.1    Yuen, G.J.2    Raasch, R.H.3
  • 59
    • 0001024860 scopus 로고    scopus 로고
    • The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1
    • Moore KH, Barren JE, Shaw S, et al. The pharmacokinetics of lamivudine phosphorylation in peripheral blood mononuclear cells from patients infected with HIV-1. AIDS 1999; 3: 2239-50
    • (1999) AIDS , vol.3 , pp. 2239-2250
    • Moore, K.H.1    Barren, J.E.2    Shaw, S.3
  • 60
    • 0031019520 scopus 로고    scopus 로고
    • The maternal-fetal transfer of lamivudine in the ex vivo human placenta
    • Bloom SL, Dias KM, Bawdon RE, et al. The maternal-fetal transfer of lamivudine in the ex vivo human placenta. Am J Obstet Gynecol 1997; 176: 291-3
    • (1997) Am J Obstet Gynecol , vol.176 , pp. 291-293
    • Bloom, S.L.1    Dias, K.M.2    Bawdon, R.E.3
  • 61
    • 0035124720 scopus 로고    scopus 로고
    • Maternal-fetal transfer and amniotic fluid accumulation of lamivudine in human immunodeficiency virus-infected pregnant women
    • Mandelbrot L, Peytavin G, Firtion G, et al. Maternal-fetal transfer and amniotic fluid accumulation of lamivudine in human immunodeficiency virus-infected pregnant women. Am J Obstet Gynecol 2001; 184 (2): 153-8
    • (2001) Am J Obstet Gynecol , vol.184 , Issue.2 , pp. 153-158
    • Mandelbrot, L.1    Peytavin, G.2    Firtion, G.3
  • 62
    • 0025763660 scopus 로고
    • Pharmacokinetics of didanosine in patients with acquired immunodeficiency syndrome or acquired immunodeficiency syndrome-related complex
    • Knupp CA, Shyu WC, Dolin R, et al. Pharmacokinetics of didanosine in patients with acquired immunodeficiency syndrome or acquired immunodeficiency syndrome-related complex. Clin Pharmacol Ther 1991; 49: 523-35
    • (1991) Clin Pharmacol Ther , vol.49 , pp. 523-535
    • Knupp, C.A.1    Shyu, W.C.2    Dolin, R.3
  • 63
    • 10544234617 scopus 로고    scopus 로고
    • Disposition of didanosine in HIV-seropositive patients with normal renal function or chronic renal failure: Influence of hemodialysis and continuous ambulatory peritoneal dialysis
    • Knupp CA, Hak LJ, Coakley DF, et al. Disposition of didanosine in HIV-seropositive patients with normal renal function or chronic renal failure: influence of hemodialysis and continuous ambulatory peritoneal dialysis. Clin Pharmacol Ther 1996; 60: 535-42
    • (1996) Clin Pharmacol Ther , vol.60 , pp. 535-542
    • Knupp, C.A.1    Hak, L.J.2    Coakley, D.F.3
  • 64
    • 0000483426 scopus 로고
    • Cellular pharmacology of the anti-HIV agent 2′,3′- dideoxyinosine
    • Ahluwalia G, Johnson MA, Fridland A, et al. Cellular pharmacology of the anti-HIV agent 2′,3′-dideoxyinosine [abstract]. Proc Am Acad Cancer Res 1988; 29: 349P
    • (1988) Proc Am Acad Cancer Res , vol.29
    • Ahluwalia, G.1    Johnson, M.A.2    Fridland, A.3
  • 65
    • 0032728821 scopus 로고    scopus 로고
    • Pharmacokinetics of didanosine in antepartum and postpartum human immunodeficiency virus: Infected pregnant women and their neonates: An AIDS Clinical Trials Group study
    • Wang Y, Livingston E, Patil S, et al. Pharmacokinetics of didanosine in antepartum and postpartum human immunodeficiency virus: infected pregnant women and their neonates: an AIDS Clinical Trials Group study. J Infect Dis 1999; 180: 1536-41
    • (1999) J Infect Dis , vol.180 , pp. 1536-1541
    • Wang, Y.1    Livingston, E.2    Patil, S.3
  • 66
    • 0028326579 scopus 로고
    • Transplacental pharmacokinetics of dideoxyinosine in pigtailed macaques
    • Pereira CM, Nosbisch C, Winter HR, et al. Transplacental pharmacokinetics of dideoxyinosine in pigtailed macaques. Antimicrob Agents Chemother 1994; 38: 781-6
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 781-786
    • Pereira, C.M.1    Nosbisch, C.2    Winter, H.R.3
  • 67
  • 68
    • 10944258340 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of d4T and 3TC in HIV-Infected pregnant women and their infants (PACTG 332)
    • Feb 10-14; Boston
    • Wade N, Unadkat J, Huang S, et al. Pharmacokinetics and safety of d4T and 3TC in HIV-Infected pregnant women and their infants (PACTG 332) [abstract 886]. Conference on Retroviruses and Opportunistic Infections; 2003 Feb 10-14; Boston
    • (2003) Conference on Retroviruses and Opportunistic Infections
    • Wade, N.1    Unadkat, J.2    Huang, S.3
  • 70
    • 0036199534 scopus 로고    scopus 로고
    • Acute onset lactic acidosis and pancreatitis in the third trimester of pregnancy in HIV-1 positive women taking antiretroviral medication
    • Sarner L, Fakoya A. Acute onset lactic acidosis and pancreatitis in the third trimester of pregnancy in HIV-1 positive women taking antiretroviral medication. Sexual Transm Infect 2002; 78: 58-9
    • (2002) Sexual Transm Infect , vol.78 , pp. 58-59
    • Sarner, L.1    Fakoya, A.2
  • 71
    • 0030982931 scopus 로고    scopus 로고
    • 1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity
    • Daluge SM, Good SS, Faletto MB, et al. 1592U89, a novel carbocyclic nucleoside analog with potent, selective anti-human immunodeficiency virus activity. Antimicrob Agents Chemother 1997; 41: 1082-93
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 1082-1093
    • Daluge, S.M.1    Good, S.S.2    Faletto, M.B.3
  • 72
    • 0033914965 scopus 로고    scopus 로고
    • Multiple-dose pharmacokinetics and pharmacodynamics of abacavir alone and in combination with zidovudine in human immunodeficiency virus-infected adults
    • McDowell JA, Lou Y, Symonds WS, et al. Multiple-dose pharmacokinetics and pharmacodynamics of abacavir alone and in combination with zidovudine in human immunodeficiency virus-infected adults. Antimicrob Agents Chemother 2000; 44: 2061-7
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2061-2067
    • McDowell, J.A.1    Lou, Y.2    Symonds, W.S.3
  • 73
    • 0037165904 scopus 로고    scopus 로고
    • Intracellular carbovir triphosphate levels in patients taking abacavir once a day
    • Harris M, Back D, Kewn S, et al. Intracellular carbovir triphosphate levels in patients taking abacavir once a day. AIDS 2002; 16: 1196-7
    • (2002) AIDS , vol.16 , pp. 1196-1197
    • Harris, M.1    Back, D.2    Kewn, S.3
  • 75
    • 0032985121 scopus 로고    scopus 로고
    • In vitro models to predict the in vivo mechanism, rate, and extent of placental transfer of dideoxynucleoside drugs against human immunodeficiency virus
    • Tuntland T, Odinecs A, Pereira CM, et al. In vitro models to predict the in vivo mechanism, rate, and extent of placental transfer of dideoxynucleoside drugs against human immunodeficiency virus. Am J Obstet Gynecol 1999; 180: 198-206
    • (1999) Am J Obstet Gynecol , vol.180 , pp. 198-206
    • Tuntland, T.1    Odinecs, A.2    Pereira, C.M.3
  • 76
    • 0032425415 scopus 로고    scopus 로고
    • The ex vivo human placental transfer of the anti-HIV nucleoside inhibitor abacavir and the protease inhibitor amprenavir
    • Bawdon RE. The ex vivo human placental transfer of the anti-HIV nucleoside inhibitor abacavir and the protease inhibitor amprenavir. Infect Dis Obstet Gynecol 1998; 6: 244-6
    • (1998) Infect Dis Obstet Gynecol , vol.6 , pp. 244-246
    • Bawdon, R.E.1
  • 77
    • 0027407285 scopus 로고
    • Pharmacokinetics of nevirapine: Initial single-rising-dose study in humans
    • Cheeseman SH, Hattox SE, McLaughlin MM, et al. Pharmacokinetics of nevirapine: initial single-rising-dose study in humans. Antimicrob Agents Chemother 1993; 37 (2): 178-82
    • (1993) Antimicrob Agents Chemother , vol.37 , Issue.2 , pp. 178-182
    • Cheeseman, S.H.1    Hattox, S.E.2    McLaughlin, M.M.3
  • 78
    • 0033384441 scopus 로고    scopus 로고
    • Single dose pharmacokinetics and bioavailability of nevirapine in healthy volunteers
    • Lamson MJ, Sabo JP, MacGregor TR, et al. Single dose pharmacokinetics and bioavailability of nevirapine in healthy volunteers. Biopharm Drug Dispos 1999; 20: 285-91
    • (1999) Biopharm Drug Dispos , vol.20 , pp. 285-291
    • Lamson, M.J.1    Sabo, J.P.2    MacGregor, T.R.3
  • 79
    • 10944265190 scopus 로고    scopus 로고
    • Effects of food or antacid on the bioavailability of nevirapine 200mg in 24 healthy volunteers [abstract]
    • Jul 7-12; Vancouver
    • Lamson MJ, Cort S, Sabo JP, et al. Effects of food or antacid on the bioavailability of nevirapine 200mg in 24 healthy volunteers [abstract]. 11th World Conference on AIDS; 1996 Jul 7-12; Vancouver
    • (1996) 11th World Conference on AIDS
    • Lamson, M.J.1    Cort, S.2    Sabo, J.P.3
  • 80
    • 0029761518 scopus 로고    scopus 로고
    • Nevirapine: A review of its development, pharmacological profile and potential for clinical use
    • Murphy RL, Montaner J. Nevirapine: a review of its development, pharmacological profile and potential for clinical use. Expert Opin Investig Drugs 1996; 5 (9): 1183-99
    • (1996) Expert Opin Investig Drugs , vol.5 , Issue.9 , pp. 1183-1199
    • Murphy, R.L.1    Montaner, J.2
  • 81
    • 0028900894 scopus 로고
    • Phase I/II evaluation of nevirapine alone and in combination with zidovudine for infection with human immunodeficiency virus
    • Cheeseman SH, Havlir D, McLaughlin MM, et al. Phase I/II evaluation of nevirapine alone and in combination with zidovudine for infection with human immunodeficiency virus. J Acquir Immune Defic Syndr Hum Retrovirol 1995; 8 (2): 141-51
    • (1995) J Acquir Immune Defic Syndr Hum Retrovirol , vol.8 , Issue.2 , pp. 141-151
    • Cheeseman, S.H.1    Havlir, D.2    McLaughlin, M.M.3
  • 82
    • 0028930117 scopus 로고
    • High dose nevirapine: Safety, pharmacokinetics and antiviral effect in patients with human immunodeficiency virus infection
    • Mar
    • Havlir D, Cheeseman SH, McLaughlin M, et al. High dose nevirapine: safety, pharmacokinetics and antiviral effect in patients with human immunodeficiency virus infection. J Infect Dis 1995 Mar; 171: 534-45
    • (1995) J Infect Dis , vol.171 , pp. 534-545
    • Havlir, D.1    Cheeseman, S.H.2    McLaughlin, M.3
  • 83
    • 0034679252 scopus 로고    scopus 로고
    • Pharmacological implications of prolonged in utero exposure to nevirapine
    • Taylor GP, Lyall E, Back D, et al. Pharmacological implications of prolonged in utero exposure to nevirapine. Lancet 2000; 355: 2134-5
    • (2000) Lancet , vol.355 , pp. 2134-2135
    • Taylor, G.P.1    Lyall, E.2    Back, D.3
  • 84
    • 10944266975 scopus 로고    scopus 로고
    • Steady state nevirapine pharmacokinetics during second and third trimester pregnancy and postpartum: PACTG 1022
    • Feb 8-11; San Francisco
    • Aweeka F, Lizak P, Frenkel L, et al. Steady state nevirapine pharmacokinetics during second and third trimester pregnancy and postpartum: PACTG 1022. 11th Conference on Retroviruses and Opportunistic Infections; 2004 Feb 8-11; San Francisco
    • (2004) 11th Conference on Retroviruses and Opportunistic Infections
    • Aweeka, F.1    Lizak, P.2    Frenkel, L.3
  • 85
    • 3042814812 scopus 로고    scopus 로고
    • Maternal toxicity with continuous nevirapine in pregnancy: Results from PACTG 1022
    • Hitti J, Frenkel L, Stek A, et al. Maternal toxicity with continuous nevirapine in pregnancy: results from PACTG 1022. J AIDS 2004; 36: 772-6
    • (2004) J AIDS , vol.36 , pp. 772-776
    • Hitti, J.1    Frenkel, L.2    Stek, A.3
  • 86
    • 0034887473 scopus 로고    scopus 로고
    • Nevirapine pharmacokinetics in pregnant women and in their infants following in utero exposure
    • Mirochnick M, Siminski S, Fenton T, et al. Nevirapine pharmacokinetics in pregnant women and in their infants following in utero exposure. Pediatr Infect Dis J 2001; 20: 803-5
    • (2001) Pediatr Infect Dis J , vol.20 , pp. 803-805
    • Mirochnick, M.1    Siminski, S.2    Fenton, T.3
  • 87
    • 17344368990 scopus 로고    scopus 로고
    • Pharmacokinetics of nevirapine in human immunodeficiency virus type-1 infected pregnant women and their neonates
    • Aug
    • Mirochnick M, Fenton T, Gagnier P, et al. Pharmacokinetics of nevirapine in human immunodeficiency virus type-1 infected pregnant women and their neonates. J Infect Dis 1998 Aug; 178: 368-74
    • (1998) J Infect Dis , vol.178 , pp. 368-374
    • Mirochnick, M.1    Fenton, T.2    Gagnier, P.3
  • 88
    • 0033545463 scopus 로고    scopus 로고
    • A phase I study of the safety and pharmacokinetics of nevirapine in HIV-1 infected pregnant Ugandan women and their neonates
    • Musoke P, Quay L, Bagenda D, et al. A phase I study of the safety and pharmacokinetics of nevirapine in HIV-1 infected pregnant Ugandan women and their neonates. AIDS 1999; 13 (4): 479-86
    • (1999) AIDS , vol.13 , Issue.4 , pp. 479-486
    • Musoke, P.1    Quay, L.2    Bagenda, D.3
  • 89
    • 0033523454 scopus 로고    scopus 로고
    • Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-infant transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial
    • Guay L, Musoke P, Fleming T, et al. Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-infant transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial. Lancet 1999; 354: 795-802
    • (1999) Lancet , vol.354 , pp. 795-802
    • Guay, L.1    Musoke, P.2    Fleming, T.3
  • 91
    • 0035913939 scopus 로고    scopus 로고
    • Selection and fading of resistance mutations in Ugandan women and infants receiving nevirapine prophylaxis to prevent HIV-1 vertical transmission (HIVNET-012)
    • Eshleman SH, Mracna M, Guay L, et al. Selection and fading of resistance mutations in Ugandan women and infants receiving nevirapine prophylaxis to prevent HIV-1 vertical transmission (HIVNET-012). AIDS 2001; 15: 1951-7
    • (2001) AIDS , vol.15 , pp. 1951-1957
    • Eshleman, S.H.1    Mracna, M.2    Guay, L.3
  • 93
    • 4244187226 scopus 로고    scopus 로고
    • Wilmington (DE): Dupont Pharmaceuticals Company
    • Sustiva package insert. Wilmington (DE): Dupont Pharmaceuticals Company, 2000
    • (2000) Sustiva Package Insert
  • 94
    • 0037169263 scopus 로고    scopus 로고
    • Myelomeningocele in a child with intrauterine exposure to efavirenz
    • Fundaro C, Genovese O, Rendeli C, et al. Myelomeningocele in a child with intrauterine exposure to efavirenz. AIDS 2002; 16 (2): 299-300
    • (2002) AIDS , vol.16 , Issue.2 , pp. 299-300
    • Fundaro, C.1    Genovese, O.2    Rendeli, C.3
  • 95
    • 0344513445 scopus 로고    scopus 로고
    • La Jolla (CA): Agouron Pharmaceuticals
    • Rescriptor package insert. La Jolla (CA): Agouron Pharmaceuticals, 2001
    • (2001) Rescriptor Package Insert
  • 97
    • 0030895312 scopus 로고    scopus 로고
    • Protease inhibitors in patients with HIV disease: Clinically important pharmacokinetic considerations
    • Barry M, Gibbons S, Back D, et al. Protease inhibitors in patients with HIV disease: clinically important pharmacokinetic considerations. Clin Pharmacokinet 1997; 32: 194-209
    • (1997) Clin Pharmacokinet , vol.32 , pp. 194-209
    • Barry, M.1    Gibbons, S.2    Back, D.3
  • 98
    • 0036375115 scopus 로고    scopus 로고
    • Concentrations of protease inhibitors in cord blood following in utero exposure
    • Mirochnick M, Dorenbaum A, Holland D, et al. Concentrations of protease inhibitors in cord blood following in utero exposure. Pediatr Infect Dis J 2002; 9: 835-9
    • (2002) Pediatr Infect Dis J , vol.9 , pp. 835-839
    • Mirochnick, M.1    Dorenbaum, A.2    Holland, D.3
  • 99
    • 0037066372 scopus 로고    scopus 로고
    • Transplacental passage of protease inhibitors at delivery
    • Marzolini C, Rudin C, Decosterd LA, et al. Transplacental passage of protease inhibitors at delivery. AIDS 2002; 16:889-93
    • (2002) AIDS , vol.16 , pp. 889-893
    • Marzolini, C.1    Rudin, C.2    Decosterd, L.A.3
  • 100
    • 0004226350 scopus 로고    scopus 로고
    • La Jolla (CA): Agouron Pharmaceuticals
    • Viracept package insert. La Jolla (CA): Agouron Pharmaceuticals, 2001
    • (2001) Viracept Package Insert
  • 101
    • 0032895879 scopus 로고    scopus 로고
    • Nelfinavir mesylate: A protease inhibitor
    • Pai VB. Nahata MC. Nelfinavir mesylate: a protease inhibitor. Ann Pharmacother 1999; 33: 325-39
    • (1999) Ann Pharmacother , vol.33 , pp. 325-339
    • Pai, V.B.1    Nahata, M.C.2
  • 102
    • 0003279914 scopus 로고    scopus 로고
    • PACTG 353: A phase I study of safety, pharmacokinetics and antiviral activity of combination nelfinavir (NFV), ZDV and 3TC in HIV infected pregnant women and their infants
    • Jan 30-Feb 2; San Francisco
    • Bryson YJ, Stek A, Mirochnick M, et al. PACTG 353: a phase I study of safety, pharmacokinetics and antiviral activity of combination nelfinavir (NFV), ZDV and 3TC in HIV infected pregnant women and their infants. 7th Conference on Retroviruses and Opportunistic Infections; 2000 Jan 30-Feb 2; San Francisco
    • (2000) 7th Conference on Retroviruses and Opportunistic Infections
    • Bryson, Y.J.1    Stek, A.2    Mirochnick, M.3
  • 103
    • 4444238839 scopus 로고    scopus 로고
    • Pharmacokinetics, antiviral activity and safety of nelfinavir (NFV) with ZDV/3TC in pregnant HIV-Infected women and their infants: PACTG 353 cohort 2
    • Feb 24-28; Seattle
    • Bryson YJ, Stek A, Mirochnick M, et al. Pharmacokinetics, antiviral activity and safety of nelfinavir (NFV) with ZDV/3TC in pregnant HIV-Infected women and their infants: PACTG 353 cohort 2 [abstract 795]. 9th Conference on Retroviruses and Opportunistic Infections; 2002 Feb 24-28; Seattle
    • (2002) 9th Conference on Retroviruses and Opportunistic Infections
    • Bryson, Y.J.1    Stek, A.2    Mirochnick, M.3
  • 104
    • 10944242164 scopus 로고    scopus 로고
    • Pharmacokinetics (PK) of nelfinavir (NFV) and its M8 metabolite in pregnant HIV-Infected women and their infants: PACTG 353
    • May 3-6; Seattle
    • Mirochnick M, Bryson Y, Stek A, et al. Pharmacokinetics (PK) of nelfinavir (NFV) and its M8 metabolite in pregnant HIV-Infected women and their infants: PACTG 353. Pediatric Academic Societies Meeting; 2003 May 3-6; Seattle
    • (2003) Pediatric Academic Societies Meeting
    • Mirochnick, M.1    Bryson, Y.2    Stek, A.3
  • 105
    • 0034034618 scopus 로고    scopus 로고
    • Pharmacokinetics of indinavir in HIV-positive pregnant women
    • Hayashi S, Beckerman K, Homma M, et al. Pharmacokinetics of indinavir in HIV-positive pregnant women. AIDS 2000; 14: 1061-2
    • (2000) AIDS , vol.14 , pp. 1061-1062
    • Hayashi, S.1    Beckerman, K.2    Homma, M.3
  • 106
    • 10944273248 scopus 로고    scopus 로고
    • PACTG 358: Safety, Pharmacokinetics and antiretroviral activity of indinavir, zidovudine (ZDV) and lamuvidine (3TC) in HIV-1 seropositive pregnant women and infants [abstract 447]
    • Sep 1-5; Montreal
    • Wara D, Tuomala R, Bryson Y, et al. PACTG 358: safety, Pharmacokinetics and antiretroviral activity of indinavir, zidovudine (ZDV) and lamuvidine (3TC) in HIV-1 seropositive pregnant women and infants [abstract 447]. 2nd Conference on Global Strategies for the Prevention of HIV Transmission from Mothers to Infants; 1999 Sep 1-5; Montreal
    • (1999) 2nd Conference on Global Strategies for the Prevention of HIV Transmission from Mothers to Infants
    • Wara, D.1    Tuomala, R.2    Bryson, Y.3
  • 107
    • 10944240752 scopus 로고    scopus 로고
    • Nutley (NJ): Roche Pharmaceuticals
    • Inverase package insert. Nutley (NJ): Roche Pharmaceuticals, 2000
    • (2000) Inverase Package Insert
  • 108
    • 2142788927 scopus 로고    scopus 로고
    • Nutley (NJ): Roche Pharmaceuticals
    • Fortovase package insert. Nutley (NJ): Roche Pharmaceuticals, 2000
    • (2000) Fortovase Package Insert
  • 109
    • 0035111994 scopus 로고    scopus 로고
    • Elevated alpha-1-acid glycoprotein reduces the volume of distribution and systemic clearance of saquinavir
    • Holladay JW, Dewey MJ, Michniak BB, et al. Elevated alpha-1-acid glycoprotein reduces the volume of distribution and systemic clearance of saquinavir. Drug Metab Dispos 2001; 29: 299-303
    • (2001) Drug Metab Dispos , vol.29 , pp. 299-303
    • Holladay, J.W.1    Dewey, M.J.2    Michniak, B.B.3
  • 110
    • 0035211283 scopus 로고    scopus 로고
    • Pharmacokinetics of saquinavir-SGC in HIV-Infected pregnant women
    • Acosta EP, Zorrilla C, Van Dyke R, et al. Pharmacokinetics of saquinavir-SGC in HIV-Infected pregnant women. HIV Clin Trials 2001; 2: 460-5
    • (2001) HIV Clin Trials , vol.2 , pp. 460-465
    • Acosta, E.P.1    Zorrilla, C.2    Van Dyke, R.3
  • 111
    • 0036683493 scopus 로고    scopus 로고
    • Safety and efficacy of saquinavir soft-gelatin capsules + zidovudine + optional lamivudine in pregnancy and prevention of vertical HIV transmission
    • Vithayasai V, Moyle GJ, Supajatura V, et al. Safety and efficacy of saquinavir soft-gelatin capsules + zidovudine + optional lamivudine in pregnancy and prevention of vertical HIV transmission. J Acquir Immune Defic Syndr 2002; 30: 410-2
    • (2002) J Acquir Immune Defic Syndr , vol.30 , pp. 410-412
    • Vithayasai, V.1    Moyle, G.J.2    Supajatura, V.3
  • 112
    • 9144268274 scopus 로고    scopus 로고
    • Pharmacokinetics of saquinavir plus low-dose ritonavir in human immunodeficiency virus-infected pregnant women
    • Acosta EP, Bardeguez A, Zorrilla CD, et al. Pharmacokinetics of saquinavir plus low-dose ritonavir in human immunodeficiency virus-infected pregnant women. Antimicrob Agents Chemother 2004; 48: 430-6
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 430-436
    • Acosta, E.P.1    Bardeguez, A.2    Zorrilla, C.D.3
  • 113
    • 0042498403 scopus 로고    scopus 로고
    • Pharmacokinetic and virologic response to ritonavir (RTV) in combination with zidovudine (ZDV) and lamivudine (3TC) in HIV-1-infected pregnant women and their infants [abstract 794]
    • Feb 24-28; Seattle
    • Scott G, Rodman J, Scott W, et al. Pharmacokinetic and virologic response to ritonavir (RTV) in combination with zidovudine (ZDV) and lamivudine (3TC) in HIV-1-infected pregnant women and their infants [abstract 794]. 9th Conference on Retroviruses and Opportunistic Infections; 2002 Feb 24-28; Seattle
    • (2002) 9th Conference on Retroviruses and Opportunistic Infections
    • Scott, G.1    Rodman, J.2    Scott, W.3
  • 114
    • 0003539832 scopus 로고    scopus 로고
    • Abbott Park (IL): Abbott Laboratories
    • Norvir package insert. Abbott Park (IL): Abbott Laboratories, 2000
    • (2000) Norvir Package Insert
  • 115
    • 0942297950 scopus 로고    scopus 로고
    • Lopinavir protein binding in vivo through the 12-hour dosing interval
    • Boffito M, Hoggard PG, Lindup WE, et al. Lopinavir protein binding in vivo through the 12-hour dosing interval. Ther Drug Monit 2004; 26: 35-9
    • (2004) Ther Drug Monit , vol.26 , pp. 35-39
    • Boffito, M.1    Hoggard, P.G.2    Lindup, W.E.3
  • 116
    • 10944238567 scopus 로고    scopus 로고
    • Reduced lopinavir exposure during pregnancy: Preliminary pharmacokinetic results from PACTG 1026
    • Jul 11-16; Bangkok
    • Stek A, Mirochnick M, Capparelli E, et al. Reduced lopinavir exposure during pregnancy: preliminary pharmacokinetic results from PACTG 1026. XV International AIDS Conference; 2004 Jul 11-16; Bangkok
    • (2004) XV International AIDS Conference
    • Stek, A.1    Mirochnick, M.2    Capparelli, E.3
  • 117
    • 10944234841 scopus 로고    scopus 로고
    • Bloomington (MN): MGI Pharma Inc
    • Mylocel package insert. Bloomington (MN): MGI Pharma Inc, 2001
    • (2001) Mylocel Package Insert


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