-
1
-
-
77953896432
-
Cell signaling by receptor tyrosine kinases
-
Lemmon MA, Schlessinger J, (2010) Cell signaling by receptor tyrosine kinases. Cell 141 (7): 1117-1134.
-
(2010)
Cell
, vol.141
, Issue.7
, pp. 1117-1134
-
-
Lemmon, M.A.1
Schlessinger, J.2
-
2
-
-
0023947367
-
Leukocytes express a novel gene encoding a putative transmembrane protein-kinase devoid of an extracellular domain
-
Ben-Neriah Y, Bauskin AR, (1988) Leukocytes express a novel gene encoding a putative transmembrane protein-kinase devoid of an extracellular domain. Nature 333 (6174): 672-676.
-
(1988)
Nature
, vol.333
, Issue.6174
, pp. 672-676
-
-
Ben-Neriah, Y.1
Bauskin, A.R.2
-
3
-
-
0025314723
-
The ltk receptor tyrosine kinase is expressed in pre-B lymphocytes and cerebral neurons and uses a non-AUG translational initiator
-
Bernards A, de la Monte SM, (1990) The ltk receptor tyrosine kinase is expressed in pre-B lymphocytes and cerebral neurons and uses a non-AUG translational initiator. Embo J 9 (7): 2279-2287.
-
(1990)
Embo J
, vol.9
, Issue.7
, pp. 2279-2287
-
-
Bernards, A.1
de la Monte, S.M.2
-
4
-
-
0027193449
-
Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein
-
Toyoshima H, Kozutsumi H, Maru Y, Hagiwara K, Furuya A, et al. (1993) Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein. Proc Natl Acad Sci U S A 90 (12): 5404-5408.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, Issue.12
, pp. 5404-5408
-
-
Toyoshima, H.1
Kozutsumi, H.2
Maru, Y.3
Hagiwara, K.4
Furuya, A.5
-
5
-
-
0025216766
-
Human ltk: gene structure and preferential expression in human leukemic cells
-
Maru Y, Hirai H, Takaku F, (1990) Human ltk: gene structure and preferential expression in human leukemic cells. Oncogene Res 5 (3): 199-204.
-
(1990)
Oncogene Res
, vol.5
, Issue.3
, pp. 199-204
-
-
Maru, Y.1
Hirai, H.2
Takaku, F.3
-
6
-
-
0027317127
-
Identification of the human ltk gene product in placenta and hematopoietic cell lines
-
Kozutsumi H, Toyoshima H, Hagiwara K, Furuya A, Mioh H, et al. (1993) Identification of the human ltk gene product in placenta and hematopoietic cell lines. Biochem Biophys Res Commun 190 (2): 674-679.
-
(1993)
Biochem Biophys Res Commun
, vol.190
, Issue.2
, pp. 674-679
-
-
Kozutsumi, H.1
Toyoshima, H.2
Hagiwara, K.3
Furuya, A.4
Mioh, H.5
-
7
-
-
0031008896
-
ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK)
-
Morris SW, Naeve C, Mathew P, James PL, Kirstein MN, et al. (1997) ALK, the chromosome 2 gene locus altered by the t(2;5) in non-Hodgkin's lymphoma, encodes a novel neural receptor tyrosine kinase that is highly related to leukocyte tyrosine kinase (LTK). Oncogene 14 (18): 2175-2188.
-
(1997)
Oncogene
, vol.14
, Issue.18
, pp. 2175-2188
-
-
Morris, S.W.1
Naeve, C.2
Mathew, P.3
James, P.L.4
Kirstein, M.N.5
-
8
-
-
0025879519
-
The ltk gene encodes a novel receptor-type protein tyrosine kinase
-
Krolewski JJ, Dalla-Favera R, (1991) The ltk gene encodes a novel receptor-type protein tyrosine kinase. Embo J 10 (10): 2911-2919.
-
(1991)
Embo J
, vol.10
, Issue.10
, pp. 2911-2919
-
-
Krolewski, J.J.1
Dalla-Favera, R.2
-
9
-
-
0029125843
-
An epidermal growth factor receptor-leukocyte tyrosine kinase chimeric receptor generates ligand-dependent growth signals through the Ras signaling pathway
-
Ueno H, Hirano N, Kozutsumi H, Sasaki K, Tanaka T, et al. (1995) An epidermal growth factor receptor-leukocyte tyrosine kinase chimeric receptor generates ligand-dependent growth signals through the Ras signaling pathway. J Biol Chem 270 (34): 20135-20142.
-
(1995)
J Biol Chem
, vol.270
, Issue.34
, pp. 20135-20142
-
-
Ueno, H.1
Hirano, N.2
Kozutsumi, H.3
Sasaki, K.4
Tanaka, T.5
-
10
-
-
0033166257
-
Heart-specific activation of LTK results in cardiac hypertrophy, cardiomyocyte degeneration and gene reprogramming in transgenic mice
-
Honda H, Harada K, Komuro I, Terasaki F, Ueno H, et al. (1999) Heart-specific activation of LTK results in cardiac hypertrophy, cardiomyocyte degeneration and gene reprogramming in transgenic mice. Oncogene 18 (26): 3821-3830.
-
(1999)
Oncogene
, vol.18
, Issue.26
, pp. 3821-3830
-
-
Honda, H.1
Harada, K.2
Komuro, I.3
Terasaki, F.4
Ueno, H.5
-
11
-
-
41949111544
-
Leukocyte tyrosine kinase functions in pigment cell development
-
Lopes SS, Yang X, Muller J, Carney TJ, McAdow AR, et al. (2008) Leukocyte tyrosine kinase functions in pigment cell development. PLoS Genet 4 (3): e1000026.
-
(2008)
PLoS Genet
, vol.4
, Issue.3
-
-
Lopes, S.S.1
Yang, X.2
Muller, J.3
Carney, T.J.4
McAdow, A.R.5
-
12
-
-
56749131026
-
Expression of a chimeric CSF1R-LTK mediates ligand-dependent neurite outgrowth
-
Yamada S, Nomura T, Takano K, Fujita S, Miyake M, et al. (2008) Expression of a chimeric CSF1R-LTK mediates ligand-dependent neurite outgrowth. Neuroreport 19 (17): 1733-1738.
-
(2008)
Neuroreport
, vol.19
, Issue.17
, pp. 1733-1738
-
-
Yamada, S.1
Nomura, T.2
Takano, K.3
Fujita, S.4
Miyake, M.5
-
13
-
-
0029911031
-
Growth and survival signals transmitted via two distinct NPXY motifs within leukocyte tyrosine kinase, an insulin receptor-related tyrosine kinase
-
Ueno H, Sasaki K, Kozutsumi H, Miyagawa K, Mitani K, et al. (1996) Growth and survival signals transmitted via two distinct NPXY motifs within leukocyte tyrosine kinase, an insulin receptor-related tyrosine kinase. J Biol Chem 271 (44): 27707-27714.
-
(1996)
J Biol Chem
, vol.271
, Issue.44
, pp. 27707-27714
-
-
Ueno, H.1
Sasaki, K.2
Kozutsumi, H.3
Miyagawa, K.4
Mitani, K.5
-
14
-
-
0030850717
-
The phosphatidylinositol 3′ kinase pathway is required for the survival signal of leukocyte tyrosine kinase
-
Ueno H, Honda H, Nakamoto T, Yamagata T, Sasaki K, et al. (1997) The phosphatidylinositol 3′ kinase pathway is required for the survival signal of leukocyte tyrosine kinase. Oncogene 14 (25): 3067-3072.
-
(1997)
Oncogene
, vol.14
, Issue.25
, pp. 3067-3072
-
-
Ueno, H.1
Honda, H.2
Nakamoto, T.3
Yamagata, T.4
Sasaki, K.5
-
15
-
-
0028030798
-
Human ltk receptor tyrosine kinase binds to PLC-gamma 1, PI3-K, GAP and Raf-1 in vivo
-
Kozutsumi H, Toyoshima H, Hagiwara K, Yazaki Y, Hirai H, (1994) Human ltk receptor tyrosine kinase binds to PLC-gamma 1, PI3-K, GAP and Raf-1 in vivo. Oncogene 9 (10): 2991-2998.
-
(1994)
Oncogene
, vol.9
, Issue.10
, pp. 2991-2998
-
-
Kozutsumi, H.1
Toyoshima, H.2
Hagiwara, K.3
Yazaki, Y.4
Hirai, H.5
-
16
-
-
12144289595
-
High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets
-
Muller-Tidow C, Schwable J, Steffen B, Tidow N, Brandt B, et al. (2004) High-throughput analysis of genome-wide receptor tyrosine kinase expression in human cancers identifies potential novel drug targets. Clin Cancer Res 10 (4): 1241-1249.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.4
, pp. 1241-1249
-
-
Muller-Tidow, C.1
Schwable, J.2
Steffen, B.3
Tidow, N.4
Brandt, B.5
-
17
-
-
20144389173
-
Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer
-
Muller-Tidow C, Diederichs S, Bulk E, Pohle T, Steffen B, et al. (2005) Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer. Cancer Res 65 (5): 1778-1782.
-
(2005)
Cancer Res
, vol.65
, Issue.5
, pp. 1778-1782
-
-
Muller-Tidow, C.1
Diederichs, S.2
Bulk, E.3
Pohle, T.4
Steffen, B.5
-
18
-
-
1642474212
-
Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus
-
Li N, Nakamura K, Jiang Y, Tsurui H, Matsuoka S, et al. (2004) Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus. Hum Mol Genet 13 (2): 171-179.
-
(2004)
Hum Mol Genet
, vol.13
, Issue.2
, pp. 171-179
-
-
Li, N.1
Nakamura, K.2
Jiang, Y.3
Tsurui, H.4
Matsuoka, S.5
-
19
-
-
33847389237
-
Anterograde Jelly belly and Alk receptor tyrosine kinase signaling mediates retinal axon targeting in Drosophila
-
Bazigou E, Apitz H, Johansson J, Loren CE, Hirst EM, et al. (2007) Anterograde Jelly belly and Alk receptor tyrosine kinase signaling mediates retinal axon targeting in Drosophila. Cell 128 (5): 961-975.
-
(2007)
Cell
, vol.128
, Issue.5
, pp. 961-975
-
-
Bazigou, E.1
Apitz, H.2
Johansson, J.3
Loren, C.E.4
Hirst, E.M.5
-
20
-
-
38149121417
-
Behavioral and neurochemical alterations in mice deficient in anaplastic lymphoma kinase suggest therapeutic potential for psychiatric indications
-
Bilsland JG, Wheeldon A, Mead A, Znamenskiy P, Almond S, et al. (2008) Behavioral and neurochemical alterations in mice deficient in anaplastic lymphoma kinase suggest therapeutic potential for psychiatric indications. Neuropsychopharmacology 33 (3): 685-700.
-
(2008)
Neuropsychopharmacology
, vol.33
, Issue.3
, pp. 685-700
-
-
Bilsland, J.G.1
Wheeldon, A.2
Mead, A.3
Znamenskiy, P.4
Almond, S.5
-
21
-
-
0031035052
-
Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system
-
Iwahara T, Fujimoto J, Wen D, Cupples R, Bucay N, et al. (1997) Molecular characterization of ALK, a receptor tyrosine kinase expressed specifically in the nervous system. Oncogene 14 (4): 439-449.
-
(1997)
Oncogene
, vol.14
, Issue.4
, pp. 439-449
-
-
Iwahara, T.1
Fujimoto, J.2
Wen, D.3
Cupples, R.4
Bucay, N.5
-
22
-
-
0035907231
-
Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin
-
Stoica GE, Kuo A, Aigner A, Sunitha I, Souttou B, et al. (2001) Identification of anaplastic lymphoma kinase as a receptor for the growth factor pleiotrophin. J Biol Chem 276 (20): 16772-16779.
-
(2001)
J Biol Chem
, vol.276
, Issue.20
, pp. 16772-16779
-
-
Stoica, G.E.1
Kuo, A.2
Aigner, A.3
Sunitha, I.4
Souttou, B.5
-
23
-
-
0037184128
-
Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types
-
Stoica GE, Kuo A, Powers C, Bowden ET, Sale EB, et al. (2002) Midkine binds to anaplastic lymphoma kinase (ALK) and acts as a growth factor for different cell types. J Biol Chem 277 (39): 35990-35998.
-
(2002)
J Biol Chem
, vol.277
, Issue.39
, pp. 35990-35998
-
-
Stoica, G.E.1
Kuo, A.2
Powers, C.3
Bowden, E.T.4
Sale, E.B.5
-
24
-
-
22544440004
-
Activation and inhibition of anaplastic lymphoma kinase receptor tyrosine kinase by monoclonal antibodies and absence of agonist activity of pleiotrophin
-
Moog-Lutz C, Degoutin J, Gouzi JY, Frobert Y, Brunet-de Carvalho N, et al. (2005) Activation and inhibition of anaplastic lymphoma kinase receptor tyrosine kinase by monoclonal antibodies and absence of agonist activity of pleiotrophin. J Biol Chem 280 (28): 26039-26048.
-
(2005)
J Biol Chem
, vol.280
, Issue.28
, pp. 26039-26048
-
-
Moog-Lutz, C.1
Degoutin, J.2
Gouzi, J.Y.3
Frobert, Y.4
Brunet-de Carvalho, N.5
-
25
-
-
35148838039
-
In contrast to agonist monoclonal antibodies, both C-terminal truncated form and full length form of Pleiotrophin failed to activate vertebrate ALK (anaplastic lymphoma kinase)?
-
Mathivet T, Mazot P, Vigny M, (2007) In contrast to agonist monoclonal antibodies, both C-terminal truncated form and full length form of Pleiotrophin failed to activate vertebrate ALK (anaplastic lymphoma kinase)? Cell Signal 19 (12): 2434-2443.
-
(2007)
Cell Signal
, vol.19
, Issue.12
, pp. 2434-2443
-
-
Mathivet, T.1
Mazot, P.2
Vigny, M.3
-
26
-
-
0029020912
-
Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor
-
Daly NL, Scanlon MJ, Djordjevic JT, Kroon PA, Smith R, (1995) Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor. Proc Natl Acad Sci U S A 92 (14): 6334-6338.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, Issue.14
, pp. 6334-6338
-
-
Daly, N.L.1
Scanlon, M.J.2
Djordjevic, J.T.3
Kroon, P.A.4
Smith, R.5
-
27
-
-
0030759357
-
Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
-
Fass D, Blacklow S, Kim PS, Berger JM, (1997) Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module. Nature 388 (6643): 691-693.
-
(1997)
Nature
, vol.388
, Issue.6643
, pp. 691-693
-
-
Fass, D.1
Blacklow, S.2
Kim, P.S.3
Berger, J.M.4
-
28
-
-
66949152073
-
Anaplastic lymphoma kinase: signalling in development and disease
-
Palmer RH, Vernersson E, Grabbe C, Hallberg B, (2009) Anaplastic lymphoma kinase: signalling in development and disease. Biochem J 420 (3): 345-361.
-
(2009)
Biochem J
, vol.420
, Issue.3
, pp. 345-361
-
-
Palmer, R.H.1
Vernersson, E.2
Grabbe, C.3
Hallberg, B.4
-
29
-
-
65749083100
-
Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy
-
Webb TR, Slavish J, George RE, Look AT, Xue L, et al. (2009) Anaplastic lymphoma kinase: role in cancer pathogenesis and small-molecule inhibitor development for therapy. Expert Rev Anticancer Ther 9 (3): 331-356.
-
(2009)
Expert Rev Anticancer Ther
, vol.9
, Issue.3
, pp. 331-356
-
-
Webb, T.R.1
Slavish, J.2
George, R.E.3
Look, A.T.4
Xue, L.5
-
30
-
-
0028198206
-
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma
-
Morris SW, Kirstein MN, Valentine MB, Dittmer KG, Shapiro DN, et al. (1994) Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma. Science 263 (5151): 1281-1284.
-
(1994)
Science
, vol.263
, Issue.5151
, pp. 1281-1284
-
-
Morris, S.W.1
Kirstein, M.N.2
Valentine, M.B.3
Dittmer, K.G.4
Shapiro, D.N.5
-
31
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, et al. (2007) Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 448 (7153): 561-566.
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
Takada, S.4
Yamashita, Y.5
-
32
-
-
36849065315
-
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
-
Rikova K, Guo A, Zeng Q, Possemato A, Yu J, et al. (2007) Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell 131 (6): 1190-1203.
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1190-1203
-
-
Rikova, K.1
Guo, A.2
Zeng, Q.3
Possemato, A.4
Yu, J.5
-
33
-
-
58149289668
-
High incidence of DNA mutations and gene amplifications of the ALK gene in advanced sporadic neuroblastoma tumours
-
Caren H, Abel F, Kogner P, Martinsson T, (2008) High incidence of DNA mutations and gene amplifications of the ALK gene in advanced sporadic neuroblastoma tumours. Biochem J 416 (2): 153-159.
-
(2008)
Biochem J
, vol.416
, Issue.2
, pp. 153-159
-
-
Caren, H.1
Abel, F.2
Kogner, P.3
Martinsson, T.4
-
34
-
-
54049118823
-
Oncogenic mutations of ALK kinase in neuroblastoma
-
Chen Y, Takita J, Choi YL, Kato M, Ohira M, et al. (2008) Oncogenic mutations of ALK kinase in neuroblastoma. Nature 455 (7215): 971-974.
-
(2008)
Nature
, vol.455
, Issue.7215
, pp. 971-974
-
-
Chen, Y.1
Takita, J.2
Choi, Y.L.3
Kato, M.4
Ohira, M.5
-
35
-
-
54049120220
-
Activating mutations in ALK provide a therapeutic target in neuroblastoma
-
George RE, Sanda T, Hanna M, Frohling S, Luther W 2nd, et al. (2008) Activating mutations in ALK provide a therapeutic target in neuroblastoma. Nature 455 (7215): 975-978.
-
(2008)
Nature
, vol.455
, Issue.7215
, pp. 975-978
-
-
George, R.E.1
Sanda, T.2
Hanna, M.3
Frohling, S.4
Luther II, W.5
-
36
-
-
54049149961
-
Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma
-
Janoueix-Lerosey I, Lequin D, Brugieres L, Ribeiro A, de Pontual L, et al. (2008) Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma. Nature 455 (7215): 967-970.
-
(2008)
Nature
, vol.455
, Issue.7215
, pp. 967-970
-
-
Janoueix-Lerosey, I.1
Lequin, D.2
Brugieres, L.3
Ribeiro, A.4
de Pontual, L.5
-
37
-
-
54049094708
-
Identification of ALK as a major familial neuroblastoma predisposition gene
-
Mosse YP, Laudenslager M, Longo L, Cole KA, Wood A, et al. (2008) Identification of ALK as a major familial neuroblastoma predisposition gene. Nature 455 (7215): 930-935.
-
(2008)
Nature
, vol.455
, Issue.7215
, pp. 930-935
-
-
Mosse, Y.P.1
Laudenslager, M.2
Longo, L.3
Cole, K.A.4
Wood, A.5
-
38
-
-
34248561977
-
Anaplastic lymphoma kinase is expressed in different subtypes of human breast cancer
-
Perez-Pinera P, Chang Y, Astudillo A, Mortimer J, Deuel TF, (2007) Anaplastic lymphoma kinase is expressed in different subtypes of human breast cancer. Biochem Biophys Res Commun 358 (2): 399-403.
-
(2007)
Biochem Biophys Res Commun
, vol.358
, Issue.2
, pp. 399-403
-
-
Perez-Pinera, P.1
Chang, Y.2
Astudillo, A.3
Mortimer, J.4
Deuel, T.F.5
-
39
-
-
33845419068
-
Identification of squamous cell carcinoma associated proteins by proteomics and loss of beta tropomyosin expression in esophageal cancer
-
Jazii FR, Najafi Z, Malekzadeh R, Conrads TP, Ziaee AA, et al. (2006) Identification of squamous cell carcinoma associated proteins by proteomics and loss of beta tropomyosin expression in esophageal cancer. World J Gastroenterol 12 (44): 7104-7112.
-
(2006)
World J Gastroenterol
, vol.12
, Issue.44
, pp. 7104-7112
-
-
Jazii, F.R.1
Najafi, Z.2
Malekzadeh, R.3
Conrads, T.P.4
Ziaee, A.A.5
-
40
-
-
34447536140
-
Proteomic profiling of proteins dysregulted in Chinese esophageal squamous cell carcinoma
-
Du XL, Hu H, Lin DC, Xia SH, Shen XM, et al. (2007) Proteomic profiling of proteins dysregulted in Chinese esophageal squamous cell carcinoma. J Mol Med 85 (8): 863-875.
-
(2007)
J Mol Med
, vol.85
, Issue.8
, pp. 863-875
-
-
Du, X.L.1
Hu, H.2
Lin, D.C.3
Xia, S.H.4
Shen, X.M.5
-
41
-
-
44849126091
-
Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors
-
McDermott U, Iafrate AJ, Gray NS, Shioda T, Classon M, et al. (2008) Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors. Cancer Res 68 (9): 3389-3395.
-
(2008)
Cancer Res
, vol.68
, Issue.9
, pp. 3389-3395
-
-
McDermott, U.1
Iafrate, A.J.2
Gray, N.S.3
Shioda, T.4
Classon, M.5
-
42
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, Shaw AT, Solomon B, et al. (2010) Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 363 (18): 1693-1703.
-
(2010)
N Engl J Med
, vol.363
, Issue.18
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
Shaw, A.T.4
Solomon, B.5
-
43
-
-
82555205501
-
New Strategies for Treatment of ALK Rearranged Non-Small Cell Lung Cancers
-
Sasaki T, Janne PA, (2011) New Strategies for Treatment of ALK Rearranged Non-Small Cell Lung Cancers. Clin Cancer Res.
-
(2011)
Clin Cancer Res
-
-
Sasaki, T.1
Janne, P.A.2
-
44
-
-
79954601408
-
Novel targeted therapeutics: inhibitors of MDM2, ALK and PARP
-
Yuan Y, Liao YM, Hsueh CT, Mirshahidi HR, (2011) Novel targeted therapeutics: inhibitors of MDM2, ALK and PARP. J Hematol Oncol 4: 16.
-
(2011)
J Hematol Oncol
, vol.4
, pp. 16
-
-
Yuan, Y.1
Liao, Y.M.2
Hsueh, C.T.3
Mirshahidi, H.R.4
-
45
-
-
37549060017
-
EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
-
Inamura K, Takeuchi K, Togashi Y, Nomura K, Ninomiya H, et al. (2008) EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol 3 (1): 13-17.
-
(2008)
J Thorac Oncol
, vol.3
, Issue.1
, pp. 13-17
-
-
Inamura, K.1
Takeuchi, K.2
Togashi, Y.3
Nomura, K.4
Ninomiya, H.5
-
46
-
-
34249935172
-
Peripheral T-cell lymphomas
-
Savage KJ, (2007) Peripheral T-cell lymphomas. Blood Rev 21 (4): 201-216.
-
(2007)
Blood Rev
, vol.21
, Issue.4
, pp. 201-216
-
-
Savage, K.J.1
-
47
-
-
28444478439
-
Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants
-
Greulich H, Chen TH, Feng W, Janne PA, Alvarez JV, et al. (2005) Oncogenic transformation by inhibitor-sensitive and-resistant EGFR mutants. PLoS Med 2 (11): e313.
-
(2005)
PLoS Med
, vol.2
, Issue.11
-
-
Greulich, H.1
Chen, T.H.2
Feng, W.3
Janne, P.A.4
Alvarez, J.V.5
-
48
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, Gurubhagavatula S, Okimoto RA, et al. (2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350 (21): 2129-2139.
-
(2004)
N Engl J Med
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
-
49
-
-
2342624080
-
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, Tracy S, Greulich H, et al. (2004) EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304 (5676): 1497-1500.
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
-
50
-
-
33646690478
-
Kinase mutations in cancer: chinks in the enemy's armour?
-
Di Nicolantonio F, Bardelli A, (2006) Kinase mutations in cancer: chinks in the enemy's armour? Curr Opin Oncol 18 (1): 69-76.
-
(2006)
Curr Opin Oncol
, vol.18
, Issue.1
, pp. 69-76
-
-
Di Nicolantonio, F.1
Bardelli, A.2
-
51
-
-
0036270593
-
A major breakpoint cluster domain in murine radiation-induced acute myeloid leukemia
-
Finnon R, Moody J, Meijne E, Haines J, Clark D, et al. (2002) A major breakpoint cluster domain in murine radiation-induced acute myeloid leukemia. Mol Carcinog 34 (2): 64-71.
-
(2002)
Mol Carcinog
, vol.34
, Issue.2
, pp. 64-71
-
-
Finnon, R.1
Moody, J.2
Meijne, E.3
Haines, J.4
Clark, D.5
-
52
-
-
0030761514
-
The role of the Shc phosphotyrosine interaction/phosphotyrosine binding domain and tyrosine phosphorylation sites in polyoma middle T antigen-mediated cell transformation
-
Blaikie PA, Fournier E, Dilworth SM, Birnbaum D, Borg JP, et al. (1997) The role of the Shc phosphotyrosine interaction/phosphotyrosine binding domain and tyrosine phosphorylation sites in polyoma middle T antigen-mediated cell transformation. J Biol Chem 272 (33): 20671-20677.
-
(1997)
J Biol Chem
, vol.272
, Issue.33
, pp. 20671-20677
-
-
Blaikie, P.A.1
Fournier, E.2
Dilworth, S.M.3
Birnbaum, D.4
Borg, J.P.5
-
53
-
-
0027934261
-
Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins
-
Salcini AE, McGlade J, Pelicci G, Nicoletti I, Pawson T, et al. (1994) Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins. Oncogene 9 (10): 2827-2836.
-
(1994)
Oncogene
, vol.9
, Issue.10
, pp. 2827-2836
-
-
Salcini, A.E.1
McGlade, J.2
Pelicci, G.3
Nicoletti, I.4
Pawson, T.5
-
54
-
-
79955474560
-
The constitutive activity of the ALK mutated at positions F1174 or R1275 impairs receptor trafficking
-
Mazot P, Cazes A, Boutterin MC, Figueiredo A, Raynal V, et al. (2011) The constitutive activity of the ALK mutated at positions F1174 or R1275 impairs receptor trafficking. Oncogene 30 (17): 2017-2025.
-
(2011)
Oncogene
, vol.30
, Issue.17
, pp. 2017-2025
-
-
Mazot, P.1
Cazes, A.2
Boutterin, M.C.3
Figueiredo, A.4
Raynal, V.5
-
55
-
-
78049353081
-
Anaplastic Lymphoma Kinase: role in specific tumours, and development of small molecule inhibitors for cancer therapy
-
Ardini E, Magnaghi P, Orsini P, Galvani A, Menichincheri M, (2010) Anaplastic Lymphoma Kinase: role in specific tumours, and development of small molecule inhibitors for cancer therapy. Cancer Lett 299 (2): 81-94.
-
(2010)
Cancer Lett
, vol.299
, Issue.2
, pp. 81-94
-
-
Ardini, E.1
Magnaghi, P.2
Orsini, P.3
Galvani, A.4
Menichincheri, M.5
-
56
-
-
67749139806
-
Clinical analysis of primary systemic anaplastic large cell lymphoma: a report of 57 cases
-
Wang FH, Li YH, Zeng J, Rao HL, Xia ZJ, et al. (2009) Clinical analysis of primary systemic anaplastic large cell lymphoma: a report of 57 cases. Ai Zheng 28 (1): 49-53.
-
(2009)
Ai Zheng
, vol.28
, Issue.1
, pp. 49-53
-
-
Wang, F.H.1
Li, Y.H.2
Zeng, J.3
Rao, H.L.4
Xia, Z.J.5
-
57
-
-
77952774104
-
Activation of JAK2-V617F by components of heterodimeric cytokine receptors
-
Pradhan A, Lambert QT, Griner LN, Reuther GW, (2010) Activation of JAK2-V617F by components of heterodimeric cytokine receptors. J Biol Chem 285 (22): 16651-16663.
-
(2010)
J Biol Chem
, vol.285
, Issue.22
, pp. 16651-16663
-
-
Pradhan, A.1
Lambert, Q.T.2
Griner, L.N.3
Reuther, G.W.4
-
58
-
-
0034462588
-
Identification and characterization of an activating TrkA deletion mutation in acute myeloid leukemia
-
Reuther GW, Lambert QT, Caligiuri MA, Der CJ, (2000) Identification and characterization of an activating TrkA deletion mutation in acute myeloid leukemia. Mol Cell Biol 20 (23): 8655-8666.
-
(2000)
Mol Cell Biol
, vol.20
, Issue.23
, pp. 8655-8666
-
-
Reuther, G.W.1
Lambert, Q.T.2
Caligiuri, M.A.3
Der, C.J.4
-
59
-
-
36749024030
-
Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor
-
Pradhan A, Lambert QT, Reuther GW, (2007) Transformation of hematopoietic cells and activation of JAK2-V617F by IL-27R, a component of a heterodimeric type I cytokine receptor. Proc Natl Acad Sci U S A 104 (47): 18502-18507.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, Issue.47
, pp. 18502-18507
-
-
Pradhan, A.1
Lambert, Q.T.2
Reuther, G.W.3
|