Heart-specific activation of LTK results in cardiac hypertrophy, cardiomyocyte degeneration and gene reprogramming in transgenic mice

Oncogene

Volumn 18, Issue 26, 1999, Pages 3821-3830

  Honda, Hiroaki ^a   Harada, Koichiro ^a   Komuro, Issei ^a   Terasaki, Fumio ^b   Ueno, Hiroo ^a   Tanaka, Yuji ^a   Kawamura, Keishiro ^b   Yazaki, Yoshio ^a   Hirai, Hisamaru ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Leukocyte tyrosine kinase (LKT); Protein tyrosine kinase; Transgenic mice

Indexed keywords

ALPHA ACTIN; BETA ACTIN; INSULIN RECEPTOR KINASE; LEUKOCYTE ENZYME; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CELL DEGENERATION; CONTROLLED STUDY; CYTOMEGALOVIRUS; ECHOCARDIOGRAPHY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HEART MUSCLE CELL; HEART OUTPUT; HEART VENTRICLE HYPERTROPHY; HISTOLOGY; HYPOTENSION; INTRACELLULAR MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SARCOLEMMA; TISSUE SPECIFICITY; TRANSGENIC MOUSE;

ANIMALS; APOPTOSIS; CARDIOMEGALY; CYTOMEGALOVIRUS; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; FETAL PROTEINS; GENE EXPRESSION REGULATION; GROWTH DISORDERS; HEMATOPOIETIC SYSTEM; HEMODYNAMIC PROCESSES; HUMANS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; MUSCLE PROTEINS; MYOCARDIUM; PHOSPHORYLATION; PROMOTER REGIONS (GENETICS); PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR PROTEIN-TYROSINE KINASES;

ANIMALIA; CYTOMEGALOVIRUS; MUS MUSCULUS;

EID: 0033166257     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202736     Document Type: Article

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