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Volumn 2, Issue AUG, 2011, Pages

The serotonin transporter polymorphism (5-HTTLPR) and alcohol problems in heavy drinkers: Moderation by depressive symptoms

Author keywords

5 HTTLPR; Alcohol; Depression; Serotonin; Serotonin transporter polymorphism; SLC6A4

Indexed keywords

SEROTONIN TRANSPORTER;

EID: 84856782104     PISSN: None     EISSN: 16640640     Source Type: Journal    
DOI: 10.3389/fpsyt.2011.00049     Document Type: Article
Times cited : (12)

References (42)
  • 1
    • 0031627516 scopus 로고    scopus 로고
    • What you need to know: detecting alcohol problems in general medical practice
    • Allen, J.,Litten, R. Z., and Lee, A. (1998). What you need to know: detecting alcohol problems in general medical practice. SingaporeMed. J. 39,38-41.
    • (1998) SingaporeMed. J , vol.39 , pp. 38-41
    • Allen, J.1    Litten, R.Z.2    Lee, A.3
  • 2
    • 57549083057 scopus 로고    scopus 로고
    • A serotonin transporter gene polymorphism (5-HTTLPR), drinking-to-cope motivation, and negative life events among college students
    • Armeli, S.,Conner, T. S.,Covault, J.,Ten-nen, H.,and Kranzler, H. R. (2008). A serotonin transporter gene polymorphism (5-HTTLPR), drinking-to-cope motivation, and negative life events among college students. J. Stud. Alcohol Drugs 69, 814-823.
    • (2008) J. Stud. Alcohol Drugs , vol.69 , pp. 814-823
    • Armeli, S.1    Conner, T.S.2    Covault, J.3    Ten-nen, H.4    Kranzler, H.R.5
  • 3
    • 7744240079 scopus 로고    scopus 로고
    • Interaction between serotonin transporter gene variation and rearing condition in alcohol preference and consumption in female primates
    • Barr, C. S., Newman, T. K., Lindell, S., Shannon, C., Champoux, M., Lesch, K. P., Suomi, S. J., Goldman, D., and Higley, J. D. (2004). Interaction between serotonin transporter gene variation and rearing condition in alcohol preference and consumption in female primates. Arch. Gen. Psychiatry 61, 1146-1152.
    • (2004) Arch. Gen. Psychiatry , vol.61 , pp. 1146-1152
    • Barr, C.S.1    Newman, T.K.2    Lindell, S.3    Shannon, C.4    Champoux, M.5    Lesch, K.P.6    Suomi, S.J.7    Goldman, D.8    Higley, J.D.9
  • 4
    • 35649011434 scopus 로고    scopus 로고
    • Association of the long allele of the 5-HTTLPR polymorphism with compulsive craving in alcohol dependence
    • Bleich, S., Bonsch, D., Rauh, J., Bay-erlein, K., Fiszer, R., Frieling, H., and Hillemacher, T. (2007). Association of the long allele of the 5-HTTLPR polymorphism with compulsive craving in alcohol dependence. Alcohol Alcohol. 42, 509-512.
    • (2007) Alcohol Alcohol , vol.42 , pp. 509-512
    • Bleich, S.1    Bonsch, D.2    Rauh, J.3    Bay-erlein, K.4    Fiszer, R.5    Frieling, H.6    Hillemacher, T.7
  • 7
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: moderation by a polymorphism in the 5-HTT Gene
    • Caspi, A. (2003). Influence of life stress on depression: moderation by a polymorphism in the 5-HTT Gene. Science 301.
    • (2003) Science , pp. 301
    • Caspi, A.1
  • 8
    • 77951854270 scopus 로고    scopus 로고
    • Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits
    • Caspi, A., Hariri, A. R., Holmes, A., Uher, R., and Moffitt, T. E. (2010). Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits. Am. J. Psychiatry 167, 509-527.
    • (2010) Am. J. Psychiatry , vol.167 , pp. 509-527
    • Caspi, A.1    Hariri, A.R.2    Holmes, A.3    Uher, R.4    Moffitt, T.E.5
  • 9
    • 58249140206 scopus 로고    scopus 로고
    • Binge drinking in young adults: data, definitions, and determinants
    • Courtney, K. E., and Polich, J. (2009). Binge drinking in young adults: data, definitions, and determinants. Psy-chol Bull. 135, 142-156.
    • (2009) Psy-chol Bull , vol.135 , pp. 142-156
    • Courtney, K.E.1    Polich, J.2
  • 10
    • 33847292324 scopus 로고    scopus 로고
    • Interactive effects of the serotonin transporter 5-HTTLPR polymorphism and stressful life events on college student drinking and drug use
    • Covault, J., Tennen, H., Armeli, S., Conner, T. S., Herman, A. I., Cillessen, A. H.,andKranzler,H.R. (2007).Interactive effects of the serotonin transporter 5-HTTLPR polymorphism and stressful life events on college student drinking and drug use. Biol. Psychiatry 61, 609-616.
    • (2007) Biol. Psychiatry , vol.61 , pp. 609-616
    • Covault, J.1    Tennen, H.2    Armeli, S.3    Conner, T.S.4    Herman, A.I.5    Cillessen, A.H.6    Kranzler, H.R.7
  • 11
    • 12944333124 scopus 로고    scopus 로고
    • Meta-analysis of the association of a functional serotonin transporter promoter polymorphism with alcohol dependence
    • Feinn, R., Nellissery, M., and Kran-zler, H. R. (2005). Meta-analysis of the association of a functional serotonin transporter promoter polymorphism with alcohol dependence. Am. J. Med. Genet. B Neuropsychiatr. Genet. 133B, 79-84.
    • (2005) Am. J. Med. Genet. B Neuropsychiatr. Genet , vol.133 B , pp. 79-84
    • Feinn, R.1    Nellissery, M.2    Kran-zler, H.R.3
  • 12
    • 2942522762 scopus 로고    scopus 로고
    • The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States 1991-1992 and 2001-2002
    • Grant, B. F., Dawson, D. A., Stinson, F. S., Chou, S. P., Dufour, M. C., and Pickering, R. P. (2004). The 12-month prevalence and trends in DSM-IV alcohol abuse and dependence: United States, 1991-1992 and 2001-2002. DrugAlcohol Depend. 74, 223-234.
    • (2004) DrugAlcohol Depend , vol.74 , pp. 223-234
    • Grant, B.F.1    Dawson, D.A.2    Stinson, F.S.3    Chou, S.P.4    Dufour, M.C.5    Pickering, R.P.6
  • 14
    • 34347394132 scopus 로고    scopus 로고
    • Prevalence, correlates, disability, and comorbid-ity of DSM-IV alcohol abuse and dependence in the United States: results from the National Epidemio-logic Survey on Alcohol and Related Conditions
    • Hasin, D. S., Stinson, F. S., Ogburn, E., and Grant, B. F. (2007). Prevalence, correlates, disability, and comorbid-ity of DSM-IV alcohol abuse and dependence in the United States: results from the National Epidemio-logic Survey on Alcohol and Related Conditions. Arch. Gen. Psychiatry 64, 830-842.
    • (2007) Arch. Gen. Psychiatry , vol.64 , pp. 830-842
    • Hasin, D.S.1    Stinson, F.S.2    Ogburn, E.3    Grant, B.F.4
  • 15
    • 0031435392 scopus 로고    scopus 로고
    • The human serotonin transporter gene polymorphism - basic research and clinical implications
    • Heils, A., Mossner, R., and Lesch, K. P. (1997). The human serotonin transporter gene polymorphism - basic research and clinical implications. J. NeuralTransm. 104,1005-1014.
    • (1997) J. Neural Transm. , vol.104 , pp. 1005-1014
    • Heils, A.1    Mossner, R.2    Lesch, K.P.3
  • 17
  • 18
    • 33746257088 scopus 로고    scopus 로고
    • Low level of response to alcohol as associated with serotonin transporter genotype and high alcohol intake in adolescents
    • Hinckers, A. S., Laucht, M., Schmidt, M. H., Mann, K. F., Schumann, G., Schuckit, M. A., and Heinz, A. (2006). Low level of response to alcohol as associated with serotonin transporter genotype and high alcohol intake in adolescents. Biol. Psychiatry 60,282-287.
    • (2006) Biol. Psychiatry , vol.60 , pp. 282-287
    • Hinckers, A.S.1    Laucht, M.2    Schmidt, M.H.3    Mann, K.F.4    Schumann, G.5    Schuckit, M.A.6    Heinz, A.7
  • 19
    • 66249097082 scopus 로고    scopus 로고
    • Age of drinking onset, alcohol use disorders, frequent heavy drinking, and unintentionally injuring oneself and others after drinking
    • Hingson,R. W.,andZha,W. (2009). Age of drinking onset, alcohol use disorders, frequent heavy drinking, and unintentionally injuring oneself and others after drinking. Pediatrics 123, 1477-1484.
    • (2009) Pediatrics , vol.123 , pp. 1477-1484
    • Hingson, R.W.1    Zha, W.2
  • 20
    • 12344328265 scopus 로고    scopus 로고
    • An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk
    • Hu, X., Oroszi, G., Chun, J., Smith, T. L., Goldman, D., and Schuckit, M. A. (2005). An expanded evaluation of the relationship of four alleles to the level of response to alcohol and the alcoholism risk. Alcohol. Clin. Exp. Res. 29, 8-16.
    • (2005) Alcohol. Clin. Exp. Res. , vol.29 , pp. 8-16
    • Hu, X.1    Oroszi, G.2    Chun, J.3    Smith, T.L.4    Goldman, D.5    Schuckit, M.A.6
  • 21
    • 0033777068 scopus 로고    scopus 로고
    • Serotonergic agents and alcoholism treatment: rebirth of the subtype concept - an hypothesis
    • Johnson, B. A. (2000). Serotonergic agents and alcoholism treatment: rebirth of the subtype concept - an hypothesis. Alcohol. Clin. Exp. Res. 24, 1597-1601.
    • (2000) Alcohol. Clin. Exp. Res. , vol.24 , pp. 1597-1601
    • Johnson, B.A.1
  • 22
    • 10844261674 scopus 로고    scopus 로고
    • Role of the serotonergic system in the neurobiology of alcoholism: implications for treatment
    • Johnson, B. A. (2004). Role of the serotonergic system in the neurobiology of alcoholism: implications for treatment. CNS Drugs 18, 1105-1118.
    • (2004) CNS Drugs , vol.18 , pp. 1105-1118
    • Johnson, B.A.1
  • 24
    • 33746119111 scopus 로고    scopus 로고
    • The temporal relationship of the onsets of alcohol dependence and major depression: using a genetically informative study design
    • Kuo, P. H., Gardner, C. O., Kendler, K. S., and Prescott, C. A. (2006). The temporal relationship of the onsets of alcohol dependence and major depression: using a genetically informative study design. Psychol Med. 36, 1153-1162.
    • (2006) Psychol Med , vol.36 , pp. 1153-1162
    • Kuo, P.H.1    Gardner, C.O.2    Kendler, K.S.3    Prescott, C.A.4
  • 25
    • 15544367024 scopus 로고    scopus 로고
    • Association of the serotonin transporter gene polymorphism with Korean male alcoholics
    • Kweon, Y. S., Lee, H. K., Lee, C. T., Lee, K. U., and Pae, C. U. (2005). Association of the serotonin transporter gene polymorphism with Korean male alcoholics. J. Psychiatr. Res. 39, 371-376.
    • (2005) J. Psychiatr. Res. , vol.39 , pp. 371-376
    • Kweon, Y.S.1    Lee, H.K.2    Lee, C.T.3    Lee, K.U.4    Pae, C.U.5
  • 28
    • 77649183574 scopus 로고    scopus 로고
    • The serotonin transporter gene and risk for alcohol dependence: a meta-analytic review
    • McHugh, R. K., Hofmann, S. G., Asnaani, A., Sawyer, A. T., and Otto, M. W. (2010). The serotonin transporter gene and risk for alcohol dependence: a meta-analytic review. DrugAlcohol Depend. 108,1-6.
    • (2010) DrugAlcohol Depend , vol.108 , pp. 1-6
    • McHugh, R.K.1    Hofmann, S.G.2    Asnaani, A.3    Sawyer, A.T.4    Otto, M.W.5
  • 29
    • 79954997507 scopus 로고    scopus 로고
    • Effects of the serotonin transporter (5-HTTLPR) and alpha2A-adrenoceptor (C-1291G) genotypes on substance use in children and adolescents: a longitudinal study
    • Merenakk, L., Maestu, J., Nordquist, N., Parik, J., Orel and, L., Loit, H. M., and Harro, J. (2011). Effects of the serotonin transporter (5-HTTLPR) and alpha2A-adrenoceptor (C-1291G) genotypes on substance use in children and adolescents: a longitudinal study. Psychopharmacology (Berl.) 215, 13-22.
    • (2011) Psychopharmacology (Berl. ) , vol.215 , pp. 13-22
    • Merenakk, L.1    Maestu, J.2    Nordquist, N.3    Parik, J.4    Oreland, L.5    Loit, H.M.6    Harro, J.7
  • 30
    • 27744588449 scopus 로고    scopus 로고
    • Association between 5-HTTLPR genotypes and persisting patterns of anxiety and alcohol use: results from a 10-year longitudinal study of adolescent mental health
    • Olsson, C. A., Byrnes, G. B., Lotfi-Miri, M., Collins, V., Williamson, R., Patton, C., and Anney, R. J. (2005). Association between 5-HTTLPR genotypes and persisting patterns of anxiety and alcohol use: results from a 10-year longitudinal study of adolescent mental health. Mol. Psychiatry 10, 868-876.
    • (2005) Mol. Psychiatry , vol.10 , pp. 868-876
    • Olsson, C.A.1    Byrnes, G.B.2    Lotfi-Miri, M.3    Collins, V.4    Williamson, R.5    Patton, C.6    Anney, R.J.7
  • 31
    • 46949090009 scopus 로고    scopus 로고
    • The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies
    • Philibert, R. A., Sandhu, H., Hollen-beck, N., Gunter, T., Adams, W., andMadan,A. (2008). The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B,543-549.
    • (2008) Am. J. Med. Genet. B Neuropsychiatr. Genet. , vol.147 B , pp. 543-549
    • Philibert, R.A.1    Sandhu, H.2    Hollen-beck, N.3    Gunter, T.4    Adams, W.5    Madan, A.6
  • 32
    • 0032782068 scopus 로고    scopus 로고
    • Sex differences in the sources of genetic liability to alcohol abuse and dependence in a population-based sample of U.S. twins.
    • Prescott, C. A., Aggen, S. H., and Kendler, K. S. (1999). Sex differences in the sources of genetic liability to alcohol abuse and dependence in a population-based sample of U.S. twins. Alcohol. Clin. Exp. Res. 23, 1136-1144.
    • (1999) Alcohol. Clin. Exp. Res , vol.23 , pp. 1136-1144
    • Prescott, C.A.1    Aggen, S.H.2    Kendler, K.S.3
  • 33
    • 78650382438 scopus 로고    scopus 로고
    • Stress-induced, and cue-induced craving for alcohol in heavy drinkers: preliminary evidence of genetic moderation by the OPRM1 and CRH-BP genes
    • Ray, L. A. (2010). Stress-induced, and cue-induced craving for alcohol in heavy drinkers: preliminary evidence of genetic moderation by the OPRM1 and CRH-BP genes. Alcohol. Clin. Exp. Res. 35,166-174.
    • (2010) Alcohol. Clin. Exp. Res , vol.35 , pp. 166-174
    • Ray, L.A.1
  • 34
    • 0031706428 scopus 로고    scopus 로고
    • On the validity of the Beck depression inventory.A review.
    • Richter, P., Werner, J., Heerlein, A., Kraus, A., and Sauer, H. (1998). On the validity of the Beck depression inventory. A review. Psychopathology 31, 160-168.
    • (1998) Psychopathology , vol.31 , pp. 160-168
    • Richter, P.1    Werner, J.2    Heerlein, A.3    Kraus, A.4    Sauer, H.5
  • 35
    • 1642504265 scopus 로고    scopus 로고
    • Impact of psychiatric comorbidity on treatment of adolescent drug abusers
    • Rowe, C. L., Liddle, H. A., Greenbaum, P. E., and Henderson, C. E. (2004). Impact of psychiatric comorbidity on treatment of adolescent drug abusers. J. Subst. Abuse Treat. 26, 129-140.
    • (2004) J. Subst. Abuse Treat. , vol.26 , pp. 129-140
    • Rowe, C.L.1    Liddle, H.A.2    Greenbaum, P.E.3    Henderson, C.E.4
  • 36
    • 60249096629 scopus 로고    scopus 로고
    • An overview of genetic influences in alcoholism
    • Schuckit, M. A. (2009). An overview of genetic influences in alcoholism. J. Subst. Abuse Treat. 36, S5-S14.
    • (2009) J. Subst. Abuse Treat. , vol.36
    • Schuckit, M.A.1
  • 37
    • 33244496698 scopus 로고    scopus 로고
    • An evaluation of the level of response to alcohol, externalizing symptoms, and depressive symptoms as predictors of alcoholism
    • Schuckit, M. A., and Smith, T. L. (2006). An evaluation of the level of response to alcohol, externalizing symptoms, and depressive symptoms as predictors of alcoholism. J. Stud. Alcohol 67,215-227.
    • (2006) J. Stud. Alcohol , vol.67 , pp. 215-227
    • Schuckit, M.A.1    Smith, T.L.2
  • 38
    • 55649086441 scopus 로고    scopus 로고
    • Early-onset depressive disorders predict the use of addictive substances in adolescence: a prospective study of adolescent Finnish twins
    • Sihvola, E., Rose, R. J., Dick, D. M., Pulkkinen, L., Marttunen, M., and Kaprio, J. (2008). Early-onset depressive disorders predict the use of addictive substances in adolescence: a prospective study of adolescent Finnish twins. Addiction 103, 2045-2053.
    • (2008) Addiction , vol.103 , pp. 2045-2053
    • Sihvola, E.1    Rose, R.J.2    Dick, D.M.3    Pulkkinen, L.4    Marttunen, M.5    Kaprio, J.6
  • 39
    • 0033974364 scopus 로고    scopus 로고
    • The comorbidity of depression and substance use disorders
    • Swendsen, J. D., and Merikangas, K. R. (2000). The comorbidity of depression and substance use disorders. Clin. Psychol. Rev. 20, 173-189.
    • (2000) Clin. Psychol. Rev. , vol.20 , pp. 173-189
    • Swendsen, J.D.1    Merikangas, K.R.2
  • 40
    • 0032992990 scopus 로고    scopus 로고
    • The role of neurocognitive abilities in coping with adolescent relapse to alcohol and drug use
    • Tapert, S. F., Brown, S. A., Myers, M. G., and Granholm, E. (1999). The role of neurocognitive abilities in coping with adolescent relapse to alcohol and drug use. J. Stud. Alcohol 60, 500-508.
    • (1999) J. Stud. Alcohol , vol.60 , pp. 500-508
    • Tapert, S.F.1    Brown, S.A.2    Myers, M.G.3    Granholm, E.4
  • 41
    • 46249111854 scopus 로고    scopus 로고
    • Using the Timeline Followback to determine time windows representative of annual alcohol consumption with problem drinkers
    • Vakili, S., Sobell, L. C., Sobell, M. B., Simco, E. R., and Agrawal, S. (2008). Using the Timeline Followback to determine time windows representative of annual alcohol consumption with problem drinkers. Addict. Behav. 33,1123-1130.
    • (2008) Addict. Behav , vol.33 , pp. 1123-1130
    • Vakili, S.1    Sobell, L.C.2    Sobell, M.B.3    Simco, E.R.4    Agrawal, S.5
  • 42
    • 0024571637 scopus 로고
    • Towards the assessment of adolescent problem drinking
    • White, H. R., and Labouvie, E. W. (1989). Towards the assessment of adolescent problem drinking. J. Stud. Alcohol 50, 30-37.
    • (1989) J. Stud. Alcohol , vol.50 , pp. 30-37
    • White, H.R.1    Labouvie, E.W.2


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