Microarray genomic profile of mitochondrial and oxidant response in manganese chloride treated PC12 cells

NeuroToxicology

Volumn 33, Issue 2, 2012, Pages 162-168

  Taka, Equar ^a   Mazzio, Elizabeth ^a   Soliman, Karam F A ^a   Renee Reams, R ^a  

^a FLORIDA A AND M UNIVERSITY   (United States)

Author keywords

CDNA microarray whole genome; Dopamine; GCDH; Heme oxygenase; Manganese; Mitochondria

Indexed keywords

ARSENIC TRIOXIDE; BILIVERDIN; COMPLEMENTARY DNA; ENOLASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GENOMIC DNA; GLUTARYL COENZYME A DEHYDROGENASE; HEME OXYGENASE 1; HYDROGEN PEROXIDE; MANGANESE CHLORIDE; THIOREDOXIN REDUCTASE 1; TRANSCRIPTOME;

ANIMAL CELL; ARSENITE INDUCIBLE RNA ASSOCIATED PROTEIN GENE; ARTICLE; BILIVERDIN REDUCTASE GENE; CELL DEATH; CELL METABOLISM; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY TEST; DITHIOLETHIONE INDUCIBLE GENE 1; ENZYME INDUCTION; GENE; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENOME ANALYSIS; GLYCOLYSIS; HEME OXYGENASE 1 GENE; LD 50; LIPID PEROXIDATION; METABOLIC STRESS; MICROARRAY ANALYSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MOLECULAR DYNAMICS; NONHUMAN; OXIDATIVE STRESS; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THIOREDOXIN REDUCTASE 1 GENE; WESTERN BLOTTING;

ANIMALS; CELL SURVIVAL; CHLORIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GLUCOSE; HEME OXYGENASE-1; HYDROGEN PEROXIDE; LACTIC ACID; MANGANESE COMPOUNDS; MITOCHONDRIA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PC12 CELLS; RATS; RNA, MESSENGER; TIME FACTORS;

RATTUS;

EID: 84856771559     PISSN: 0161813X     EISSN: 18729711     Source Type: Journal    
DOI: 10.1016/j.neuro.2012.01.001     Document Type: Article

References (50)

1. Aschner M., Erikson K.M., Dorman D.C. Manganese dosimetry: species differences and implications for neurotoxicity. Crit Rev Toxicol 2005, 35:1-32.
2. Bjugstad K.B., Crnic L.S., Goodman S.I., Freed C.R. Infant mice with glutaric acidaemia type I have increased vulnerability to 3-nitropropionic acid toxicity. J Inherit Metab Dis 2006, 29:612-619.
3. Chin Y.T., Liao Y.W., Fu M.M., Tu H.P., Shen E.C., Nieh S., et al. Nrf-2 regulates cyclosporine-stimulated HO-1 expression in gingiva. J Dent Res 2011, 90:995-1000.
4. Chiu H., Brittingham J.A., Laskin D.L. Differential induction of heme oxygenase-1 in macrophages and hepatocytes during acetaminophen-induced hepatotoxicity in the rat: effects of hemin and biliverdin. Toxicol Appl Pharmacol 2002, 181:106-115.
5. Christianson D.W. Structural chemistry and biology of manganese metalloenzymes. Prog Biophys Mol Biol 1997, 67:217-252.
6. Chtourou Y., Fetoui H., Sefi M., Trabelsi K., Barkallah M., Boudawara T., et al. Silymarin, a natural antioxidant, protects cerebral cortex against manganese-induced neurotoxicity in adult rats. Biometals 2010, 23:985-996.
7. Collinson E.J., Wimmer-Kleikamp S., Gerega S.K., Yang Y.H., Parish C.R., Dawes I.W., et al. The yeast homolog of heme oxygenase-1 affords cellular antioxidant protection via the transcriptional regulation of known antioxidant genes. J Biol Chem 2011, 286:2205-2214.
8. de Luis E., Larrache J., Garcia-Eulate R., Garcia J.N., Zubieta J.L. Neuroradiologic findings of glutaric aciduria type I. Rev Med Univ Navarra 2007, 51:9-12.
9. Dick R.A., Kwak M.K., Sutter T.R., Kensler T.W. Antioxidative function and substrate specificity of NAD(P)H-dependent alkenal/one oxidoreductase. A new role for leukotriene B4 12-hydroxydehydrogenase/15-oxoprostaglandin 13-reductase. J Biol Chem 2001, 276:40803-40810.
10. dos Santos A.P., Milatovic D., Au C., Yin Z., Batoreu M.C., Aschner M. Rat brain endothelial cells are a target of manganese toxicity. Brain Res 2010, 1326:152-161.
11. Ericson J.E., Crinella F.M., Clarke-Stewart K.A., Allhusen V.D., Chan T., Robertson R.T. Prenatal manganese levels linked to childhood behavioral disinhibition. Neurotoxicol Teratol 2007, 29:181-187.
12. Escartin C., Won S.J., Malgorn C., Auregan G., Berman A.E., Chen P.C., et al. Nuclear factor erythroid 2-related factor 2 facilitates neuronal glutathione synthesis by upregulating neuronal excitatory amino acid transporter 3 expression. J Neurosci 2011, 31:7392-7401.
13. Evans S.M., Casartelli A., Herreros E., Minnick D.T., Day C., George E., et al. Development of a high throughput in vitro toxicity screen predictive of high acute in vivo toxic potential. Toxicol In Vitro 2001, 15:579-584.
14. Greger J.L. Nutrition versus toxicology of manganese in humans: evaluation of potential biomarkers. Neurotoxicology 1999, 20:205-212.
15. Guilarte T.R. Manganese and Parkinson's disease: a critical review and new findings. Ciencia & saude coletiva 2011, 16:4519-4566.
16. Harting I., Neumaier-Probst E., Seitz A., Maier E.M., Assmann B., Baric I., et al. Dynamic changes of striatal and extrastriatal abnormalities in glutaric aciduria type I. Brain 2009, 132:1764-1782.
17. Hussain S., Ali S.F. Manganese scavenges superoxide and hydroxyl radicals: an in vitro study in rats. Neurosci Lett 1999, 261:21-24.
18. Izumi Y., Kume T., Akaike A. Regulation of dopaminergic neuronal death by endogenous dopamine and proteasome activity. Yakugaku Zasshi 2011, 131:21-27.
19. Jiang G., Dai A.G. The pathway of PI3k/Akt-aPKCiota/zeta-Nrf2 regulating the expression of gamma-glutamylcysteine synthetase in the bronchial epithelial cells of rats. Zhongguo Ying Yong Sheng Li Xue Za Zhi 2011, 27:115-119.
20. Lamp J., Keyser B., Koeller D.M., Ullrich K., Braulke T., Muhlhausen C. Glutaric aciduria type 1 metabolites impair the succinate transport from astrocytic to neuronal cells. J Biol Chem 2011, 286:17777-17784.
21. Latini A., Scussiato K., Leipnitz G., Dutra-Filho C.S., Wajner M. Promotion of oxidative stress by 3-hydroxyglutaric acid in rat striatum. J Inherit Metab Dis 2005, 28:57-67.
22. Li H., Wang F., Zhang L., Cao Y., Liu W., Hao J., et al. Modulation of Nrf2 expression alters high glucose-induced oxidative stress and antioxidant gene expression in mouse mesangial cells. Cell Signal 2011.
23. Li H., Wu S., Shi N., Lian S., Lin W. Nrf2/HO-1 pathway activation by manganese is associated with reactive oxygen species and ubiquitin-proteasome pathway, not MAPKs signaling. J Appl Toxicol 2011.
24. Li M., Zhang X., Cui L., Yang R., Wang L., Liu L., et al. The neuroprotection of oxymatrine in cerebral ischemia/reperfusion is related to nuclear factor erythroid 2-related factor 2 (nrf2)-mediated antioxidant response: role of nrf2 and hemeoxygenase-1 expression. Biol Pharm Bull 2011, 34:595-601.
25. Lucchini R., Apostoli P., Perrone C., Placidi D., Albini E., Migliorati P., et al. Long-term exposure to low levels of manganese oxides and neurofunctional changes in ferroalloy workers. Neurotoxicology 1999, 20:287-297.
26. Malecki E.A. Manganese toxicity is associated with mitochondrial dysfunction and DNA fragmentation in rat primary striatal neurons. Brain Res Bull 2001, 55:225-228.
27. Maruyama A., Nishikawa K., Kawatani Y., Mimura J., Hosoya T., Harada N., et al. The novel Nrf2-interacting factor KAP1 regulates susceptibility to oxidative stress by promoting the Nrf2-mediated cytoprotective response. Biochem J 2011, 436:387-397.
28. Mazzio E., Soliman K.F. d-(+)-glucose rescue against 1-methyl-4-phenylpyridinium toxicity through anaerobic glycolysis in neuroblastoma cells. Brain Res 2003, 962:48-60.
29. Mazzio E.A., Soliman K.F. Glioma cell antioxidant capacity relative to reactive oxygen species produced by dopamine. J Appl Toxicol 2004, 24:99-106.
30. Methy D., Bertrand N., Prigent-Tessier A., Stanimirovic D., Beley A., Marie C., et al. HO-1 expression in cerebral endothelial cells in response to sublethal oxidative stress. Brain Res 2004, 1003:151-158.
31. Mizuno K., Kume T., Muto C., Takada-Takatori Y., Izumi Y., Sugimoto H., et al. Glutathione biosynthesis via activation of the nuclear factor E2-related factor 2 (Nrf2) - antioxidant-response element (ARE) pathway is essential for neuroprotective effects of sulforaphane and 6-(methylsulfinyl) hexyl isothiocyanate. J Pharm Sci 2011, 115:320-328.
32. Motterlini R., Mann B.E., Foresti R. Therapeutic applications of carbon monoxide-releasing molecules. Expert Opin Investig Drugs 2005, 14:1305-1318.
33. Na H.K., Kim E.H., Jung J.H., Lee H.H., Hyun J.W., Surh Y.J. (-)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells. Arch Biochem Biophys 2008, 476:171-177.
34. Pae H.O., Chung H.T. Heme oxygenase-1: its therapeutic roles in inflammatory diseases. Immune Network 2009, 9:12-19.
35. Paynter D.I. Changes in activity of the manganese superoxide dismutase enzyme in tissues of the rat with changes in dietary manganese. J Nutr 1980, 110:437-447.
36. Primiano T., Li Y., Kensler T.W., Trush M.A., Sutter T.R. Identification of dithiolethione-inducible gene-1 as a leukotriene B4 12-hydroxydehydrogenase: implications for chemoprevention. Carcinogenesis 1998, 19:999-1005.
37. Quincozes-Santos A., Rosa R.B., Leipnitz G., de Souza D.F., Seminotti B., Wajner M., et al. Induction of S100B secretion in C6 astroglial cells by the major metabolites accumulating in glutaric acidemia type I. Metab Brain Dis 2010, 25:191-198.
38. Reaney S.H., Smith D.R. Manganese oxidation state mediates toxicity in PC12 cells. Toxicol Appl Pharmacol 2005, 205:271-281.
39. Roth J.A., Horbinski C., Higgins D., Lein P., Garrick M.D. Mechanisms of manganese-induced rat pheochromocytoma (PC12) cell death and cell differentiation. Neurotoxicology 2002, 23:147-157.
40. Satarug S., Kikuchi M., Wisedpanichkij R., Li B., Takeda K., Na-Bangchang K., et al. Prevention of cadmium accumulation in retinal pigment epithelium with manganese and zinc. Exp Eye Res 2008, 87:587-593.
41. Schaarschmidt J., Wischgoll S., Hofmann H.J., Boll M. Conversion of a decarboxylating to a non-decarboxylating glutaryl-coenzyme A dehydrogenase by site-directed mutagenesis. FEBS Lett 2011, 585:1317-1321.
42. Sengupta A., Mense S.M., Lan C., Zhou M., Mauro R.E., Kellerman L., et al. Gene expression profiling of human primary astrocytes exposed to manganese chloride indicates selective effects on several functions of the cells. Neurotoxicology 2007, 28:478-489.
43. Sok J., Calfon M., Lu J., Lichtlen P., Clark S.G., Ron D. Arsenite-inducible RNA-associated protein (AIRAP) protects cells from arsenite toxicity. Cell Stress Chaperones 2001, 6:6-15.
44. Strauss K.A., Lazovic J., Wintermark M., Morton D.H. Multimodal imaging of striatal degeneration in Amish patients with glutaryl-CoA dehydrogenase deficiency. Brain 2007, 130:1905-1920.
45. Vijayan V., Mueller S., Baumgart-Vogt E., Immenschuh S. Heme oxygenase-1 as a therapeutic target in inflammatory disorders of the gastrointestinal tract. World J Gastroenterol 2010, 16:3112-3119.
46. Wang J. Preclinical and clinical research on inflammation after intracerebral hemorrhage. Prog Neurobiol 2010, 92:463-477.
47. Whittle B.J., Varga C. New light on the anti-colitic actions of therapeutic aminosalicylates: the role of heme oxygenase. Pharmacol Rep 2010, 62:548-556.
48. Winder B.S., Salmon A.G., Marty M.A. Inhalation of an essential metal: development of reference exposure levels for manganese. Regul Toxicol Pharmacol 2010, 57:195-199.
49. Zhang P., Hatter A., Liu B. Manganese chloride stimulates rat microglia to release hydrogen peroxide. Toxicol Lett 2007, 173:88-100.
50. Zhao Z., Chen Y., Wang J., Sternberg P., Freeman M.L., Grossniklaus H.E., et al. Age-related retinopathy in NRF2-deficient mice. PloS One 2011, 6:e19456.