Manganese oxidation state mediates toxicity in PC12 cells

Toxicology and Applied Pharmacology

Volumn 205, Issue 3, 2005, Pages 271-281

  Reaney, S H ^a   Smith, D R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Dopamine; H ferritin; Iron regulation; Manganese oxidation state; Mn(II) and Mn(III); Neurotoxicity; Neurotransmitters; Oxidative stress; PC12; Serotonin; Toxicity; Transferrin receptor

Indexed keywords

ADENOSINE TRIPHOSPHATE; COPPER ZINC SUPEROXIDE DISMUTASE; DOPAMINE; FERRITIN; ISOPROSTANE DERIVATIVE; LACTATE DEHYDROGENASE; MANGANESE CHLORIDE; MANGANESE DERIVATIVE; MANGANESE PYROPHOSPHATE; MANGANESE SUPEROXIDE DISMUTASE; SEROTONIN; TRANSFERRIN RECEPTOR; TRYPAN BLUE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LEVEL; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; NONHUMAN; OXIDATION KINETICS; OXIDATIVE STRESS; RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; CATIONS; CELL SURVIVAL; CHLORIDES; DIPHOSPHATES; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FERRITINS; INTRACELLULAR FLUID; ISOPROSTANES; L-LACTATE DEHYDROGENASE; MANGANESE COMPOUNDS; PC12 CELLS; RATS; RECEPTORS, TRANSFERRIN; SEROTONIN; SUPEROXIDE DISMUTASE;

EID: 19444374381     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2004.10.013     Document Type: Article

References (60)

1. S.F. Ali, H.M. Duhart, G.D. Newport, G.W. Lipe, and W. Slikker Jr. Manganese-induced reactive oxygen species: comparison between Mn+2 and Mn+3 Neurodegeneration 4 1995 329 334
2. B. Almas, B. Le Bourdelles, T. Flatmark, J. Mallet, and J. Haavik Regulation of recombinant human tyrosine hydroxylase isozymes by catecholamine binding and phosphorylation. Structure/activity studies and mechanistic implications Eur. J. Biochem. 209 1992 249 255
3. F.S. Archibald, and C. Tyree Manganese poisoning and the attack of trivalent manganese upon catecholamines Arch. Biochem. Biophys. 256 1987 638 650
4. M. Aschner, and M. Gannon Manganese (Mn) transport across the rat blood-brain barrier: saturable and transferrin-dependent transport mechanisms Brain Res. Bull. 33 1993 345 349
5. M. Aschner, G. Shanker, K. Erikson, J. Yang, and L.A. Mutkus The uptake of manganese in brain endothelial cultures Neurotoxicology 23 2002 165 168
6. E.P. Brouillet, L. Shinobu, U. McGarvey, F. Hochberg, and M.F. Beal Manganese injection into the rat striatum produces excitotoxic lesions by impairing energy metabolism Exp. Neurol. 120 1993 89 94
7. S. Brown, and N.L. Taylor Could mitochondrial dysfunction play a role in manganese toxicity? Environ. Toxicol. Pharmacol. 7 1999 49 57
8. D. Cook, S. Fahn, and K. Brait Chronic manganese intoxication Arch. Neurol. 30 1974 59 64
9. W.C. Cooper The health implications of increased manganese in the environment resulting from the combustion of fuel additives: a review of the literature J. Toxicol. Environ. Health 14 1984 23 46
10. J.S. Crossgrove, D.D. Allen, B.L. Bukaveckas, S.S. Rhineheimer, and R.A. Yokel Manganese distribution across the blood-brain barrier: I. Evidence for carrier-mediated influx of manganese citrate as well as manganese and manganese transferrin Neurotoxicology 24 2003 3 13
11. K.S. Crump, and P. Rousseau Results from eleven years of neurological health surveillance at a manganese oxide and salt producing plant Neurotoxicology 20 1999 273 286
12. M.S. Desole, G. Esposito, R. Migheli, S. Sircana, M.R. Delogu, L. Fresu, M. Miele, G. de Natale, and E. Miele Glutathione deficiency potentiates manganese toxicity in rat striatum and brainstem and in PC12 cells Pharmacol. Res. 36 1997 285 292
13. D.T. Dexter, A. Carayon, F. Javoy-Agid, Y. Agid, F.R. Wells, S.E. Daniel, A.J. Lees, P. Jenner, and C.D. Marsden Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia Brain 114 Pt 4 1991 1953 1975
14. J.W. Finley, and C.D Davis Manganese deficiency and toxicity: are high or low dietary amounts of manganese cause for concern? BioFactors 10 1999 15 24
15. L.A. Finney, and T.V. O'Halloran Transition metal speciation in the cell: insights from the chemistry of metal ion receptors Science 300 2003 931 936
16. P. Galvani, P. Fumagalli, and A. Santagostino Vulnerability of mitochondrial complex I in PC12 cells exposed to manganese Eur. J. Pharmacol. 293 1995 377 383
17. M.D. Garrick, K.G. Dolan, C. Horbinski, A.J. Ghio, D. Higgins, M. Porubcin, E.G. Moore, L.N. Hainsworth, J.N. Umbreit, M.E. Conrad, L. Feng, A. Lis, J.A. Roth, S. Singleton, and L.M. Garrick DMT1: a mammalian transporter for multiple metals BioMetals 16 2003 41 54
18. C.E. Gavin, K.K. Gunter, and T.E. Gunter Manganese and calcium efflux kinetics in brain mitochondria. Relevance to manganese toxicity Biochem. J. 266 1990 329 334
19. J.M. Gorell, C.C. Johnson, B.A. Rybicki, E.L. Peterson, G.X. Kortsha, G.G. Brown, and R.J. Richardson Occupational exposures to metals as risk factors for Parkinson's disease Neurology 48 1997 650 658
20. L.A. Greene, and A.S. Tischler Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor Proc. Natl. Acad. Sci. U.S.A. 73 1976 2424 2428
21. T.E. Gunter, L.M. Miller, C.E. Gavin, R. Eliseev, J. Salter, L. Buntinas, A. Alexandrov, S. Hammond, and K.K. Gunter Determination of the oxidation states of manganese in brain, liver, and heart mitochondria J. Neurochem. 88 2004 266 280
22. D. HaMai, A. Campbell, and S.C. Bondy Modulation of oxidative events by multivalent manganese complexes in brain tissue Free Radical Biol. Med. 31 2001 763 768
23. J. Kaiser Manganese: a high-octane dispute Science 300 2003 926 928
24. J. Kaiser State Court to rule on manganese fume claims Science 300 2003 927
25. R.H. Kenton, and P.J.G. Mann The oxidation of manganese by illuminated chloroplast preparations Biochem. J. 61 1955 279 286
26. C.L. Kwik-Uribe, S. Reaney, Z.W. Zhu, and D. Smith Alterations in cellular IRP-dependent iron regulation by in vitro manganese exposure in undifferentiated PC12 cells Brain Res. 973 2003 1 15
27. R.V. Lloyd Mechanism of the manganese-catalyzed autoxidation of dopamine Chem. Res. Toxicol. 8 1995 111 116
28. R. Lucchini, P. Apostoli, C. Perrone, D. Placidi, E. Albini, P. Migliorati, D. Mergler, M.P. Sassine, S. Palmi, and L. Alessio Long-term exposure to "low levels" of manganese oxides and neurofunctional changes in ferroalloy workers Neurotoxicology 20 1999 287 297
29. L.L. McLaughlin, Y.F. Wei, P.T. Stockmann, K.M. Leahy, P. Needleman, J. Grassi, and P. Pradelles Development, validation and application of an enzyme immunoassay (EIA) of atriopeptin Biochem. Biophys. Res. Commun. 144 1987 469 476
30. D. Mergler, M. Baldwin, S. Belanger, F. Larribe, A. Beuter, R. Bowler, M. Panisset, R. Edwards, A. de Geoffroy, M.P. Sassine, and K. Hudnell Manganese neurotoxicity, a continuum of dysfunction: results from a community based study Neurotoxicology 20 1999 327 342
31. J. Morgan Manganese and Its Role in Biological Processes 2000 Marcel Dekker New York
32. J.D. Morrow, B. Frei, A.W. Longmire, J.M. Gaziano, S.M. Lynch, Y. Shyr, W.E. Strauss, J.A. Oates, and L.J. Roberts II Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage N. Engl. J. Med. 332 1995 1198 1203
33. P.K. Pal, A. Samii, and D.B. Calne Manganese neurotoxicity: a review of clinical features, imaging and pathology Neurotoxicology 20 1999 227 238
34. K.M. Powers, T. Smith-Weller, G.M. Franklin, W.T. Longstreth Jr., P.D. Swanson, and H. Checkoway Parkinson's disease risks associated with dietary iron, manganese, and other nutrient intakes Neurology 60 2003 1761 1766
35. P. Pradelles, J. Grassi, and J. Maclouf Enzyme immunoassays of eicosanoids using acetylcholine esterase as label: an alternative to radioimmunoassay Anal. Chem. 57 1985 1170 1173
36. B.A. Racette, L. McGee-Minnich, S.M. Moerlein, J.W. Mink, T.O. Videen, and J.S. Perlmutter Welding-related parkinsonism: clinical features, treatment, and pathophysiology Neurology 56 2001 8 13
37. S.H. Reaney, C.L. Kwik-Uribe, and D.R. Smith Manganese oxidation state and its implications for toxicity Chem. Res. Toxicol. 15 2002 1119 1126
38. T. Ressler, J. Wong, J. Roos, and I.L. Smith Quantitative speciation of Mn-bearing particulates emitted from autos burning (methylcyclopentadienyl) manganese tricarbonyl-added gasolines using XANES spectroscopy Environ. Sci. Technol. 34 2000 950 958
39. P. Riederer, E. Sofic, W.D. Rausch, B. Schmidt, G.P. Reynolds, K. Jellinger, and M.B. Youdim Transition metals, ferritin, glutathione, and ascorbic acid in parkinsonian brains J. Neurochem. 52 1989 515 520
40. J.A. Roth, and M.D. Garrick Iron interactions and other biological reactions mediating the physiological and toxic actions of manganese Biochem. Pharmacol. 66 2003 1 13
41. J. Segura-Aguilar, and C. Lind On the mechanism of the Mn3(+)-induced neurotoxicity of dopamine: prevention of quinone-derived oxygen toxicity by DT diaphorase and superoxide dismutase Chem. Biol. Interact. 72 1989 309 324
42. K. Seki, H.C. Chen, and K.P. Huang Dephosphorylation of protein kinase C substrates, neurogranin, neuromodulin, and MARCKS, by calcineurin and protein phosphatases 1 and 2A Arch. Biochem. Biophys. 316 1995 673 679
43. Silva, J.R.R.F.d., Williams, R.J.P., 1991. The Biological Chemistry of the Elements: The Inorganic Chemistry of Life. Clarendon Press; Oxford Univ. Press, Oxford England, New York.
44. E. Sofic, P. Riederer, H. Heinsen, H. Beckmann, G.P. Reynolds, G. Hebenstreit, and M.B. Youdim Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain J. Neural Transm. 74 1988 199 205
45. M.N. Subhash, and T.S. Padmashree Effect of manganese on biogenic amine metabolism in regions of the rat brain Food Chem. Toxicol. 29 1991 579 582
46. I. Sziraki, K.P. Mohanakumar, P. Rauhala, H.G. Kim, K.J. Yeh, and C.C. Chiueh Manganese: a transition metal protects nigrostriatal neurons from oxidative stress in the iron-induced animal model of parkinsonism Neuroscience 85 1998 1101 1111
47. Y. Tampo, and M. Yonaha Antioxidant mechanism of Mn(II) in phospholipid peroxidation Free Radical Biol. Med. 13 1992 115 120
48. K.H. Thompson, and C. Orvig Boon and bane of metal ions in medicine Science 300 2003 936 939
49. A.S. Tischler, and L.A. Greene Morphologic and cytochemical properties of a clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor Lab. Invest. 39 1978 77 89
50. J.F. Turrens Superoxide production by the mitochondrial respiratory chain Biosci. Rep. 17 1997 3 8
51. E.J. Underwood Trace Elements in Human and Animal Nutrition 1977 Academic Press New York
52. C. Velez-Pardo, M. Jimenez Del Rio, H. Verschueren, G. Ebinger, and G. Vauquelin Dopamine and iron induce apoptosis in PC12 cells Pharmacol. Toxicol. 80 1997 76 84
53. C. Velez-Pardo, M.J. Del Rio, G. Ebinger, and G. Vauquelin Monoamine and iron-related toxicity: from "serotonin-binding proteins" to lipid peroxidation and apoptosis in PC12 cells Gen. Pharmacol. 31 1998 19 24
54. A. Vescovi, L. Facheris, A. Zaffaroni, G. Malanca, and E.A. Parati Dopamine metabolism alterations in a manganese-treated pheochromocytoma cell line (PC12) Toxicology 67 1991 129 142
55. Z. Wang, G. Ciabattoni, C. Creminon, J. Lawson, G.A. Fitzgerald, C. Patrono, and J. Maclouf Immunological characterization of urinary 8-epi-prostaglandin F2 alpha excretion in man J. Pharmacol. Exp. Ther. 275 1995 94 100
56. R. Witholt, R.H. Gwiazda, and D.R. Smith The neurobehavioral effects of subchronic manganese exposure in the presence and absence of pre-parkinsonism Neurotoxicol. Teratol. 22 2000 851 861
57. C.G. Worley, D. Bombick, J.W. Allen, R.L. Suber, and M. Aschner Effects of manganese on oxidative stress in CATH.a cells Neurotoxicology 23 2002 159 164
58. C.F. Yocum, and V.L. Pecoraro Recent advances in the understanding of the biological chemistry of manganese [Review] Curr. Opin. Chem. Biol. 3 1999 182 187
59. W. Zheng, and Q. Zhao Iron overload following manganese exposure in cultured neuronal, but not neuroglial cells Brain Res. 897 2001 175 179
60. W. Zheng, Q. Zhao, V. Slavkovich, M. Aschner, and J.H. Graziano Alteration of iron homeostasis following chronic exposure to manganese in rats Brain Res. 833 1999 125 132