Burn-induced apoptosis of cardiomyocytes is survivin dependent and regulated by PI3K/Akt, p38 MAPK and ERK pathways

Basic Research in Cardiology

Volumn 106, Issue 6, 2011, Pages 1207-1220

  Cao, Wei ^a   Xie, Yan Hua ^a   Li, Xiao Qiang ^a   Zhang, Xiao Kai ^a   Chen, Yue Tao ^a   Kang, Rong ^a   Chen, Xi ^a   Miao, Shan ^a   Wang, Si Wang ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Burn injury; Cardiomyocyte; MAPK; PI3K; Survivin

Indexed keywords

CASPASE 3; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SEPANTRONIUM BROMIDE; SURVIVIN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BODY SURFACE; BURN; CASPASE 3 GENE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME REGULATION; GENE; HEART MUSCLE CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BURNS; CYTOKINES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEART VENTRICLES; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MAP KINASE SIGNALING SYSTEM; MICROTUBULE-ASSOCIATED PROTEINS; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84856741780     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-011-0199-3     Document Type: Article

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