Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): Anti-inflammatory and anti-cancer properties

International Immunopharmacology

Volumn 12, Issue 2, 2012, Pages 368-377

  Olivera, Anlys ^a   Moore, Terry W ^b   Hu, Fang ^a   Brown, Andrew P ^b   Sun, Aiming ^b   Liotta, Dennis C ^b   Snyder, James P ^b   Yoon, Younghyoun ^a,b   Shim, Hyunsuk ^a,b   Marcus, Adam I ^a,b   Miller, Andrew H ^a,b   Pace, Thaddeus W W ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

Anti cancer; Curcumin; Inflammation; Macrophages; NF B

Indexed keywords

3,5 BIS(2 FLUOROBENZYLIDENE) 4 PIPERIDONE; 3,5 BIS(2 PYRIDINYLMETHYLIDENE) 4 PIPERIDONE; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CURCUMIN; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; DNA BINDING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; BENZYLIDENE COMPOUNDS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CURCUMIN; DNA-BINDING PROTEINS; I-KAPPA B KINASE; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NF-KAPPA B; PHOSPHORYLATION; PIPERIDONES; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84856741618     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.12.009     Document Type: Article

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