Islet autoantibody seroconversion in the DPT-1 study: Justification for repeat screening throughout childhood

Diabetes Care

Volumn 34, Issue 2, 2011, Pages 358-362

  Vehik, Kendra ^a   Haller, Michael J ^b   Beam, Craig A ^a   Schatz, Desmond A ^b   Wherrett, Diane K ^c   Sosenko, Jay M ^d   Krischer, Jeffrey P ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF MIAMI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; DIABETES ASSOCIATED AUTOANTIBODY; GLUTAMATE DECARBOXYLASE 65; PANCREAS ISLET CELL ANTIBODY; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; AUTOIMMUNITY; CHILD; CHILDHOOD; CLINICAL ASSESSMENT; COHORT ANALYSIS; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; SCHOOL CHILD; SCREENING TEST; SEROCONVERSION;

ADOLESCENT; AGE DISTRIBUTION; AGE OF ONSET; AUTOANTIBODIES; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; FEMALE; GLUTAMATE DECARBOXYLASE; HUMANS; ISLETS OF LANGERHANS; MALE; MASS SCREENING; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 8; RISK FACTORS; SEROEPIDEMIOLOGIC STUDIES;

EID: 79951713180     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc10-1494     Document Type: Article

References (11)

1. Krischer JP, Cuthbertson DD, Yu L, et al. Screening strategies for the identification of multiple antibody-positive relatives of individuals with type 1 diabetes. J Clin Endocrinol Metab 2003;88:103-108 (Pubitemid 36115150)
2. Riley WJ, Maclaren NK, Krischer J, et al. A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes. N Engl J Med 1990;323:1167-1172
3. Achenbach P, Warncke K, Reiter J, et al. Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics. Diabetes 2004;53:384-392 (Pubitemid 38174554)
4. Colman PG, McNair PD, Gellert S, et al. Development of autoantibodies to islet antigens during childhood: implications for preclinical type 1 diabetes screening. Pediatr Diabetes 2002;3:144-148 (Pubitemid 35203521)
5. Diabetes Prevention Trial-Type 1 Diabetes Study Group. Effects of insulin in relatives of patients with type 1 diabetes mellitus. N Engl J Med 2002;346:1685-1691
6. Greenbaum CJ, Cuthbertson D, Krischer JP; Disease Prevention Trial of Type I Diabetes Study Group. Type I diabetes manifested solely by 2-h oral glucose tolerance test criteria. Diabetes 2001;50:470-476
7. Yu L, Rewers M, Gianani R, et al. Antiislet autoantibodies usually develop sequentially rather than simultaneously. J Clin Endocrinol Metab 1996;81:4264-4267 (Pubitemid 26412027)
8. Williams AJ, Bingley PJ, Bonifacio E, Palmer JP, Gale EA. A novel micro-assay for insulin autoantibodies. J Autoimmun 1997;10:473-478 (Pubitemid 27433643)
9. Efron B. The efficiency of Cox's likelihood function for censored data. J Am Stat Assoc 1977;72:557-565
10. Pilcher CC, Dickens K, Elliot RB. ICA only develop in early childhood (Abstract). Diabetes Res Clin Pract 1991;14:582
11. Patterson CC, Dahlquist GG, Gyürüs E, Green A, Soltész G; EURODIAB Study Group. Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study. Lancet 2009;373:2027-2033